Abstract：
BACKGROUND AND OBJECTIVE:Our goal was to analyze the epidemiological and clinical findings, as well as the diagnostic approach in a group of patients in whom uveitis was the first manifestation of sarcoidosis. PATIENTS AND METHOD:Retrospective study (between March 1998 and July 2002) including 31 patients diagnosed with sarcoidosis after an episode of uveitis. The group consisted of 19 females (61%) and 12 males (39%). Mean follow-up was 34.5 months. Age, sex, ocular and systemic clinical findings were recorded. Angiotensin converting enzyme (ACE) levels were measured and radiological studies of the thorax were conducted including simple radiography (Rx), computerized axial tomography (CT) and gallium scan (67Ga). Biopsy was carried out in 14 patients. RESULTS:Mean age was 59.6 years. Six different clinical presentations of uveitic sarcoidosis were observed, the most common being bilateral panuveitis in 13 patients (42%) and chronic anterior bilateral uveitis in 11 (35%). Gallium scan, thoracic CT and chest radiography were positive in 88%, 77% and 33% cases, respectively. ACE levels were raised in 7 of the 27 patients analyzed (26%). Histological confirmation of disease was obtained in all 14 patients biopsied with a specificity and sensitivity of 100%. CONCLUSIONS:Uveitis may be the presenting manifestation of sarcoidosis, especially in women over 60 years of age. Bilateral panuveitis and chronic bilateral anterior uveitis are the most common clinical presentations. The sensitivity of gallium scan and thoracic CT is greater than simple chest radiography in diagnosing pulmonary and mediastinal lesions of sarcoidosis. The need for biopsy should be individualized in each case depending on complementary exams, age and potential morbidity of the procedure.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Adán A,Baget M,De Llobet JM,Segura A,Marieges MT,Casaroli-Marano Rdoi
10.1016/s0025-7753(04)74374-2keywords:
subject
Has Abstractpub_date
2004-05-22 00:00:00pages
748-52issue
19eissn
0025-7753issn
1578-8989pii
S0025-7753(04)74374-2journal_volume
122pub_type
杂志文章相关文献
MEDICINA CLINICA文献大全abstract：BACKGROUND:Asthma is one of the more prevalent diseases in childhood. Geographical differences have been found but it is unknown if they are true or are a consequence of the different methods used in the study of asthma. POPULATION AND METHODS:In 9 Spanish populations: Almería, Barcelona, Bilbao, Bahía de Cádiz, Carta...
journal_title：Medicina clinica
pub_type： 杂志文章,多中心研究
doi：
更新日期：1999-02-13 00:00:00
abstract：:The association of celiac disease, epilepsy and occipital calcifications with initial clinical manifestations of epilepsy during the first two decades of life with an often progressive and variable course and clinical expression of malabsorption has recently been described. Two cases of celiac disease with occipital c...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1995-12-08 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The suitable antibiotic(s) and duration of treatment for hip prosthesis acute infections (HPAIs) has not been clearly defined. PATIENTS AND METHOD:We studied 32 patients whose HPAI was diagnosed within 2 months after surgery. All patients underwent debridement and samples were taken for cultur...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(03)73863-9
更新日期：2003-06-21 00:00:00
abstract：:The main objective is to detail the main biases in the study of prognostic factors. Confounding bias is illustrated with social class, a prognostic factor still discussed. Within selection bias several cases are commented: response bias, specially frequent when the patients of a clinical trial are used; the shortcomin...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：
更新日期：1999-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Functional assessment is especially relevant in patients with cognitive impairment (CI). The Disability Assessment for Dementia (DAD) scale assesses functional ability and its use is becoming increasingly popular. This study aims to perform the translation and cultural adaptation of the DAD sca...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2017.03.029
更新日期：2017-09-20 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The ankle-brachial index allows for the detection of subclinical cardiovascular disease and risk, by diagnosing peripheral arterial disease and arterial calcification. Asymptomatic hypertensive men, between 45-55 years and with the suspicion of low risk, could be an important population group t...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2014.02.028
更新日期：2015-05-21 00:00:00
abstract：BACKGROUND:To examine whether provincial mortality from ischaemic heart disease and cerebrovascular disease in Spain in 1991-1995 is associated with infant mortality in 1930-1934, independently of illiteracy (an estimator of socioeconomic status) in 1991. MATERIAL AND METHODS:Population-correlation study. RESULTS:Inf...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1999-10-16 00:00:00
abstract：BACKGROUND:There is poor information for isolated clinical tachycardia (ICT), that is to say, office tachycardia but normal ambulatory heart rate (HR). Our objective was to describe it and to know differences between hypertensive subjects with and without ICT. PATIENTS AND METHOD:Comparative study after a diagnostic i...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(00)71627-7
更新日期：2000-11-04 00:00:00
abstract：BACKGROUND:To determine the risk factors for the development of atopy in Spanish young adults. SUBJECTS AND METHODS:Case-control study over prevalent cases. Carried out in general population between the ages of 20 to 44 years old. Spanish participants of the ECRHS, a random representative sample of Spanish young adult...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(00)71231-0
更新日期：2000-02-12 00:00:00
abstract：BACKGROUND:The aim of this study was the assessment of the scientific production and impact on academic and/or hospital promotion ob sabbatical leaves of medical staff from a University hospital. POPULATION AND METHODS:A matched case-control design was used. The Mantel-Haenszel odds ratio (ORMH) and its 95% confidence...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1998-10-03 00:00:00
abstract：BACKGROUND AND OBJECTIVE:To determine the accuracy of clinical gestalt to identify patients with acute symptomatic pulmonary embolism (PE) at low-risk for short-term complications. PATIENTS AND METHODS:This study included a total of 154 consecutive patients diagnosed with acute symptomatic PE in a tertiary university ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2017.11.023
更新日期：2018-08-22 00:00:00
abstract：BACKGROUND:Advanced atrioventricular block (AB) during acute myocardial infarction (AMI), characterizes a high-risk subgroup of patients. Our aim was to determine the prognostic significance of AB and its possible peculiarities in relation to infarction localization and/or the thrombolytic therapy. PATIENTS AND METHOD...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(00)71282-6
更新日期：2000-03-11 00:00:00
abstract：BACKGROUND:To evaluate the diagnostic power of serum myoglobin (Mgb) by latex agglutination as a marker in the first hours of acute myocardial infarction (AMI). METHODS:Two hundred forty-eight serum samples from 53 patients admitted to the Coronary Unit (CU) from the Emergency Department (ED) for suspected AMI were st...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1992-07-04 00:00:00
abstract：:Through the Law 2/2004 on improving neighbourhoods, urban areas and towns requiring special attention, the Government of Catalonia set up a fund for financing projects prepared by town/city councils for the integral improvement of neighbourhoods. The Ministry of Health signed on to the strategy with The Neighbourhood ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(08)76477-7
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND:To assess how patients with diabetes experience their condition. PATIENTS AND METHOD:Pilot study conducted in 10 selected patients with type 1 diabetes. A structured interview guide was prepared including physical, social and emotional areas. The information provided was analyzed qualitatively, key statemen...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The aims of the present study were to analyze the prognosis after resuscitation from out-of-hospital sudden cardiac death in patients admitted to the coronary care unit, and to identify the predictor variables of morbi-mortality. PATIENTS AND METHOD:From November 1999 to January 2004 we analyz...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(06)72232-1
更新日期：2006-09-02 00:00:00
abstract：BACKGROUND:The aim of the present study was to validate the SpaceLabs 90207 apparatus used in non-invasive outpatient monitoring of blood pressure. METHODS:The measurements of blood pressure (BP) and cardiac frequency (CF) obtained with the SpaceLabs monitor were compared with those obtained with a mercury sphygmomano...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1994-09-24 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The progressive accumulation of iron in the organism contribute to one of the most important problems of morbidity and mortality in patients with myelodysplastic syndrome (MDS). We present an observational protocol, multicentre, open and non-aleatheorised, in patients diagnosed with MDS on tran...
journal_title：Medicina clinica
pub_type： 杂志文章,多中心研究
doi：10.1157/13074739
更新日期：2005-05-07 00:00:00
abstract：:We have evaluated the close contacts of 191 patients diagnosed of tuberculosis in our center between 1984 and 1987. The overall number of evaluated contacts was 666, and the mean number of contacts for each index case was 3.7. In 55% of the evaluated population PPD reaction was positive, and their mean age was 33.3 ye...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1989-04-22 00:00:00
abstract：:The authors present a study of 50 patients with adenocarcinomas of the colon and rectum, patients with gastric adenocarcinomas, and 30 healthy individuals as a control group. In all subjects the following parameters were determined: total number of lymphocytes in the peripheral blood, T lymphocytes, T-active lymphocyt...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1979-12-15 00:00:00
abstract：:Non-alcoholic fatty liver disease (NAFLD) consists of an excessive depositing of fat in the liver, which can end up by causing inflammation, fibrosis and also cirrhosis with the corresponding complications including liver cancer. NAFLD has become the most common liver disease worldwide. The incidence has increased in ...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：10.1016/j.medcli.2017.06.026
更新日期：2017-12-20 00:00:00
abstract：BACKGROUND:The presence of cagA antibodies constitutes a serum marker of infection caused by virulent strains of Helicobacter pylori. The objective of this study was to determine the risk of peptic ulcer in patients with H. pylori infection, in relation to the detection of CagA and VacA antibodies. PATIENTS AND METHOD...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：2001-05-12 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The use of complementary and alternative medicine (CAM) is increasing in last years. Studies performed out of Spain have reported rates of CAM use of 40-50% among IBD patients. There are no available data on drug abuse among IBD patients. The aims of our study were to evaluate the rate and asso...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13097468
更新日期：2007-01-20 00:00:00
abstract：:To evaluate the clinical and microbiological features of infective endocarditis in patients with cirrhosis we compared 18 episodes of endocarditis in these patients with a control group of patients without liver disease. In 61% of patients with cirrhosis the origin of infection was unknown. Four patients developed end...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1989-11-11 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to evaluate the ability of long-term highly active antiretroviral therapy (HAART) to fully reconstitute the immune system in children with severe AIDS. PATIENT AND METHOD:Lymphoproliferative responses (LPR) were evaluated by incorporation of [3H]-thymidine. Cytokine p...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(03)73723-3
更新日期：2003-03-29 00:00:00
abstract：:The familial periodic hypokalemic paralysis is an infrequent disease characterized by paralytic attacks of sudden appearance affecting the muscles of the trunk and limbs. There is a marked hypokalemia during the paralytic episodes of the disease, and a family history in 80 percent of the cases. The differential diagno...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1980-03-10 00:00:00
abstract：:Fifteen cases of cutaneous larva migrans (CLM) diagnosed in transcontinental travellers over a period of 4 years in the Department of Tropical Medicine in Hospital Clinic i Provincial of Barcelona were reviewed. The frequency of this disease as an imported pathology is on the increase and is related to the greater mob...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：
更新日期：1992-02-15 00:00:00
abstract：BACKGROUND AND OBJECTIVE:To know the frequency of nosocomial infection (NI) in surgical hip fracture patients and to analyze the risk factors that favor the NI development, especially its relationship with allogeneic blood transfusion (ABT) and intravenous iron administration. PATIENTS AND METHOD:Unicenter prospective...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13128722
更新日期：2008-11-15 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Although elder abuse is not a new phenomenon, it remains hidden. There have been carried out various preliminary studies about the prevalence of elder abuse in different countries. The aim of this study is to estimate the prevalence of suspicion of elder abuse in old persons without cognitive i...
journal_title：Medicina clinica
pub_type： 杂志文章,多中心研究
doi：10.1016/j.medcli.2012.09.048
更新日期：2013-12-21 00:00:00
abstract：:We present the two first Spanish cases about the endodermic heterotopia of the atrioventricular node. This is an infrequent and probably congenital lesion, with a not well known histogenesis and associated with heart blocks and sudden death, which affects women in most cases. The first observation attaches a 55 years-...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：
更新日期：1995-02-25 00:00:00
