Abstract：
OBJECTIVE:In December 2019, Wuhan, China, experienced an outbreak of coronavirus disease 2019 (COVID-19). Some patients admitted to our hospital were treated with early prone positioning (PP). Here, we analyzed its clinical significance. METHODS:This was a retrospective observational study. We defined the early PP group as mild COVID-19 patients who were placed into a prone position within 24h of admission; others served as the control group. We recorded basic data and outcomes of early PP and compared the results to those of controls. RESULTS:After 1 day of treatment, oxygenation was greater in the early PP group than in the control group (P/F: 421.6±39.74 vs. 382.1±38.84mmHg [1mmHg=0.133kPa], p<0.01). And early PP group spent less total time in prone position (11.1±4.17 vs. 16.9±5.20 days, p<0.01), and required shorter hospitalization duration (12.2±4.49 vs. 23.2±4.83 days, p<0.001). CONCLUSIONS:Early PP treatment can improve hypoxia and shorten the prone position time and hospitalization duration in mild COVID-19 patients. It is a potential clinically applicable intervention.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Liu X,Liu H,Lan Q,Zheng X,Duan J,Zeng Fdoi
10.1016/j.medcli.2020.11.036subject
Has Abstractpub_date
2020-12-26 00:00:00eissn
0025-7753issn
1578-8989pii
S0025-7753(20)30884-8pub_type
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