Abstract：
BACKGROUND AND OBJECTIVE:The correct management of patients with chronic renal disease depends on an early diagnosis. The aim of this study was to evaluate the usefulness, in the daily clinical practice, of the weight/creatinine formula as an indirect measurement of glomerular filtration. PATIENTS AND METHOD:1,025 ambulatory patients were referred to the Nephrology Laboratory for basic blood and urine analysis. Creatinine clearance was calculated with the standard formula. RESULTS:A good correlation between the creatinine clearance adjusted for the corporal surface and that estimated by the weight/creatinine formula was observed, especially when creatinine levels were between 1.5-3 mg/dl and patients were older than 60 years. The mean difference between both methods was 6.3 (14.5) ml/min for males and 2.4 (10.5) ml/min for females. The weight/creatinine formula had a sensitivity of 91% and a specificity of 80% to detect a clearance below 50 ml/min. CONCLUSIONS:The weight/creatinine formula underestimates the clearance for normal creatinine values but fits quite well for creatinine levels between 1.5-3 mg/dl, mainly in patients older than 60 years. Although the estimation of clearance through this formula could be inaccurate, in most cases this is clinically irrelevant. Moreover, such a simple formula could avoid potential mistakes appearing at the time of evaluating renal function only by the serum creatinine.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Fernández-Fresnedo G,Martín de Francisco AL,Rodrigo Calabia E,Ruiz San Millán JC,Sanz de Castro S,Arias Rodríguez Mdoi
10.1016/s0025-7753(03)73751-8keywords:
subject
Has Abstractpub_date
2003-04-12 00:00:00pages
485-8issue
13eissn
0025-7753issn
1578-8989pii
S0025-7753(03)73751-8journal_volume
120pub_type
杂志文章相关文献
MEDICINA CLINICA文献大全abstract：BACKGROUND:To identify and to compare the recommendations of the currently existing clinical protocols for arterial hypertension (HT) screening, diagnosis and baseline study in the Murcia Region, Spain, in order to assess their validity and reliability. MATERIAL AND METHODS:Structured comparative description of guidel...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:Bacillary angiomatosis (epithelioid) is a recently described clinicopathologic syndrome, principally associated to infection by the human immunodeficiency virus. The case of a patient who was seen for fever and the appearance of four painful, erythematous and indurated subcutaneous nodules on the anteroexternal face o...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：
更新日期：1993-06-12 00:00:00
abstract：:Epstein-Barr virus (EBV) infection is ubiquitous and may result in multiple and widely different clinical features; the most common of these is infectious mononucleosis (IM). Recently, a group of patients has been included in the chronic EBV infection syndrome (EBVIS), with a sustained nonspecific syndrome consisting ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1989-04-29 00:00:00
abstract：:Systemic vasculitis is a disease whose prognosis has improved considerably with steroid and immunosuppressive treatment, which points up the importance of early diagnosis. In elderly, diagnosis is made more difficult because the frequent onset in the form of a febrile syndrome with non-specific disturbances in general...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1992-04-18 00:00:00
abstract：BACKGROUND AND OBJECTIVE:To establish the seroprevalence of infection by Borrelia burgdorferi in Navarre (Spain). PATIENTS AND METHOD:Serum samples of 1,429 individuals considered representative of the population of Navarre were analyzed. The individuals were recruited from a list issued by the government of Navarre. ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2010.06.008
更新日期：2011-03-26 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The influence of homocysteine metabolism on the prognosis of acute coronary syndrome without ST elevation is controversial. PATIENTS AND METHOD:Prospective study of 109 patients admitted because of acute coronary syndrome without ST elevation. Basal plasmatic levels of homocysteine and folates...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13109705
更新日期：2007-09-08 00:00:00
abstract：BACKGROUND AND OBJECTIVE:This study was aimed to verify whether it is possible to detect at hospital admission, by means of INTERMED, pneumonology patients at risk of "complexity" and of specialized psychosocial intervention. PATIENTS AND METHOD:With the Spanish version of INTERMED (for detection of risk for complexit...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(08)75487-3
更新日期：2008-11-29 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The association of an exaggerated systolic blood pressure increase with exercise (EBPIE) with cardiovascular events remains controversial. Our aim was to determine the possible association of an EBPIE with survival and risk of serious cardiac events in patients with hypertension and known or su...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2016.09.016
更新日期：2017-01-20 00:00:00
abstract：:Pharmacogenetics studies the relationship between genetic polymorphisms and individual responses to drugs. In recent years, there has been a great progress in our knowledge of the effects of drug-metabolizing enzymes and molecular target genetic polymorfisms on cancer chemotherapy. Pharmacogenetics focuses on the pred...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：10.1157/13124283
更新日期：2008-07-05 00:00:00
abstract：:The familial periodic hypokalemic paralysis is an infrequent disease characterized by paralytic attacks of sudden appearance affecting the muscles of the trunk and limbs. There is a marked hypokalemia during the paralytic episodes of the disease, and a family history in 80 percent of the cases. The differential diagno...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1980-03-10 00:00:00
abstract：:A 75 year-old male presented with hyperkalemia unexplained by a moderate renal insufficiency, low basal levels of aldosterone and renin with a subnormal response to walking and saline depletion, and normal glucocorticoid function. The hyperkalemia was corrected by fluorocortisone administration. The concept of hypoald...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1980-11-10 00:00:00
abstract：BACKGROUND:Hip fractures are a major source of mortality and morbidity among the elderly. The aim of the present study is to try to identify predictors of death and of non-deambulation during the period of acute treatment. PATIENTS AND METHODS:Consecutive prospective study of 459 patients older than 65 years admitted ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1998-05-23 00:00:00
abstract：OBJECTIVE:In December 2019, Wuhan, China, experienced an outbreak of coronavirus disease 2019 (COVID-19). Some patients admitted to our hospital were treated with early prone positioning (PP). Here, we analyzed its clinical significance. METHODS:This was a retrospective observational study. We defined the early PP gro...
journal_title：Medicina clinica
pub_type：
doi：10.1016/j.medcli.2020.11.036
更新日期：2020-12-26 00:00:00
abstract：BACKGROUND:The aim of this study was to analyze the predictive factors of IDDM in first degree relatives of IDDM patients. SUBJECTS AND METHODS:From 1992 to 1994, 1,053 first degree relatives were screened for measuring islet cell antibodies (ICA) by indirect immunofluorescence (iFl). In all ICA positive subjects, bet...
journal_title：Medicina clinica
pub_type： 杂志文章,多中心研究
doi：
更新日期：1996-09-28 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Acute myeloid leukemia (AML) is the most frequent type of acute leukemia in adults. Despite recent advances in the characterization of pathogenesis of AML, the cure rates are under 40%, being leukemia relapse the most common cause of treatment failure. Leukaemia relapse occurs due to clonal evo...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2016.05.015
更新日期：2016-09-02 00:00:00
abstract：BACKGROUND:Human obesity is a widespread disease with considerable variability as to its severity, metabolic and endocrine manifestations and etiology. In the present study we have determined whether the alterations of uncomplicated severe obesity in adult young women affect with different intensity the circulating lev...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(01)71815-5
更新日期：2001-03-10 00:00:00
abstract：:Atherosclerotic renovascular disease is a common entity, particularly in persons older than 50 years of age and especially in those patients with other evidence of atherosclerotic vascular disease. The illness clearly progresses in some patients, and progression rate appears to be highly variable. Taken into account t...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1997-04-12 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Our objective was to analyze those factors predisposing to delirium in patients older than 84 years who were admitted because of hip fracture. We also compared the prevalence of delirium in this population with a younger group. PATIENTS AND METHOD:One hundred and thirty patients (mean age 91.8...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13073940
更新日期：2005-04-16 00:00:00
abstract：OBJECTIVE:To determine if a more simplified medication regimen is associated with survival in polypathological patients. METHODS:Multicentre cohort study. We included polypathological patients admitted to internal medicine wards between March 1st and June 30rd, 2011. Patients that died during admission and readmission...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2019.06.023
更新日期：2020-04-10 00:00:00
abstract：BACKGROUND AND OBJECTIVE:An important input to decision-making and health planning is a consistent and comparative description of the population health status. The purpose of this study was to describe the burden of disease in the Region of Valencia (Spain). MATERIAL AND METHODS:Disability-adjusted life years (DALYs) ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2012.01.028
更新日期：2013-04-20 00:00:00
abstract：:Pseudomonas infections continue to be an important problem in the hospital environment. Serious infections are always invariably associated with severe underlying conditions or with diminished host resistance. The increasingly resistance of strains and hospital epidemics favour the organism prevalence. During 1978, Ps...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1980-07-15 00:00:00
abstract：:Osteoarthritis and osteoporosis are both common conditions in the elderly but their association has long remained obscure. Recently published studies show that patients with osteoarthritis have higher bone mass but no corresponding decrease in fracture risk. This has been proposed to be due to an increased rate of fal...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：10.1016/j.medcli.2013.01.036
更新日期：2013-09-07 00:00:00
abstract：:Spain is one of the european countries with a lowest mortality rate by cardiovascular diseases (although they are the leading cause of mortality) and, specifically, by ischemic heart disease. The trends in the last 16 years for which data are available point to a reduction of the former in 1.07% in males and 1.53% in ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1989-10-28 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Several models for the prediction of liver fibrosis have been developed which consist of the measurement of routine laboratory data: a) a model combining platelets, gamma-glutamil-transpeptidase, cholesterol and age (Forns model), and b) a model using an aspartate-aminotransferase to platelet r...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13075845
更新日期：2005-05-28 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to investigate the presence of the most prevalent mutation in the SLC7A9 gene in families of the Mediterranean Spanish population and their association with clinical phenotypes. PATIENTS AND METHOD:Twenty cystinuria families were studied (6 type I, 12 non type I, and ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13090704
更新日期：2006-07-01 00:00:00
abstract：:To evaluate the economic impact of osteoporosis, the cost of acute attention to the osteoporotic hip fractures recorded in Barcelona during one year was investigated. The hospital records of 8637 beds (85.64% of the overall number in the city) were reviewed and the cases seen in inhabitants aged 45 years or more durin...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1989-05-20 00:00:00
abstract：BACKGROUND:The most appropriate methods for surveillance of nosocomial infection (NI) in hospitals with less than 250 beds remain to be elucidated. The aims of this study were to investigate the differences between the results found in a study in incidence (IS) and in another concerning prevalence (PS) carried out in a...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1993-01-16 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Clinical variability in myocardial infarction (MI) regarding age, comorbidities and atypical symptoms could determine gender differences in inhospital care. This study analyzes the magnitude and determinants of differences between men and women in early reperfusion therapy in people hospitalize...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(07)72497-1
更新日期：2007-01-27 00:00:00
abstract：:Community-acquired pneumonia (CAP) is an infectious respiratory disease with an incidence that ranges from 3 to 8 cases per 1,000 inhabitants per year. This incidence increases with age and comorbidities. Forty per cent of CAP patients require hospitalization and around 10% of these patients are admitted in an Intensi...
journal_title：Medicina clinica
pub_type： 共识发展会议,杂志文章,实务指引
doi：10.1016/j.medcli.2012.09.034
更新日期：2013-03-02 00:00:00
abstract：BACKGROUND:To study the clinical activity of systemic lupus erythematosus (SLE) in recipients of renal transplants (rT) performed by terminal renal failure (TRF) secondary to lupus nephritis. METHODS:The clinical evolution of 11 patients with SLE (ARA criteria) and TRF were evaluated with a descriptive character by th...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1994-02-26 00:00:00
