Abstract：
:Systemic vasculitis is a disease whose prognosis has improved considerably with steroid and immunosuppressive treatment, which points up the importance of early diagnosis. In elderly, diagnosis is made more difficult because the frequent onset in the form of a febrile syndrome with non-specific disturbances in general condition. In these patients it is not uncommon that a kidney involvement is what leads to diagnosis of the disease. Hematuria is almost a constant in vasculitis nephropathy. In their absence, acute renal failure in elderly is usually attributed to hemodynamic causes and the frequent presence of iatrogenic tubular factors. This is a report on the case of three elderly patients who presented a febrile syndrome with asthenia, anorexia and weight loss. The three cases progressed to acute renal failure with no disorders in urinary sediment. In two cases was a history of administration of gentamycin, indomethacin and iodated contrast. The clinical diagnosis was toxic and ischemic tubulopathy and, when dialysis became necessary, a renal biopsy was done which showed granulomatous vasculitis, intersticial nephritis and in two cases, necrotizing glomerulitis and crescent formation. Treatment with steroids and cyclophosphamide was started which improved general condition and renal function in one case. Early renal biopsy is advisable in senile patients with non specific systemic symptoms and progressive acute renal failure of unclear origin, even when hematuria is lacking. In this setting, the appearance of underdiagnosed renal vasculitis is possible, and consequent immunosuppressive treatment is a factor for consideration.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Poveda R,Díaz-Gallo C,Carrera M,González MT,Pac V,Vidaller A,Carreras L,Alsina Jkeywords:
subject
Has Abstractpub_date
1992-04-18 00:00:00pages
582-5issue
15eissn
0025-7753issn
1578-8989journal_volume
98pub_type
杂志文章相关文献
MEDICINA CLINICA文献大全abstract：:The health information system in Catalonia has experienced an important evolution but obtaining integrated data to evaluate the health services is still difficult. At the end of 2008 the basis of the information system of the "Center of Results" and a first set of indicators has been approved by the health system stak...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/S0025-7753(10)70006-3
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:To evaluate the adherence to the recommendations in clinical practice performed by the Therapeutic Positioning Report (TPR) of the Spanish Agency of Medicines and Sanitary Products about the treatment with oral anticoagulants in patients aged≥75 years old with nonvalvular atrial fibrillation (N...
journal_title：Medicina clinica
pub_type： 杂志文章,多中心研究
doi：10.1016/j.medcli.2017.07.025
更新日期：2018-07-13 00:00:00
abstract：BACKGROUND AND OBJECTIVE:White coat effect (WCE) (i.e., the difference between office blood pressure [OBP] and awake ambulatory blood pressure monitoring [ABPM]) may be present in hypertensive individuals. The relationship between occurrence of WCE and target organ damage (TOD) has not yet been assessed in true resista...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2012.04.031
更新日期：2013-01-05 00:00:00
abstract：BACKGROUND:Due to the double atherogenic and antifibrinolytic action of lipoprotein (a) (Lp [a]) and its predictive value of cardiovascular disease in hypercholesterolemic patients, we document in the present work the changes in Lp (a) levels of a patient with homozygous familial hypercholesterolemia after one year of ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1992-10-31 00:00:00
abstract：BACKGROUND:To evaluate the possible protector role of Lactobacillus against vaginal candidiasis. PATIENTS AND METHOD:In vitro studies performed to assess the capacity of 15 Lactobacillus strains to block the adhesion of two Candida albicans and one C. glabrata strain to vaginal epithelial cells and to inhibit the grow...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(01)72089-1
更新日期：2001-09-22 00:00:00
abstract：INTRODUCTION AND OBJECTIVE:To achieve control of rheumatoid arthritis (RA) it is necessary to be able to evaluate its activity. The American College of Rheumatology (ACR) recommends for this purpose indexes of activity that can be performed by the patient (PAS-II and RAPID-3) and IA including medical evaluation with la...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2017.02.025
更新日期：2017-10-11 00:00:00
abstract：BACKGROUND:Using the data available from the Cancer Registry of Zaragoza, the incidence of breast cancer in women from 1961 to 1985 was analyzed with future evolution being predicted up to the year 2000. METHODS:The age, period and birth cohort effects, in addition to the place of residence (capital/rest of province) ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1993-05-29 00:00:00
abstract：:Since uricosuria is an essential compensative factor in hyperuricemia, multiple factors exist which can influence on the uric acid excretion in the tubules. Normally, 90% of the uric acid filtered by the glomerulus is reabsorbed, and its active tubular secretion forms the greater part of the uric acid present in the u...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1980-02-10 00:00:00
abstract：FOUNDATIONS AND AIM:The aim of this study is to analyze the CHADS2 score as a marker of the risk of mortality in hypertensive patients, with and without the presence of atrial fibrillation. METHODS:We included 1,003 hypertensive patients≥65 years. Risk factors, and CHADS2 score were recorded among other factors, as we...
journal_title：Medicina clinica
pub_type： 杂志文章,多中心研究
doi：10.1016/j.medcli.2016.03.015
更新日期：2016-06-03 00:00:00
abstract：:Clinical trials and prospective observational registries are useful methods to gain knowledge of vascular disease. Because the design of clinical trials is mainly based on demonstrating the efficiency of therapeutic procedures, these studies cannot be widely generalized, especially in complex multifactorial diseases s...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/S0025-7753(09)71744-0
更新日期：2009-09-01 00:00:00
abstract：BACKGROUND:The polymerase chain reaction (PCR) constitutes important methodological progress for detecting the presence of viral nucleic acids when these are found in small quantities in serum or tissues. The aim of this study was the use of PCR to detect DNA of the hepatitis B virus (HBV) in patients with chronic HBsA...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1992-01-18 00:00:00
abstract：:Cephotaxime (HR 756) is a new cephalosporin antibiotic of wide spectrum and extraordinary activity, suitable for parenteral administration. It is highly resistant to the beta-lactamases of Gram negative bacilli, being thus especially active against microorganisms such as indole-positive Proteus, Serratia marcencens, a...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1980-11-25 00:00:00
abstract：:Since its inception in 2006, the Alliance for Patient Safety in Catalonia has played a major role in promoting and shaping a series of projects related to the strategy of the Ministry of Health, Social Services and Equality, for improving patient safety. One such project was the creation of functional units or committ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2014.07.011
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:In 2001 an outbreak of Legionnaires' diseases occurred in Murcia, Spain, with one of the lowest known rates of associated mortality. We describe the clinical data of a subgroup of patients, and present the results from molecular and virulence studies to correlate the lower mortality of the overall series wit...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2009.05.016
更新日期：2009-09-12 00:00:00
abstract：BACKGROUND:The sleep apnea syndrome (SAS) and high blood pressure (HBP) present multiple relations. Apnea culminates with an increase in arterial pressure, and a high percentage of apneic patients have HBP. It has also been reported that SAS is more frequent among hypertensive patients than among the general population...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1993-02-27 00:00:00
abstract：BACKGROUND:Primary pulmonary hypertension is a poorly understood disease with a difficult treatment. PATIENTS AND METHOD:Retrospective study of a series of 44 patients suffering from pulmonary hypertension who were studied in our center between 1992 and 2000. RESULTS:At diagnosis, 6 (13%) patients were classified as ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(02)72524-4
更新日期：2002-06-01 00:00:00
abstract：BACKGROUND:Myotonic dystrophy (DM) is an inherited autosomal dominant disorder. The molecular defect responsible for the disease is the expansion of a CTG triplet at the 3' end of the DM gene. We report the analysis of the gene expansion, its correlation with the clinical severity and with the phenomenon of anticipatio...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1993-03-13 00:00:00
abstract：:Alcohol causes different hematologic alterations on each of the three bone marrow cellular series. Its effect on the red series leads to the appearance of megaloblastic disturbances, erythroblastic vacuolization, iron metabolism abnormalities, and hemolytic syndromes. Megaloblastic disturbances may arise as a conseque...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1979-02-25 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The association of an exaggerated systolic blood pressure increase with exercise (EBPIE) with cardiovascular events remains controversial. Our aim was to determine the possible association of an EBPIE with survival and risk of serious cardiac events in patients with hypertension and known or su...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2016.09.016
更新日期：2017-01-20 00:00:00
abstract：:The case of a 19 year old patient with Takayasu arteritis with exclusive involvement of the abdominal aorta and without involvement of the renal arteries who presented severe arterial hypertension during the acute phase of the disease is referred. The administration of a dose of 20 mg of enalapril maleate was followed...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-22 00:00:00
abstract：:Amyotrophic neuralgia is an uncommon neuropathy characterized by severe unilateral shoulder pain. Isolated or concomitant involvement of other peripheral motor nerves depending on the brachial plexus such as phrenic or laryngeal nerves is unusual(1). Its etiology is unknown, yet several explanatory factors have been p...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2015.03.016
更新日期：2015-09-07 00:00:00
abstract：BACKGROUND:In this study the prescription of drugs in an outpatients geriatric population was evaluated in terms of age and body weight. METHODS:From a wide survey carried out on 500 geriatric outpatients, all the prescriptions corresponding to H-2 antagonists, digoxin, theophylline, bromazepam, diazepam, lorazepam an...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1992-03-07 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Our purpose was to provide information about static and dynamic balance posturographic disorders in elderly people with recurrent falls, and to compare the results with a healthy elderly group. PATIENTS AND METHOD:We included 95 subjects: 57 patients who fell (86% women; age, 78.1 years) and 3...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13071759
更新日期：2005-02-19 00:00:00
abstract：:Spinal cord compression is an infrequent event in patients with non-Hodgkin's lymphomas (NHL) and early diagnosis and therapy are required. The main clinical and histologic characteristics as well as the response to therapy in 10 NHL patients with spinal cord compression diagnosed at a single center in a 7-year period...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1997-09-27 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Fabry disease is a hereditary disorder. Clinical manifestations are multisystemic. The majority of the patients remain undiagnosed until late in life, when alterations could be irreversible. Early detection of cardiac symptoms is of major interest in Fabry's disease (FD) in order to gain acces...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2009.11.044
更新日期：2010-09-04 00:00:00
abstract：BACKGROUND AND OBJECTIVE:To study an outbreak of nosocomial colonisation/infection due to multidrug and carbapenem resistant A. baumannii (ABMDR-C). PATIENTS AND METHODS:Prospective study of patients with ABMDR-C colonisation/infection (January 2007-June 2008). Epidemiological and clinical variables and predictors of ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2010.01.033
更新日期：2010-09-18 00:00:00
abstract：BACKGROUND:Sentinel-node biopsy is meant to excise the first-echelon node from a primary tumor, which is the one that most probably harbors early metastases. PATIENTS AND METHODS:We report our results in 35 patients with breast cancer, using a radiotracer by peri-tumoral injection, pre-surgical scintigraphy and intrao...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1999-06-19 00:00:00
abstract：BACKGROUND AND OBJECTIVE:AIDS-related mortality has been classically associated with lowest socioeconomic groups. In Spain, the highly active antiretroviral therapy (HAART) is delivered without cost; therefore this treatment it should have reduced the great social inequalities in AIDS-mortality seen before the HAART er...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13115769
更新日期：2008-02-09 00:00:00
abstract：BACKGROUND:In the present study we evaluated the influence of the observer's status--physician or nurse--on blood pressure levels and the relationship among clinic blood pressure measurement with ambulatory blood pressure and left ventricle mass. PATIENTS AND METHODS:Cross sectional study performed in seven primary ca...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1999-12-11 00:00:00
abstract：BACKGROUND:Few reports have analysed the transmission of tuberculosis in rural areas with a low incidence of disease. PATIENTS AND METHOD:A population-based molecular epidemiological study of patients with tuberculosis, diagnosed by culture, was conducted in Segovia (Spain) between 1995 and 1999. Clinical, demographic...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(02)72484-6
更新日期：2002-05-11 00:00:00
