[Atherothrombosis: an excessively globalizing concept?].

Abstract:

:Clinical trials and prospective observational registries are useful methods to gain knowledge of vascular disease. Because the design of clinical trials is mainly based on demonstrating the efficiency of therapeutic procedures, these studies cannot be widely generalized, especially in complex multifactorial diseases such as vascular disease. The REACH registry overcomes many of these limitations, constituting the most numerous, extensive and powerful source of data on vascular diseases that is currently available. However, atherothrombosis is not the only mechanism of vascular disease, and awareness of this fact would improve diagnosis and allow more efficient treatment of these diseases.

journal_name

Med Clin (Barc)

journal_title

Medicina clinica

authors

Castillo J,Blanco M

doi

10.1016/S0025-7753(09)71744-0

subject

Has Abstract

pub_date

2009-09-01 00:00:00

pages

2-4

eissn

0025-7753

issn

1578-8989

pii

S0025-7753(09)71744-0

journal_volume

132 Suppl 2

pub_type

杂志文章
  • [Effects of simvastatin on acute-phase protein levels after cardiac surgery].

    abstract:BACKGROUND AND OBJECTIVE:There is contradictory evidence as to whether the pleiotropic effects of statins improve morbidity/mortality rates in coronary artery bypass grafting with extracorporeal circulation, as they reduce the protein plasma levels in the acute phase. PATIENTS AND METHOD:This randomized prospective st...

    journal_title:Medicina clinica

    pub_type: 杂志文章,随机对照试验

    doi:10.1157/13121102

    authors: Tamayo E,Alonso O,Alvarez FJ,Castrodeza J,Flórez S,di Stefano S

    更新日期:2008-05-31 00:00:00

  • [Consumption of sweets and snacks by a population of school children in the Autonomous Community of Madrid. The CAENPE Group].

    abstract:BACKGROUND:In our society advertising compaigns promote consumption of superfluous foods, such as sweets and snacks, displacing the intake of other basic nutrients. The aim of this study is to assess the intake of these foods by children, their relative contribution to overall macronutrient intake and their effects on ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: López del Val T,Estivariz CF,Martínez de Icaya P,Jaunsolo MA,del Olmo D,Vázquez Martínez C

    更新日期:1997-06-14 00:00:00

  • [Gallium-67 (Ga-67) scintigraphy in tuberculosis and Mycobacterium avium-M. intracellulare infections in patients with HIV infections].

    abstract:BACKGROUND:Diagnosis of mycobacterioses in HIV infected patients is sometimes difficult because of atypical findings. The aim of this study was to assess the utility of gallium scintigraphy in diagnosis of AIDS related mycobacterioses in patients with fever of unknown origin. PATIENTS AND METHODS:We retrospectively re...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: del Val Gómez Martínez M,Gallardo FG,March J,Laguna F

    更新日期:1998-05-02 00:00:00

  • Discrepancies between the use of MDRD-4 IDMS and CKD-EPI equations, instead of the Cockcroft-Gault equation, in the determination of the dosage of direct oral anticoagulants in patients with non-valvular atrial fibrillation.

    abstract:BACKGROUND AND OBJECTIVE:Direct oral anticoagulants (DOACs) require dose adjustment according to estimated clearance creatinine (eClCr) using the Cockcroft-Gault (CG) equation. There are discrepancies with the equations that estimate glomerular filtration rate (eGFR). We analyse how the use of the CKD-EPI and MDRD-4 ID...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2017.06.003

    authors: Pérez Cabeza AI,Chinchurreta Capote PA,González Correa JA,Ruiz Mateas F,Rosas Cervantes G,Rivas Ruiz F,Valle Alberca A,Bravo Marqués R

    更新日期:2018-02-09 00:00:00

  • [Limitations of insulin-dependent drugs in the treatment of type 2 diabetes mellitus].

    abstract::In this study, we review the efficacy and safety limitations of insulin-dependent oral antidiabetic agents. In terms of efficiency, the main drawback of metformin, sulfonylureas, gliptins and -to a lesser extent-glitazones is durability. No drug per se is able to maintain stable blood glucose control for years. Metfor...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/S0025-7753(13)70059-9

    authors: Valerón PF,de Pablos-Velasco PL

    更新日期:2013-09-01 00:00:00

  • [Clinical factors associated with bone mass loss previous cardiac transplantation].

    abstract:BACKGROUND:A high prevalence of osteoporosis has been described in patients before and after cardiac transplantation. But clinical factors involved in previous bone loss in this condition are not well known. The purpose has been to study bone mineral density (BMD) in patients subject to cardiac transplantation, analyzi...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(00)71430-8

    authors: García Delgado I,Gil-Fraguas L,Robles E,Martínez G,Hawkins F

    更新日期:2000-05-27 00:00:00

  • [Amebic liver abscess: review of 13 cases].

    abstract::Amebian hepatic abscess (AHA) is the most frequent extraintestinal localization of infection by Entamoeba histolytica. Despite being a disease mainly of tropical zones, it is currently also observed with higher frequency in Spain. Thirteen cases of AHA diagnosed in the authors' hospital over the last 11 years were ret...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: García-Forcada A,Sans M,Gascón J,Valls ME,Bru C,Corachán M

    更新日期:1995-10-28 00:00:00

  • [Factors associated with the development of atopy in young adults].

    abstract:BACKGROUND:To determine the risk factors for the development of atopy in Spanish young adults. SUBJECTS AND METHODS:Case-control study over prevalent cases. Carried out in general population between the ages of 20 to 44 years old. Spanish participants of the ECRHS, a random representative sample of Spanish young adult...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(00)71231-0

    authors: Cortès X,Soriano JB,Sunyer J,Martínez-Moratalla J,Muniozgoren N,Maldonado JA,Quirós R,Antó JM

    更新日期:2000-02-12 00:00:00

  • [Mediterranean diet improves low density lipoprotein susceptibility to oxidative modifications].

    abstract:UNLABELLED:Most experts, specially from Anglo-Saxon countries, recommend a low fat diet in order to prevent cardiovascular diseases. However, mortality rate by ischemic cardiopathy is low in Mediterranean countries, probably because of the consumption of a Mediterranean diet, with a high level of monounsaturated fats p...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(00)71561-2

    authors: López-Miranda J,Gómez P,Castro P,Marín C,Paz E,Bravo MD,Blanco J,Jiménez-Perepérez J,Fuentes F,Pérez-Jiménez F

    更新日期:2000-09-30 00:00:00

  • [Preventable adverse drug events in hospitalized patients].

    abstract:BACKGROUND AND OBJECTIVE:To determine the incidence of adverse drug events (ADE) in hospitalized patients, identify those that were potentially preventable, and asses the drug classes involved, the clinical symptoms and the type of medication errors that led to the preventable ADE. PATIENTS AND METHOD:An observational...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13083875

    authors: Otero-López MJ,Alonso-Hernández P,Maderuelo-Fernández JA,Garrido-Corro B,Domínguez-Gil A,Sánchez-Rodríguez A

    更新日期:2006-01-28 00:00:00

  • [Drug administration schedules in geriatric patients].

    abstract:BACKGROUND:In this study the prescription of drugs in an outpatients geriatric population was evaluated in terms of age and body weight. METHODS:From a wide survey carried out on 500 geriatric outpatients, all the prescriptions corresponding to H-2 antagonists, digoxin, theophylline, bromazepam, diazepam, lorazepam an...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Lucena González ML,García Domínguez MD,Andrade Bellido RJ,Hidalgo Sánchez R,Ramírez Torres JM,Sánchez de la Cuesta F

    更新日期:1992-03-07 00:00:00

  • [Prenatal diagnosis of hemoglobinopathies and thalassemias].

    abstract:BACKGROUND AND OBJECTIVE:Thalassemias are the most common single-gene disorders in the world population and the most important health problem in several countries. The best program of prevention of new births is prenatal diagnosis. Here we gather the experience from 1996 of the Spanish Group of Erythropathology related...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2008.09.012

    authors: Ropero P,González FA,Hernández A,Sánchez H,Cela E,Villegas A

    更新日期:2009-01-24 00:00:00

  • [Polycystic endodermal heterotopy of the atrioventricular node].

    abstract::We present the two first Spanish cases about the endodermic heterotopia of the atrioventricular node. This is an infrequent and probably congenital lesion, with a not well known histogenesis and associated with heart blocks and sudden death, which affects women in most cases. The first observation attaches a 55 years-...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:

    authors: Monzón Muñoz FJ,Aguilera Tapia B,Martínez-Peñuela Virseda JM,Oliva Aldamiz H

    更新日期:1995-02-25 00:00:00

  • [Significance of heterozygosity loss in the long arm of chromosome 5 (5q21) in small cell carcinoma of the lung].

    abstract:BACKGROUND:Loss of heterozygosity (LOH) at 5q21, where the APC/MCC genes reside, is one of the genetic alterations that characterizes lung cancer. The aim of this study was to analyse LOH frequency on chromosome 5q21 in patients with non-small cell lung cancer and its relationship with TNM staging and histological subt...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Sánchez Céspedes M,López Cabrerizo MP,Moreno I,Ariza A,Monzó M,Rosell R

    更新日期:1997-05-31 00:00:00

  • Metabolic risk factors in a cohort of young adults and their association with a body-mass index between 22 and 25 kg/m2.

    abstract:BACKGROUND AND OBJECTIVES:Although health risks associated to excessive body fat increase with small increases in body weight, measurement of body fat is usually grouped in very few categories. The aim of our study was to assess whether the risk for a combined end-point including the incidence of either hypertension an...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2009.02.016

    authors: Toledo E,Beunza JJ,Núñez-Córdoba JM,Bes-Rastrollo M,Basterra-Gortari FJ,Martínez-González MA

    更新日期:2009-05-09 00:00:00

  • [Meningiomas with disomy of chromosome 22: study of 9 cases].

    abstract:BACKGROUND:Cytogenetic studies of meningiomas suggest that loss of (or parts of) chromosome 22 is a primary event in the development of these tumors; later on, other chromosomal changes would occur in the caryotypes. All these secondary changes are observed mainly in cases with high clinical aggressivity. However, in a...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: López-Ginés C,Cerdá-Nicolás M,Pérez-Bacete M,Barcia-Salorio JL,Llombart-Bosch A

    更新日期:1998-11-21 00:00:00

  • [Study of deferoxamine in subcutaneous profusion treatment of iron overload in myelodysplastic syndromes].

    abstract:BACKGROUND AND OBJECTIVE:The progressive accumulation of iron in the organism contribute to one of the most important problems of morbidity and mortality in patients with myelodysplastic syndrome (MDS). We present an observational protocol, multicentre, open and non-aleatheorised, in patients diagnosed with MDS on tran...

    journal_title:Medicina clinica

    pub_type: 杂志文章,多中心研究

    doi:10.1157/13074739

    authors: González FA,Arrizabalaga B,Villegas A,Alonso D,Castro M,Remacha A,del Arco A,Martín Núñez G,Grupo Español de Eritropatología Española de Hematología y Hemoterapia.

    更新日期:2005-05-07 00:00:00

  • [Characteristics of patients with familial adenomatous polyposis in Spain. First results of the Spanish Registry of Familial Adenomatous Polyposis].

    abstract:BACKGROUND AND OBJECTIVES:Familial adenomatous polyposis is an inherited disorder characterized by the presence of multiple colorectal adenomas (more than 100 in the classic form and between 10 and 100 in the attenuated one), with a high risk of colorectal cancer development. To improve the diagnostic and therapeutic m...

    journal_title:Medicina clinica

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.medcli.2009.09.054

    authors: Alfaro I,Ocaña T,Castells A,Cordero C,Ponce M,Ramón Y Cajal T,Andreu M,Bujanda L,Herráiz M,Hervás Molina AJ,Fernández-Bañares F,Riestra-Menéndez S,Gargallo C,Ruiz A,Bustamante M,Blanco I,Martínez de Juan F,Registro Espa

    更新日期:2010-06-19 00:00:00

  • [Evaluation of the cost of an intensive medicine unit. Relationship between the cost and the severity of the disease].

    abstract:BACKGROUND:The evaluation of the costs of intensive care is a subject of interest at present, due to the high resources required by this area of health care services and the rhythm at which these costs increase. Such an evaluation has rarely been carried out in Spain. The aim of this study was to quantify the cost of m...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Llodra-Calvo JC,Vázquez-Mata G,Bueno-Cavanillas A,Delgado-Rodríguez M,Gálvez-Vargas R

    更新日期:1994-06-11 00:00:00

  • Analysis of biomedical Spanish articles retracted between 1970 and 2018.

    abstract:BACKGROUND AND OBJECTIVE:To analyse articles retracted due to irregularities by authors helps to determine the state of scientific integrity of a discipline or country. The Retraction Watch (RW) database is the largest worldwide database on retracted articles. The objective was to determine the reasons for and features...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2019.04.018

    authors: Dal-Ré R

    更新日期:2020-02-28 00:00:00

  • [Prognosis of patients admitted in a coronary care unit after resucitating from out-of-hospital sudden cardiac death].

    abstract:BACKGROUND AND OBJECTIVE:The aims of the present study were to analyze the prognosis after resuscitation from out-of-hospital sudden cardiac death in patients admitted to the coronary care unit, and to identify the predictor variables of morbi-mortality. PATIENTS AND METHOD:From November 1999 to January 2004 we analyz...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(06)72232-1

    authors: Vallès E,Martí V,Noguero M,Guindo J,Domínguez de Rozas JM

    更新日期:2006-09-02 00:00:00

  • [Correlative urinary excretion of sodium-uric acid in hyperuricemia (author's transl)].

    abstract::Since uricosuria is an essential compensative factor in hyperuricemia, multiple factors exist which can influence on the uric acid excretion in the tubules. Normally, 90% of the uric acid filtered by the glomerulus is reabsorbed, and its active tubular secretion forms the greater part of the uric acid present in the u...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Pérez Ortolá R,Picardo NG,Sánchez Palacios A

    更新日期:1980-02-10 00:00:00

  • [Health in all policies and intersectoriality in health promotion: the Public Health Interdepartmental Plan of Catalonia].

    abstract::In February 2014, the autonomous government in Catalonia, the Generalitat de Catalunya, approved the Catalan Public Health System Interdepartmental Plan (PINSAP, as per the Catalan acronym), responsible for the strategy in Catalonia for Health in All Policies, as recommended by the WHO and other international institut...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/S0025-7753(15)30036-1

    authors: Mateu i Serra A

    更新日期:2015-11-01 00:00:00

  • [Consumption patterns and the principal sources of lipids and fatty acids in the Spanish cohort of the European Prospective Investigation on Diet and Cancer (EPIC). The EPIC Group in Spain].

    abstract:BACKGROUND:To evaluate the fat consumption and main sources of specific fatty acids in adults from the south and north of Spain. SUBJECTS AND METHODS:Dietary data from 25,816 women and 15,635 men, aged 29-69 years, participants in the European Prospective Study on Cancer and Nutrition (EPIC) recruited in the north (As...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors:

    更新日期:1999-02-06 00:00:00

  • [Analysis of asthma control and quality of life in severe allergic asthmatics under treatment with anti-IgE, omalizumab].

    abstract:BACKGROUND AND OBJECTIVES:To evaluate anti-IgE (ie, omalizumab) efficacy on severe allergic asthma in order to achieve the efficacy of this treatment on severe allergic asthma progress by means of asthma control questionnaire (ACQ), asthma quality of life questionnaire (AQLQ) as well as pulmonary function (FEV1) and ph...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2009.07.011

    authors: Pacheco-Galván A,Hinojosa-Macías M,Hurtado-Barbudo B,González-Cervera J,Sueiro-Bendito A

    更新日期:2009-10-03 00:00:00

  • [Factors associated with mortality and gait impairment in elderly patients with hip fractures].

    abstract:BACKGROUND:Hip fractures are a major source of mortality and morbidity among the elderly. The aim of the present study is to try to identify predictors of death and of non-deambulation during the period of acute treatment. PATIENTS AND METHODS:Consecutive prospective study of 459 patients older than 65 years admitted ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Pagès E,Cuxart A,Iborra J,Olona M,Bermejo B

    更新日期:1998-05-23 00:00:00

  • [Smoking cessation after 12 months follow-up at a smoking cessation unit].

    abstract:BACKGROUND AND OBJECTIVE:To assess the cessation and relapse rates of smoking, and analyze the associated variables in a 12-month follow-up study at a smoking cessation unit. SUBJECTS AND METHOD:Patients from the Area de Salud 19 of the Conselleria de Sanitat of the Generalitat Valenciana, coming to a smoking cessatio...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13087715

    authors: Pascual-Lledó JF,De la Cruz-Amorós E,Bustamante-Navarro R,Buades-Sánchez MR,Contreras-Santos C,Castillo-Aguilar C

    更新日期:2006-04-29 00:00:00

  • [The usefulness of the teriparatide acetate (Parathar) infusion test in the diagnosis of pseudohypoparathyroidism].

    abstract::In pseudohypoparathyroidism there is a resistance to the action of the parathormone in its target organs. Patients with this disease show clinical and laboratory data of hypoparathyroidism with normal or high levels of parathormone. Three types of pseudohypoparathyroidism are known according to the site in which the d...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Rius F,Salinas I,Reverter JL,Pizarro E,Lucas A

    更新日期:1993-09-18 00:00:00

  • [Role of antiretroviral therapy in the reduction of the association between low educational level and AIDS-related mortality].

    abstract:BACKGROUND AND OBJECTIVE:AIDS-related mortality has been classically associated with lowest socioeconomic groups. In Spain, the highly active antiretroviral therapy (HAART) is delivered without cost; therefore this treatment it should have reduced the great social inequalities in AIDS-mortality seen before the HAART er...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13115769

    authors: Sánchez E,Regidor E,de la Fuente L,Luquero FJ,de Mateo S

    更新日期:2008-02-09 00:00:00

  • [Tumor necrosis factor-alpha in human immunodeficiency virus infection].

    abstract:BACKGROUND:The aim of the present was to determine the levels of the tumor necrosis factor (TNF)-alpha in patients with HIV infection to study the relationship with the concentration of triglycerides (TG), CD4 lymphocyte count and clinical diagnosis. METHODS:Seventy-eight HIV-infected patients (58 males, 20 females); ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Llobet P,Muga R,González JA,Abad E,Tor J,Rey-Joly C

    更新日期:1995-03-18 00:00:00