Abstract：
BACKGROUND AND OBJECTIVE:Clinical variability in myocardial infarction (MI) regarding age, comorbidities and atypical symptoms could determine gender differences in inhospital care. This study analyzes the magnitude and determinants of differences between men and women in early reperfusion therapy in people hospitalized after MI. PATIENTS AND METHOD:2,836 patients who arrived to hospital with MI were studied (IBERICA-Basque Country study). The relative risk (RR) of receiving early reperfusion for men versus women, adjusted by age, clinical characteristics, risk factors, and pre-hospital delay was estimated. The effect decomposition methodology and the log binomial regression were applied. RESULTS:29% of patients were women with a median age of 77 years. The RR of revascularization in men compared to women was different according to age. When factors such as hypertension diabetes, Killip III-IV at admission and atypical symptoms were taken into account, statistically significant differences between sexes were not detected at 45 years old (RR=0.91; 95% CI=0.77-1.07). However, for 64 years old and over, the RR of reperfusion was 1.24 (95% CI=1.05-1.47). Both the differences by sex and the sex-age interaction were no longer statistically significant after adjusting by pre-hospital delay. CONCLUSIONS:The delay to receive medical care in elderly women is responsible of gender differences in early reperfusion. It is necessary to analyze the reasons for treatment-seeking delay.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Aldasoro E,Calvo M,Esnaola S,Hurtado de Saracho I,Alonso E,Audicana C,Arós F,Lekuona I,Arteagoitia JM,Basterretxea M,Marrugat J,IBERICA-País Vasco Group.doi
10.1016/s0025-7753(07)72497-1subject
Has Abstractpub_date
2007-01-27 00:00:00pages
81-5issue
3eissn
0025-7753issn
1578-8989pii
S0025-7753(07)72497-1journal_volume
128pub_type
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