Abstract：
:Non-alcoholic fatty liver disease (NAFLD) consists of an excessive depositing of fat in the liver, which can end up by causing inflammation, fibrosis and also cirrhosis with the corresponding complications including liver cancer. NAFLD has become the most common liver disease worldwide. The incidence has increased in parallel with the obesity, diabetes and metabolic syndrome epidemic, thus resulting in becoming one of the main indications for liver transplant. The diagnosis has principally been through histology but with the development of non-invasive methods, these have helped in simplifying the management of these patients in clinical practice. The only therapeutic strategies currently available are focused on weight loss (lifestyle changes or bariatric surgery). There is still no approved pharmacological option for the treatment of NAFLD, however there are a number of molecular studies in advanced stages of development.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Augustin S,Graupera I,Caballeria J,en nombre del grupo de trabajo sobre «Hígado graso no alcohólico» de la Societat Catalana de Digestologia.doi
10.1016/j.medcli.2017.06.026subject
Has Abstractpub_date
2017-12-20 00:00:00pages
542-548issue
12eissn
0025-7753issn
1578-8989pii
S0025-7753(17)30512-2journal_volume
149pub_type
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