Abstract：
BACKGROUND AND OBJECTIVE:The aim of this study was to describe an outbreak of Q fever in a group of people (day care centre for mental-handicapped individuals) previously exposed to animals in a school-farm. PATIENTS AND METHOD:A retrospective cohort study among the 25 mental-handicapped individuals and the 30 workers of the centre was performed. The information about symptoms and signs and antecedents of exposition was obtained by an epidemiological survey and a clinical-epidemiological case definition was established. Serum samples from 29 people (5 mental-handicapped individuals and 24 workers) were processed for serology (Indirect Immunofluorescence against Coxiella burnetii). RESULTS:Twenty two cases of Q fever were detected. Ten were confirmed by serology (6 of them asymptomatic). More frequent symptoms were fever (100%), anorexia (81.3%), asthenia (68.8%) and non-productive cough (56.3%) among the 16 clinical cases. The risk of acute infection was 8.6 times higher in individuals of the centre that visited the school-farm (95% CI, 1.26-58.27). CONCLUSIONS:The investigation of the epidemiological antecedents allowed to detect and confirm a Q fever outbreak, to identify the probable source of exposition and to orientate the clinical and serological diagnosis.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
de los Ríos-Martín R,Sanz-Moreno JC,Martín-Martínez F,Tébar-Betegón MA,Cortés-García M,Escudero-Nieto Rdoi
10.1157/13087697subject
Has Abstractpub_date
2006-04-22 00:00:00pages
573-5issue
15eissn
0025-7753issn
1578-8989pii
S0025-7753(06)72020-6journal_volume
126pub_type
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