[Paradoxical correlation between plasma renin activity and hypotensive effect of beta-adrenergic blocking (author's transl)].

Abstract:

:A group of 39 patients has been divided in three categories according to their plasmatic renine activity and the correlation of the hipotensive answer to the Timolol Maleate (betadrenergic blocking). The control is more favourable in the normorreninemic than in the hiporreninemic patients and, paradoxically, even more than in the hyperreninemic. This unexpected answer is probably due to the lowest sodium intake of this last group. Hyperreninemia is more than a factor determining their basal hypertension: it is a regulation factor by hiposodic diet and probably, drug resistant. Nor quantitative neither qualitative correlation among the basal plasmatic renine activity and the hipotensive activity has been observed.

journal_name

Med Clin (Barc)

journal_title

Medicina clinica

authors

Ocón Pujadas J,Merello JI

subject

Has Abstract

pub_date

1980-09-10 00:00:00

pages

145-50

issue

4

eissn

0025-7753

issn

1578-8989

journal_volume

75

pub_type

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