Abstract:
:We performed a systematic review to assess the efficacy and safety of extracorporeal albumin dialysis systems in patients with liver failure. After screening 436 references, 10 controlled trials were detected. The analyzed interventions were MARS, Prometheus and Biologic-DT. Efficacy was proven by a reduction in bilirubin, creatinine and other toxic components after intervention. Clinical efficacy was measured in fewer studies, some of them showing an improvement in hepatic encephalopathy and survival. Intervention safety was assessed in a reduced number of studies and based on adverse events, being coagulation disorders in most cases. In summary, reviewed evidence showed that albumin dialysis based systems were able to reduce toxic parameters and improve clinical results in these settings. However, more studies are needed to further evaluate survival and adverse events based on standardised notification.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Lafuente S,Bertran MJ,Escorsell Adoi
10.1016/j.medcli.2010.01.032subject
Has Abstractpub_date
2011-04-23 00:00:00pages
484-7issue
11eissn
0025-7753issn
1578-8989pii
S0025-7753(10)00272-1journal_volume
136pub_type
杂志文章,评审相关文献
MEDICINA CLINICA文献大全abstract:BACKGROUND AND OBJECTIVE:Alcohol and drug dependent patients present a higher psychiatric comorbidity, which increases according to the number of drugs. Moreover, there are complications from the treatment and the prognosis is aggravated. We aimed to observe the differences regarding personality disorders (PD) and cogn...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13120771
更新日期:2008-05-17 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Infliximab is a chimeric monoclonal antibody that binds to tumor necrosis factor alpha and blocks the inflammatory response. The purpose of this study was to assess the effects of infliximab in patients with severe and refractory psoriasis. PATIENTS AND METHOD:Eleven patients with severe and r...
journal_title:Medicina clinica
pub_type: 临床试验,杂志文章
doi:10.1016/s0025-7753(04)74634-5
更新日期:2004-11-13 00:00:00
abstract:FOUNDATIONS AND AIM:The aim of this study is to analyze the CHADS2 score as a marker of the risk of mortality in hypertensive patients, with and without the presence of atrial fibrillation. METHODS:We included 1,003 hypertensive patients≥65 years. Risk factors, and CHADS2 score were recorded among other factors, as we...
journal_title:Medicina clinica
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medcli.2016.03.015
更新日期:2016-06-03 00:00:00
abstract:BACKGROUND:The aim of this study was the assessment of the scientific production and impact on academic and/or hospital promotion ob sabbatical leaves of medical staff from a University hospital. POPULATION AND METHODS:A matched case-control design was used. The Mantel-Haenszel odds ratio (ORMH) and its 95% confidence...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1998-10-03 00:00:00
abstract:BACKGROUND:Upon the detection of an excess number of cases of parotiditis in La Almolda (Zaragoza) a descriptive study of the epidemic was carried out with vaccination efficacy being quantified. METHODS:The definition and system of detection of the cases was established. To calculate the rate of infection the availabl...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1992-09-19 00:00:00
abstract:BACKGROUND:The polymerase chain reaction (PCR) constitutes important methodological progress for detecting the presence of viral nucleic acids when these are found in small quantities in serum or tissues. The aim of this study was the use of PCR to detect DNA of the hepatitis B virus (HBV) in patients with chronic HBsA...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1992-01-18 00:00:00
abstract::The serum levels of cholesterol bound to high density lipoproteins (HDL-C) were determined by the heparin-manganese chloride precipitation method in 306 subjects, 182 male with ages ranging from 11 to 81 years, and 124 female with ages ranging from 7 to 78 years. Twenty six subjects belonged to a lacto-vegetarian comm...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1981-03-25 00:00:00
abstract::To evaluate the clinical and microbiological features of infective endocarditis in patients with cirrhosis we compared 18 episodes of endocarditis in these patients with a control group of patients without liver disease. In 61% of patients with cirrhosis the origin of infection was unknown. Four patients developed end...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1989-11-11 00:00:00
abstract:BACKGROUND:There is no detailed information on the scientific production in biomedicine from the perspective of the centers which make up the National Health Care System. Nor has any analysis on productivity by specialties compared with that of other countries of the European Community (EC) been carried out. METHODS:T...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1993-12-04 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The smoke fume, principal factor in the development of lung cancer, causes the expression of certain cytokines, including interleukin 4, 6, 8 and 10, which may act by inhibiting apoptosis and interfere cellular repair mechanisms and angiogenesis. To determine the possible relationship between g...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2013.07.034
更新日期:2014-08-04 00:00:00
abstract::The incidence and clinical course of urinary tract infections in postmenopausal diabetic patients in comparison to non-diabetic women have been evaluated. All cases with former history of urinary instrumentation or underlying conditions favoring urinary infections were rejected. Urinary tract infection was present in ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-10-10 00:00:00
abstract::Usher syndrome includes hereditary pathologies characterized by bilateral sensorineural deafness and visual impairment due to retinitis pigmentosa. Clinically, there are three distinct subtypes referred to as USH1, USH2, and USH3. Each subtype is genetically heterogeneous. Eleven different genes are implicated in the ...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1157/13079387
更新日期:2005-10-01 00:00:00
abstract::Pulmonary complications in HIV-infected patients are at present a first-rate problem. They are the main cause of hospital admission of these patients in our country. Most HIV-patients have a pulmonary complication during the evolution of the infection. The main etiologic diagnosis is bacterial pneumonia, especially pn...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1157/13080461
更新日期:2005-10-22 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In the last years, a study is being conducted about exposure to asbestos among shipyards workers in order to know the diagnosis of the diseases associated with the exposure. Our goal was to know the asbestos pulmonary contents in this population. MATERIAL AND METHODS:We obtained autopsy pulmon...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2012.01.023
更新日期:2013-02-16 00:00:00
abstract::The follow-up of the Mediterranean Diet (MD) has been associated with lower mortality and morbidity from cardiovascular diseases. However, it is important to evaluate the scientific evidence provided by published articles. Therefore, in order to analyze the literature on the overall effects of MD on intermediate and f...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/j.medcli.2009.01.033
更新日期:2010-01-23 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Fabry disease is a hereditary disorder. Clinical manifestations are multisystemic. The majority of the patients remain undiagnosed until late in life, when alterations could be irreversible. Early detection of cardiac symptoms is of major interest in Fabry's disease (FD) in order to gain acces...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2009.11.044
更新日期:2010-09-04 00:00:00
abstract:BACKGROUND:It is estimated that 5-10% of breast cancers have an hereditary origin, germline mutations of BRCA1 and BRCA2 genes causing a predisposition. In the present study we analyzed BRCA1 and BRCA2 mutations in moderate to high risk breast cancer patients in order to find out the types and frequency of these mutati...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(02)73450-7
更新日期:2002-10-12 00:00:00
abstract:INTRODUCTION:Neurosarcoidosis is a rare complication of sarcoidosis. There are small series on the condition and very few from Spain. We conducted a retrospective study of neurosarcoidosis in Virgen de la Victoria Hospital over the last 10 years. PATIENTS AND METHOD:the medical records of patients diagnosed with sarco...
journal_title:Medicina clinica
pub_type:
doi:10.1016/j.medcli.2020.04.027
更新日期:2020-10-09 00:00:00
abstract:BACKGROUND:It is not settled whether aspirin (ASA) failure may be predicted in stroke and transient ischemic attack (TIA) patients. The risk of ASA failure may be predicted by analyzing the epidemiological traits of patients with stroke or TIA. PATIENTS AND METHODS:We evaluated retrospectively 695 stroke or TIA patien...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1997-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:There is a bidirectional association between neoplasia and venous thromboembolism (VTE). However, whether this association has an impact in tumor recurrence is unknown. The aim of the study is to assess the incidence of cancer recurrence after diagnosis of VTE and determine if VTE could be a ma...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2009.04.054
更新日期:2009-10-17 00:00:00
abstract::We analyzed the tissue oxygen extraction in 25 patients with acute respiratory failure. Fourteen met the clinical criteria for the adult respiratory distress syndrome (ARDS). The 11 remaining patients had acute respiratory failure with causes different from ARDS. In all cases the changes in the oxygen extraction ratio...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1991-01-26 00:00:00
abstract::Negative-pressure wound therapy (NPWT) is used to promote wound healing by using suction to drain excess fluid from wounds. A systematic literature review was undertaken to assess the effectiveness, safety and cost-effectiveness of NPWT for the treatment of chronic wounds. Medline, Embase, CENTRAL, CINAHL and the Coch...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/j.medcli.2010.06.010
更新日期:2011-09-17 00:00:00
abstract:BACKGROUND:The aim of the present study was to obtain information about tuberculosis (TB) in our area that might contribute to assess the status in Spain. METHODS:A meticulous case finding was carried out during 1988 in all the hospitals of the Gran Canaria island. RESULTS:214 cases were found (rate 32.2) and 77% wer...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1991-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:White coat effect (WCE) (i.e., the difference between office blood pressure [OBP] and awake ambulatory blood pressure monitoring [ABPM]) may be present in hypertensive individuals. The relationship between occurrence of WCE and target organ damage (TOD) has not yet been assessed in true resista...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2012.04.031
更新日期:2013-01-05 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Diffuse idiopathic skeletal hyperostosis (DISH) and abdominal aortic calcification (AAC) are related to an increased cardiovascular risk. The aim of this study was to analyse a possible relationship between both entities and also the association between metabolic disorders and DISH. PATIENTS A...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2017.01.030
更新日期:2017-09-08 00:00:00
abstract::Bipolar disorder is a chronic and recurrent mood disorder, which may severely impact on the patient's global functioning. It has been estimated that approximately 1.6% of the population is affected. A long delay in diagnosis and an excessive disparity in the treatment of these patients have been detected. Within the Q...
journal_title:Medicina clinica
pub_type: 杂志文章,实务指引
doi:10.1016/j.medcli.2013.05.023
更新日期:2013-10-05 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Anxiety and depression are common among medical inpatients. While their relation to the severity of illness is often discussed, the feeling of such severity by the patient and his/her prospects of improvement can be influenced by anxiety and depression. PATIENTS AND METHOD:Patients admitted in...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:2003-03-22 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Primary biliary cirrhosis (PBC) is associated to any systemic autoimmune disease (SAD), in particular systemic sclerosis (SSc). To investigate the prevalence of SAD in a cohort of patients with PBC, specifically the prevalence of SSc and its clinical subtypes, and determining the clinical and ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2015.02.026
更新日期:2016-01-01 00:00:00
abstract::A 75 year-old male presented with hyperkalemia unexplained by a moderate renal insufficiency, low basal levels of aldosterone and renin with a subnormal response to walking and saline depletion, and normal glucocorticoid function. The hyperkalemia was corrected by fluorocortisone administration. The concept of hypoald...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-11-10 00:00:00
abstract:BACKGROUND:Candida albicans is distributed in at least two serological groups (A and B) depending on its antigenic structure. These characteristics have been used to investigate the epidemiology of candidiasis. No information is available in this country about the distribution of these serotypes in a general population...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1991-06-01 00:00:00