[Artificial liver support. Literature review].

Abstract:

:We performed a systematic review to assess the efficacy and safety of extracorporeal albumin dialysis systems in patients with liver failure. After screening 436 references, 10 controlled trials were detected. The analyzed interventions were MARS, Prometheus and Biologic-DT. Efficacy was proven by a reduction in bilirubin, creatinine and other toxic components after intervention. Clinical efficacy was measured in fewer studies, some of them showing an improvement in hepatic encephalopathy and survival. Intervention safety was assessed in a reduced number of studies and based on adverse events, being coagulation disorders in most cases. In summary, reviewed evidence showed that albumin dialysis based systems were able to reduce toxic parameters and improve clinical results in these settings. However, more studies are needed to further evaluate survival and adverse events based on standardised notification.

journal_name

Med Clin (Barc)

journal_title

Medicina clinica

authors

Lafuente S,Bertran MJ,Escorsell A

doi

10.1016/j.medcli.2010.01.032

subject

Has Abstract

pub_date

2011-04-23 00:00:00

pages

484-7

issue

11

eissn

0025-7753

issn

1578-8989

pii

S0025-7753(10)00272-1

journal_volume

136

pub_type

杂志文章,评审
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  • [Use of the CHADS2 score as a predictor of the risk of mortality in hypertensive patients. The FAPRES study].

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    doi:

    authors: Asenjo MA,Vernet E,Trilla A,Rodés J,Terés J,Grau J

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    doi:

    authors: Guimbao Bescós J,Moreno Marín MP,Gutiérrez Colás V,Pac Sá MR,Arribas Monzón F

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  • [Detection of hepatitis B virus DNA in serum by gene amplification in patients with chronic hepatitis B and in patients chronic hepatitis C].

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    doi:

    authors: Jáuregui JI,Civeira MP,Serrano M,Camps J,Castilla A,Riezu-Boj JI,Prieto J

    更新日期:1992-01-18 00:00:00

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    doi:

    authors: Masdeu S,Nubiola AR,Masana L,Ras MR,Chacón P,Ramos F,Rubiés-Prat J

    更新日期:1981-03-25 00:00:00

  • [Infectious endocarditis in patients with liver cirrhosis].

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    pub_type: 杂志文章

    doi:

    authors: Otones J,Fernández Clúa MA,Castrillo JM,Fernández Guerrero ML

    更新日期:1989-11-11 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Camí J,Fernández MT,Gómez Caridad I

    更新日期:1993-12-04 00:00:00

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    authors: Jiménez-Massa AE,Alonso-Sardón M,Menacho-Miguel JA,Mirón-Canelo JA,González-Sarmiento R

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  • [Urinary tract infection in postmenopausal diabetic women. Clinical survey of hospital and nonhospital populations (author's transl)].

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    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Torres Martí A,Jordá R,Vernet M,Cano JF,Coll J,Vivancos J,Balcells A

    更新日期:1980-10-10 00:00:00

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    abstract::Usher syndrome includes hereditary pathologies characterized by bilateral sensorineural deafness and visual impairment due to retinitis pigmentosa. Clinically, there are three distinct subtypes referred to as USH1, USH2, and USH3. Each subtype is genetically heterogeneous. Eleven different genes are implicated in the ...

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    pub_type: 杂志文章,评审

    doi:10.1157/13079387

    authors: Nájera C,Beneyto M,Millán JM

    更新日期:2005-10-01 00:00:00

  • [Infectious pulmonary complications in HIV-infected patients in the high by active antiretroviral therapy era in Spain].

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    authors: Benito Hernández N,Moreno Camacho A,Gatell Artigas JM

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    pub_type: 杂志文章,评审

    doi:10.1016/j.medcli.2009.01.033

    authors: Sotos-Prieto M,Zulet MA,Corella D

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  • [Role of cardiac magnetic resonance in cardiac involvement of Fabry disease].

    abstract:BACKGROUND AND OBJECTIVES:Fabry disease is a hereditary disorder. Clinical manifestations are multisystemic. The majority of the patients remain undiagnosed until late in life, when alterations could be irreversible. Early detection of cardiac symptoms is of major interest in Fabry's disease (FD) in order to gain acces...

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    authors: Serra VM,Barba MA,Torrá R,Pérez De Isla L,López M,Calli A,Feltes G,Torras J,Valverde V,Zamorano JL

    更新日期:2010-09-04 00:00:00

  • [Molecular study of the BRCA1 and BRCA2 genes in 153 breast cancer families from Castilla and León (Spain): new nine unclassified variants identified].

    abstract:BACKGROUND:It is estimated that 5-10% of breast cancers have an hereditary origin, germline mutations of BRCA1 and BRCA2 genes causing a predisposition. In the present study we analyzed BRCA1 and BRCA2 mutations in moderate to high risk breast cancer patients in order to find out the types and frequency of these mutati...

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    pub_type: 杂志文章

    doi:10.1016/s0025-7753(02)73450-7

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    abstract:INTRODUCTION:Neurosarcoidosis is a rare complication of sarcoidosis. There are small series on the condition and very few from Spain. We conducted a retrospective study of neurosarcoidosis in Virgen de la Victoria Hospital over the last 10 years. PATIENTS AND METHOD:the medical records of patients diagnosed with sarco...

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    pub_type:

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    authors: Carazo Barrios L,Abarca Costalago M,Hidalgo Conde A,Arnedo Díez de Los Ríos R,García Portales R,García Martín G

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  • [Factors associated to aspirin failure for secondary stroke prevention].

    abstract:BACKGROUND:It is not settled whether aspirin (ASA) failure may be predicted in stroke and transient ischemic attack (TIA) patients. The risk of ASA failure may be predicted by analyzing the epidemiological traits of patients with stroke or TIA. PATIENTS AND METHODS:We evaluated retrospectively 695 stroke or TIA patien...

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    doi:

    authors: Chamorro A,Blanc R,Ascaso C,Saiz A,Vila N

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  • [Deep venous thrombosis as a marker of tumor recurrence].

    abstract:BACKGROUND AND OBJECTIVE:There is a bidirectional association between neoplasia and venous thromboembolism (VTE). However, whether this association has an impact in tumor recurrence is unknown. The aim of the study is to assess the incidence of cancer recurrence after diagnosis of VTE and determine if VTE could be a ma...

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    pub_type: 杂志文章

    doi:10.1016/j.medcli.2009.04.054

    authors: Blanch Alerany M,Calvo Campos M,Romera Villegas A,Pérez-Piqueras Gómez A,Riera Batalla S,Cairols Castellote MA

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  • [Changes in tissue oxygen extraction in patients with acute respiratory insufficiency].

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    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Renes Carreño E,Lorente Balanza JA,Gómez Aguinaga MA,Landín Limeses L,Rodríguez Díaz R,Liste Jiménez D

    更新日期:1991-01-26 00:00:00

  • [Effectiveness, safety and cost-effectiveness of the negative pressure wound therapy on the treatment of chronic wounds: a systematic review].

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    pub_type: 杂志文章,评审

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    authors: Trujillo-Martín M,García-Pérez L,Serrano-Aguilar P

    更新日期:2011-09-17 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Caminero JA,Díaz F,Rodríguez de Castro F,Alonso JL,Daryanany RD,Carrillo T,Cabrera P

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    doi:10.1016/j.medcli.2012.04.031

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  • [Clinical practice guideline on bipolar disorder: drug and psychosocial therapy. Asociación Española de Neuropsiquiatría].

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    pub_type: 杂志文章,实务指引

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    authors: Bravo MF,Lahera G,Lalucat L,Fernández-Liria A,en representación del Grupo Elaborador de la Guía.,Asociación Española de Neuropsiquiatría.

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    doi:

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    pub_type: 杂志文章

    doi:

    authors: Cuervas-Mons V,Moya Mir MS,Martín Martín F,Barbadillo García de Velasco R,Sánchez Miró I,Martín Jiménez T,Lorenz Pérez P

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    abstract:BACKGROUND:Candida albicans is distributed in at least two serological groups (A and B) depending on its antigenic structure. These characteristics have been used to investigate the epidemiology of candidiasis. No information is available in this country about the distribution of these serotypes in a general population...

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    pub_type: 杂志文章

    doi:

    authors: Torres-Rodríguez JM,Nicolás MC,Madrenys N,Gallach C

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