Diagnosis and treatment of hepatocellular carcinoma. Update of the consensus document of the AEEH, AEC, SEOM, SERAM, SERVEI, and SETH.

Abstract:

:Hepatocellular carcinoma (HCC) is the most common primary liver neoplasm and one of the most common causes of death in patients with cirrhosis of the liver. In parallel, with recognition of the clinical relevance of this cancer, major new developments have recently appeared in its diagnosis, prognostic assessment and in particular, in its treatment. Therefore, the Spanish Association for the Study of the Liver (AEEH) has driven the need to update the clinical practice guidelines, once again inviting all the societies involved in the diagnosis and treatment of this disease to participate in the drafting and approval of the document: Spanish Society for Liver Transplantation (SETH), Spanish Society of Diagnostic Radiology (SERAM), Spanish Society of Vascular and Interventional Radiology (SERVEI), Spanish Association of Surgeons (AEC) and Spanish Society of Medical Oncology (SEOM). The clinical practice guidelines published in 2016 and accepted as National Health System Clinical Practice Guidelines were taken as the reference documents, incorporating the most important recent advances. The scientific evidence and the strength of the recommendation is based on the GRADE system.

journal_name

Med Clin (Barc)

journal_title

Medicina clinica

authors

Reig M,Forner A,Ávila MA,Ayuso C,Mínguez B,Varela M,Bilbao I,Bilbao JI,Burrel M,Bustamante J,Ferrer J,Gómez MÁ,Llovet JM,De la Mata M,Matilla A,Pardo F,Pastrana MA,Rodríguez-Perálvarez M,Tabernero J,Urbano J,Vera

doi

10.1016/j.medcli.2020.09.022

subject

Has Abstract

pub_date

2021-01-15 00:00:00

eissn

0025-7753

issn

1578-8989

pii

S0025-7753(20)30769-7

pub_type

实务指引
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    abstract::The authors report a case of hepatorenal polycystic disease discovered in the course of a routine physical examination. The patient was asymptomatic and the progression of the disease was extremely low. The existence of the disorder, however, was confirmed in the autopsy. Although hepatorenal polycystic disease is a r...

    journal_title:Medicina clinica

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    authors: Bofill D,Cabrer B,Grau A,Llebot J,Montis R,Vivancos J,Balcells A

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  • [Characteristics of hypertensive cardiomyopathy in a population of hypertensive patients never treated].

    abstract:BACKGROUND AND OBJECTIVE:Although impaired diastolic function is frequently found in systemic hypertension, the diagnosis of hypertensive heart disease (HHD) is based on the demonstration of left ventricular (LV) growth. The aim of the current work was to investigate the potential interactions between diastolic functio...

    journal_title:Medicina clinica

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    更新日期:2005-09-17 00:00:00

  • [Usefulness of the basic exploration of the upper airways and neighbor structures in patients with adult obstructive sleep apnea-hypopnea syndrome].

    abstract::Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a prevalent disease in the general population, associated with an increase in the cardiovascular morbimortality. A basic and/or standardized otolaryngologic exploration could help us to detect the structural abnormalities that alter the upper airway collapsibility a...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

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    authors: Ferré A,Vila J,Arcalís N

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  • [Hyperimmunoglobulinemia D and periodic fever syndrome. A phenotypical analysis of a Spanish family].

    abstract:BACKGROUND:Hyperimmunoglobulinemia D and periodic fever syndrome (HIDS) is a disorder diagnosed with low frequency, that produces a very prolonged and recurrent fever with other symptoms and analytical markers of inflammation. Its origin seems to be hereditary with a recessive autosomic pattern, but its pathogenic mech...

    journal_title:Medicina clinica

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    authors: García-Díaz JD,Alvarez-Blanco MJ

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  • Analysis of biomedical Spanish articles retracted between 1970 and 2018.

    abstract:BACKGROUND AND OBJECTIVE:To analyse articles retracted due to irregularities by authors helps to determine the state of scientific integrity of a discipline or country. The Retraction Watch (RW) database is the largest worldwide database on retracted articles. The objective was to determine the reasons for and features...

    journal_title:Medicina clinica

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    更新日期:2020-02-28 00:00:00

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    abstract:BACKGROUND:It is not settled whether aspirin (ASA) failure may be predicted in stroke and transient ischemic attack (TIA) patients. The risk of ASA failure may be predicted by analyzing the epidemiological traits of patients with stroke or TIA. PATIENTS AND METHODS:We evaluated retrospectively 695 stroke or TIA patien...

    journal_title:Medicina clinica

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    abstract:BACKGROUND:To study the clinical activity of systemic lupus erythematosus (SLE) in recipients of renal transplants (rT) performed by terminal renal failure (TRF) secondary to lupus nephritis. METHODS:The clinical evolution of 11 patients with SLE (ARA criteria) and TRF were evaluated with a descriptive character by th...

    journal_title:Medicina clinica

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    更新日期:1994-02-26 00:00:00

  • [Transforming growth factor beta (TGF-beta) in Gaucher's disease. Preliminary results in a group of patients and their carrier and non-carrier relatives].

    abstract:BACKGROUND:The poor phenotype/genotype correlation in Gaucher's disease makes difficult therapy-decision-making and prevention of complications. Gaucher's cells and tissue fibrosis are the earliest findings of the disease. Transforming growth factor ss (TGF-beta1) is the key cytokine involved in the regulation of tissu...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(00)71637-x

    authors: Pérez Calvo JI,Iñigo Gil P,Giraldo Castellano P,Torralba Cabeza MA,Civeira F,Lario García S,Pocoví M

    更新日期:2000-11-11 00:00:00

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    abstract::We present the two first Spanish cases about the endodermic heterotopia of the atrioventricular node. This is an infrequent and probably congenital lesion, with a not well known histogenesis and associated with heart blocks and sudden death, which affects women in most cases. The first observation attaches a 55 years-...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

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    更新日期:1995-02-25 00:00:00

  • [Clinical and methodological considerations in the quantification of estrogen and progesterone receptors using monoclonal antibodies in breast cancer].

    abstract:BACKGROUND:The aim of the present study was to provide information on several clinical and methodological aspects of the measurement of the contents of estrogen (ER) and progesterone (PgR) receptors in breast tumoral tissue using monoclonal antibodies. METHODS:The contents of ER and PgR were measured in 94 tumor speci...

    journal_title:Medicina clinica

    pub_type: 杂志文章

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    authors: Navarro MA,Huguet J,Valero J,Samaniego JM,Rosel P,Sirvent JJ

    更新日期:1991-06-08 00:00:00

  • [Cross-cultural validation of Antonovsky's Sense of Coherence Scale (OLQ-13) in Spanish elders aged 70 years or more].

    abstract:BACKGROUND AND OBJECTIVE:Sense of Coherence (SOC) is a construct relating to coping strategies in the face of traumatic events. SOC is defined as a personal disposition towards perceiving life experiences as understandable, manageable and meaningful. The construct has shown itself to be a predictor of self-reported and...

    journal_title:Medicina clinica

    pub_type: 杂志文章

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    authors: Virués-Ortega J,Martínez-Martín P,Del Barrio JL,Lozano LM,Grupo Español de Estudios Epidemiológicos sobre Envejecimiento.

    更新日期:2007-04-07 00:00:00

  • [Genetic and environmental contributions to body mass index in a Spanish adolescent twin sample].

    abstract:BACKGROUND AND OBJECTIVE:Twin and family studies support large genetic influences on variability in body mass index (BMI), with heritability estimates ranging from 47% to over 90%. Our objective was to study the relative contributions of genetics and environment to BMI, evaluating sex differences, in an adolescent twin...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2014.05.039

    authors: Iranzo-Tatay C,Gimeno-Clemente N,Livianos-Aldana L,Rojo-Moreno L

    更新日期:2015-08-21 00:00:00

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    abstract::The case of a 31 year-old intravenous drug addict female patient with infection by the human immunodeficiency virus who had recurrent cardiac tamponade and who was diagnosed by pericardic biopsy as Kaposi's sarcoma is reported. The patient demonstrated involvement by cutaneous, mucosal, lymph node and probably pleurop...

    journal_title:Medicina clinica

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    authors: Just M,Raventós A,Romeu J,Larrousse E,Santos J,Ojanguren I

    更新日期:1994-04-09 00:00:00

  • [Lung rounded atelectasis. A benign lesion due to asbestos].

    abstract:BACKGROUND AND OBJECTIVE:Rounded atelectasis (RA) is an unusual form of pulmonary lesion often confounded with pulmonary neoplasia. We studied the main diagnostic and evolutive characteristics of a series of patients diagnosed with RA. PATIENTS AND METHOD:Twenty patients diagnosed of RA in a tertiary hospital in Catal...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13072036

    authors: Gispert P,Andreu J,Ferrer M,Ferrer J

    更新日期:2005-02-26 00:00:00

  • [Chronic ischaemic heart disease in the elderly].

    abstract::It is the aim of this manuscript to take into account the peculiarities and specific characteristics of elderly patients with chronic ischaemic heart disease from a multidisciplinary perspective, with the participation of the Spanish Society of Cardiology (sections of Geriatric Cardiology and Ischaemic Heart Disease/A...

    journal_title:Medicina clinica

    pub_type: 共识发展会议,杂志文章,实务指引

    doi:10.1016/j.medcli.2016.01.014

    authors: Martínez-Sellés M,Gómez Huelgas R,Abu-Assi E,Calderón A,Vidán MT

    更新日期:2016-04-15 00:00:00

  • [Glycosylated hemoglobin as a hyperuricemia risk marker in general population].

    abstract:BACKGROUND AND OBJECTIVES:To evaluate the association between high levels of glycemia and low serum uric acid levels in two independent population-based samples. PATIENTS AND METHODS:The first sample was taken from the Pizarra Study, a population-based prospective study of 1.226 persons classified according to their g...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2010.09.044

    authors: García-Escobar E,Pérez-Valero V,Maseda D,Valdés S,Yahyaoui R,Hernando V,Vicioso MI,Ruiz de Adana MS,Espinosa Rodrı'guez M,Rojo-Martínez G,Soriguer F

    更新日期:2011-04-23 00:00:00

  • [Levodopa-induced psychosis in patients with idiopathic Parkinson disease].

    abstract:BACKGROUND:To identify which clinical factors can modify the probability of the appearance of the psychotic syndromes in patients with idiopathic Parkinson's disease treated with levodopa. PATIENTS AND METHODS:214 patients were retrospectively studied to evaluate the appearance of hallucinosis, delusions or mental con...

    journal_title:Medicina clinica

    pub_type: 杂志文章

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    authors: García-Escrig M,Bermejo Pareja F,Fernández Ponsatí JT

    更新日期:1999-02-27 00:00:00

  • [LDL concentration and particle size after treatment with rosiglitazone in patients with diabetes mellitus type 2].

    abstract:BACKGROUND AND OBJECTIVE:The effects of rosiglitazone on the lipid profile are controversial, with related increases in the concentration of total and LDL cholesterol. Our objective is to evaluate the evolution of the concentration and size of LDL particles in a group of patients with type 2 diabetes mellitus taking ro...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2008.05.001

    authors: Albaladejo Otón MD,Calle Luna JG,Granero Fernández E,Hernández Martínez AM,Parra Pallarés S,Martínez Hernández P

    更新日期:2009-01-31 00:00:00

  • [Hereditary angioedema. Control and treatment in 7 cases].

    abstract::Hereditary angioedema (HAE) is due to a deficit of the C1 inhibitor (C1 INH) of a dominant autosomic inheritance. Seven patients are presented from a family with HAE, four of whom with poor prognosis due to the frequency and site of the angioedema. Prophylaxis was obtained with long-term danazol since antifibrinolytic...

    journal_title:Medicina clinica

    pub_type: 杂志文章

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    authors: Marqués L,Dordal T,Baltasar M,Guspi R,Nogueiras C,Cadahia A

    更新日期:1992-03-14 00:00:00

  • [Mortality attributable to tobacco consumption in Galicia (Spain): 1980-2007].

    abstract:UNLABELLED:BACKGROUND AND OJECTIVE: Tobacco attributable mortality offers a complementary view to smoking prevalence, giving an estimate of its impact at population level. The purpose of this study is to measure the impact, using mortality figures, of tobacco consumption in the Galician population over 34 years from 19...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2010.10.009

    authors: Pérez-Ríos M,Santiago-Pérez MI,Cerdeira-Caramés S,Alonso B,Seoane B,Malvar-Pintos A,Hervada-Vidal X

    更新日期:2011-09-10 00:00:00

  • [A study of bone mineral density in adult patients with cystic fibrosis].

    abstract:BACKGROUND AND OBJECTIVE:Due to recent medical advances, patients with cystic fibrosis (CF) can expect longer survival rates and, as a result, face previously unreported complications such as osteoporosis. Our goal was to determine the mineral bone density in young adult patients with CF attended in the adult CF Unit, ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(04)74420-6

    authors: Girón RM,Sánchez Moliní P,Almonacid C,Jiménez I,Rodríguez Salvanés F,García Vadillo A,Quintana ML,Hurtado J,Ancochea J

    更新日期:2004-06-19 00:00:00

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    abstract:BACKGROUND:Increasing attention has been given to the care to elderly patients in emergency departments (ED). Moreover, few data are available about final phase of the process, that is hospital admission from ED. This study was conducted to establish appropriateness, reasons and social factors related to hospital admis...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: González-Montalvo JI,Baztán JJ,Rodríguez-Mañas L,San Cristóbal E,Gato A,Ballesteros P,Salgado A

    更新日期:1994-10-15 00:00:00

  • [Rapidly progressive glomerular disease treated with plasmapheresis (author's transl)].

    abstract::A case of rapidly progressive glomerular disease with 100% of epithelial crescents completely enveloping each glomerulus, prolonged anuria and renal failure requiring dialysis. There were no indications of either streptococcal etiology or systemic disease. Improvement in renal function in response to plasmapheresis an...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Praga M,Mijares R,Elósegui A,de los Mozos J,Ochoa de Olza M,Cortabitarte N,López de Novales E

    更新日期:1981-06-10 00:00:00

  • [antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease].

    abstract:BACKGROUND:The aim of the present study was to determine the prevalence and diagnostic usefulness of antineutrophil cytoplasmic antibodies (ANCA) in a Spanish population of patients with inflammatory bowel disease from the province of Tarragona. PATIENTS AND METHODS:One hundred and fifty-six sera obtained from 116 pat...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Papo M,Quer JC,Pastor RM,García-Pardo G,Olona M,Prats E,Mirapeix E,Rodríguez R,Richart C

    更新日期:1998-01-17 00:00:00

  • [Genetic polymorphisms of the renin-angiotensin system and essential hypertension].

    abstract:BACKGROUND:The renin-angiotensin system (RAS) plays an important role in blood pressure (BP) regulation. A number of RAS polymorphisms have been linked to essential hypertension (EH), but there is uncertainty about this association in other studies. We examined whether the insertion/deletion (I/D) polymorphism of the a...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:

    authors: Fernández-Llama P,Poch E,Oriola J,Botey A,de la Sierra A,Revert L,Rivera F,Darnell A

    更新日期:1999-05-01 00:00:00

  • [Calcified aortic valve disease: association with atherosclerosis].

    abstract::Calcified aortic valve disease (CAVD) is a prevalent condition, affecting 25% of people older than 65 years. CAVD and atherosclerosis share common risk factors and pathogenic mechanisms. Nevertheless, they present different pathologic lesions. The main factors involved in the pathogenesis of CAVD are genetic predispos...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/j.medcli.2010.02.019

    authors: Toro R,Mangas A,Gómez F

    更新日期:2011-05-14 00:00:00

  • [Determination of the lymphocytic and oncofetal antigen subpopulations in patients with adenocarcinomas of the stomach and of the colon and rectum (author's transl)].

    abstract::The authors present a study of 50 patients with adenocarcinomas of the colon and rectum, patients with gastric adenocarcinomas, and 30 healthy individuals as a control group. In all subjects the following parameters were determined: total number of lymphocytes in the peripheral blood, T lymphocytes, T-active lymphocyt...

    journal_title:Medicina clinica

    pub_type: 杂志文章

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    authors: Voltas J,Sanz ML,Hernández JL,Crisci CD,Subirá ML,Zornoza G

    更新日期:1979-12-15 00:00:00

  • [Spanish public opinion concerning organ donation and transplantation].

    abstract:BACKGROUND:Information, beliefs, attitudes and the motivations of the Spanish population regarding organ donation and transplantation were studied to facilitate possible programs directed at the promotion of organ donation. METHODS:The Psychosocial Aspects of Donation Questionnaire (PADQ) was applied by personal inter...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Martínez JM,Martín A,López JS

    更新日期:1995-10-07 00:00:00

  • [Cardiovascular complications at 1-year of follow-up in patients with atherothrombosis. On behalf of Spain's REACH Registry].

    abstract:BACKGROUND AND OBJECTIVE:The REACH Registry is the largest worldwide designed to obtain information on cardiovascular risk factor control and preventive treatment in a population who have, or are at risk of having, symptoms of atherothrombosis. The objective of this study is to show the results of cardiovascular events...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2008.11.033

    authors: Suárez C,Castillo J,Esmatjes E,Sala J,Cairols M,Montoto C,Barberá G,en representación de los investigadores del registro REACH España.

    更新日期:2009-04-18 00:00:00

  • [Gender differences in early reperfusion treatment after myocardial infarction].

    abstract:BACKGROUND AND OBJECTIVE:Clinical variability in myocardial infarction (MI) regarding age, comorbidities and atypical symptoms could determine gender differences in inhospital care. This study analyzes the magnitude and determinants of differences between men and women in early reperfusion therapy in people hospitalize...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(07)72497-1

    authors: Aldasoro E,Calvo M,Esnaola S,Hurtado de Saracho I,Alonso E,Audicana C,Arós F,Lekuona I,Arteagoitia JM,Basterretxea M,Marrugat J,IBERICA-País Vasco Group.

    更新日期:2007-01-27 00:00:00