[Merkel cell cancer of the skin: population-based incidence and survival, 1995-2005].

Abstract:

BACKGROUND AND OBJECTIVE:We aimed to assess the population-based incidence and survival of primary Merkel cell carcinoma. MATERIAL AND METHOD:From January 1995 to December 2005, 19 patients diagnosed with primary Merkel cell carcinoma were recruited in the population-based Cancer Registry of Girona. RESULTS:The age-adjusted incidence was 1,3 per 10(6) person-year; higher in males (1,5) than in females (1,1). Cases occurred mostly in people older than 65 years (94,7%), especially involving the head (79%). CONCLUSIONS:To our knowledge, this study is the first to define the incidence and survival of Merkel cell carcinoma in Europe. The age-adjusted incidence of primary Merkel cell carcinoma in our area is similar than the age-adjusted incidence of the 2000 US standard population.

journal_name

Med Clin (Barc)

journal_title

Medicina clinica

authors

Vilar-Coromina N,Pérez Bueno F,Alsina Maqueda M,Vilardell Gil L,Izquierdo Font A,Marcos-Gragera R

doi

10.1016/j.medcli.2008.10.056

subject

Has Abstract

pub_date

2009-05-16 00:00:00

pages

701-3

issue

18

eissn

0025-7753

issn

1578-8989

pii

S0025-7753(09)00391-1

journal_volume

132

pub_type

杂志文章
  • [Evolution of the prevalence of HIV-1 infection in drug addicts in the Community of Madrid (1985-1986)].

    abstract:BACKGROUND:To evaluate the evolution of the HIV infection in the drug addicts of Madrid. PATIENTS AND METHODS:Data of 2,234 patients that entered for the first time in a Psychiatric Hospital Detoxication Unit of Madrid from October 1985 to december 1996 were recorded. RESULTS:There was a reduction of the percentage o...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Sopelana P,Carrascosa C,García-Benito P

    更新日期:1998-09-12 00:00:00

  • [SLC7A9 gene variation: impact of 13 frequent mutations in the etiology of cystinuria in a Spanish Mediterranean population].

    abstract:BACKGROUND AND OBJECTIVE:The aim of this study was to investigate the presence of the most prevalent mutation in the SLC7A9 gene in families of the Mediterranean Spanish population and their association with clinical phenotypes. PATIENTS AND METHOD:Twenty cystinuria families were studied (6 type I, 12 non type I, and ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13090704

    authors: Francés F,Portolés O,Corella D,Sorlí JV,Sabater A,Carrasco P,Guillén M

    更新日期:2006-07-01 00:00:00

  • [Association of VCR-5FU-CYCLO-PDN in the treatment of disseminated carcinoma of the breast (author's transl)].

    abstract::A group of 32 patients with disseminated breast cancer were submitted to polychemotherapy following Cooper's protocol. Vincristine, cyclophosphamide, 5-fluorouracil, and prednisone were administered. The fifth drug used by Cooper, methotrexate, was not included in the therapy program because of difficulties in obtaini...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Estapé J,Millá A,Prats M,Herranz M,Visa J

    更新日期:1979-08-15 00:00:00

  • [Bacteremia and sepsis due to Streptococcus agalactiae. Study of eight cases (author's transl)].

    abstract::During a period of 29 months positive hemocultures to Streptococcus agalactiae corresponding to eight adult patients have been observed. These bacteria were apparently responsible for the clinical picture in five patients. In other two patients S. agalactiae appeared in the course of a sepsis caused by other germ. The...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Sánchez Ariõ MA,Moya Mir MS,Martin Martin F,Escolar Castellón F,Barbadillo R,Martin Jiménez TM,Zaldivar E,Dámaso D

    更新日期:1980-09-25 00:00:00

  • [antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease].

    abstract:BACKGROUND:The aim of the present study was to determine the prevalence and diagnostic usefulness of antineutrophil cytoplasmic antibodies (ANCA) in a Spanish population of patients with inflammatory bowel disease from the province of Tarragona. PATIENTS AND METHODS:One hundred and fifty-six sera obtained from 116 pat...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Papo M,Quer JC,Pastor RM,García-Pardo G,Olona M,Prats E,Mirapeix E,Rodríguez R,Richart C

    更新日期:1998-01-17 00:00:00

  • Metformin improves survival in lung cancer patients with type 2 diabetes mellitus: A meta-analysis.

    abstract:BACKGROUND AND OBJECTIVE:In recent years, many studies have investigated metformin and its effects on lung cancer. However, since previous studies have shown that the relationship between metformin and lung cancer is complicated, we performed a meta-analysis to analyze this relationship. MATERIAL AND METHODS:An electr...

    journal_title:Medicina clinica

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.medcli.2018.06.026

    authors: Zeng S,Gan HX,Xu JX,Liu JY

    更新日期:2019-04-18 00:00:00

  • Vertebral osteomyelitis: Clinical, microbiological and radiological characteristics of 116 patients.

    abstract:INTRODUCTION/OBJECTIVES:To describe the clinical, radiological and microbiological characteristics of vertebral osteomyelitis patients, analysing the factors that played a role on their outcome. PATIENTS AND METHODS:Single-centre retrospective observational study including patients diagnosed with vertebral osteomyelit...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2019.12.029

    authors: Fragío Gil JJ,González Mazarío R,Salavert Lleti M,Román Ivorra JA

    更新日期:2020-10-23 00:00:00

  • [The evolution and prognosis of disability in patients with hemiplegia].

    abstract:BACKGROUND:In order to plan the objectives of the rehabilitation treatment after a stroke, it is necessary to know the functional prognosis of the patient. The main prognostic factors of disability in the hemiplegic patient, by means of an analysis of his neurological deficits (aphasia, disorientation, urinary incontin...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(00)71602-2

    authors: Pinedo Otaola S,de La Villa MF

    更新日期:2000-10-21 00:00:00

  • [Is medical care adequate in cases of the common cold? The result of an evaluation in 8 health centers].

    abstract:BACKGROUND:In this study the quality of health care provided in cases of the common cold and similar was studied. These diseases were selected to seek opportunities for improvement for health care professionals by the nominal group technique. METHODS:A retrospective study of the health care procedures was carried out ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Saturno Hernández PJ,Gascón Cánovas JJ,Fonseca Miranda Y

    更新日期:1995-04-15 00:00:00

  • [Outbreak of foodborne disease by Norwalk-like viruses genogroup II].

    abstract:BACKGROUND:Our goal was to investigate the epidemiological characteristics and etiology of an outbreak of food-borne disease caused by Norwalk-like viruses, genogroup II. PATIENTS AND METHOD:We performed a historical cohort study on the consumption of 21 food items and clinical symptoms. We assessed RNA Norwalk-like v...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(02)73298-3

    authors: Godoy P,Prat A,Alsedà M,Torres J,Domínguez A,Salleras L

    更新日期:2002-06-08 00:00:00

  • [Uveitis as initial manifestation of sarcoidosis: study of 31 patients].

    abstract:BACKGROUND AND OBJECTIVE:Our goal was to analyze the epidemiological and clinical findings, as well as the diagnostic approach in a group of patients in whom uveitis was the first manifestation of sarcoidosis. PATIENTS AND METHOD:Retrospective study (between March 1998 and July 2002) including 31 patients diagnosed wi...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(04)74374-2

    authors: Adán A,Baget M,De Llobet JM,Segura A,Marieges MT,Casaroli-Marano R

    更新日期:2004-05-22 00:00:00

  • [Dysbaric accident in deep sea fishing].

    abstract::The case of a dysbaric accident with occurred in a professional athlete during a national competition is herein reported. The clinical symptoms and response to treatment in a depressurization chamber in addition to CT controls should alert physicians in coastal areas in which this sport is carried out in order to take...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: López Oblaré B,Campos Pascual F

    更新日期:1995-05-20 00:00:00

  • [Medical decisions in patients with chronic obstructive pulmonary disease].

    abstract:BACKGROUND:A right information about illness is essential if a patient has to take ethically autonomous medical decisions. We assessed whether a group o patients with chronic obstructive pulmonary disease (COPD) had enough information about their illness to take medical decisions. PATIENTS AND METHOD:Structured interv...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(01)71896-9

    authors: Miró Andreu G,Félez Flor M,Solsona Durán JF

    更新日期:2001-04-21 00:00:00

  • [Multiple chemical sensitivity: study of 52 cases].

    abstract:BACKGROUND AND OBJECTIVE:Multiple chemical sensitivity (MCS) is characterized by a loss of tolerance to various environmental chemicals. The objective of this study was to describe patients with MCS seen in our hospital. PATIENTS AND METHOD:Patients consecutively seen by the Toxicology and Chronic Fatigue Units who pr...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13107370

    authors: Nogué S,Fernández-Solá J,Rovira E,Montori E,Fernández-Huerta JM,Munné P

    更新日期:2007-06-16 00:00:00

  • [Environmental factors during early life and socioeconomic status in the present: which is more important for cardiovascular mortality in Spain?].

    abstract:BACKGROUND:To examine whether provincial mortality from ischaemic heart disease and cerebrovascular disease in Spain in 1991-1995 is associated with infant mortality in 1930-1934, independently of illiteracy (an estimator of socioeconomic status) in 1991. MATERIAL AND METHODS:Population-correlation study. RESULTS:Inf...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Guallar-Castillón P,Rodríguez Artalejo F,Banegas Banegas JR,de Andrés Manzano B,del Rey Calero J

    更新日期:1999-10-16 00:00:00

  • [Antenatal exposure to corticosteroids for fetal lung maturation and its repercussion on weight, length and head circumference in the newborn infant].

    abstract:BACKGROUND AND OBJECTIVE:To study the effects of antenatal corticosteroids treatment to promote fetal lung maturation, on fetal growth, depending on the number of the courses administered. PATIENTS AND METHOD:The study was based on data from the Spanish Collaborative Study of Congenital Malformations (ECEMC), analysin...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13092436

    authors: Rodríguez-Pinilla E,Prieto-Merino D,Dequino G,Mejías C,Fernández P,Martínez-Frías ML,Grupo del ECEMC.

    更新日期:2006-09-16 00:00:00

  • [Neoplasms associated with human immunodeficiency virus infection. Study of the clinical course of 70 patients].

    abstract:BACKGROUND:A different epidemiologic pattern of the neoplasms associated to the human immunodeficiency virus (HIV) has been described in the Mediterranean area. The aim of the present study was to analyze the epidemiologic, clinical and evolutive characteristics of these patients. METHODS:A retrospective study of 74 n...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Pintado V,López-Dupla JM,Valencia ME,Lavilla P,Martín A,González MD,García-Puig J,Gil A

    更新日期:1993-05-15 00:00:00

  • [Time series in the epidemiology of typhoid fever in Spain].

    abstract:BACKGROUND:The incidence of typhoid fever in Spain from January 1982 to December 1993 was studied with the aim of analyzing how the disease has evolved over these years and predict its future behavior in order to facilitate prevention by the public health care organizations and centers. MATERIAL AND METHODS:The Box-Je...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Ríos M,García JM,Cubedo M,Pérez D

    更新日期:1996-05-11 00:00:00

  • [Liver retransplantation: outcome analysis in 50 patients].

    abstract:BACKGROUND AND OBJECTIVE:Liver re-transplantation (re-LT) is an accepted indication for some (technical problems, primary non-function [PNF]) but not all indications, particularly recurrence of the original disease, such as hepatitis C. We aimed to determine in our center: a) the rate of survival following re-transplan...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13075442

    authors: Landaverde C,Berenguer M,Aguilera V,San Juan F,Prieto M,Berenguer J

    更新日期:2005-05-21 00:00:00

  • [Diagnostic usefulness of the determination of serum neuron-specific enolase in small cell bronchial carcinoma].

    abstract::The plasma level of neuron-specific enolase (NSE) was measured in 55 patients with small cell bronchial carcinoma (SCC) with cytohistological confirmation to evaluate its diagnostic usefulness. As a control group, 132 patients with non-small cell bronchial carcinoma, 81 with non-neoplastic disease and 37 healthy indiv...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Romero S,Padilla I,Mauri M,García-Sevila R,Martín C,Pérez-Carbonell A

    更新日期:1990-06-02 00:00:00

  • [Appropriateness of admissions to an internal medicine service at a tertiary hospital].

    abstract::In the present study, clinical, epidemiological and management factors influencing the appropriateness of the 1076 admissions to a general Internal Medicine Section during one year are evaluated. 184 admissions (17%) corresponded to patients who did not meet the AEP (Appropriateness Evaluation Protocol) criteria for a...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Matorras Galán P,de Pablo Casas M,Otero García L,Alonso López F,Daroca Pérez R,Díaz-Caneja Rodríguez N

    更新日期:1990-03-03 00:00:00

  • [Hyperimmunoglobulinemia D and periodic fever syndrome. A phenotypical analysis of a Spanish family].

    abstract:BACKGROUND:Hyperimmunoglobulinemia D and periodic fever syndrome (HIDS) is a disorder diagnosed with low frequency, that produces a very prolonged and recurrent fever with other symptoms and analytical markers of inflammation. Its origin seems to be hereditary with a recessive autosomic pattern, but its pathogenic mech...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(00)71331-5

    authors: García-Díaz JD,Alvarez-Blanco MJ

    更新日期:2000-04-01 00:00:00

  • [Optic neuritis, brain stem syndromes and myelitis: rapid conversion to multiple sclerosis].

    abstract:BACKGROUND:To establish the early risk of multiple sclerosis (MS) following isolated demyelinating syndromes. PATIENTS AND METHOD:36 patients with optic neuritis, 24 with brainstem syndromes, 27 with spinal cord syndromes and 8 patients with a poliregional syndrome were included in a prospective protocol: including cl...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Tintoré M,Rovira A,Hernández D,Río J,Marzo ME,Montalban X

    更新日期:1999-05-22 00:00:00

  • [Paraoxonase, something more than an enzyme?].

    abstract::Coronary heart disease is one of the major causes of death in developed countries. The hypothesis that peroxidation of low density lipoproteins (LDL) may be the initial step of the atherosclerotic process has promoted numerous studies aimed at investigating the mechanisms by which the body protects itself from such ox...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/s0025-7753(03)74011-1

    authors: Canales A,Sánchez-Muniz FJ

    更新日期:2003-10-25 00:00:00

  • [Histiocytic lymphoma and pulmonary fibrosis in a female patient with essential thrombocythemia].

    abstract::The case of a patient with the diagnosis of essential thrombocythemia is presented. Following treatment with melphalan during three years the patient presented clinical and radiologic data of pulmonary fibrosis. Thoracotomy with lung biopsy histologically proving fibrosis was performed. The patient developed a true hi...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:

    authors: Morla J,Pérez-Encinas M,Antela C,Pérez E,Barrio E

    更新日期:1993-01-23 00:00:00

  • [Use and presentation of statistics methods in original articles published in MEDICINA CLINICA in 1993].

    abstract:BACKGROUND:In the last few years a marked increase has been observed in the use of statistical techniques in biomedical publications. Some characteristics of the statistical quality of the first 100 articles consecutively published in 1993 in the section of originals and surveys of the journal MEDICINA CLINICA are pres...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Mora Ripoll R,Ascaso Terrén C,Sentís Vilalta J

    更新日期:1995-06-03 00:00:00

  • [Transforming growth factor beta (TGF-beta) in Gaucher's disease. Preliminary results in a group of patients and their carrier and non-carrier relatives].

    abstract:BACKGROUND:The poor phenotype/genotype correlation in Gaucher's disease makes difficult therapy-decision-making and prevention of complications. Gaucher's cells and tissue fibrosis are the earliest findings of the disease. Transforming growth factor ss (TGF-beta1) is the key cytokine involved in the regulation of tissu...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(00)71637-x

    authors: Pérez Calvo JI,Iñigo Gil P,Giraldo Castellano P,Torralba Cabeza MA,Civeira F,Lario García S,Pocoví M

    更新日期:2000-11-11 00:00:00

  • [Incidence of nosocomial infection surveillance in general surgery].

    abstract:BACKGROUND:We have not found any study assessing the sensitivity of different frequencies of nosocomial infection surveillance (NIS). The objective of this study is to contribute to the ascertainment of the frequency of the NIS surveillance in surgical patients, where NIS has shown to be most efficient. METHODS:A pros...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Delgado-Rodríguez M,Medina Cuadros M,Martínez Gallego G,Fariñas Alvarez C,Sillero Arenas M

    更新日期:1997-02-08 00:00:00

  • [Smoking paradox in acute coronary syndrome without ST-segment elevation].

    abstract:BACKGROUND AND OBJECTIVE:Although smoking habit is a well-known cardiovascular risk factor, it has been described that smokers admitted because of myocardial infarction have better prognosis than non smoker patients, which is known as "the smoking paradox". The purpose of our work is to investigate whether this phenome...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2010.01.039

    authors: Amor-Salamanca A,Devesa-Cordero C,Cuesta-Díaz A,Carballo-López MC,Fernández-Ortiz A,García-Rubira JC

    更新日期:2011-02-19 00:00:00

  • Arterial stiffness in normotensive and hypertensive subjects: Frequency in community pharmacies.

    abstract:BACKGROUND AND OBJECTIVE:Arterial stiffness (AS) is a well-recognized target organ lesion. This study aims to determine: 1) the frequency of AS in community pharmacies; 2) if stiffened subjects identified by brachial oscillometry have more CV risk factors than normal subjects, and 3) the dependence of stiffness on usin...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2017.04.037

    authors: Rodilla Sala E,Adell Alegre M,Giner Galvañ V,Perseguer Torregrosa Z,Pascual Izuel JM,Climent Catalá MT,en nombre del Grupo de estudio RIVALFAR.

    更新日期:2017-12-07 00:00:00