Abstract:
BACKGROUND AND OBJECTIVE:We aimed to assess the population-based incidence and survival of primary Merkel cell carcinoma. MATERIAL AND METHOD:From January 1995 to December 2005, 19 patients diagnosed with primary Merkel cell carcinoma were recruited in the population-based Cancer Registry of Girona. RESULTS:The age-adjusted incidence was 1,3 per 10(6) person-year; higher in males (1,5) than in females (1,1). Cases occurred mostly in people older than 65 years (94,7%), especially involving the head (79%). CONCLUSIONS:To our knowledge, this study is the first to define the incidence and survival of Merkel cell carcinoma in Europe. The age-adjusted incidence of primary Merkel cell carcinoma in our area is similar than the age-adjusted incidence of the 2000 US standard population.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Vilar-Coromina N,Pérez Bueno F,Alsina Maqueda M,Vilardell Gil L,Izquierdo Font A,Marcos-Gragera Rdoi
10.1016/j.medcli.2008.10.056subject
Has Abstractpub_date
2009-05-16 00:00:00pages
701-3issue
18eissn
0025-7753issn
1578-8989pii
S0025-7753(09)00391-1journal_volume
132pub_type
杂志文章相关文献
MEDICINA CLINICA文献大全abstract:BACKGROUND:To evaluate the evolution of the HIV infection in the drug addicts of Madrid. PATIENTS AND METHODS:Data of 2,234 patients that entered for the first time in a Psychiatric Hospital Detoxication Unit of Madrid from October 1985 to december 1996 were recorded. RESULTS:There was a reduction of the percentage o...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1998-09-12 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The aim of this study was to investigate the presence of the most prevalent mutation in the SLC7A9 gene in families of the Mediterranean Spanish population and their association with clinical phenotypes. PATIENTS AND METHOD:Twenty cystinuria families were studied (6 type I, 12 non type I, and ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13090704
更新日期:2006-07-01 00:00:00
abstract::A group of 32 patients with disseminated breast cancer were submitted to polychemotherapy following Cooper's protocol. Vincristine, cyclophosphamide, 5-fluorouracil, and prednisone were administered. The fifth drug used by Cooper, methotrexate, was not included in the therapy program because of difficulties in obtaini...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1979-08-15 00:00:00
abstract::During a period of 29 months positive hemocultures to Streptococcus agalactiae corresponding to eight adult patients have been observed. These bacteria were apparently responsible for the clinical picture in five patients. In other two patients S. agalactiae appeared in the course of a sepsis caused by other germ. The...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-09-25 00:00:00
abstract:BACKGROUND:The aim of the present study was to determine the prevalence and diagnostic usefulness of antineutrophil cytoplasmic antibodies (ANCA) in a Spanish population of patients with inflammatory bowel disease from the province of Tarragona. PATIENTS AND METHODS:One hundred and fifty-six sera obtained from 116 pat...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1998-01-17 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In recent years, many studies have investigated metformin and its effects on lung cancer. However, since previous studies have shown that the relationship between metformin and lung cancer is complicated, we performed a meta-analysis to analyze this relationship. MATERIAL AND METHODS:An electr...
journal_title:Medicina clinica
pub_type: 杂志文章,meta分析
doi:10.1016/j.medcli.2018.06.026
更新日期:2019-04-18 00:00:00
abstract:INTRODUCTION/OBJECTIVES:To describe the clinical, radiological and microbiological characteristics of vertebral osteomyelitis patients, analysing the factors that played a role on their outcome. PATIENTS AND METHODS:Single-centre retrospective observational study including patients diagnosed with vertebral osteomyelit...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2019.12.029
更新日期:2020-10-23 00:00:00
abstract:BACKGROUND:In order to plan the objectives of the rehabilitation treatment after a stroke, it is necessary to know the functional prognosis of the patient. The main prognostic factors of disability in the hemiplegic patient, by means of an analysis of his neurological deficits (aphasia, disorientation, urinary incontin...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71602-2
更新日期:2000-10-21 00:00:00
abstract:BACKGROUND:In this study the quality of health care provided in cases of the common cold and similar was studied. These diseases were selected to seek opportunities for improvement for health care professionals by the nominal group technique. METHODS:A retrospective study of the health care procedures was carried out ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1995-04-15 00:00:00
abstract:BACKGROUND:Our goal was to investigate the epidemiological characteristics and etiology of an outbreak of food-borne disease caused by Norwalk-like viruses, genogroup II. PATIENTS AND METHOD:We performed a historical cohort study on the consumption of 21 food items and clinical symptoms. We assessed RNA Norwalk-like v...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(02)73298-3
更新日期:2002-06-08 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Our goal was to analyze the epidemiological and clinical findings, as well as the diagnostic approach in a group of patients in whom uveitis was the first manifestation of sarcoidosis. PATIENTS AND METHOD:Retrospective study (between March 1998 and July 2002) including 31 patients diagnosed wi...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(04)74374-2
更新日期:2004-05-22 00:00:00
abstract::The case of a dysbaric accident with occurred in a professional athlete during a national competition is herein reported. The clinical symptoms and response to treatment in a depressurization chamber in addition to CT controls should alert physicians in coastal areas in which this sport is carried out in order to take...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1995-05-20 00:00:00
abstract:BACKGROUND:A right information about illness is essential if a patient has to take ethically autonomous medical decisions. We assessed whether a group o patients with chronic obstructive pulmonary disease (COPD) had enough information about their illness to take medical decisions. PATIENTS AND METHOD:Structured interv...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(01)71896-9
更新日期:2001-04-21 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Multiple chemical sensitivity (MCS) is characterized by a loss of tolerance to various environmental chemicals. The objective of this study was to describe patients with MCS seen in our hospital. PATIENTS AND METHOD:Patients consecutively seen by the Toxicology and Chronic Fatigue Units who pr...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13107370
更新日期:2007-06-16 00:00:00
abstract:BACKGROUND:To examine whether provincial mortality from ischaemic heart disease and cerebrovascular disease in Spain in 1991-1995 is associated with infant mortality in 1930-1934, independently of illiteracy (an estimator of socioeconomic status) in 1991. MATERIAL AND METHODS:Population-correlation study. RESULTS:Inf...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-10-16 00:00:00
abstract:BACKGROUND AND OBJECTIVE:To study the effects of antenatal corticosteroids treatment to promote fetal lung maturation, on fetal growth, depending on the number of the courses administered. PATIENTS AND METHOD:The study was based on data from the Spanish Collaborative Study of Congenital Malformations (ECEMC), analysin...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13092436
更新日期:2006-09-16 00:00:00
abstract:BACKGROUND:A different epidemiologic pattern of the neoplasms associated to the human immunodeficiency virus (HIV) has been described in the Mediterranean area. The aim of the present study was to analyze the epidemiologic, clinical and evolutive characteristics of these patients. METHODS:A retrospective study of 74 n...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1993-05-15 00:00:00
abstract:BACKGROUND:The incidence of typhoid fever in Spain from January 1982 to December 1993 was studied with the aim of analyzing how the disease has evolved over these years and predict its future behavior in order to facilitate prevention by the public health care organizations and centers. MATERIAL AND METHODS:The Box-Je...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1996-05-11 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Liver re-transplantation (re-LT) is an accepted indication for some (technical problems, primary non-function [PNF]) but not all indications, particularly recurrence of the original disease, such as hepatitis C. We aimed to determine in our center: a) the rate of survival following re-transplan...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13075442
更新日期:2005-05-21 00:00:00
abstract::The plasma level of neuron-specific enolase (NSE) was measured in 55 patients with small cell bronchial carcinoma (SCC) with cytohistological confirmation to evaluate its diagnostic usefulness. As a control group, 132 patients with non-small cell bronchial carcinoma, 81 with non-neoplastic disease and 37 healthy indiv...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1990-06-02 00:00:00
abstract::In the present study, clinical, epidemiological and management factors influencing the appropriateness of the 1076 admissions to a general Internal Medicine Section during one year are evaluated. 184 admissions (17%) corresponded to patients who did not meet the AEP (Appropriateness Evaluation Protocol) criteria for a...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1990-03-03 00:00:00
abstract:BACKGROUND:Hyperimmunoglobulinemia D and periodic fever syndrome (HIDS) is a disorder diagnosed with low frequency, that produces a very prolonged and recurrent fever with other symptoms and analytical markers of inflammation. Its origin seems to be hereditary with a recessive autosomic pattern, but its pathogenic mech...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71331-5
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:To establish the early risk of multiple sclerosis (MS) following isolated demyelinating syndromes. PATIENTS AND METHOD:36 patients with optic neuritis, 24 with brainstem syndromes, 27 with spinal cord syndromes and 8 patients with a poliregional syndrome were included in a prospective protocol: including cl...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-05-22 00:00:00
abstract::Coronary heart disease is one of the major causes of death in developed countries. The hypothesis that peroxidation of low density lipoproteins (LDL) may be the initial step of the atherosclerotic process has promoted numerous studies aimed at investigating the mechanisms by which the body protects itself from such ox...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/s0025-7753(03)74011-1
更新日期:2003-10-25 00:00:00
abstract::The case of a patient with the diagnosis of essential thrombocythemia is presented. Following treatment with melphalan during three years the patient presented clinical and radiologic data of pulmonary fibrosis. Thoracotomy with lung biopsy histologically proving fibrosis was performed. The patient developed a true hi...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:
更新日期:1993-01-23 00:00:00
abstract:BACKGROUND:In the last few years a marked increase has been observed in the use of statistical techniques in biomedical publications. Some characteristics of the statistical quality of the first 100 articles consecutively published in 1993 in the section of originals and surveys of the journal MEDICINA CLINICA are pres...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1995-06-03 00:00:00
abstract:BACKGROUND:The poor phenotype/genotype correlation in Gaucher's disease makes difficult therapy-decision-making and prevention of complications. Gaucher's cells and tissue fibrosis are the earliest findings of the disease. Transforming growth factor ss (TGF-beta1) is the key cytokine involved in the regulation of tissu...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71637-x
更新日期:2000-11-11 00:00:00
abstract:BACKGROUND:We have not found any study assessing the sensitivity of different frequencies of nosocomial infection surveillance (NIS). The objective of this study is to contribute to the ascertainment of the frequency of the NIS surveillance in surgical patients, where NIS has shown to be most efficient. METHODS:A pros...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1997-02-08 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Although smoking habit is a well-known cardiovascular risk factor, it has been described that smokers admitted because of myocardial infarction have better prognosis than non smoker patients, which is known as "the smoking paradox". The purpose of our work is to investigate whether this phenome...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2010.01.039
更新日期:2011-02-19 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Arterial stiffness (AS) is a well-recognized target organ lesion. This study aims to determine: 1) the frequency of AS in community pharmacies; 2) if stiffened subjects identified by brachial oscillometry have more CV risk factors than normal subjects, and 3) the dependence of stiffness on usin...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2017.04.037
更新日期:2017-12-07 00:00:00