[Current use of statistics in biomedical research: a comparison of general medicine journals].

Abstract:

BACKGROUND:The use of statistical techniques has become strongly consolidated in biomedical investigation. The present study analyzes the statistical repertoire of the original articles published in 1993 in four general medicine journals: Med Clin (Barc), Rev Clin Esp, Lancet and N Engl J Med. METHODS:A single reviewer examined 100 original articles from Med Clin (Barc), 42 from Rev Clin Esp, 105 from Lancet and 116 from N Engl J Med, studying the use of 18 categories of statistical analysis and the statistical accessibility of the reader. The criteria for assigning techniques to a specific category were those described by Emerson and Colditz. The knowledge of bivariable techniques (standard reader) was established as the reference for the study of statistical access. Statistical use consisted in the tabulation of frequencies, graphic representations and chi square tests. RESULTS:The five most used categories were: Contingency tables, t and z tests, epidemiologic statistics, survival analysis (in both English journals) and analysis of variance (in both Spanish journals). The percentage of articles without statistics or with only descriptive statistics was 16% in Med Clin (Barc), 29% in Rev Clin Esp, 18% for in Lancet and 23% in the N Engl J Med. A reader familiarized with bivariable techniques has statistical access to 58% for the originals of Med Clin (Barc), 62% of Rev Clin Esp, 35% of the Lancet and 42% of the N Engl J Med. CONCLUSIONS:In the four journals selected, the use of bivariable techniques is still frequent although the growing use of multivariant analysis is of note. The study of the current profile of the standard reader in Spain is the aim of priority.

journal_name

Med Clin (Barc)

journal_title

Medicina clinica

authors

Mora Ripoll R,Ascaso Terrén C,Sentís Vilalta J

subject

Has Abstract

pub_date

1996-03-30 00:00:00

pages

451-6

issue

12

eissn

0025-7753

issn

1578-8989

journal_volume

106

pub_type

杂志文章
  • [Anaesthesia and thromboembolic disease].

    abstract::Currently, pharmacological thromboprophylaxis is frequently required in patients undergoing surgery, due to the high risk of deep venous thrombosis in the perioperative period. The administration of these anticoagulant agents (in Spain, usually low molecular weight heparins or fondaparinux, and in future, probably als...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/s0025-7753(08)76448-0

    authors: Llau JV,Sapena ML,López Forte C,Ferrandis R

    更新日期:2008-11-01 00:00:00

  • Correlation between epicardial fat thickness and biochemical markers of metabolic risk.

    abstract:INTRODUCTION AND OBJECTIVE:Epicardial fat has been associated with increased cardiovascular risk and the development of atherosclerosis. Transthoracic echocardiography provides a reliable measurement of epicardial fat thickness (EFT). The aim of this study is to evaluate the relationship between EFT and biochemical par...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2018.01.019

    authors: Rubio-Guerra AF,Benítez-Maldonado DR,Lozano-Nuevo JJ,Arana-Pazos KC,Huerta-Ramirez S,Narváez-Rivera JL

    更新日期:2018-09-21 00:00:00

  • [The therapeutic effort on admission for women with an acute myocardial infarct. The Valencia Group for the Study of Hospital Inequities in Health].

    abstract:BACKGROUND:Recent studies have suggested that women with ischemic heart disease receive lesser therapeutic care than males. The aim of this study was to verify the hypothesis that sex is an independent predictive factor in therapeutic care upon admission in patients with acute myocardial infarction. METHODS:Secondary ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Latour Pérez J

    更新日期:1994-03-19 00:00:00

  • [Hematologic aspects of alcoholism (author's transl)].

    abstract::Alcohol causes different hematologic alterations on each of the three bone marrow cellular series. Its effect on the red series leads to the appearance of megaloblastic disturbances, erythroblastic vacuolization, iron metabolism abnormalities, and hemolytic syndromes. Megaloblastic disturbances may arise as a conseque...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Alvarez-Sala Walther JL,Urbán Poza MA,Sicilia de Salamanca JJ,Fernández Mendieta F,Serrano Heranz R,Espinós Pérez D

    更新日期:1979-02-25 00:00:00

  • Usefulness of bronchoalveolar lavage and flow cytometry in patients with hematological malignancies and respiratory failure.

    abstract:BACKGROUND AND OBJECTIVES:Strategies to improve the efficiency of bronchoalveolar lavage (BAL) are needed. We conducted a study to establish the diagnostic value of BAL in patients with hematological malignancies and pulmonary infiltrates. PATIENTS AND METHODS:The correlation of cytologic and flow cytometric study of ...

    journal_title:Medicina clinica

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.medcli.2016.10.045

    authors: Ferrà C,Xicoy B,Castillo N,Morgades M,Juncà J,Andreo F,Millá F,Feliu E,Ribera JM

    更新日期:2017-04-07 00:00:00

  • Analysis of biomedical Spanish articles retracted between 1970 and 2018.

    abstract:BACKGROUND AND OBJECTIVE:To analyse articles retracted due to irregularities by authors helps to determine the state of scientific integrity of a discipline or country. The Retraction Watch (RW) database is the largest worldwide database on retracted articles. The objective was to determine the reasons for and features...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2019.04.018

    authors: Dal-Ré R

    更新日期:2020-02-28 00:00:00

  • [Guidelines for the prevention and control of tuberculosis in health care workers].

    abstract::Tuberculosis remains one of the communicable diseases that cause increased morbidity and mortality worldwide. With an incidence rate of 13,04 per 100,000 population, Spain ranks third among the most affected European countries. These data show a tendency to decrease meaning that it may go unnoticed with the potential ...

    journal_title:Medicina clinica

    pub_type: 共识发展会议,杂志文章,实务指引

    doi:10.1016/j.medcli.2015.06.018

    authors: Casas I,Dominguez J,Rodríguez S,Matllo J,Altet N,SEPAR.,GEIM.,SEIMC.,AEEMT.,Programa de Prevención y control de la Tuberculosis (Catalan Public Health Agency).

    更新日期:2015-12-21 00:00:00

  • [Relationship in cardiovascular reactivity to mental stress and early involvement of target organs in non-treated mild arterial hypertension. Hospitalet Study].

    abstract:BACKGROUND:It has been previously reported that an exaggerated response of blood pressure to mental stress tasks is associated to an increased cardiovascular risk. The objective of this cross-sectional study, with sequential inclusion of subjects who met the inclusion criteria, was to asses the relationships between th...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Armario P,Hernández del Rey R,Torres G,Martín-Baranera M,Cruz Almendros M,Pardell H

    更新日期:1999-10-09 00:00:00

  • [Effectiveness, safety and cost-effectiveness of the negative pressure wound therapy on the treatment of chronic wounds: a systematic review].

    abstract::Negative-pressure wound therapy (NPWT) is used to promote wound healing by using suction to drain excess fluid from wounds. A systematic literature review was undertaken to assess the effectiveness, safety and cost-effectiveness of NPWT for the treatment of chronic wounds. Medline, Embase, CENTRAL, CINAHL and the Coch...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/j.medcli.2010.06.010

    authors: Trujillo-Martín M,García-Pérez L,Serrano-Aguilar P

    更新日期:2011-09-17 00:00:00

  • [Podoconiosis, a society and medical community neglected disease].

    abstract::Podoconiosis, mossy foot or endemic non-filarial elephantiasis, is a geochemical disease that causes lower limb lymphedema; it is directly related to walking barefoot over soils of volcanic origin, in areas with a high pluviometric annual index. It has a specific geographical distribution, affecting around 5% populati...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/j.medcli.2014.12.020

    authors: Prieto-Pérez L,Soriano Cea JJ,Górgolas Hernández-Mora M

    更新日期:2015-11-20 00:00:00

  • Adherence to recommendations of the Therapeutic Positioning Report about treatment with oral anticoagulants in elderly patients with atrial fibrillation. The ESPARTA study.

    abstract:BACKGROUND AND OBJECTIVE:To evaluate the adherence to the recommendations in clinical practice performed by the Therapeutic Positioning Report (TPR) of the Spanish Agency of Medicines and Sanitary Products about the treatment with oral anticoagulants in patients aged≥75 years old with nonvalvular atrial fibrillation (N...

    journal_title:Medicina clinica

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.medcli.2017.07.025

    authors: Suárez Fernández C,Mostaza JM,Castilla Guerra L,Cantero Hinojosa J,Suriñach JM,Acosta de Bilbao F,Tamarit JJ,Diaz Diaz JL,Hernandez JL,Cazorla D,Ràfols C,en nombre de los Investigadores del Estudio ESPARTA.

    更新日期:2018-07-13 00:00:00

  • [Histiocytic lymphoma and pulmonary fibrosis in a female patient with essential thrombocythemia].

    abstract::The case of a patient with the diagnosis of essential thrombocythemia is presented. Following treatment with melphalan during three years the patient presented clinical and radiologic data of pulmonary fibrosis. Thoracotomy with lung biopsy histologically proving fibrosis was performed. The patient developed a true hi...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:

    authors: Morla J,Pérez-Encinas M,Antela C,Pérez E,Barrio E

    更新日期:1993-01-23 00:00:00

  • [Influence of comorbidity on admission management and pharmacological treatment prescribed at discharge in acute myocardial infarction].

    abstract:BACKGROUND AND OBJECTIVE:The management of cardiac ischemic patients differs depending on their comorbidity. The Charlson Index (ChI) and its adaptations are well established and widely used tools to quantify a patient comorbidity. The aim of this study is to evaluate the influence of comorbidity quantified by the ChI ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13073218

    authors: Fácila Rubio L,Núñez Villota J,Bertomeu González V,Sanchís Fores J,Bodi Peris V,Consuegra Sánchez L,Sanjuán Mañez R,Llácer Escorihuela A

    更新日期:2005-04-02 00:00:00

  • [Chronic myeloid leukemia after chemotherapy treatment for non-Hodgkin's lymphoma].

    abstract::A 52 year old male presenting chronic myeloid leukemia (CML) Philadelphia chromosome positive (Ph) four years after the diagnosis of a non Hodgkin's lymphoma is described. The patient had received high total doses of alkylating drugs (cyclophosphamide and chlorambucil) as part of chemotherapy treatment for a diffuse m...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Sacanella E,Cervantes F,Navarro M,Terol MJ,Estruch R,Montserrat E,Rozman C

    更新日期:1992-06-20 00:00:00

  • [Distribution of serotypes A and B of Candida albicans in 502 strains isolated from pathological specimens].

    abstract:BACKGROUND:Candida albicans is distributed in at least two serological groups (A and B) depending on its antigenic structure. These characteristics have been used to investigate the epidemiology of candidiasis. No information is available in this country about the distribution of these serotypes in a general population...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Torres-Rodríguez JM,Nicolás MC,Madrenys N,Gallach C

    更新日期:1991-06-01 00:00:00

  • [Relevance of diabetes in high cardiovascular risk hypertensive patients].

    abstract:BACKGROUND AND OBJECTIVE:The aim of this cross-sectional study was to compare the prevalence of target organ damage (TOD) and established cardiovascular disease (CVD) in a cohort of nondiabetic hypertensive patients with 3 or more cardiovascular risk factors (CVRF) against a group of hypertensives with type 2 diabetes....

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2012.05.032

    authors: Segura J,de la Sierra A,Fernández S,Ruilope LM,en representación de los investigadores del estudio IDENTCARE.

    更新日期:2013-10-05 00:00:00

  • Pulmonary arterial hypertension associated to systemic erythematosus lupus: molecular characterization of 3 cases.

    abstract:BACKGROUND AND OBJECTIVE:Pulmonary arterial hypertension associated with systemic lupus erythematosus (PAH-SLE) is a rare disease with a low incidence rate. In this study, PAH related genes and genetic modifiers were characterised molecularly in patients with PAH-SLE. PATIENTS AND METHODS:Three patients diagnosed with...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2018.01.023

    authors: Pousada G,Lago-Docampo M,Baloira A,Valverde D

    更新日期:2018-08-10 00:00:00

  • [Hyperimmunoglobulinemia D and periodic fever syndrome. A phenotypical analysis of a Spanish family].

    abstract:BACKGROUND:Hyperimmunoglobulinemia D and periodic fever syndrome (HIDS) is a disorder diagnosed with low frequency, that produces a very prolonged and recurrent fever with other symptoms and analytical markers of inflammation. Its origin seems to be hereditary with a recessive autosomic pattern, but its pathogenic mech...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(00)71331-5

    authors: García-Díaz JD,Alvarez-Blanco MJ

    更新日期:2000-04-01 00:00:00

  • [What is a "poison"? Proposal of definition].

    abstract::We discuss different interpretations of the term poison as well as the need of bringing up to date the changes in this matter according to the science progress. A clear and exact definition is proposed after analysing the factors that affect the relativity of the concept and its boundaries. The proposal for a definiti...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2011.02.002

    authors: Guitart R,Giménez N

    更新日期:2012-02-18 00:00:00

  • Sporadic inclusion body myositis: Diagnostic value of p62 immunostaining.

    abstract:BACKGROUND AND OBJECTIVES:Sporadic inclusion body myositis (sIBM) diagnosis is frequently delayed or confused with another class of disorders, and misdiagnosis is common. Sometimes, we have problems diagnosing an sIBM in the early stages or predicting when a PM is going to become an sIBM. In this sense, we believe that...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2019.04.022

    authors: Milisenda JC,García AM,Jou C,Pinal-Fernandez I,O'Callaghan AS,Grau JM

    更新日期:2019-12-13 00:00:00

  • [Emergency hospital admission in medical services: causes, justification, social factors, and their differences in function of age].

    abstract:BACKGROUND:Increasing attention has been given to the care to elderly patients in emergency departments (ED). Moreover, few data are available about final phase of the process, that is hospital admission from ED. This study was conducted to establish appropriateness, reasons and social factors related to hospital admis...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: González-Montalvo JI,Baztán JJ,Rodríguez-Mañas L,San Cristóbal E,Gato A,Ballesteros P,Salgado A

    更新日期:1994-10-15 00:00:00

  • [Bone metabolism and fracture risk in anorexia nervosa].

    abstract::The prevalence of anorexia nervosa has increased in recent years and a large proportion of patients with this disorder have low bone density at diagnosis and, therefore, an increased risk of early and late fractures. The mechanism of bone loss in anorexia nervosa is not well understood, yet it likely includes hypogona...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/j.medcli.2009.04.046

    authors: Fernández Soto ML,González Jiménez A,Varsavsky M

    更新日期:2010-07-17 00:00:00

  • Characterization and risk factors for aortic dilatation in pediatric patients with bicuspid aortic valve.

    abstract:INTRODUCTION AND OBJECTIVES:Dilatation of the ascending aorta associated with bicuspid aortic valve is a major cause of morbidity and mortality in adults. The main objective was to recognize the aortic involvement in children, its characteristics and risk factors. METHODS:Aortic measures of all pediatric patients with...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2017.03.041

    authors: Sabaté-Rotés A,Sabidó Sanchez L,Gran Ipiña F,Albert Brotons D,Abella RF,Rosés Noguer F

    更新日期:2017-11-09 00:00:00

  • [Usefulness of polymerase chain reaction for the diagnosis of Bazin erythema induratum].

    abstract:BACKGROUND:Erythema induratum of Bazin (BEI), is included in the group of cutaneous granulomatous lobulillar panniculitis. The aethiopathogenic association between EI and tuberculosis can not rely on the clinicohistological features of these panniculitis and M. tuberculosis has never been isolated from BEI lesions. Det...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Margall N,Baselga E,Coll P,Barnadas M,Sánchez F,de Moragas JM,Prats G

    更新日期:1996-11-30 00:00:00

  • [Comparative analysis between the use of renin-angiotensin system antagonists and clinical outcomes of hospitalized patients with COVID-19 respiratory infection].

    abstract:INTRODUCTION:Hypertension has been associated with worse outcomes in patients with COVID-19 infection, so concerns have been raised about the possibility that inhibitors of the renin-angiotensin system (RAS) could influence the prognosis of these patients. METHODS:This is an observational study of 921 consecutive pati...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2020.07.004

    authors: Martínez-Del Río J,Piqueras-Flores J,Nieto-Sandoval Martín de la Sierra P,Negreira-Caamaño M,Águila-Gordo D,Mateo-Gómez C,Salas-Bravo D,Rodríguez-Martínez M

    更新日期:2020-12-11 00:00:00

  • [Alterations of previous potentials of somatosensory cerebral evoked potential after lesions of the brain-stem (author's transl)].

    abstract::The characteristics of previous potentials of somatosensory evoked potential in 12 patients with lesions of the brain-stem and in 24 normal individuals have been studied. Lesions of the brain-stem were confirmed by means of computerized axial tomography, arteriography or necropsy. According to data reported by other a...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Obeso JA,Marti Massó JF,Iragui MI,Maravi E,Carrera N,Teijeira J

    更新日期:1980-09-25 00:00:00

  • [Rapid progression to AIDS in a patient with infection from a strain of syncytium forming HIV-1].

    abstract::A woman who had recently become infected with HIV-1 after sexual relations with a seropositive subject presented a rapid fall in CD4+ T lymphocytes and evolved to AIDS 13 months after primoinfection. The most plausible cause for the rapid disease progression in this patient was the observation of a viral syncytium for...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Soriano V,Heredia A,Bravo R,Gutiérrez M,González-Lahoz J

    更新日期:1995-06-17 00:00:00

  • [ACT/AA polymorphism could duplicate the APOE*epsilon4-associated Alzheimer's disease risk].

    abstract:BACKGROUND AND OBJECTIVE:The association between the presence of the allele APOE*epsilon4 (apolipoprotein E) and sporadic Alzheimer disease (AD) has been long established. However, the possible influence of other genetic factors is still under debate. This study investigated the role of the a 1-antichymotrypsin (ACT) g...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(04)74479-6

    authors: Hernández-Charro B,Moreno S,Valiente A,Manubens JM,Villar MD,Ramos-Arroyo MA

    更新日期:2004-09-04 00:00:00

  • [Design and implementation of a multicenter case-control study on bladder cancer in Spain].

    abstract::The aim of a case-control design is to make a measurement of the highest possible accuracy, reducing to a minimum the possible selection, information and confusion biases. The design, methods and procedures of a multicentric study carried out in 14 hospitals from 4 autonomous communities in Spain are discussed. Overal...

    journal_title:Medicina clinica

    pub_type: 临床试验,杂志文章,多中心研究

    doi:

    authors: González CA,López-Abente G,Errezola M,Escolar A,Izarzugaza I,Riboli E,Nebot M

    更新日期:1989-05-06 00:00:00

  • [The evolution and prediction of the incidence of breast cancer in Zaragoza, 1961-2000].

    abstract:BACKGROUND:Using the data available from the Cancer Registry of Zaragoza, the incidence of breast cancer in women from 1961 to 1985 was analyzed with future evolution being predicted up to the year 2000. METHODS:The age, period and birth cohort effects, in addition to the place of residence (capital/rest of province) ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Vioque J,Navarro Gracia JF,Millas Ros J,Mateo de las Heras E

    更新日期:1993-05-29 00:00:00