Abstract：
:The prevalence of anorexia nervosa has increased in recent years and a large proportion of patients with this disorder have low bone density at diagnosis and, therefore, an increased risk of early and late fractures. The mechanism of bone loss in anorexia nervosa is not well understood, yet it likely includes hypogonadism, alterations of the GH-IGF-1 axis and hypercortisolism. DEXA is the most effective tool for assessing and monitoring bone density in these patients, and it is important to improve or at least stabilize bone metabolism in those with low bone mass. No agent has yet been proven to be effective in improving bone density. However, sustained weight recovery and menses besides an adequate intake of calcium and vitamin D are recommended to optimize the conditions in which bone mass accrual may occur.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Fernández Soto ML,González Jiménez A,Varsavsky Mdoi
10.1016/j.medcli.2009.04.046subject
Has Abstractpub_date
2010-07-17 00:00:00pages
274-9issue
6eissn
0025-7753issn
1578-8989pii
S0025-7753(09)00931-2journal_volume
135pub_type
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