Abstract：
BACKGROUND AND OBJECTIVE:To describe an outbreak of Legionella pneumophila serogroup 1 in Mataró, Catalunya, Spain, in August 2002. The source of the microorganism was a cooling tower. PATIENTS AND METHOD:Prospective and observational study with analysis of epidemiological, clinical, and microbiological data. RESULTS:151 patients were affected (62% male), with a mean age of 58.4 years old. Seven patients were classified as Pontiac Fever and 144 suffered from pneumonia. The diagnosis of pneumonia was confirmed in 79% of cases, was considered suspicious in 14% and probable in 7%. Forty per cent of patients were smokers and 53.5% had comorbidities, mainly diabetes mellitus (22%). Chief symptoms were fever (97%), chills and muscular pain (63% respectively), headache (54%) and cough (53%). Pulmonary condensation was the more frequent radiological feature (71%). Normal pulmonary exploration was observed in 38%. Forty-three per cent of cases were severely ill, and 16% of patients belonged to Fine's IV and V class. Antigenuria was the most important test for diagnosis, which confirmed 76% of cases. Legionella spp. was obtained in respiratory secretions of 10 patients. Molecular analysis confirmed clonality between respiratory microorganisms and that obtained in the cooling tower. CONCLUSION:The outbreak involved an important number of subjects in a short period of time. Antigenuria was the most useful test. However, the isolation of L. pneumophila from patients permitted the prompt identification of microorganism's source in a cooling tower. The low mortality observed probably relates to a rapid diagnosis and its target treatment.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Barrufet-Barqué MP,Sauca-Subias G,Force-Sanmartín L,Felip-Benach A,Martínez-Pérez E,Capdevila-Morell JAdoi
10.1016/s0025-7753(06)71871-1keywords:
subject
Has Abstractpub_date
2006-02-11 00:00:00pages
178-82issue
5eissn
0025-7753issn
1578-8989pii
S0025-7753(06)71871-1journal_volume
126pub_type
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