Na-coupled bicarbonate transporters of the solute carrier 4 family in the nervous system: function, localization, and relevance to neurologic function.

abstract：:Developmental or degenerative damage of the neuronal architecture in the entorhinal cortex may disintegrate a functional part of hippocampal input since the entorhinal cortex provides a major source of neocortical and subcortical input to the hippocampus. These alterations, such as seen in Alzheimer's disease, schizop...

journal_title：Neuroscience

authors： Falkenberg T,Metsis M,Timmusk T,Lindefors N

更新日期：1993-12-01 00:00:00

abstract：:Recent studies have demonstrated that total cellular levels of voltage-gated potassium channel subunits can change on a time scale of minutes in acute slices and cultured neurons, raising the possibility that rapid changes in the abundance of channel proteins contribute to experience-dependent plasticity in vivo. In o...

journal_title：Neuroscience

authors： Strumbos JG,Polley DB,Kaczmarek LK

更新日期：2010-05-19 00:00:00

abstract：:Previous findings, mainly in in vitro systems, have shown that the density of vesicles and the synaptic efficacy at excitatory synapses are reduced in the absence of synapsins, despite the fact that transgenic mice lacking synapsins develop an epileptic phenotype. Here we study glutamate receptors by quantitative immu...

journal_title：Neuroscience

authors： Gylterud Owe S,Bogen IL,Walaas SI,Storm-Mathisen J,Bergersen LH

更新日期：2005-01-01 00:00:00

abstract：:In mice, the compact hippocampal primordium is formed during the prenatal stage by early-generated neurons that migrate from the lateral ventricular zone. However, despite much being understood about the formation of the hippocampus, the molecular mechanisms that maintain the morphology of the hippocampal primordium a...

journal_title：Neuroscience

authors： Wang HT,Zeng L,Chen Q,Zhang X,Liu JW,Lu TJ,Xiong ZQ,Zheng J,Hu ZL

更新日期：2015-01-22 00:00:00

abstract：:In the European rabbit (Oryctolagus cuniculus) nursing acts as a strong non-photic synchronizer of circadian rhythmicity in the newborn young. Rabbits only nurse for a few minutes once every 24 h and previous studies have shown that the pups, blind at birth, display endogenous circadian rhythms in behavior and physiol...

journal_title：Neuroscience

authors： Caldelas I,Tejadilla D,González B,Montúfar R,Hudson R

更新日期：2007-01-19 00:00:00

abstract：:Recent studies investigating neural correlates of human thirst have identified various subcortical and telencephalic brain areas. The experience of thirst represents a homeostatic emotion and a state that slowly evolves over time. Therefore, the present study aims at systematically examining cerebral perfusion during ...

journal_title：Neuroscience

authors： Meier L,Federspiel A,Jann K,Wiest R,Strik W,Dierks T

更新日期：2018-07-15 00:00:00

abstract：:Extremely mild hypothermia to 36.0 °C is not thought to appreciably differ clinically from 37.0 °C. However, it is possible that 36.0 °C stimulates highly sensitive hypothermic signaling mechanism(s) and alters biochemistry. To the best of our knowledge, no such ultra-sensitive pathway/mechanisms have been described. ...

journal_title：Neuroscience

authors： Jackson TC,Manole MD,Kotermanski SE,Jackson EK,Clark RS,Kochanek PM

更新日期：2015-10-01 00:00:00

abstract：:Cervical or high thoracic spinal cord injury often results in autonomic dysreflexia, a condition characterized by exaggerated spinal reflexes and episodic hypertension, that may be caused by reorganization of synapses on sympathetic preganglionic neurons after loss of supraspinal input. To assess remodelling of synapt...

journal_title：Neuroscience

authors： Weaver LC,Cassam AK,Krassioukov AV,Llewellyn-Smith IJ

更新日期：1997-11-01 00:00:00

abstract：:Our previous studies indicate that endogenous opioids (primarily beta-endorphin) released during stressful stimuli can interact with peripheral opioid receptors to inhibit nociception in inflamed tissue of rats. This study sought to localize opioid precursor mRNAs and opioid peptides deriving therefrom in inflamed tis...

journal_title：Neuroscience

authors： Przewłocki R,Hassan AH,Lason W,Epplen C,Herz A,Stein C

更新日期：1992-01-01 00:00:00

abstract：:Healthy aging is accompanied by neurobiological changes that affect the brain's functional organization and the individual's cognitive abilities. The aim of this study was to investigate the effect of global age-related differences in the cortical white and gray matter on neural activity in three key large-scale netwo...

journal_title：Neuroscience

authors： Marstaller L,Williams M,Rich A,Savage G,Burianová H

更新日期：2015-04-02 00:00:00

abstract：:We have systematically characterized neuronal survival and growth in cultures derived from newborn/postnatal day 1 mouse cochlea. Dissociated cultures of the cochlear spiral ganglion provide an experimental environment in which to examine molecular mechanisms of survival, development and physiology of auditory neurons...

journal_title：Neuroscience

authors： Whitlon DS,Ketels KV,Coulson MT,Williams T,Grover M,Edpao W,Richter CP

更新日期：2006-01-01 00:00:00

abstract：:We investigated the effects of intracerebroventricular injection of angiotensin II on neuronal immediate early gene-encoded protein synthesis in the brain of conscious rats. The expression of seven immediate early gene-encoded transcription factors (c-Fos, FosB, c-Jun, JunB, JunD, Krox-20 (Egr-2) and Krox-24 (NGFI-A, ...

journal_title：Neuroscience

authors： Lebrun CJ,Blume A,Herdegen T,Seifert K,Bravo R,Unger T

更新日期：1995-03-01 00:00:00

abstract：:Adenosine trisphosphate-sensitive potassium (K-ATP) channels in the substantia nigra pars reticulata were studied in rat brain slices using whole-cell patch clamp recording. Substantia nigra pars reticula neurons were identified as such by their spontaneous action potential firing at mean rate of 15.3 Hz1 virtual abse...

journal_title：Neuroscience

authors： Stanford IM,Lacey MG

更新日期：1996-09-01 00:00:00

abstract：:Previous studies from our laboratory and others have shown that there are major age-related differences in brainstem neuronal function. Since GABAA receptors are major targets for GABA-mediated inhibitory modulation and play a key role in regulating cardiorespiratory function, especially during O2 deprivation, we exam...

journal_title：Neuroscience

authors： Xia Y,Haddad GG

更新日期：1992-08-01 00:00:00

abstract：:The transforming growth factor beta-activated kinase 1 (TAK1), a member of the Mitogen-activated protein kinase kinase kinase family, is characterized as a key regulator in inflammatory and apoptosis signaling pathways. The aim of the present study was to evaluate the role of the TAK1 pathway in experimental traumatic...

journal_title：Neuroscience

authors： Zhang D,Hu Y,Sun Q,Zhao J,Cong Z,Liu H,Zhou M,Li K,Hang C

更新日期：2013-05-15 00:00:00

abstract：:Many of the different morphological types of interneurons in mammalian neocortex are presumed to be inhibitory, but to date, conclusive functional data have been lacking. Using paired intracellular recordings in slices of adult rat somatosensory cortex, we present a sparsely spiny, burst firing interneuron that elicit...

journal_title：Neuroscience

authors： Deuchars J,Thomson AM

更新日期：1995-04-01 00:00:00

abstract：:Prostaglandin E(1) is frequently used for the clinical treatment of acute sensorineural hearing loss. However, the mechanisms underlying the effects of prostaglandin E(1) on the inner ear have not yet been elucidated. The physiological effects of prostaglandin E(1) are mediated by the prostanoid receptors prostaglandi...

journal_title：Neuroscience

authors： Hori R,Nakagawa T,Sugimoto Y,Sakamoto T,Yamamoto N,Hamaguchi K,Ito J

更新日期：2009-06-02 00:00:00

abstract：:The main neuronal population of the striatum is composed of the medium spiny neurones (MSNs). In fact several sub-populations of MSNs can be distinguished according to the striatal compartment (striosomes and matrix) to which they belong, their afferents and their sites of projection, their biochemical markers and the...

journal_title：Neuroscience

authors： Venance L,Glowinski J

更新日期：2003-01-01 00:00:00

abstract：:Accumulating evidence indicates that activation of spinal cord astrocytes contributes importantly to nerve injury and inflammation-induced persistent pain and chronic opioid-induced antinociceptive tolerance. Phosphorylation of extracellular signal-regulated kinase (pERK) and induction of interleukin-1 beta (IL-1β) in...

journal_title：Neuroscience

authors： Berta T,Liu YC,Xu ZZ,Ji RR

更新日期：2013-09-05 00:00:00

abstract：:The membrane properties and receptor-mediated responses of rat dorsal raphe nucleus neurons were measured using intracellular recording techniques in a slice preparation. After each experiment, the recorded neuron was filled with neurobiotin and immunohistochemically identified as 5-hydroxytryptamine (5-HT)-immunoposi...

journal_title：Neuroscience

authors： Kirby LG,Pernar L,Valentino RJ,Beck SG

更新日期：2003-01-01 00:00:00

abstract：:Both GABA and glycine (Gly) containing neurons send inhibitory projections to the inferior colliculus (IC), whereas inhibitory neurons within the IC are primarily GABAergic. To date, however, a quantitative description of the topographic distribution of GABAergic neurons in the rat's IC and their GABAergic or glyciner...

journal_title：Neuroscience

authors： Merchán M,Aguilar LA,Lopez-Poveda EA,Malmierca MS

更新日期：2005-01-01 00:00:00

abstract：:Nuclear factor-kappa B (NF-κB) is a ubiquitous transcription factor that regulates immune and cell-survival signaling pathways. NF-κB has been reported to be present in neurons wherein it reportedly responds to immune and toxic stimuli, glutamate, and synaptic activity. However, because the brain contains many cell ty...

journal_title：Neuroscience

authors： Listwak SJ,Rathore P,Herkenham M

更新日期：2013-10-10 00:00:00

abstract：:While chronic pain is a main symptom in endometriosis, the underlying mechanisms and effective therapy remain elusive. We developed an animal model enabling the exploration of ectopic endometrium as a source of endometriosis pain. Rats were surgically implanted with autologous uterus in the gastrocnemius muscle. Withi...

journal_title：Neuroscience

authors： Alvarez P,Chen X,Hendrich J,Irwin JC,Green PG,Giudice LC,Levine JD

更新日期：2012-12-06 00:00:00

abstract：:Factors involved in the production of long-term potentiation in the CA1 region of rat hippocampal slices were examined using whole-cell voltage clamp recordings. The pairing of postsynaptic membrane depolarization with tetanic stimulation produced a reliable long-lasting enhancement of synaptic currents provided that ...

journal_title：Neuroscience

authors： Kato K,Clifford DB,Zorumski CF

更新日期：1993-03-01 00:00:00

abstract：:Mesolimbic beta-, but not alpha-adrenoceptors control the accumbal release of dopamine that is derived from alpha-methyl-para-tyrosine-sensitive pools of newly synthesized neurotransmitter. The aim of this study was to investigate which of these adrenoceptors control the accumbal release of dopamine that is derived fr...

journal_title：Neuroscience

authors： Verheij MM,Cools AR

更新日期：2009-09-15 00:00:00

abstract：:Previous research has demonstrated that diabetes induces learning and memory deficits. However, the mechanism of memory impairment induced by diabetes is poorly understood. Dietary fatty acids, especially polyunsaturated fatty acids, have been shown to enhance learning and memory and prevent memory deficits in various...

journal_title：Neuroscience

authors： Jia D,Heng LJ,Yang RH,Gao GD

更新日期：2014-01-31 00:00:00

abstract：:Thyroid hormones (TH) are essential for normal brain development. Even modest degrees of TH disruption experienced in utero can result in neuropsychological deficits in children despite normal thyroid status at birth. Neurotrophins have been implicated in a host of brain cellular functions, and in particular, brain-de...

journal_title：Neuroscience

authors： Gilbert ME,Lasley SM

更新日期：2013-06-03 00:00:00

abstract：:The location of sympathetic preganglionic neurons (SPN) in the spinal cord of the reeler mouse mutant is abnormal. Instead of their normal location in the intermediolateral column, the majority of SPN in the reeler cluster around the central canal. To determine whether ectopically located SPN in the reeler form approp...

journal_title：Neuroscience

authors： Yip YP,Rinaman L,Capriotti C,Yip JW

更新日期：2003-01-01 00:00:00

abstract：:Recent studies have demonstrated that astrocytes express a variety of ion channels and neurotransmitter receptors and can modulate the activity of neurons. Since a single astrocyte makes tight contacts with many neighboring neuronal cells, they can provide efficient and wide modulation of neuronal networks. Here, we p...

journal_title：Neuroscience

authors： Yamazaki Y,Hozumi Y,Kaneko K,Li J,Fujii S,Miyakawa H,Kudo Y,Kato H

更新日期：2005-01-01 00:00:00

abstract：:Insulin-like growth factor binding protein-2 binds insulin-like growth factors I and II with high affinity and modulates the interaction of these ligands with the type I insulin-like growth factor receptor. Previously we have shown that insulin-like growth factor binding protein-2 and insulin-like growth factor-I gene...

journal_title：Neuroscience

authors： Lee WH,Michels KM,Bondy CA

更新日期：1993-03-01 00:00:00