Entorhinal cortex regulation of multiple brain-derived neurotrophic factor promoters in the rat hippocampus.

abstract：:Visceral sensory perception is subjected to modulation by attention or distraction, like other sensory systems. The thalamic reticular nucleus is a key region in selective attention, effecting a change in the mode of thalamocortical transmission. Each major thalamocortical system is connected with a particular sector ...

journal_title：Neuroscience

authors： Stehberg J,Acuña-Goycolea C,Ceric F,Torrealba F

更新日期：2001-01-01 00:00:00

abstract：:Several lines of research have implicated glutathione (GSH) in schizophrenia. For instance, GSH deficiency has been reported in the prefrontal cortex of schizophrenics in vivo. Further, in rats postnatal GSH-deficiency combined with hyperdopaminergia led to cognitive impairments in the adult. In the present report we ...

journal_title：Neuroscience

authors： Jacobsen JP,Rodriguiz RM,Mørk A,Wetsel WC

更新日期：2005-01-01 00:00:00

abstract：:We have examined the basic electrophysiology and pharmacology of cells in the anterior caudal lobe (CLa) of the mormyrid cerebellum. Intracellular recordings were performed in an in vitro slice preparation using the whole-cell patch recording method. The responses of cells to parallel fiber (PF) and climbing fiber (CF...

journal_title：Neuroscience

authors： Zhang Y,Magnus G,Han VZ

更新日期：2010-11-24 00:00:00

abstract：:The distributions of the alpha 1-adrenoceptor and its subtypes (alpha 1A and alpha 1B) in human and rat hippocampus are analysed by quantitative receptor autoradiography. alpha 1-Adrenoceptors are labelled by [3H]prazosin. The alpha 1A subtype is visualized by [3H]prazosin after irreversible blockade of alpha 1B adren...

journal_title：Neuroscience

authors： Zilles K,Gross G,Schleicher A,Schildgen S,Bauer A,Bahro M,Schwendemann G,Zech K,Kolassa N

更新日期：1991-01-01 00:00:00

abstract：:Systemically administered cholinomimetics or cholinesterase inhibitors can depress behavior in humans and animals, whereas antimuscarinic agents reverse this effect or even produce euphoria. Although these effects have been well documented, the specific brain regions that mediate them remain largely unknown. In the pr...

journal_title：Neuroscience

authors： Chau DT,Rada P,Kosloff RA,Taylor JL,Hoebel BG

更新日期：2001-01-01 00:00:00

abstract：:The functional changes of astrocytes are deeply involved in neurodegenerating processes of various CNS diseases. ATP is released during various neuronal damages such as brain ischemia and may control astrocyte functions. We examined the effect of ATP on the production of nitric oxide in the cultured astrocytes from ra...

journal_title：Neuroscience

authors： Murakami K,Nakamura Y,Yoneda Y

更新日期：2003-01-01 00:00:00

abstract：:N-methyl-D-aspartate-receptors are implicated in several neuropathological conditions including epilepsy. As a model of complex partial seizures, rapid hippocampal kindling was chosen to investigate changes in the expression of messenger RNAs encoding the N-methyl-D-aspartate-receptor subunits NR1, NR2A and NR2B both ...

journal_title：Neuroscience

authors： Pratt GD,Kokaia M,Bengzon J,Kokaia Z,Fritschy JM,Möhler H,Lindvall O

更新日期：1993-11-01 00:00:00

abstract：:The behavioral and motivational changes that result from use of abused substances depend upon activation of neuronal populations in the reward centers of the brain, located primarily in the corpus striatum in primates. To gain insight into the cellular mechanisms through which abused drugs reinforce behavior in the pr...

journal_title：Neuroscience

authors： Opris I,Hampson RE,Deadwyler SA

更新日期：2009-09-29 00:00:00

abstract：:Research in songbirds shows that singing behavior is regulated by both brain areas involved in vocal behavior as well as those involved in social behavior. Interestingly, the precise role of these regions in song can vary as a function of the social, environmental and breeding context. To date, little is known about t...

journal_title：Neuroscience

authors： Heimovics SA,Cornil CA,Ball GF,Riters LV

更新日期：2009-03-31 00:00:00

abstract：:Injecting 0.5-1.0 microgram of cholera toxin into rat hippocampus induces a chronic epileptic focus which generates interictal discharges and brief epileptic seizures intermittently over the following seven to 10 days. Here we examined the electrophysiological properties of hippocampal slices prepared from these rats ...

journal_title：Neuroscience

authors： Watts AE,Whittington MA,Jefferys JG

更新日期：1993-07-01 00:00:00

abstract：:The solitary nucleus (nucleus tractus solitarii), the first central relay for taste in mammals, was studied anatomically and physiologically in the golden hamster (Mesocricetus auratus). Activity of neurons to anterior tongue stimulation with sucrose, NaCl and KCl were extracellularly recorded. Electrolytic lesions or...

journal_title：Neuroscience

authors： McPheeters M,Hettinger TP,Nuding SC,Savoy LD,Whitehead MC,Frank ME

更新日期：1990-01-01 00:00:00

abstract：:Direct injections into the cerebroventricles have been extensively utilized in neurophysiological studies. Mapping the distribution of injectate after intracerebroventricular injection has been made only by post mortem analysis, and the dynamic distribution of injectate within the brain has not been well characterized...

journal_title：Neuroscience

authors： Bui JD,Nammari DR,Buckley DL,Inglis BA,Silver XS,Mareci TH,Phillips MI

更新日期：1999-03-01 00:00:00

abstract：:Chitinase activity is increased in Alzheimer's disease (AD). However, the role of chitinase1 in AD is unknown. We investigated the effects of chitinase1 on Alzheimer's pathology and microglia function. Artificial chitinase1 and chitinase inhibitor (chitinase-IN-2) were used to determine the effects of chitinase1 on in...

journal_title：Neuroscience

authors： Xiao Q,Yu W,Tian Q,Fu X,Wang X,Gu M,Lü Y

更新日期：2017-07-04 00:00:00

abstract：:In spite of the existence of pedunculopontine tegmental nucleus (PPTg) projections to cerebellar nuclei, their nature and functional role is unknown. These fibers may play a crucial role in postural control and may be involved in the beneficial effects induced by deep-brain stimulation (DBS) of brainstem structures in...

journal_title：Neuroscience

authors： Vitale F,Mattei C,Capozzo A,Pietrantoni I,Mazzone P,Scarnati E

更新日期：2016-03-11 00:00:00

abstract：:Origins and pathways of cerebrovascular substance P- and calcitonin gene-related peptide-positive nerves in rat were studied by immunohistochemistry combined with denervation experiments and retrograde axonal tracer technique. The two peptides have been found to coexist in one and the same neuron. After sectioning of ...

journal_title：Neuroscience

authors： Suzuki N,Hardebo JE,Owman C

更新日期：1989-01-01 00:00:00

abstract：:Among vertebrates hippocampus forms the major component of the brain in consolidating information from short-term memory to long-term memory. Aging is considered as the major risk factor for memory impairment in sporadic Alzheimer's disease (SAD) like pathology. Present study thus aims at investigating whether age-spe...

journal_title：Neuroscience

authors： Moorthi P,Premkumar P,Priyanka R,Jayachandran KS,Anusuyadevi M

更新日期：2015-08-20 00:00:00

abstract：:The primary visual (V1), auditory (AI), and somatosensory (SI) cortices are reciprocally connected with their respective sensory association cortices. In the rat, we have previously demonstrated that some of the connections arising from the secondary somatosensory (SII) and parietal insular (PA) cortices and terminati...

journal_title：Neuroscience

authors： Bai WZ,Ishida M,Arimatsu Y

更新日期：2004-01-01 00:00:00

abstract：:The ability to generate subthreshold membrane potential oscillations in neurons from the inferior olive nucleus has been attributed to the electrical properties of these neurons, as well as to the properties of the network. In the present in vitro study we quantitatively characterized both intrinsic membrane and netwo...

journal_title：Neuroscience

authors： Lampl I,Yarom Y

更新日期：1997-05-01 00:00:00

abstract：:In an attempt to evaluate the cellular organization and efferent projections of the nucleus tegmenti pedunculopontinus pars compacta, several experiments were performed in the rat. From measurements of neurons in the nucleus tegmenti pedunculopontinus pars compacta in Nissl-stained sections, the nucleus was observed t...

journal_title：Neuroscience

authors： Sugimoto T,Hattori T

更新日期：1984-04-01 00:00:00

abstract：:By employing both in vivo and in vitro labeling techniques, opiate receptors were labeled with tritiated diprenorphine in the monkey brain and localized by light microscopic autoradiography. Both methods of labeling gave similar results, allowing a description of discrete areas having opiate binding sites. High concen...

journal_title：Neuroscience

authors： Wamsley JK,Zarbin MA,Young WS 3rd,Kuhar MJ

更新日期：1982-03-01 00:00:00

abstract：:It is well established that transforming growth factor alpha is involved prenatally in development of the nervous system, but its role in the postnatal brain is less well understood. Here, we document the occurrence of late-onset, morphological and behavioral deficits in the naturally occurring murine mutant, Waved-1 ...

journal_title：Neuroscience

authors： Burrows RC,Levitt P,Shors TJ

更新日期：2000-01-01 00:00:00

abstract：:Cholesterol is an essential substance for maintaining normal structure and function of the brain. But unfortunately, a long-term high-cholesterol diet can lead to a variety of pathological changes of the brain such as β-amyloid (Aβ) accumulation, Tau hyperphosphorylation, reactive gliosis, neuroinflammation, neuronal ...

journal_title：Neuroscience

authors： Chen YL,Wang LM,Chen Y,Gao JY,Marshall C,Cai ZY,Hu G,Xiao M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Spasticity and rigidity are serious complications associated with spinal traumatic or ischemic injury. Clinical studies show that tizanidine (Tiz) is an effective antispasticity agent; however, the mechanism of this effect is still not clear. Tiz binds not only to α2-adrenoreceptors (AR) but also to imidazol...

journal_title：Neuroscience

authors： Fuchigami T,Kakinohana O,Hefferan MP,Lukacova N,Marsala S,Platoshyn O,Sugahara K,Yaksh TL,Marsala M

更新日期：2011-10-27 00:00:00

abstract：:Repeated non-reinforced exposures of a neutral stimulus retard the development of a conditioned response to that stimulus when it is subsequently paired with a significant event. This stimulus pre-exposure effect is known as latent inhibition (LI). Early lesion studies have initially suggested an important role for th...

journal_title：Neuroscience

authors： Pouzet B,Zhang WN,Weiner I,Feldon J,Yee BK

更新日期：2004-01-01 00:00:00

abstract：:The dual effect of capsaicin on primary afferent neurons, excitation and stimulation of transmitter release, its dependence on extracellular calcium and its modulation by Ruthenium Red have been investigated in the rabbit ear. Injection of capsaicin into the central artery of the isolated perfused ear with intact neur...

journal_title：Neuroscience

authors： Amann R,Donnerer J,Lembeck F

更新日期：1989-01-01 00:00:00

abstract：:The distribution and origin of nerves with calcitonin gene-related peptide, substance P or neurokinin A immunoreactivity in the walls of the cerebral arteries were investigated in three microchiropteran species. The supply of nerves immunoreactive for substance P and neurokinin A to the bat cerebral arteries is confin...

journal_title：Neuroscience

authors： Ando K,Arai S,Kawamura K

更新日期：1990-01-01 00:00:00

abstract：:Review of the normally occurring neuronal patterns of the hippocampus suggests that the two principal cell types of the hippocampus, the pyramidal neurons and granule cells, are maximally active during different behaviors. Granule cells reach their highest discharge rates during theta-concurrent exploratory activities...

journal_title：Neuroscience

authors： Buzsáki G

更新日期：1989-01-01 00:00:00

abstract：:Current neurobiological theory of drug use is based on the observation that all addictive drugs induce changes in activity of dopaminergic circuitry, interfering with reward processing, and thus enhancing drug seeking and consumption behaviors. Current theory of drug origins, in contrast, views almost all major drugs ...

journal_title：Neuroscience

authors： Hagen EH,Sullivan RJ,Schmidt R,Morris G,Kempter R,Hammerstein P

更新日期：2009-04-21 00:00:00

abstract：:We report that a small population of neurons expresses both choline acetyltransferase and classical estrogen receptor immunoreactivity and they are found primarily in the bed nucleus of the stria terminalis. In short-term ovariectomized ageing mice (24 months, n = 5) there were 41.0 +/- 4.1% fewer of these double-labe...

journal_title：Neuroscience

authors： Miller MM,Hyder SM,Assayag R,Panarella SR,Tousignant P,Franklin KB

更新日期：1999-01-01 00:00:00

abstract：:There is considerable evidence that on the anterior surface of the heart (which is usually supplied by the left anterior descending and the proximal part of the left circumflex coronary arteries), sympathetic efferent reflexes characterized by tachycardia and/or hypertension predominate following experimental or patho...

journal_title：Neuroscience

authors： Meller ST,Gebhart GF

更新日期：1992-01-01 00:00:00