Abstract：
INTRODUCTION:Endometrial carcinoma is a common malignancy of the female genital tract. There is a strong correlation between myometrial invasion and clinical prognosis. Increasing myometrial penetration is associated with an increasing risk of pelvic and para-aortic lymph node metastasis, adnexal metastasis, positive peritoneal cytology local vault recurrence, and hematogenous spread. The causal role for Insulin-like growth factor-1 and insulin in endometrial carcinogenesis is well supported and insulin and IGF system have mitogenic and antiapoptotic activity Endometrial cancer cell lines express high-affinity insulin receptors, consistent with there being a direct biological effect of insulin and IGF system on the growth and myometrial invasion of endometrial cancer cells. MATERIAL AND METHODS:Patients with endometrial carcinoma have been divided into three groups: tumor confined to the endometrium (stage IA, n:24), endometrial carcinoma with a minimal invasion (less than 50% of the myometrium; stage IB, n:32), and the control group (n:40). Demographic factors, estradiol and free IGF-1 plasma levels have been compared in all groups. RESULTS:Lower Free IGF-1 plasma levels were found in patients with myometrial invasion when compared to the patients without myomnetrial invasion. CONCLUSIONS:In the following work we have presented the current understanding of endometrial carcinoma, association between free IGF-1 plasma levels and myometrial invasion in patients with endometrial adenocarcinoma in terms of management and survival.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Baloglu A,Bezircioglu I,Cetinkaya B,Hicyilmaz Lsubject
Has Abstractpub_date
2010-07-01 00:00:00pages
501-5issue
7eissn
0017-0011issn
2543-6767journal_volume
81pub_type
杂志文章abstract：:The Impact Factor is a measure of average citation frequency for articles in a specific scientific journal during a specific period of time. IF takes into account the content, sources, layout and frequency and regularity of publishing. In order to get an impact factor, a journal needs to be first put on the Philadelph...
journal_title：Ginekologia polska
pub_type： 社论
doi：
更新日期：2010-10-01 00:00:00
abstract：:Bezoars are the most common foreign bodies of gastrointestinal tract. They contain swallowed hair, different fibres, seeds, nut shells, sweets or drugs. Clinical manifestations vary, depending on the location and size of bezoar, from "no symptoms" to "acute abdomen" syndrome. In this case report, the authors describe ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2008-04-01 00:00:00
abstract：:The concentration of N-terminal propeptide of type III procollagen (PIIINP) in umbilical cord serum was estimated in preterm and term newborns. The mean concentration of PIIINP was significantly higher in preterm infants, despite their lower body mass. This indicates higher rate of collagen biosynthesis in early gesta...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to investigate to what extent sweeping of the membranes contributes to cervical shortening and if cervical shortening is related to the time to onset of labor and duration of the active phase of labor METHODS:This prospective randomized clinical trial was performed at Baskent Univer...
journal_title：Ginekologia polska
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2014-09-01 00:00:00
abstract：UNLABELLED:The effective functions of human peripheral blood neutrophil are modulated by regulatory molecules depending on receptor agonists and adhesion molecules. OBJECTIVES:Evaluation of percentage of neutrophil adhesion molecules in pregnancy of diabetic mothers as well as their expression on peripheral blood neut...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：OBJECTIVE:To establish the normal range of embryonic heart rate (EHR) and foetal heart rate (FHR) at 6(+0) to 11(+6) weeks of gestation, to evaluate the risk of pregnancy loss depending on EHR and FHR values and to establish if checking of FHR with the use of M-mode method is possible in different levels obstetric depa...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2009-03-01 00:00:00
abstract：:Ultrasonic velocimetry of the fetal circulation became a very useful method in assessment of fetal well-being, especially in high risk pregnancies. There are many papers concerning on distribution and regulation of blood flow in umbilical artery, middle cerebral artery, and much less dealing with flow velocity wavefor...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2004-02-01 00:00:00
abstract：OBJECTIVES:From a theoretical viewpoint, intraperitoneal therapy (i.p.) in-patients with ovarian cancer, a malignancy, which remains mainly, confined to the peritoneal cavity is logical. Intraperitoneal catheters have moved to the forefront as a delivery system in cancer treatment. Authors have described complications ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to determine serum concentrations of a proinflammatory cytokine, tumor necrosis factor-alpha (TNF-α), in patients with recurrent abortions undergoing treatment with sildenafil or etanercept. MATERIAL AND METHODS:Serum TNF-α concentrations were determined for 24 patients with recurre...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/57823
更新日期：2015-07-01 00:00:00
abstract：:Gene therapy is an innovative way of treating genetic disorders, which enables removal or repair of genetic defects. Strategies of gene therapy offer new perspectives in treating cancer diseases. Numerous methods for specifically removing tumor cells are currently used. They can be divided into five main strategies: c...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2010-01-01 00:00:00
abstract：:We report a case of a 6-week cervical pregnancy successfully treated with systemic methotrexate and gestational sac biopsy with 15%-calcium chloride solution injection. Serial monitoring of human chorionic gonadotropin levels, combined with ultrasound examinations, confirmed spontaneous miscarriage. Applied treatment ...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2011-05-01 00:00:00
abstract：:The paper contains the description of the modification of simplified method for caesarean section, based on the Joel-Cohen and Misgav Ladach method. Advantages of the simplified methods are described on the basis of the cited papers. Following stages of procedure are described in details. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-04-01 00:00:00
abstract：OBJECTIVES:To analyzed the therapeutic results for patients with overlooked iatrogenic ureteral injuries after gynecological surgery, treated at the department since 1990. Before the era of endourology, ureteral injuries were operated on immediately after making a diagnosis. This approach was changed after the populari...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2016.0069
更新日期：2016-01-01 00:00:00
abstract：:Transvaginal sonography (TVS), computed tomography (CT) and magnetic resonance imaging (MRI) were used for preoperative diagnosis of myometrial and pelvic lymph nodes invasion in patients with endometrial cancer. Results of examinations were compared with histopathological findings. Sensitivity, specificity, efficacy,...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to verify clinical diagnosis of cervical incompetence by the use of transvaginal sonography. MATERIAL AND METHODS:101 pregnant women hospitalized at the Pathological Pregnancy Department, Medical University of Lodz in years 2000-2002 because of suspicion of cervical incompetence wer...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
abstract：:It was described two cases of vulvar melanoma malignum. Both women after primary radical treatment, unfortunately died. It was discussed the classification of melanoma malignum, the efficiency of treatment nowadays and the problems in diagnosis. General results of treatment are poor. It is due to tendency for spreadin...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：OBJECTIVE:Retrospective clinical and pathomorphological analysis of patients undergoing surgery due to endometrial carcinoma; analysis of the correlation between histological grading of endometrial cancer and selected pathomorphological results. MATERIAL AND METHODS:Statistical analysis was based on the pathomorpholog...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/2419
更新日期：2015-05-01 00:00:00
abstract：:We investigated the vitamin D receptor (VDR) and the estrogen receptor (ER) genes polymorphism in studied groups was similar, however the allelic combination BBPPxx was associated with low bone mineral mass. There is a need to perform genetic test in the cohort of polish women endangered by osteoporosis. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：OBJECTIVES:The study was designed to evaluate the effectiveness of cervical cancer prophylactics by identification of the time of last cervical cytological examination as well as by recognition of frequency of repeated cervical cytological examinations and reimbursement for the examination costs in representative sampl...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2005-11-01 00:00:00
abstract：:Natural cytotoxic activity in the umbilical blood was estimated in 52 healthy newborns. Mononuclear cells were isolated from the umbilical blood using Boym's method. The mean natural cell cytotoxicity in the examined group was 7.05 +/- 0.9 (SD). ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1996-02-01 00:00:00
abstract：:Breast cancer is often relatively slow growing, but at diagnosis about 40% of patients have regional spread to at least one axillary node. It has been shown that unrelated clones are in primary breast carcinomas. There is possibility that only a small subpopulation of the cells of the primary tumour (PT) metastasis. I...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:The expert panel recommendations are issued in order to increase the number of patients with urinary incontinence and overactive bladder receiving appropriate care. The expert panel recommends that urologists, gynecologists and other physicians interested in the field of incontinence should Incontinence question shoul...
journal_title：Ginekologia polska
pub_type： 杂志文章,实务指引
doi：
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to evaluate the concentrations of kynurenic acid (KYNA) in blood and urine during the normal pregnancy. MATERIALS AND METHODS:Under the study were 37 pregnant women. Level of KYNA was measured by high performance liquid chromatography (HPLC). RESULTS:The KYNA concentration in blood...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to test the relationship between maternal serum proinflammatory cytokines level and AFI (amniotic fluid index) in pregnancies complicated by premature rupture of membranes (PROM). MATERIALS AND METHODS:The maternal serum levels of IL-6, IL-1 beta and TNF-alfa were assessed in patient...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to evaluate hormonal contraception use in women with epilepsy and to assess the risk of potential interactions between contraceptives and antiepileptic drugs (AEDs). MATERIAL AND METHODS:Data on hormonal contraception were obtained prospectively in women of childbearing age treated ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2019.0010
更新日期：2019-01-01 00:00:00
abstract：:182 hysteroscopic operations with electroresectoscope use performed in Ist Department of Obstetrics and Gynaecology (Warsaw) between 1996-1999 were analyzed. Myomectomy was performed in 117 patients, resection of uterine septum in 25 and deliberation of intrauterine adhesions in 40 patients. Abnormal bleeding and infe...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVES:Intrahepatic cholestasis in pregnancy (ICP) is a pregnancy-specific liver disorder. Its etiology is not fully understood. Increasing evidence indicates the important role of vitamin D and the vitamin D receptor (VDR) in this disorder. The presence of polymorphic variants in the VDR gene could influence its a...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2020.0135
更新日期：2020-01-01 00:00:00
abstract：:The investigation were made of the seasonal occurrence of the upper respiratory tract inflammation and pneumonia probably caused by ch. trachomotis. The immunofluorescence tests of chlamydia trachomatis were done in the blood serum of 1831 children aged from 2 weeks to 6 years hospitalised in Wrocław. The research was...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：OBJECTIVES:Paternal lymphocytes immunization has been proposed for several years as an efficient treatment for unexplained Recurrent Spontaneous Abortion (RSA), however precise mechanism that underline the benefits of this immunotherapy is still unclear. DESIGN:The aim was to study the influence of paternal lymphocyte...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：:Higher rate of morbidity and mortality has been noted in tween pregnancies comparing to singleton pregnancies. Early ultrasound investigation between 6 and 12 week of gestation is useful in determining time of gestation, amniocity and chorionicity (adequacy of diagnosis ranged from 95 to 100%). Determining of chorioni...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2000-11-01 00:00:00
