Abstract:
OBJECTIVES:Paternal lymphocytes immunization has been proposed for several years as an efficient treatment for unexplained Recurrent Spontaneous Abortion (RSA), however precise mechanism that underline the benefits of this immunotherapy is still unclear. DESIGN:The aim was to study the influence of paternal lymphocytes immunization on percentage of peripheral blood NK cells (CD16+/CD56+) in women with primary RSA of unknown etiology. MATERIALS AND METHODS:48 patients with history of 3-5 (mean 3.3 +/- 0.7) consecutive primary RSA of unknown etiology were selected for the study. Immunotherapy with paternal lymphocytes, isolated from 100 ml of peripheral blood, was performed twice prior conception with a 4-week interval. The percentage of NK cells (CD16+/CD56+) was estimated using standard flow-cytometric immunofluorescent techniques for whole blood with one-step monoclonal anti-CD16/CD56 antibodies. Statistical analysis was performed with Wilcoxon test and the p value less than 0.05 was accepted as statistically significant. RESULTS:It was found that paternal lymphocytes immunization significantly decreases the percentage of NK cells in peripheral blood in women with RSA (23.9 +/- 8.5 vs. 16.2 +/- 7.0; p = 0.009). CONCLUSIONS:The data of the present studies suggest that paternal lymphocytes immunization modulate immunity in women with primary unexplained RSA significantly decreasing the percentage of NK cells (CD16+/CD56+) in peripheral blood.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Szpakowski A,Malinowski A,Zeman K,Wilczyński J,Kolasa D,Nowak M,Władziński J,Kamiński T,Szpakowski Mkeywords:
subject
Has Abstractpub_date
2001-12-01 00:00:00pages
1063-8issue
12eissn
0017-0011issn
2543-6767journal_volume
72pub_type
杂志文章abstract:OBJECTIVES:To analyze the prognosis and related risk factors of patients with scarred uterus complicated with central placenta previa. MATERIAL AND METHODS:A total of 272 parturient women admitted to our hospital between June 2013 and December 2016 were selected, of whom 142 cases with central placenta previa were des...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.2019.0033
更新日期:2019-01-01 00:00:00
abstract::Water is a substance essential for life. It creates the environment of our body, keeps it's homeostasis, enables every biochemical reaction and metabolic processes in human organism. Maternal hydratation is essential for homeostasis of two organisms and drinking water influences the amniotic fluid volume, fetal well-b...
journal_title:Ginekologia polska
pub_type: 指南,杂志文章,实务指引
doi:
更新日期:2009-07-01 00:00:00
abstract::Authors had retrospectively analyzed basic exponents of perinatal care of 256 pregnant diabetic woman in years 1993-1998 hospitalized and delivered in Clinic of Obstetrics and Gynaecology in the town of Bytom. Our results were very similar to the other of Referent Centres Of Technical Methods Bank Used in Diagnostic a...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2002-12-01 00:00:00
abstract::The author describes the experiences and observations of 80 women with the Spider Cu, a Polish IUD. The Spider Cu is a copperbearing spatial IUD which demonstrates high elasticity, resilience, as well as a low pregnancy rate. (author's modified) ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1983-10-01 00:00:00
abstract::Among 64 women undergoing tubal-ovarian surgery 40.6% became pregnant spontaneously. Because of 47% of the remainder patients demonstrated anovulation the induction of ovulation was performed except the cases with hypergonadotrophic hypogonadism (9.4%). After treatment the total population with ovulatory cycles increa...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract:PURPOSE:This study is aimed to determine the clinical significance of echogenic amniotic fluid. MATERIAL AND METHODS:I surveyed 9 at term pregnancies in which the amniotic fluid was echogenic. Morphologic characteristics of amniotic fluid were assessed from samples taken at amniocentesis or upon delivery within one da...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2002-02-01 00:00:00
abstract::The system of cervical carcinoma prophylaxis introduced in 1974 in the Province of Szczecin based on obligatory obtaining of cytological smears at least one in a year from each woman coming for gynaecological examination and obligatory presentation of the result of this examination by each woman going for sanatorium t...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1989-07-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章,评审
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更新日期:2011-07-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2014-09-01 00:00:00
abstract::The group of 277 girls treated for vulvovaginitis was investigated. Any objective and subjective factors, which could effect on occurrence of this disease at girls were analysed. Over 2/3 of investigated girls were before menarche, 36.5% were 3-7 years old. Over 30% had urinary tract infections, 10%--tonsillitis. No e...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1993-07-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.a2017.0058
更新日期:2017-01-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.17772/gp/57844
更新日期:2015-10-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:1995-07-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:10.17772/gp/1904
更新日期:2015-01-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2010-07-01 00:00:00
abstract::During menopausal transition not only ovarian production of estrogens but also marked decrease of adrenal androgen production are observed Decreased secretion of adrenal DHEA and DHEA-S result in reduction of peripheral conversion of these steroids into active estrogens and androgens. Intracrinology describes the bios...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2011-09-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2011-11-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.17772/gp/1623
更新日期:2013-08-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2015-04-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVES:There are some data concerning homocysteine influence on fertilization and early embryogenesis, especially in women experiencing recurrent pregnancy loss (RSA). However, limited data support hypothesis that the ovum might be exposed to high homocysteine concentration what may be important in egg-sperm intera...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2003-09-01 00:00:00
abstract::Freezing of the human embryos has been routinely used in the world for over 10 years in the treatment of infertility by the ART. Excessive fertilized oocytes and embryos can be frozen and preserved in the temperature of liquid nitrogen. The risk of multiple pregnancies is reduced and enhancement of pregnancy rates can...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:1996-05-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2010-01-01 00:00:00