Abstract:
OBJECTIVES:There are some data concerning homocysteine influence on fertilization and early embryogenesis, especially in women experiencing recurrent pregnancy loss (RSA). However, limited data support hypothesis that the ovum might be exposed to high homocysteine concentration what may be important in egg-sperm interactions, for example during in vitro-fertilization (IVF) cycle. DESIGN:Therefore, the aim of our study was to determine fasting total homocysteine concentration in follicular fluid or serum of women experiencing reproductive failure after spontaneous or in-vitro fertilization. MATERIALS AND METHODS:Eight nonpregnant RSA women, 8 normal healthy women with previous successful pregnancy outcome and 15 women undergoing IVF (6 with unexplained infertility-UI, 6 with male factor-MF, 3 with tubal obstruction-TO). Total fasting homocysteine level concentrations were established by ELISA method (Axis Homocysteine EIA, Axis-Shield AS) in serum of RSA and normal healthy women or ovarian follicular fluid of women undergoing IVF. RESULTS:Mean fasting total homocysteine concentration in study group were as follows: RSA-18.63 mumol/L +/- 6.67, Normal-13.98 mumol/L +/- 6.62, UI-20.62 mumol/L +/- 8.19, MF-22.60 mumol/L +/- 7.87, TO-36.75 mumol/L +/- 13.26. We found that RSA women have had significantly higher serum homocysteine concentration when compared to normal healthy women (P < 0.05). Among women undergoing IVF, those with following IVF success had not significantly lower homocysteine level when compared to those with IVF failure (22.81 mumol/L +/- 11.27 vs. 24.54 mumol/L +/- 9.50, P > 0.05). CONCLUSIONS:Our preliminary data suggest that high homocysteine level may negatively influence pregnancy outcome following natural or in-vitro fertilization. It cannot be excluded that elevated homocysteine concentrations contribute to defective chorionic villous vascularization during early stages of gestation.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Jerzak M,Putowski L,Baranowski Wkeywords:
subject
Has Abstractpub_date
2003-09-01 00:00:00pages
949-52issue
9eissn
0017-0011issn
2543-6767journal_volume
74pub_type
杂志文章abstract:OBJECTIVE:To establish the normal range of embryonic heart rate (EHR) and foetal heart rate (FHR) at 6(+0) to 11(+6) weeks of gestation, to evaluate the risk of pregnancy loss depending on EHR and FHR values and to establish if checking of FHR with the use of M-mode method is possible in different levels obstetric depa...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVES:This study was conducted in order to produce translation, cultural adaptation, and validation of Assessment of Pelvic Floor Disorders and Their Risk Factors During Pregnancy and Postpartum Questionnaire (APFDQ) to Turkish in pregnant and postpartum population. MATERIAL AND METHODS:The study included 80 preg...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.2020.0072
更新日期:2020-01-01 00:00:00
abstract::EPH-gestosis is accompanied by an extensive remodelling of the extracellular matrix of the umbilical cord arteries, vein and Wharton's jelly. For better understanding of processes proceeding in it we decided to determine proteolytic activity in acidic pH range. Presented results suggest that cathepsin D is one of the ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2000-08-01 00:00:00
abstract::Scientific journals are ranked and evaluated to measure their relative importance and influence on science within a specific field. One of the tools most widely used to evaluate and compare journals is the Thomson Reuters Impact Factor In Poland a specific value of a scientist's Impact Factor is required for academic ...
journal_title:Ginekologia polska
pub_type: 社论
doi:
更新日期:2011-08-01 00:00:00
abstract:INTRODUCTION:The aim of the paper was to evaluate the usability of nucleated blood cells count in newborn infants in the first 12 hours after their birth as an early marker of intraventricular haemorrhage. MATERIAL AND METHODS:The retrospective research included 210 newborns (both born at term??? and prematurely), del...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to evaluate hormonal contraception use in women with epilepsy and to assess the risk of potential interactions between contraceptives and antiepileptic drugs (AEDs). MATERIAL AND METHODS:Data on hormonal contraception were obtained prospectively in women of childbearing age treated ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.2019.0010
更新日期:2019-01-01 00:00:00
abstract::Selected clinical features of the course of pregnancy in 118 gravidas with placenta praevia diagnosed ultrasonographically on the first breeding were compared. The clinical features significantly connected with bleeding and the prognostic features for the way of delivery were stated. The longest bleeding was observed ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract::We analysed the indications to myomectomy in females in reproductive age and estimated efficasy of this treatment. 112 patients aged 23-45 were analysed. Most common indication to this procedure were: menorrhagia--45.54%, myoma found at gynecological examination--21.43%, adnexal mass--20.54% and pelvic pain--15.18%. 5...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract:OBJECTIVES:The aim of the following study was to assess antisperm antibodies in sera samples of infertile men and women, as well as from prepubertal boys by means of flow cytometry. MATERIAL AND METHODS:We tested sera samples of infertile and fertile adult populations, prepubertal boys with gonadal disorders and healt...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2010-08-01 00:00:00
abstract::We present a case of a 65 year-old woman with a late vesicovaginal fistula after colporrhaphy. Too late proper diagnosis of that complication caused perivesical tissue inflammation and led to damage to the urinary bladder, occlusion of the urethra as well as created a massive inflammatory tumor in the minor pelvis, wh...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::Water is a substance essential for life. It creates the environment of our body, keeps it's homeostasis, enables every biochemical reaction and metabolic processes in human organism. Maternal hydratation is essential for homeostasis of two organisms and drinking water influences the amniotic fluid volume, fetal well-b...
journal_title:Ginekologia polska
pub_type: 指南,杂志文章,实务指引
doi:
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVES:Therapeutic hypothermia TH became broadly used in the management of the asphyxiated newborns. Although two cooling methods are used, so far the superiority of none of them has been established. The purpose of the study is to compare two cooling methods: selective head cooling (SHC) and whole body cooling (WB...
journal_title:Ginekologia polska
pub_type: 杂志文章,多中心研究
doi:10.5603/GP.2019.0069
更新日期:2019-01-01 00:00:00
abstract::Multiple pregnancies are considered high risk. This qualification is associated with the multitude of conditions which are known to complicated these pregnancies. Early diagnosis of these complications is the fundamental element of clinical managements. In numerous cases therapeutic protocols are widely known and in m...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2000-11-01 00:00:00
abstract::Some given sex hormones in patients treated due to marital infertility in this paper is analysed. Testosterone, prolactin, FSH and LH were examined. Males with sperm pattern showing evident pathology into our study were chosen: azoospermia, severe oligospermia, kryptozoospermia. ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract::We examined peritoneal fluid obtained during laparoscopy in the aspect of its influence on cytotoxic activity of NK cells. We showed significant suppression of this activity in women with unexplained infertility. The suppression of NK activity was also present in women fertile and infertile both, with severe endometri...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1998-12-01 00:00:00
abstract:OBJECTIVES:Due to hormonal changes during the menopause, women experience a variety of perimenopause and postmenopause symptoms. This review examines the various aspects of nanostructured hormone therapy and its application in the treatments of menopausal symptoms. MATERIAL AND METHODS:Excerpta Medica DataBase, Medica...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:10.5603/GP.a2017.0018
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:Comparison of the ability to inhibit alloactivated lymphocytes proliferation of human Wharton Jelly (WJ) and amniotic membrane (AM) mesenchymal stem cells (MSCs) from preterm and term pregnancies. MATERIAL AND METHODS:Term-WJ-MSCs (n = 5) and Preterm-WJ-MSCs (n = 1) were obtained from tissue explants by adh...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.a2017.0037
更新日期:2017-01-01 00:00:00
abstract::Uterine arteriovenous malformations are uncommon but potentially life-threatening condition. They can be congenital or acquired and should be suspected in cases of severe or persistent uterine bleeding. In recent years, there has been an increasing number of reports of acquired vascular lesions of the uterus following...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.a2018.0039
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:Literature describing complications after colposuspension and analyses of the learning curve is scarce. Knowledge concerning this topic may lower the frequency of complications, improve the effectiveness of the procedure and increase patients' satisfaction. DESIGN:The purpose of the study was to evaluate ty...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2007-04-01 00:00:00
abstract::The influence of hormone replacement therapy (HRT) on coagulation system has not been completely explained yet. We measured plasma activities of antithrombin III, protein C and protein S before and after 6 and 12 months of HRT in 48 postmenopausal women. HRT consisted of transdermal estradiol and orally medroxyprogest...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract::Two cases of unilateral urethral obstruction caused by endometriosis were reported. Two patients aged 48 and 35 years old were fully diagnosed with above mentioned abnormalities prior to a surgical operation. During the surgical operations the initial diagnosis was confirmed macroscopically, followed by the surgical a...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVES:The aim was to present pregnancy complications and outcome in the group of women with subchorionic hematoma (SCH) diagnosed in the first or second trimester of pregnancy METHODS:A retrospective study was performed to compare the perinatal outcome of 41 patients with SCH (study group) with 59 women treated o...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2010-12-01 00:00:00
abstract::Seventh caesarean section in the same pregnant woman was described. Pregnancy was terminated in 36 week of gestation cause of preterm uterine activity, after getting pulmonary maturation and estimating ultrasound fetal weight over three kilograms. The caesarean section and postoperative period were uncomplicated. Ther...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract::The term hypertension in pregnancy stands either for a high blood pressure, which has already developed before pregnancy (i.e., chronic hypertension in pregnancy), or for a pregnancy-associated disease (i.e., pregnancy-induced hypertension). Each form of hypertension may be an isolated phenomenon or constitute a part ...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2002-09-01 00:00:00
abstract::The are shown the expediency of prophylactic antibiotics administration during cesarean section. The investigations contained 32 pregnant women who were given intravenously augmentin in dose of 1.2 g. The control group was made from 31 pregnant women who do not received antibiotic. In both group cesarean section was p...
journal_title:Ginekologia polska
pub_type: 临床试验,杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::We report a case of a 6-week cervical pregnancy successfully treated with systemic methotrexate and gestational sac biopsy with 15%-calcium chloride solution injection. Serial monitoring of human chorionic gonadotropin levels, combined with ultrasound examinations, confirmed spontaneous miscarriage. Applied treatment ...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVES:Intrahepatic cholestasis in pregnancy (ICP) is a pregnancy-specific liver disorder. Its etiology is not fully understood. Increasing evidence indicates the important role of vitamin D and the vitamin D receptor (VDR) in this disorder. The presence of polymorphic variants in the VDR gene could influence its a...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.a2020.0135
更新日期:2020-01-01 00:00:00
abstract::We have analysed 6 cases of twin pregnancies with vertex presentation of the first foetus. In this cases after delivery of the first twin by vaginal route caesarean, section was made. Caesarean section of the second twin was made because of: transversal presentation with fetal distress syndrom (four cases), umbilical ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract::Childhood and adolescent gynecology is an emerging specialty at the intersection of pediatrics, pediatric endocrinology gynecology pediatric surgery dermatology psychiatry, public health medicine and genetics, and in fact addresses many legal issues. Poland lacks a uniform standing of medical and legal environments on...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:10.17772/gp/1553
更新日期:2013-02-01 00:00:00
abstract::12 male rabbits were administered cyproterone acetate in a dose of 20 mg/kg every 24 hours for the course of 28 days. Typochemical investigations were then carried out on the relative contents of histone and DNA, using the cytophotometric method. The spermatozoid content of DNA was analyzed using the Feulgen stainin...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1975-09-01 00:00:00