Abstract：
OBJECTIVES:Comparison of the ability to inhibit alloactivated lymphocytes proliferation of human Wharton Jelly (WJ) and amniotic membrane (AM) mesenchymal stem cells (MSCs) from preterm and term pregnancies. MATERIAL AND METHODS:Term-WJ-MSCs (n = 5) and Preterm-WJ-MSCs (n = 1) were obtained from tissue explants by adherent method. Term-AM-MSCs (n = 5) and Preterm-AM-MSCs (n = 1) were obtained by tripsin and collagenase digestion method. Term and Preterm MSCs phenotype was confirmed in vitro by flow cytometry. To evaluate the potential of fetal and adult MSCs to diminish immunological response mixed lymphocytes reaction (MLR) has been performed. RESULTS:Term and Preterm cells were positively identified as MSCs by the expression of CD73 and CD90 and CD105 with simultaneous absence of CD11b, CD14, CD19, CD34, CD45 and HLA-DR. The mean inhibition of allostimulated lymphocytes after addition of fetal derived MSCs amounted 64.8% for term AM-MSCs and 42.1% for term WJ-MSCs (for both populations the effect was statistically significant, p < 0.01). The addition of preterm-MSCs to MLR resulted in reduction of stimulated lymphocytes proliferation by 64.9% for AM-MSCs and 86.1% for WJ-MSCs. CONCLUSIONS:Presented results suggest that preterm fetal tissues contain MSCs which posses similar immunosuppressive capacity as those from term pregnancies. In the future MSCs from the umbilical cord and amnion can be potentially used to prevent immuno-dependent injuries in premature newborns.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Dąbrowski FA,Burdzinska A,Kulesza A,Kaleta B,Pączek L,Wielgoś Mdoi
10.5603/GP.a2017.0037subject
Has Abstractpub_date
2017-01-01 00:00:00pages
191-197issue
4eissn
0017-0011issn
2543-6767pii
VM/OJS/J/50615journal_volume
88pub_type
杂志文章abstract：:The expert panel recommendations are issued in order to increase the number of patients with urinary incontinence and overactive bladder receiving appropriate care. The expert panel recommends that urologists, gynecologists and other physicians interested in the field of incontinence should Incontinence question shoul...
journal_title：Ginekologia polska
pub_type： 杂志文章,实务指引
doi：
更新日期：2010-10-01 00:00:00
abstract：:Theoretically, a woman could bear unlimited number of fetuses. Practically, the human being on the top of his phylogenetic spread, has chosen the singleton birth as its dominant. The anatomical constitution of the woman let her feed no more than two children at the same time. This were probably the reasons for conside...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2004-11-01 00:00:00
abstract：OBJECTIVES:Overexpression of intracellular adhesion molecule-I (ICAM-1) was observed in many benign and malignant tumors. The aim of our study was to evaluate its serum concentrations as well as CA-125 in women with benign ovarian tumors. MATERIALS AND METHODS:Forty-five women treated surgically because of benign ovar...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-10-01 00:00:00
abstract：:Four cases of young women with Wilson's disease who underwent liver transplantation are presented. The menstrual disturbances associated with Wilson's disease are presented and discussed. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：INTRODUCTION:Ectopic pregnancy may lead to massive haemorrhage, infertility or death. Prompt diagnosis and treatment are crucial to save patients who would otherwise die. Serum amylase and lipase measurements are known biochemical markers of pancreatic inflammation and a recognized finding that may help diagnose acute ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2009-05-01 00:00:00
abstract：:Fetal face is the key anatomical location, both psychologically and clinically for the mother and the clinician. Ultrasound prenatal examination of the maxillofacial region allows to evaluate the fetal face in the first weeks of gestation. In ambulatory intravaginal ultrasound, sensitivity of the facial defect detecti...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.17772/gp/1643
更新日期：2013-09-01 00:00:00
abstract：:Gestational diabetes mellitus (GDM) is a common complication of pregnancy In the course of pregnancy elevated levels of hormones and other proteins having insulin-antagonistic effects lead to higher insulin resistance in peripheral tissues, followed by hyperinsulinemia. Risk factors for the development of GDM have bee...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.17772/gp/2429
更新日期：2015-05-01 00:00:00
abstract：OBJECTIVES:The aim of the following work was to evaluate vaginal and cervical colonization in patients with threatening preterm labor and comparing the frequency of colonization of the term and preterm labor groups. MATERIAL AND METHODS:532 pregnant women with threatening preterm labor were included into the clinical ...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to assess the treatment options and survival of uterine cervical cancer (UCC) patients who develop isolated pulmonary metastases (IPM) and to establish risk factors for IPM. MATERIAL AND METHODS:Data from patients diagnosed with UCC between June 1991 and January 2017 at the Gynecol...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2018.0102
更新日期：2018-01-01 00:00:00
abstract：:The author describes the experiences and observations of 80 women with the Spider Cu, a Polish IUD. The Spider Cu is a copperbearing spatial IUD which demonstrates high elasticity, resilience, as well as a low pregnancy rate. (author's modified) ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1983-10-01 00:00:00
abstract：OBJECTIVE:The aim of the study was an evaluation of the frequency and distribution of congenital malformations in infants born at the Obstetrics and Gynecology Department of Wołomin District Hospital in the years 1991-95 and 2000-2004 and a comparison of occurrence frequency of defects' types in the analyzed periods. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-09-01 00:00:00
abstract：:The study presents the frequency of occurrence of newborn haemolitic disease caused by Rh (D) system incompatibility in the years 1980-1999. Serological incompatibility prophylaxis was introduced in 1980. Routine use of anti-D immunoglobulin has led to a significant reduction in the number of newborns with haemalitic ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：UNLABELLED:Studies on fetal lung/brain circulation by means of power Doppler technique have suggested a marked reduction in lung perfusion in high-risk pregnancies as a sign of circulation redistribution. The ratio between lung/brain perfusion might therefore give a new method to predict fetal circulation centralizatio...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1686
更新日期：2014-01-01 00:00:00
abstract：:Concentrations of iron, zinc and copper were determined in public hair of women with threatened abortion and in full-term pregnancy. The aim of the studies was to find differences between the levels of studied elements in public hair of women with threatened abortion and in full-term pregnancy and to test whether pari...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-07-01 00:00:00
abstract：OBJECTIVES AND DESIGN:The aim of this study was retrospective analysis of ultrasound and echocardiographic examinations in fetuses with diagnosis of posterior urethral valve, at the referral center from the database of our unit in 8 years (1994-2002). RESULTS AND CONCLUSIONS:Among 8525 ultrasound and echocardiography ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to determine whether anhydramnios affected the duration of medical abortion in cases with various indications as compared to cases with normal amniotic fluid volume. MATERIAL AND METHODS:Patients who were admitted to our clinic because of medical abortion between January 2010-Decemb...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2016.0058
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVES:Therapeutic hypothermia TH became broadly used in the management of the asphyxiated newborns. Although two cooling methods are used, so far the superiority of none of them has been established. The purpose of the study is to compare two cooling methods: selective head cooling (SHC) and whole body cooling (WB...
journal_title：Ginekologia polska
pub_type： 杂志文章,多中心研究
doi：10.5603/GP.2019.0069
更新日期：2019-01-01 00:00:00
abstract：:The knowledge of ovarian physiopathology and the employing of modern diagnostic methods (ultrasonography, laparoscopy) allow to avoid to operate patients with functional cysts. Girls and young women should be evaluated individually for ovarian surgical procedures. The operative treatment should be so conservative as p...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：OBJECTIVES:The ultrasound-guided transversus abdominis plane (TAP) block is a supporting method of pain relief after different types of surgical and gynecological procedures. The aim of the present study was to evaluate the analgesic effects of the TAP-block in patients undergoing caesarean section. MATERIAL AND METHO...
journal_title：Ginekologia polska
pub_type： 杂志文章,随机对照试验
doi：10.5603/GP.a2018.0072
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to evaluate hormonal contraception use in women with epilepsy and to assess the risk of potential interactions between contraceptives and antiepileptic drugs (AEDs). MATERIAL AND METHODS:Data on hormonal contraception were obtained prospectively in women of childbearing age treated ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2019.0010
更新日期：2019-01-01 00:00:00
abstract：:Conditions under which episodes of eclampsia occurred in puerperal, who were than admitted to the Intensive Care Units for treatment are presentation the paper. Multidirectional diagnostic procedures introduced in those 30 patients are discussed. In the analysed group of patients various types of organ complications w...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：OBJECTIVES:The etiology of intrahepatic cholestasis of pregnancy (ICP) involves environmental, hormonal and genetic factors. It is thought that ICP may be related to the polymorphic variants of several genes involved in the metabolism and transport of bile acids (BA). The goal of our study was to evaluate the possible ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2018.0067
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVES:The objective of this study was to determine the maternal PLAC1 protein levels in early and late onset preec-lampsia. MATERIAL AND METHODS:A total of 135 pregnant women were included in the study, of which 55 were at < 34 weeks of gesta-tion and 80 were at ≥ 34 weeks of gestation, between June and November ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2018.0025
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Angiogenesis is of crucial importance for endometrial tumor growth and Vascular Endothelial Growth Factor (VEGF) is the key mediator of angiogenesis. OBJECTIVE:The purpose of our study was to assess the prognostic value of VEGF and its receptors in relation to endometrioid endometrial carcinomas. MATERIAL ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2010-06-01 00:00:00
abstract：:A group of 15 women between the ages of 24-45 were given intraamiotic does of 40 mg of prostagladin F2alpha (PGF2alpha; Enzaprost) in a single dose so as to terminate pregnancy. These pregnancies, between the 15th- 24th weeks, were terminated for medical reasons. 12 hours elapsed between the time of intraamniotic ad...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1988-09-01 00:00:00
abstract：OBJECTIVES:The aim of our study was clinical analysis of patients operated with squamous cell carcinoma of the uterine cervix. MATERIALS AND METHODS:Between 1972 and 1991 at the 2nd Department of Obstetrics and Gynecology Medical University of Gdańsk 687 total hysterectomies in Wertheim-Meigs method were performed in ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-02-01 00:00:00
abstract：OBJECTIVES:The study aimed to assess the associations between circulating vaspin levels and nutritional status (assessed on tha basis of BMI) as well as insulin resistance in PCOS. MATERIAL AND METHODS:Eighty-seven PCOS women, 48 obese and 39 normal weight, were enrolled in the cross-sectional study. Seventy-two Non-P...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2020.0056
更新日期：2020-01-01 00:00:00
abstract：:Paper concerns 293 laparoscopic operations. The most frequent types of laparoscopic operations in presented material were: adhesion lysis in minor pelvis (33.8% cases), cystectomy and cyst-ovariectomy (27.6%) and electrocoagulation of ovarian capsule. Operative laparoscopy because of small injury is useful method in t...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：OBJECTIVES:This article describes the most frequent reasons, complications and appropriate treatment of pregnancy with uterine myomas and pregnancy after the myomectomy. MATERIALS AND METHODS:It is the analysis of pregnancies and deliveries of 24 women hospitalised in Medical Academy of Gdańsk. RESULTS:The typical co...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2002-04-01 00:00:00
abstract：:During menopausal transition not only ovarian production of estrogens but also marked decrease of adrenal androgen production are observed Decreased secretion of adrenal DHEA and DHEA-S result in reduction of peripheral conversion of these steroids into active estrogens and androgens. Intracrinology describes the bios...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2011-09-01 00:00:00
