Abstract：
OBJECTIVES:The objective of this study was to determine the maternal PLAC1 protein levels in early and late onset preec-lampsia. MATERIAL AND METHODS:A total of 135 pregnant women were included in the study, of which 55 were at < 34 weeks of gesta-tion and 80 were at ≥ 34 weeks of gestation, between June and November 2014 were recruited in this case control study. RESULTS:Analysis of maternal serum PLAC1 levels did not reveal any significant differences between early onset PE and controls (p = 0.422). However, late onset PE patients exhibited significantly elevated levels of PLAC1, in comparison with healthy controls (p = 0.026). The difference in PLAC1 levels between early onset PE and late onset PE was also significant (p = 0.001). Area under ROC curve of PLAC1 for early and late onset PE was 0.563 and 0.646 with p values of 0.422 and 0.026 respectively. Area under ROC curve of PLAC1 in PE was 0.613 with p value = 0.024. The cutoff value for PLAC1 was 6.19 ng/mL with sensitivity: 56% (95% CI 44.1-67.3) and specificity: 63 %; (95% CI 49.9-75.1) and diagnostic odds ratio: 2.2 (95% CI 1.1-4.4) (p value = 0.037). The cutoff value for PLAC1 was 7.2 ng/mL with sensitivity: 43% (95% CI 31.5-54.6) and specificity: 78% (95% CI 65.5-87.5) and diagnostic odds ratio: 2.69 (95% CI 1.25-5.79) (p value = 0.016) CONCLUSION: In conclusion, the results of the current study showed that PLAC1 protein levels were significantly elevated in pregnant women with late onset PE in comparison with healthy control group.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Ibanoglu MC,Ozgu-Erdinc AS,Uygur Ddoi
10.5603/GP.a2018.0025subject
Has Abstractpub_date
2018-01-01 00:00:00pages
147-152issue
3eissn
0017-0011issn
2543-6767pii
VM/OJS/J/56679journal_volume
89pub_type
杂志文章abstract：:We present a case of vaginal vault prolapse after hysterectomy associated with cystocoele with central and lateral defect and stress urinary incontinence, that was treated surgically with employment of sacrospinous colpopexy through anterior approach (from paravesical space), combined with anterior colporrhaphy by dou...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
abstract：OBJECTIVES:It is controversial whether pelvic organ prolapse and stress urinary incontinence (SUI) should be treated simultaneously with a single surgery or separately with two procedures. The pre-pubic four-arm NAZCA-TC® mesh was invented to treat cystocele and SUI with a single procedure. The objective of this study ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2017.0105
更新日期：2017-01-01 00:00:00
abstract：:Osteoporosis is a great problem in postmenopausal women. It begins 4--5 years after a last period and appears in clinical form in about 25-44% women. Basic irregularity is osteopenia as a result of bone resorption superiority. Many observations lead to conclusion that postmenopausal osteoporosis follows estrogens defi...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:We present a case of a 65 year-old woman with a late vesicovaginal fistula after colporrhaphy. Too late proper diagnosis of that complication caused perivesical tissue inflammation and led to damage to the urinary bladder, occlusion of the urethra as well as created a massive inflammatory tumor in the minor pelvis, wh...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：DESIGN:Neonatal hypoxia is often responsible for myocardial ischaemia. To evaluate cardiac involvement in neonates, fetal and neonatal ECG recordings have been performed and parameters indicating heart dysfunction have been analysed. OBJECTIVES:Our interest has been focused on analysis of fetal electrocardiogram recor...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-11-01 00:00:00
abstract：AIM OF THE PAPER:Comparison of conventional cytodiagnostics with molecular identification of DNA and mRNA HPV HR, immunocytochemical test for suppressor protein P16 and nuclear Ki 67 to detect cervical pathology screening of the division to LG SIL and HG SIL. MATERIAL:630 Pap smears were taken from women with suspecte...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2012-12-01 00:00:00
abstract：INTRODUCTION:Ectopic pregnancy (EP) is usually located in the Fallopian tube and it has a significant adverse effect on womens fertility Three types of EP treatment include: expectant, medical, and surgical radical (salpingectomy) or conservative (salpingotomy) management. OBJECTIVES:The aim of the study was to compar...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1675
更新日期：2013-12-01 00:00:00
abstract：:Ovarian cancer remains to be a real challenge in spite of considerable progress in many areas of modern medicine. The use of genetic testing for detecting mutations of the BRCA genes has been offering clinical scrutiny between mutated versions of the BRCA genes and higher risk of both breast and ovarian cancer A popul...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2012-01-01 00:00:00
abstract：:The aim of the study was estimation of endocrinological function of placenta in pregnancy complicated by GDM. The study were performed on a group 13 women with GDM and 14 women in normal pregnancy. All women with GDM were treat by diet and intensive insulinotherapy with self monitoring levels of glucose. In women with...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：DESIGN:The aim of our study was a currently clinical analysis of menarche. MATERIALS AND METHODS:The mean age of menarche was investigated in 4497 girls between 1975-1997 69 girls were examined throughly in the course of menarche. Age at menarche, body weight, height, body mass index (BMI), some of the hormones and ul...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
abstract：:In this paper the fibronectin gene expression level (Northern blotting) in 33 endometrial samples (residua post abortum, endometrium proliferativum, secretivum and involutivum, hyperplasia glandularis endometrii, adenocarcinoma endometrii) was measured and compared. Higher level of fibronectin gene expression level in...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1995-08-01 00:00:00
abstract：:576 patients with preterm deliveries that occurred between the 22nd to 37th gestation weeks were undergone clinical analysis. The material was collected in the years 1995 to 1999 at Clinic of Obstetric and Perinatology of Pomeranian Academy of Medicine in Szczecin. In our study the rate of preterm delivery was 10.5%. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to test the relationship between maternal serum proinflammatory cytokines level and AFI (amniotic fluid index) in pregnancies complicated by premature rupture of membranes (PROM). MATERIALS AND METHODS:The maternal serum levels of IL-6, IL-1 beta and TNF-alfa were assessed in patient...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：:Among micro-organisms infecting vagina whose dominant genus is GV anaerobic bacteria are often present. There are reports that GV infections of vagina and uterine cervix, apart from their well-known negative role in obstetrics practice can play a role in carcinogenic processes of uterine cervix. The aim of the study w...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：:The opioid system modulates the growth and development of CNS. Hypoxia increases endogenous opioids significantly. The density and distribution of mu-opioid receptors in MPOA is cyclical and sexually dimorphic. To test the hypothesis that perinatal hypoxia affects the development of the opioid receptor system in fetus...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：:9.98% of all gynecological surgical interventions made at the Clinic in Zabrez from 1965 to 1971 were for ectopic pregnancy. 157 cases of ectopic pregnancy were chosen at random for clinical analysis. Microscopic examinations of the excised oviduct were made in order to establish the cause of tubular implantation. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1975-06-01 00:00:00
abstract：:Cyclopia is a deformation of the facial skeleton with one eye orbit formed in the place where both eyes should be present. As a result of hypoplasia there is absence (hypothesized loss) of central nervous system structures. Teratogenic factors leading to the occurrence of this anomaly may include irregular cholesterol...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVES:The aim of the following work was to evaluate vaginal and cervical colonization in patients with threatening preterm labor and comparing the frequency of colonization of the term and preterm labor groups. MATERIAL AND METHODS:532 pregnant women with threatening preterm labor were included into the clinical ...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2010-11-01 00:00:00
abstract：:Multiple pregnancies are considered high risk. This qualification is associated with the multitude of conditions which are known to complicated these pregnancies. Early diagnosis of these complications is the fundamental element of clinical managements. In numerous cases therapeutic protocols are widely known and in m...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2000-11-01 00:00:00
abstract：AIM:To evaluate the a-chemokine stromal cell-derived factor-1 (SDF-1)/CXCL12 levels in the peritoneal fluid (PF) and plasma of patients with epithelial ovarian cancer (EOC, n=101), serous cyst (n=34) or normal controls (n=20). SDF-1alpha concentrations were correlated to myeloid (M) and lymphoid (L) dendritic cells (DC...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2011-06-01 00:00:00
abstract：OBJECTIVE:Retrospective clinical and pathomorphological analysis of patients undergoing surgery due to endometrial carcinoma; analysis of the correlation between histological grading of endometrial cancer and selected pathomorphological results. MATERIAL AND METHODS:Statistical analysis was based on the pathomorpholog...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/2419
更新日期：2015-05-01 00:00:00
abstract：CASE REPORT:A 48-year-old woman with acute urinary retention due to a big cervical leiomyoma pressing on the urethra was admitted to the Gynecologic Unit. A Foley catheterization was performed and 1500 mL of urine was drained. The gynecologic examination revealed a cervical tumor 10 cm in diameter. Acute urinary retent...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.17772/gp/1904
更新日期：2015-01-01 00:00:00
abstract：:Presented patient was many times admitted to gynaecological wards and surgically treated with irreversible results. The complaints were mainly related to specific psychological disturbances. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1996-02-01 00:00:00
abstract：:Two patients aged 35 i 40 years after extensive clinical evaluation were operated by means of combined approach--laparoscopy and vaginal resection of endometriotic tumors. First laparoscopy was performed in order to dissect rectovaginal septum and separate rectum from the vagina in order to facilitate complete vaginal...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVES:The aim of the paper was to assess nasal and oral amniotic fluid flows, with the use of color ultrasound and spectral Doppler, in normal fetuses. MATERIAL AND METHODS:Forty-six fetuses of singleton gestations were studied prospectively. Spectrum imaging and maximal nasal fluid flow velocities were described...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2018.0054
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVES:Triplet pregnancies have higher perinatal morbidity and mortality rates than singleton pregnancies. In modern perinatology computer cardiotocography is one of the best methods of fetus state assessment. DESIGN:The research was based on computer analysis of cardiotocograph printouts. MATERIALS AND METHODS:T...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-10-01 00:00:00
abstract：:The purpose of the study was to estimate blood flow in uterine arteries in patients with uterus cervix invasive carcinoma. In the study the colour Doppler ultrasonography was used. It was found out that in the group of patients with uterus cervix carcinoma pulsation index (PI)--1.82 +/- 1.44 as well as resistance inde...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：:One of the mechanisms for direct cell to cell signaling is mediated by gap junctions. These junctions are formed by connexins, transmembrane proteins. Gap junction intercellular communication (GJIC) plays a critical role in tissue development, differentiation of cells, and regulation of tissue homeostasis. Cancer cell...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVES:The aim was to present pregnancy complications and outcome in the group of women with subchorionic hematoma (SCH) diagnosed in the first or second trimester of pregnancy METHODS:A retrospective study was performed to compare the perinatal outcome of 41 patients with SCH (study group) with 59 women treated o...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2010-12-01 00:00:00
abstract：OBJECTIVES:There are some data concerning homocysteine influence on fertilization and early embryogenesis, especially in women experiencing recurrent pregnancy loss (RSA). However, limited data support hypothesis that the ovum might be exposed to high homocysteine concentration what may be important in egg-sperm intera...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
