Abstract：
OBJECTIVES:The study aimed to assess the associations between circulating vaspin levels and nutritional status (assessed on tha basis of BMI) as well as insulin resistance in PCOS. MATERIAL AND METHODS:Eighty-seven PCOS women, 48 obese and 39 normal weight, were enrolled in the cross-sectional study. Seventy-two Non-PCOS women, 41 obese and 31 normal weight, constituted a control group. Body mass, height and waist circumference as well as body composition by bioimpedance were measured. In the morning (16h after the last meal) we determined: serum glucose, insulin, androgens, gonadotropin (LH, FSH) and sex hormone-binding globulin (SHBG) as well as plasma vaspin levels. Standard HOMA-IR formula was used to assess insulin resistance (IR). RESULTS:Plasma vaspin levels were significantly lower in PCOS, both normal weight and obese, than in Non-PCOS groups. Vaspin levels were similar in normal weight and obese PCOS subgroups. There was no association between plasma vaspin levels and anthropometric parameters in PCOS group. While in Non-PCOS group a negative correlation between plasma vaspin levels and body mass (r = -0.26; p < 0.05) was found. We did not observe correlations between plasma vaspin levels and serum glucose and insulin concentrations as well as HOMA-IR values, however, in multivariable, stepwise backward regression waist circumference and HOMA-IR values explained 18.0% of plasma vaspin levels variability in the study subjects. CONCLUSIONS:PCOS occurrence is associated with decreased vaspin levels. The influence of nutritional status on vaspin level observed in Non-PCOS is abolished in PCOS women, possibly by more severe insulin resistance.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Franik G,Plinta R,Madej P,Owczarek A,Bozentowicz-Wikarek M,Chudek J,Skrzypulec-Plinta V,Olszanecka-Glinianowicz Mdoi
10.5603/GP.2020.0056subject
Has Abstractpub_date
2020-01-01 00:00:00pages
251-255issue
5eissn
0017-0011issn
2543-6767pii
VM/OJS/J/65082journal_volume
91pub_type
杂志文章abstract：:The aim of study was the evaluation of generating the IL-10 by peripheral blood lymphocytes in women with endometriosis according to the stage of of the disease. Cytokine was estimated by immunoenzymatic method Elisa. The generation of IL-10 by peripheral blood lymphocytes was lower in patients with all stages of endo...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-05-01 00:00:00
abstract：:The study presents the frequency of occurrence of newborn haemolitic disease caused by Rh (D) system incompatibility in the years 1980-1999. Serological incompatibility prophylaxis was introduced in 1980. Routine use of anti-D immunoglobulin has led to a significant reduction in the number of newborns with haemalitic ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：:The stromal Leydig cell tumour (SLCT), a very rare, benign neoplasm was described in 75-year old woman. The patient presented the typical signs of virilisation (hirsutism, masculine alopecia, moderate clitoris enlargement, deep voice) as well as hypertension and insulin independent type of diabetes mellitus (IIDM). Ad...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the clinical utility of CA-125 measurements in peritoneal fluid (PF) as an indicator of endometriosis. DESIGN:CA-125 levels in paired serum and peritoneal fluid were assessed by IMx CA-125 Assay (ABBOTT). PATIENTS:107 women with and without endometriosis, undergoing laparoscopy during the luteal...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVES:The study was designed to evaluate the effectiveness of cervical cancer prophylactics by identification of the time of last cervical cytological examination as well as by recognition of frequency of repeated cervical cytological examinations and reimbursement for the examination costs in representative sampl...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2005-11-01 00:00:00
abstract：UNLABELLED:The aim of the study was to analyze life-threatening conditions of the premature neonates who required hospitalization in The Neonatal Intensive Care Unit (NICU). Postnatal mortality was also taken into consideration. MATERIAL AND METHODS:The study group consisted of the neonates born prematurely in the Obs...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
abstract：:The expert panel recommendations are issued in order to increase the number of patients with urinary incontinence and overactive bladder receiving appropriate care. The expert panel recommends that urologists, gynecologists and other physicians interested in the field of incontinence should Incontinence question shoul...
journal_title：Ginekologia polska
pub_type： 杂志文章,实务指引
doi：
更新日期：2010-10-01 00:00:00
abstract：:Ovarian cancer remains to be a real challenge in spite of considerable progress in many areas of modern medicine. The use of genetic testing for detecting mutations of the BRCA genes has been offering clinical scrutiny between mutated versions of the BRCA genes and higher risk of both breast and ovarian cancer A popul...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2012-01-01 00:00:00
abstract：INTRODUCTION:Most of preIntroduction: Most pregnancies after assisted reproduction techniques are dizygotic twin gestations. There is a close relationship between the development and functioning of the placenta and the growth of both fetuses in dizygotic twin pregnancies. Angiogenesis is the process of creating new cap...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1663
更新日期：2013-11-01 00:00:00
abstract：:Thrombotic thrombocytopenic purpura (TTP) is characterized by microangiopathic hemolytic anemia and thrombocytopenia, accompanied by microvascular thrombosis that causes variable degrees of tissue ischemia and infarction. About 10-20% of TTP cases are associated with the pregnancy. Preterm delivery and intrauterine fe...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2008-07-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to determine serum concentrations of a proinflammatory cytokine, tumor necrosis factor-alpha (TNF-α), in patients with recurrent abortions undergoing treatment with sildenafil or etanercept. MATERIAL AND METHODS:Serum TNF-α concentrations were determined for 24 patients with recurre...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/57823
更新日期：2015-07-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVES:To analyzed the therapeutic results for patients with overlooked iatrogenic ureteral injuries after gynecological surgery, treated at the department since 1990. Before the era of endourology, ureteral injuries were operated on immediately after making a diagnosis. This approach was changed after the populari...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2016.0069
更新日期：2016-01-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.5603/GP.a2018.0088
更新日期：2018-01-01 00:00:00
abstract：:Sensibility and specificity of transvaginal ultrasonography and diagnostic hysteroscopy were compared in 211 infertile women. Examinations were performed between 1996-2000 in I-st Department of Obstetrics and Gynecology Warsaw Medical University--Poland. Comparing results we concluded high compatibility of transvagina...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：:The group of 277 girls treated for vulvovaginitis was investigated. Any objective and subjective factors, which could effect on occurrence of this disease at girls were analysed. Over 2/3 of investigated girls were before menarche, 36.5% were 3-7 years old. Over 30% had urinary tract infections, 10%--tonsillitis. No e...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：OBJECTIVES:In recent years, much attention has been given to infants born prematurely, at 34 0/7 to 36 6/7 weeks of gestation (WG), which have been classified as 'late preterm'. Neonates from that subgroup are less physiologically and metabolically mature than term infants. The aim of the study was to determine whether...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2016.0092
更新日期：2016-01-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2007-04-01 00:00:00
abstract：:Bacterial infection is a major cause of neonatal morbidity and mortality. The increased susceptibility of the neonate especially premature one, for bacterial infection is the result of several factors including a delayed maturation of immune response of neonatal B and T cells and deficiencies of the myelopoetic system...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2005-01-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1975-03-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2007-11-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-08-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2005-04-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-04-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
