Abstract:
:Gestational diabetes (GDM) is defined as a glucose intolerance of varying severity with onset or first recognition during pregnancy. Two major metabolic disorders: insulin resistance and β-cells dysfunction, play currently major role in pathogenesis of GDM. Adipose tissue is an organ involved in production of adipokines, which have various influence on metabolism of glucose and lipids. Visfatin is an adipokine mainly produced and secreted by the fat tissue. It exerts an insulin-like effect by binding to the insulin receptor-1 and have hypoglycemic effect. Visfatin appears to be an important factor in the pathophysiology of GDM. The aim of this article is to review the literature concerning the relationship between the adipokine mentioned above and GDM, and to clarify its role in the pathophysiology of GDM.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Radzicka S,Pietryga M,Iciek R,Brązert Jdoi
10.5603/GP.a2018.0088subject
Has Abstractpub_date
2018-01-01 00:00:00pages
518-521issue
9eissn
0017-0011issn
2543-6767pii
VM/OJS/J/58984journal_volume
89pub_type
杂志文章,评审abstract::The authors studied a sensory intensity response to sodium chloride (NaCl) and a sensory hedonic response to salt in suprathreshold concentrations in 120 healthy primigravidas (age: 20-40) during three trimesters of physiological pregnancy, and in 22 healthy nonpregnant women of the same age examined on the 7th or 8th...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1998-04-01 00:00:00
abstract::A case of a 30 years old pregnant woman suffering from bilateral ovary tumour was presented. When she was sixteen weeks pregnant she had both tumours enucleated using the method of laparoscopy. Diagnostic and therapeutic process have been described. Authors are convinced that laparoscopy as a method of treatment can b...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2005-05-01 00:00:00
abstract:UNLABELLED:Homocysteine (HCY) is an amino acid being a methionin catabolite. The action of HCY is multi-directional and not yet fully known. Follicular fluid also contains homocysteine. Disorders of the composition of follicular fluid as an microenvironment of an oocyte may influence its development. AIM:The aim of ou...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2003-10-01 00:00:00
abstract::Endometrial cancer is one of the most frequently diagnosed malignant neoplasms among women. In Poland, it is in the fourth place in terms of incidence. The highest morbidity concerns women aged 50-70 years, however it may also appear in women in their reproductive period. Endometrial cancer concerns about 3% of premen...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVES:The two functions of the lower urinary tract are the filling/storage and emptying. Similarly lower urinary tract symptoms can be subdivided. DESIGN:The aim of the study was the estimation of usefulness of present complaints-voiding history in diagnosis of lower urinary tract dysfunctions. MATERIAL AND METH...
journal_title:Ginekologia polska
pub_type: 临床试验,杂志文章
doi:
更新日期:2001-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the outcomes of treatment in patients suffering from recurrent spontaneous abortion and antiphospholipid syndrome. MATERIALS AND METHODS:148 observed women suffering from recurrent abortion with presence of lupus anticoagulant antibodies (LA) and/or high moderate concentration of anticardiolipin ...
journal_title:Ginekologia polska
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to develop an optimal educational model for contraceptive counseling, to analyze conditions influencing choice of hormonal contraception, to study patients' opinions on present, planned and proposed contraceptive methods and to link these data with socioeconomic and demographic condi...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2012-06-01 00:00:00
abstract::Mammography can detect various types of calcification in the breast. Their correct estimation enables detection of the breast cancer in situ. In our research there have been analyzed various types of calcification available on radiograms, which have been placed in publications. The aim was to find out which of them co...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:1996-07-01 00:00:00
abstract::We present a case report of a 37-year-old woman with accidental finding of two IUDs--one inserted correctly and the other one located in the abdomen. ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to investigate to what extent sweeping of the membranes contributes to cervical shortening and if cervical shortening is related to the time to onset of labor and duration of the active phase of labor METHODS:This prospective randomized clinical trial was performed at Baskent Univer...
journal_title:Ginekologia polska
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2014-09-01 00:00:00
abstract::Bladder Pain Syndrome remains a great challenge for urologists, both in diagnostics and treatment. Etiopathogenesis of the disease is unknown. It is reported that the reason for Bladder Pain Syndrome is the urothelium dysfunction resulting in the destruction of the protective glycosaminoglycan layer/barrier protecting...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2011-03-01 00:00:00
abstract::A retrospective study about frequency of occurrence of endometrial adenocarcinoma in postmenopausal women which are associated with diabetes mellitus, overweight and hypertension was performed. The aim of the study was to have risk factors for carcinoma of endometrium estimated. The nonparametric statistics such as: 2...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1997-08-01 00:00:00
abstract::Gene therapy is an innovative way of treating genetic disorders, which enables removal or repair of genetic defects. Strategies of gene therapy offer new perspectives in treating cancer diseases. Numerous methods for specifically removing tumor cells are currently used. They can be divided into five main strategies: c...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:Surgical site infection (SSI) following gynecologic oncology surgery is a severe problem for both patient and surgeon in terms of increasing morbidity, length of hospital stay, anxiety, and costs. In this prospective, randomized, controlled study we investigated the effect of subcutaneous rifampicin and povi...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.a2020.0134
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:Endometrial carcinoma is a common malignancy of the female genital tract. There is a strong correlation between myometrial invasion and clinical prognosis. Increasing myometrial penetration is associated with an increasing risk of pelvic and para-aortic lymph node metastasis, adnexal metastasis, positive p...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2010-07-01 00:00:00
abstract::Criminal Law Codification Commission, acting at the Ministry of Justice prepared proposals for amendments in the Polish Penal Code, related to offenses against life and health that were presented to the public in 2013. The draft provides for the protection of the child in the prenatal stage, introducing a new category...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.17772/gp/59562
更新日期:2015-10-01 00:00:00
abstract::Family history of ovarian cancer has been regarded as the most important risk factor in developing this type of tumor. Recent identification of cloning of specific tumor suppressor genes responsible for hereditary ovarian cancer syndromes, resulted in the surge of enthusiasm and optimism regarding the practical applic...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2003-07-01 00:00:00
abstract:INTRODUCTION:Nowadays, mid-urethral slings are considered the gold standard in surgical treatment of female stress urinary incontinence (SUI). Traditionally this technique has been followed by short inpatient hospitalization and convalescence. From the perspective of both, the patient and the physician, this technique ...
journal_title:Ginekologia polska
pub_type: 临床试验,杂志文章
doi:10.17772/gp/1909
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:Gestational diabetes mellitus is a carbohydrate intolerance that occurs during pregnancy. Various inflammatory mediators are considered to be risk factors leading to GDM development. Among them are pro-inflammatory cytokines, such as IL16 and IL18. The aim of this study was to examine the association between...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.a2017.0047
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:Ovarian inhibins (INH) are hormones participating in the regulation of gametogenesis. We monitored inhibin A and B levels in serum (S) and follicular fluids (FF), depending on the type of fertility failure and treatment outcome. MATERIAL AND METHODS:We examined INHA and B levels in S and FF of 72 women under...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.17772/gp/57844
更新日期:2015-10-01 00:00:00
abstract::Osteoporosis is a great problem in postmenopausal women. It begins 4--5 years after a last period and appears in clinical form in about 25-44% women. Basic irregularity is osteopenia as a result of bone resorption superiority. Many observations lead to conclusion that postmenopausal osteoporosis follows estrogens defi...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:Angiopoietin-related growth factor (AGF) is associated with angiogenesis but it can also affect glucose and energy metabolism. The aim of the study was to determine AGF levels in gestational diabetes mellitus (GDM). MATERIALS AND METHODS:The study included 44 patients with GDM (GDM group) and 33 non-diabetic...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:Ki67 and PCNA proteins are characteristic for cells in mitotic cycle and represent unfavourable prognostic indices. Intensity of the proteins expression directly correlates with grade of tumour differentiation. They belong to the second category of prognostic factors in breast cancer according to the College...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::The concentration of N-terminal propeptide of type III procollagen (PIIINP) in umbilical cord serum was estimated in preterm and term newborns. The mean concentration of PIIINP was significantly higher in preterm infants, despite their lower body mass. This indicates higher rate of collagen biosynthesis in early gesta...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to evaluate the concentrations of kynurenic acid (KYNA) in blood and urine during the normal pregnancy. MATERIALS AND METHODS:Under the study were 37 pregnant women. Level of KYNA was measured by high performance liquid chromatography (HPLC). RESULTS:The KYNA concentration in blood...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1998-12-01 00:00:00
abstract:INTRODUCTION:Perinatal hysterectomy (PH) is usually a life-saving procedure, which is performed after all conservative treatment options fail. The PH frequency rate ranges from 0.04 to 0.23%. The most frequent indications for this procedure include: abnormal placental implantation, placenta previa, uterine rupture and ...
journal_title:Ginekologia polska
pub_type: 临床试验,杂志文章
doi:10.17772/gp/1712
更新日期:2014-03-01 00:00:00
abstract::Women have three very important physiological functions that are not observed in men--menstruation, pregnancy and lactation. Each of these mechanisms influences pharmacokinetics and pharmacodynamics of many drugs. Individualization of pharmacotherapy is a major challenge of modern medicine. The differences in response...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:10.17772/gp/2002
更新日期:2015-02-01 00:00:00
abstract::26 patients out of 48 (54%) with an advanced ovarian carcinoma (III and IV degree) treated in the first stage by means of Adriablastine, Cisplatin and Cyclophosphamide responded to the therapy. Complete remission was achieved in 24 patients (50%), and partial remission (PR) only in 2 patients. Four patients with CR in...
journal_title:Ginekologia polska
pub_type: 临床试验,杂志文章
doi:
更新日期:1989-02-01 00:00:00
abstract:INTRODUCTION:Vascular-cellular adhesion molecule-1 (VCAM-1) overexpression on the cells' surface is stimulated by pro-inflammatory cytokines, bacterial endotoxins, reactive oxygen species and lipid peroxides. In the serum also the soluble form of VCAM-1 (sVCAM-1) is present. The beta 1-integrin family molecule VLA-4 (C...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2003-10-01 00:00:00
abstract:INTRODUCTION:Placenta increta refers to the placenta invading the myometrium. It is a rare but life-threatening condition. The incidence of placenta increta ranges widely from 1 in 540 to 1 in 93,000 deliveries; in Poland it is approximately 0.2% of all deliveries. The occurrence of placenta praevia increta is much low...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2011-06-01 00:00:00