Abstract：
UNLABELLED:Preeclampsia is one of the most frequent and dangerous complications of a pregnancy. In preeclamptic pregnancies the spiral arteries are not modified properly. Disturbed blood flow finally leads to hypoxia which is responsible for the dysfunction of the endothelium. Endothelial growth factor (VEGF) and placental growth factor (PIGF) play an important role in the angiogenesis and thus may participate in the pathomechanism of preeclampsia. AIM:The aim of our study was to estimate VEGF and PIGF level in serum of patients with preeclampsia. MATERIALS AND METHODS:The study comprised 25 gravidas with preeclampsia and a control group of 18 healthy gravidas. In 25 preeclamptic women the angiogenic factors levels were measured in the III trimester and in 7 of them in the II trimester. In the control group these parameters were assessed in both periods. Both factors were measured by commercial available ELISA KIT. RESULTS:PIGF concentrations were significantly (p < 0.0001) lower in sera of patients with preeclampsia in the II and III trimester in comparison to the controls: 17.4 vs. 290.3 pg/ml and 99.1 vs. 347.8 pg/ml, respectively. In most cases serum VEGF levels were undetectable. CONCLUSIONS:(1) PIGF is involved in the pathomechanism of preeclampsia and its maternal serum concentration decreases significantly in the course of the disease. (2) The sensitivity of the commercially available ELISA assay is too low to assess the serum VEGF concentration in women with preeclampsia.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Semczuk-Sikora A,Krzyzanowski A,Kwiatek M,Semczuk Msubject
Has Abstractpub_date
2007-11-01 00:00:00pages
873-6issue
11eissn
0017-0011issn
2543-6767journal_volume
78pub_type
杂志文章abstract：:The current knowledge concerning the fibrocystic disease of the breast is presented in this work. The authors outlined the theoretical principles of the problem and the most important diagnostic methods as well as the prophylaxis and prognostic in the fibrocystic disease of the breast. ...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：1993-01-01 00:00:00
abstract：:Cyclopia is a deformation of the facial skeleton with one eye orbit formed in the place where both eyes should be present. As a result of hypoplasia there is absence (hypothesized loss) of central nervous system structures. Teratogenic factors leading to the occurrence of this anomaly may include irregular cholesterol...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2011-03-01 00:00:00
abstract：INTRODUCTION:Ectopic pregnancy (EP) is usually located in the Fallopian tube and it has a significant adverse effect on womens fertility Three types of EP treatment include: expectant, medical, and surgical radical (salpingectomy) or conservative (salpingotomy) management. OBJECTIVES:The aim of the study was to compar...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1675
更新日期：2013-12-01 00:00:00
abstract：:Four cases of young women with Wilson's disease who underwent liver transplantation are presented. The menstrual disturbances associated with Wilson's disease are presented and discussed. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVE:To establish the normal range of embryonic heart rate (EHR) and foetal heart rate (FHR) at 6(+0) to 11(+6) weeks of gestation, to evaluate the risk of pregnancy loss depending on EHR and FHR values and to establish if checking of FHR with the use of M-mode method is possible in different levels obstetric depa...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2009-03-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to determine whether anhydramnios affected the duration of medical abortion in cases with various indications as compared to cases with normal amniotic fluid volume. MATERIAL AND METHODS:Patients who were admitted to our clinic because of medical abortion between January 2010-Decemb...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2016.0058
更新日期：2016-01-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2016.0031
更新日期：2016-01-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2013-10-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章,随机对照试验
doi：10.5603/GP.a2018.0072
更新日期：2018-01-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2018.0054
更新日期：2018-01-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVES:From a theoretical viewpoint, intraperitoneal therapy (i.p.) in-patients with ovarian cancer, a malignancy, which remains mainly, confined to the peritoneal cavity is logical. Intraperitoneal catheters have moved to the forefront as a delivery system in cancer treatment. Authors have described complications ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:The group of 100 men, divided into two groups according to WHO criteria concerning the spermatozoa content was evaluated. The group of 44 oligospermic and azoospermic men was compared with the control group consisting of 56 normospermic men by means of Mann-Whitney U. The statistically significant differences were est...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-06-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
abstract：:The group of 277 girls treated for vulvovaginitis was investigated. Any objective and subjective factors, which could effect on occurrence of this disease at girls were analysed. Over 2/3 of investigated girls were before menarche, 36.5% were 3-7 years old. Over 30% had urinary tract infections, 10%--tonsillitis. No e...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1778
更新日期：2014-08-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：1996-06-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：1999-03-01 00:00:00
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journal_title：Ginekologia polska
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doi：
更新日期：2000-08-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2004-12-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2019.0090
更新日期：2019-01-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章,评审
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更新日期：2019-01-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
