Abstract：
OBJECTIVE:The purpose of the study was to compare concentrations of inflammatory and Th1/Th2 cytokines in serum obtained from women with preeclampsia or severe pregnancy hypertension versus normotensive controls. MATERIAL AND METHODS:The study group consisted of 34 pregnant women with hypertension over 140/90mmHg and proteinuria over 0.3 g/day or severe pregnancy hypertension. 16 healthy pregnant women comprised the control group. The concentration of IL-2, IL-4, IL-6, IL-10, TNFalpha and IFNgamma was measured with Cytometric Bead Array Human Th1/Th2 Cytokine Kit II (Becton Dickinson). U-Mann Whitney test was used for the comparison of the results. RESULTS:We found statistically significantly increased concentrations of IFNgamma: 8.4 +/- 5.3 pg/ml vs. 4.2 +/- 3.2 pg/ml (p = 0.02), TNFalpha: 1.5 +/- 0.7 pg/ml vs. 0.7 +/- 0.3 pg/ml (p = 0.04) and IL-2: 1.3-0.6 pg/ml vs. 0.6 +/- 0.4 pg/ml (p = 0.01) in the studied group. The level of IL-6 35.5 +/- 21.0 pg/ml vs. 19.8 +/- 12.3 pg/ml was also increased but the difference did not reach statistical significance. Concentrations of IL-4 and IL- 10 were similar in both groups. CONCLUSION:Increased concentrations of Th1 cytokines (IFNgamma, IL-2) in the serum of women with preeclampsia suggests an exaggerated cytotoxic activity of blood in this pathology accompanied by an increase in the levels of inflammatory cytokines TNFalpha and IL-6.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Tarnowska-Madra U,Leibschang J,Kowalska B,Filipp E,Kozar A,Nimer A,Maciejewski Tsubject
Has Abstractpub_date
2010-03-01 00:00:00pages
192-6issue
3eissn
0017-0011issn
2543-6767journal_volume
81pub_type
杂志文章abstract：:Basic methods of contraception of unwanted pregnancy are reviewed: mechanical, vaginal devices, hormonal tablets, and IUDs. On the basis of personal experience the author considers that, compared with other methods of contraception, the intrauterine spiral is the safest device for the female organism. An evaluation...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1975-03-01 00:00:00
abstract：:127 pregnant patients between 20 and 37 week of gestation were studied. Cervical estimation was done by using transvaginal ultrasonography. An accurate estimation was possible in all investigation patients. Statistically significant distinctions in uterine cervical length during pregnancy progress were noticed (p < 0....
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-08-01 00:00:00
abstract：:Placental mesenchymal dysplasia (PMD) is a rare benign vascular anomaly of the placenta. It can be misdiagnosed as a molar pregnancy resulting in unnecessary termination of pregnancy. A 30-year-old woman was referred to our hospital at 18 gestational weeks due to suspicion of molar pregnancy. The ultrasound showed a b...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2020.0129
更新日期：2020-01-01 00:00:00
abstract：:The Impact Factor is a measure of average citation frequency for articles in a specific scientific journal during a specific period of time. IF takes into account the content, sources, layout and frequency and regularity of publishing. In order to get an impact factor, a journal needs to be first put on the Philadelph...
journal_title：Ginekologia polska
pub_type： 社论
doi：
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVES:The role of angiogenesis in leiomyosarcomas still remains unclear. The aim of this study was to evaluate the NRP1 expression in the leiomyosarcoma tissues and to find the relations between its expression and the clinical features. MATERIAL AND METHODS:The study group consisted of 50 patients with diagnosis ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2018.0002
更新日期：2018-01-01 00:00:00
abstract：:The authors evaluated the influence of NAD, NADP, G-6-P and G-6-PDH on the synthesis of steroid hormones in the interstitial gland of the rat. The animals were killed by decapitation, and sections of the nucleus weighing altogether 20 mg were incubated with NAD (0.4 mM), NADP (0.4 mM), G-6-P (3.5 mM) and G-6-PDH (2 j....
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1989-05-01 00:00:00
abstract：:An analysis of the fates of women after passed pregnancy was performed concerning the type of surgery and the microscopic findings in the excised oviducts. The analysis based on the subsequent frequency of intrauterine pregnancies in the operated subjects, incidence of repeat ectopic pregnancies and following sterilit...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：OBJECTIVES:The ultrasound-guided transversus abdominis plane (TAP) block is a supporting method of pain relief after different types of surgical and gynecological procedures. The aim of the present study was to evaluate the analgesic effects of the TAP-block in patients undergoing caesarean section. MATERIAL AND METHO...
journal_title：Ginekologia polska
pub_type： 杂志文章,随机对照试验
doi：10.5603/GP.a2018.0072
更新日期：2018-01-01 00:00:00
abstract：MATERIAL AND METHODS:It was a retrospective analysis of fetal echocardiography results (analysis of congenital heart defect (CHD) and functional abnormalities in normal heart anatomy) in 83 fetuses diagnosed and treated in the same institution. RESULTS:In our group of fetuses, the most common structural defect, in add...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:To investigate long-term postoperative outcomes of conservative and radical surgery in ectopic tubal pregnancies, and evaluate the results of these techniques. METHODS:A total of 145 patients that operated for tubal pregnancy between January 2006 and January 2009 were reviewed. Data on patient age, reproduct...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2012-04-01 00:00:00
abstract：UNLABELLED:The aim of the study was to evaluate antioxidant system activity and lipid peroxidations products as markers of oxidative stress in the cord blood of newborns delivered to mothers with diabetes type G1 in comparison to healthy pregnant women. MATERIALS AND METHODS:We examined 10 healthy and 10 diabetic moth...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：:The position of intrauterine devices (IUDs) was determined by means of ultrasonography in 68 women using Combison 200 Compound Soan ultrasonography 2 to 3 days after insertion of the IUD, after the next menstruation, and during examinations after 3 to 24 months. Pain, prolonged menstruation, and spotting between mens...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1984-09-01 00:00:00
abstract：OBJECTIVES:In our study, we tried to investigate the determinants of women's choices about contraception with the aim of discovering whether or not there is a difference in their preferences before and after consultation with a gynaecologist. MATERIAL AND METHODS:A total of 1058 women were enrolled. They were given de...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2017.0115
更新日期：2017-01-01 00:00:00
abstract：:An ability to fetal maturity prediction is particularly important in high risk pregnancies. A computer-aided ultrasonographic monitoring of pregnancy enables to assess an actual fetal maturity on the base on two or more ultrasound measurements. This paper presents a mathematical method of the actual fetal maturity eva...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:The aim of the work was the analysis of prenatal care in the region of Tarnobrzeg during the period 1976-1997, which was based on the statistical materials of the provincial outpatient department of Mother and Child in Tarnobrzeg. It was indicated that measuring of value factors of prenatal care on the basis of pregna...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：:In the serum of 21 women with malignant ovarian tumours, 13 with uterine myomas and 16 with cysts the concentrations were determined of alpha 1 inhibitor of proteases and alpha 2 macroglobulin by immunodiffusion, and the functional activity of both inhibitors which made possible calculation of the specific activity (u...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：INTRODUCTION:Perinatal hysterectomy (PH) is usually a life-saving procedure, which is performed after all conservative treatment options fail. The PH frequency rate ranges from 0.04 to 0.23%. The most frequent indications for this procedure include: abnormal placental implantation, placenta previa, uterine rupture and ...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：10.17772/gp/1712
更新日期：2014-03-01 00:00:00
abstract：:We present a case of vaginal vault prolapse after hysterectomy associated with cystocoele with central and lateral defect and stress urinary incontinence, that was treated surgically with employment of sacrospinous colpopexy through anterior approach (from paravesical space), combined with anterior colporrhaphy by dou...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
abstract：OBJECTIVES:Evaluate the time dependent expression of genes in preterm neonates and verify the influence of ontogenic maturation and the environmental factors on the gene expression after birth. MATERIAL AND METHODS:The study was carried out on 20 full-term newborns and 62 preterm newborns (mean birth weight = 1002 [g]...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2017.0080
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to determine the effect of hormone replacement therapy (oral and transdermal) on the erythrocyte antioxidant enzyme activity in postmenopausal women. DESIGN:Prospective clinical study. MATERIAL AND METHODS:The erythrocyte Cu/Zn superoxide dismutase activity was measured in 14 postme...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-04-01 00:00:00
abstract：:This study was performed in 52 women in their early postmenopausal period, divided into two equal groups. The control group included women with menopausal symptoms only, women in the study group demonstrated also pruritus. All women were on estrogen replacement therapy, additionally a bacterial auto-vaccine was admini...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:There have been many advances in perinatal medicine, but few as impressive as those in Rh-disease. Over several decades, we have seen a disease, which once caused the perinatal death of half of all Rh-immunized pregnancies, almost disappear. The success of this medical campaign should serve as a model for the conqueri...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：OBJECTIVES:The evaluation of sexual life after hysterectomy is still controversial. DESIGN:The aim of the study was to analyse the impact of hysterectomy on frequency and quality of the woman's sexual life. MATERIAL AND METHODS:The total of 539 women operated in II Department of Obstetrics and Gynecology in 1990-2000...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-07-01 00:00:00
abstract：OBJECTIVES:The purpose of our study was to determine maternal serum concentrations of IL-8, IL-6, IFN-gamma during normal pregnancy and labor. MATERIALS AND METHODS:Maternal serum IL-8, IL-6 and IFN-gamma levels were measured by means of ELISA technique in 41 healthy pregnant women in 22-42 week gestation and 15 healt...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the clinical utility of CA-125 measurements in peritoneal fluid (PF) as an indicator of endometriosis. DESIGN:CA-125 levels in paired serum and peritoneal fluid were assessed by IMx CA-125 Assay (ABBOTT). PATIENTS:107 women with and without endometriosis, undergoing laparoscopy during the luteal...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：DESIGN:Neonatal hypoxia is often responsible for myocardial ischaemia. To evaluate cardiac involvement in neonates, fetal and neonatal ECG recordings have been performed and parameters indicating heart dysfunction have been analysed. OBJECTIVES:Our interest has been focused on analysis of fetal electrocardiogram recor...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-11-01 00:00:00
abstract：OBJECTIVES:Osteoporosis is a multifactoral disease with aetiology depending from the hormonal, environmental, and genetic factors. One of the suggested candidate gene involved in the pathogenesis is the polymorphic gene encoding for vitamin D receptor (VDR). VDR polymorphism was connected with bone mineral density (BMD...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-05-01 00:00:00
abstract：:The purpose of the study was to present the symptoms, diagnostic methods, and treatment in retroperitoneal fibrosis (RPF). We present a case of a 53-year-old woman admitted to the hospital due to low back and abdominal pain complaints lasting a year. Ultrasonography revealed a myoma located along the right bank of the...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.17772/gp/60465
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:Angiopoietin-related growth factor (AGF) is associated with angiogenesis but it can also affect glucose and energy metabolism. The aim of the study was to determine AGF levels in gestational diabetes mellitus (GDM). MATERIALS AND METHODS:The study included 44 patients with GDM (GDM group) and 33 non-diabetic...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2012-10-01 00:00:00
abstract：:Transvaginal ultrasound scanning was performed on 59 years old women with postmenopausal bleeding in anamnesis. Endometrial thickness was measured at its maximum in both longitudinal and transverse sections of the uterus. Also the thickness of uterus walls and ovaries in 3 planes were measured. Endometrium was irregul...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
