[The role of gonadotropins, cyclic AMP, 22-R-hydroxycholesterol and cofactors in regulating endocrine functions of the Leydig cells in rats. I. Effect of cofactors on the synthesis of steroid hormones in the interstitial gland of rats].

Abstract:

:The authors evaluated the influence of NAD, NADP, G-6-P and G-6-PDH on the synthesis of steroid hormones in the interstitial gland of the rat. The animals were killed by decapitation, and sections of the nucleus weighing altogether 20 mg were incubated with NAD (0.4 mM), NADP (0.4 mM), G-6-P (3.5 mM) and G-6-PDH (2 j.m./ml) for 4 hours in CO2 incubator. Then the tissue was homogenized, removed by centrifugation and then from the homogenous supernatant the authors extracted steroids which were in the incubating medium and in the tissue. Steroid hormones examined were marked radioimmunologically, they were: pregnenolon as the first and testosterone as the second stage of synthesis of nucleus androgens. The search carried out shows that the strongest stimulator in biosynthesis of pregnenolon was NADP together with the reducing system (G-6-P and G-6-PDH). On the other hand, in case of testosterone the highest effectiveness was achieved by simultaneous use of the cofactors examined. Applying cofactors separately the authors were able to find that both NAD and NADP together with the reducing system were responsible for testosterone synthesis and their simultaneous applying in the incubating medium leads to a synergistic effect.

journal_name

Ginekol Pol

journal_title

Ginekologia polska

authors

Grochowski D,Szamatowicz M

subject

Has Abstract

pub_date

1989-05-01 00:00:00

pages

241-5

issue

5

eissn

0017-0011

issn

2543-6767

journal_volume

60

pub_type

杂志文章
  • Long-term outcomes of radical and conservative surgery for late diagnosed tubal pregnancies.

    abstract:OBJECTIVE:To investigate long-term postoperative outcomes of conservative and radical surgery in ectopic tubal pregnancies, and evaluate the results of these techniques. METHODS:A total of 145 patients that operated for tubal pregnancy between January 2006 and January 2009 were reviewed. Data on patient age, reproduct...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Ozler A,Turgut A,Evsen MS,Sak ME,Soydinç HE,Başaranoğlu S,Celik Y,Taner MZ

    更新日期:2012-04-01 00:00:00

  • [Correlation between the expression of mRNA of histones H2B and H4 and mRNA of kinin receptors B1 and B2 assessed by QRT-PCR in vulvar cancer].

    abstract:OBJECTIVES:Histones are involved in process of proliferation and differentiation of the cells. In many lesions the expression of mRNA of histones is a marker of proliferation. The expression of kinin receptors B1 and B2 coexist with inflammatory processes, but in some studies the expression of these receptors was found...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Olejek A,Mazurek U,Kuśmierz D,Michalska A,Wilczok T

    更新日期:2002-11-01 00:00:00

  • [Amniocentesis and amniotic infusion: benefits and risks].

    abstract::The introduction of the amnioinfusion technic in the treatment of chosen complications of pregnancy, requires an easy access to the amniotic cavity. Catheterisation of the amniotic cavity requires the skilled technic, and is not associated with the rise of the obstetrics complications. ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Heimrath J,Pajak J,Zalewski J,Kłósek A,Florjański J

    更新日期:1998-02-01 00:00:00

  • [The influence of perinatal risk factors on the number of CD3+ lymphocytes and CD25+ cells in full-term neonates].

    abstract::In 39 full-term neonates aged from 1 to 7 days of life, among them 24 with perinatal risk factors and 15 healthy as the control group, immunophenotyping of CD3+ and CD25+ cells using Becton Dickinson flow cytometer and monoclonal antibodies and CD3+ and CD25+ was performed. It was stated, that the mean relative and ab...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Ziecina-Krawiec B,Mazur B,Godula-Stuglik U,Stojewska M

    更新日期:2000-06-01 00:00:00

  • [Respiratory distress in newborns born to hypertensive mothers and acid-base equilibrium and the ion composition of the amniotic fluid].

    abstract::Twenty-five samples of amniotic fluid obtained by amniocentesis from 25 pregnant women with hypertension in the 35 to 40 weeks of pregnancy were studied. The following biochemical determinations were done in the samples: acid-base equilibrium (pH, pO2, pCO2, base deficit, standard HCO3- and total CO2), concentrations ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Wojcicka-Jagodzińska J,Kuczyńska-Sicińska J,Romejko E,Smolarczyk R,Szczecina R

    更新日期:1989-10-01 00:00:00

  • [Effect of immunotherapy on the level of immunoglobulin in serum of women with pruritus of the vulva].

    abstract::This study was performed in 52 women in their early postmenopausal period, divided into two equal groups. The control group included women with menopausal symptoms only, women in the study group demonstrated also pruritus. All women were on estrogen replacement therapy, additionally a bacterial auto-vaccine was admini...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Stanosz S,Sycz G,Borowiak M

    更新日期:1992-01-01 00:00:00

  • Effective treatment of cervical incompetence in a monochorionic monoamniotic twin pregnancy with a rescue cervical cerclage and pessary--a case report and review of literature.

    abstract::A monochorionic monoamniotic (MCMA) twin pregnancy is the rarest form of twin gestation, accounting for around 1:10000 to 1:20000 of all deliveries regardless of the region of the world. All multiple gestations have a higher risk of preterm delivery due to either preterm uterine contractions or asymptomatic cervical s...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Kosińska-Kaczyńska K,Szymusik I,Bomba-Opoń D,Brawura-Biskupski-Samaha R,Wegrzyn P,Wielgoś M

    更新日期:2012-12-01 00:00:00

  • Unusual case of adenomyosis of the uterine body with malignant clinical course.

    abstract::We report an unusual case of adenomyosis with asymptomatic thoracic endometriosis. A 30-year old woman had a history of nephroblastoma, two missed abortions and one childbirth by caesarean section. The pregnancy was complicated with asymmetric fetus hipotrophy. Two years after delivery she had assessments for dysmenor...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Rabczyński J,Neuberg M,Gerber J,Jeleń M,Kołodziej J

    更新日期:2003-01-01 00:00:00

  • [Nucleated red blood cells as an early marker of intraventricular haemorrhage in newborn infants].

    abstract:INTRODUCTION:The aim of the paper was to evaluate the usability of nucleated blood cells count in newborn infants in the first 12 hours after their birth as an early marker of intraventricular haemorrhage. MATERIAL AND METHODS:The retrospective research included 210 newborns (both born at term??? and prematurely), del...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Krajewski P,Kalinka J,Welfel E,Kwiatkowska M,Pokrzywnicka M

    更新日期:2007-12-01 00:00:00

  • Maternal placi protein levels in early- and late-onset preeclampsia.

    abstract:OBJECTIVES:The objective of this study was to determine the maternal PLAC1 protein levels in early and late onset preec-lampsia. MATERIAL AND METHODS:A total of 135 pregnant women were included in the study, of which 55 were at < 34 weeks of gesta-tion and 80 were at ≥ 34 weeks of gestation, between June and November ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.a2018.0025

    authors: Ibanoglu MC,Ozgu-Erdinc AS,Uygur D

    更新日期:2018-01-01 00:00:00

  • [Myomas and pregnancy--obstetrics dilemma of the next decade?].

    abstract:OBJECTIVES:This article describes the most frequent reasons, complications and appropriate treatment of pregnancy with uterine myomas and pregnancy after the myomectomy. MATERIALS AND METHODS:It is the analysis of pregnancies and deliveries of 24 women hospitalised in Medical Academy of Gdańsk. RESULTS:The typical co...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Kulikowska-Ciecielag K,Płoszyński A,Damdinsuren A,Leszczyńska K,Mielnik J

    更新日期:2002-04-01 00:00:00

  • [Laparoscopy in clinical practice. II. Usefulness in diagnosis of sterility].

    abstract::The paper presents results of 1099 laparoscopies performed in sterility. Laparoscopy was made in the second phase of the menstrual cycle, 5 to 7 days after probable ovulation, as a last stage in diagnosis of sterility. Normal state of genital organs and minor pelvis was noted in 20.9% of investigated patients. In the ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Blecharz A,Rzempołuch J,Horak S,Szustak J,Wolf A,Kruk M

    更新日期:1993-04-01 00:00:00

  • The analgesic efficiency of transversus abdominis plane (TAP) block after caesarean delivery.

    abstract:OBJECTIVES:The ultrasound-guided transversus abdominis plane (TAP) block is a supporting method of pain relief after different types of surgical and gynecological procedures. The aim of the present study was to evaluate the analgesic effects of the TAP-block in patients undergoing caesarean section. MATERIAL AND METHO...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,随机对照试验

    doi:10.5603/GP.a2018.0072

    authors: Kupiec A,Zwierzchowski J,Kowal-Janicka J,Goździk W,Fuchs T,Pomorski M,Zimmer M,Kübler A

    更新日期:2018-01-01 00:00:00

  • [Pregnancy course in women with terminal kidney failure treated with hemodialysis].

    abstract::According to the European Dialysis and Transplantation Association at least 250 patients on each 1 million of inhabitants in Europe is treated with renal replacement therapy. One can assumed that if only half of above mentioned are women then from 5 to 10 of them can conceive pregnant. It's likely that number of pregn...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Gumprecht J,Gumprecht K,Monsiol A,Grzeszczak W

    更新日期:1995-07-01 00:00:00

  • [Diagnostic micro-laparoscopy in gynecology].

    abstract::Diagnostic microlaparoscopy was performed on 30 patients aged 17-41. Indications++ for these procedures were: sterility (17), tumor of the ovary (5), endometriosis (3), uterine myoma (2), pelvic pain syndrome++ (1), carcinoma of the ovary--second look procedures (1), operative hysteroscopy (1). During these procedures...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Obrzut B,Skret A,Kluz T

    更新日期:1999-08-01 00:00:00

  • [Bladder pain syndrome--an urological-gynecological problem].

    abstract::Bladder Pain Syndrome remains a great challenge for urologists, both in diagnostics and treatment. Etiopathogenesis of the disease is unknown. It is reported that the reason for Bladder Pain Syndrome is the urothelium dysfunction resulting in the destruction of the protective glycosaminoglycan layer/barrier protecting...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Zabkowski T,Bortnowski L,Zieliński H

    更新日期:2011-03-01 00:00:00

  • [Fetal echocardiography in fetal ovarian cysts].

    abstract:OBJECTIVES:The aim of the study was to evaluate the outcome of fetuses with ovarian cysts in relation to fetal echocardiography. MATERIAL AND METHODS:In the Department for Diagnosis and Prophylaxis of Birth Defects at the Polish Mother's Memorial Hospital in Lodz fetal echocardiography was performed in 21 fetuses with...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Słodki M,Janiak K,Szaflik K,Wilczyński J,Oszukowski P,Chilarski A,Respondek-Liberska M

    更新日期:2008-05-01 00:00:00

  • [Analysis of risk factors for nosocomial infections in the Neonatal Intensive Care Unit of the Pomeranian Medical University in Szczecin in the years 2005-2008].

    abstract:UNLABELLED:The aim of the study was to assess the significance of some perinatal risk factors and neonatal complications in occurrence of nosocomial infections in the population of NICU patients. MATERIAL AND METHODS:Analysis of risk factors was performed in all patients treated in the years 2005-2008 in NICU Departme...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Elster T,Beata Czeszyńska M,Sochaczewska D,Konefał H,Baryła-Pankiewicz E

    更新日期:2009-08-01 00:00:00

  • [New molecular methods in prenatal invasive diagnostics].

    abstract::New diagnostic techniques employed in laboratories all over the world enable to create new tests for prenatal genetic diagnosis. They include cytogenetics, molecular-cytogenetics and molecular methods. Chromosomal numerical aberrations (aneuploidies) remain to be the most frequent genetic changes diagnosed prenatally ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Łaczmańska I,Stembalska A

    更新日期:2013-10-01 00:00:00

  • [Cord blood insulin and erythropoietin levels in relation to the mode of delivery].

    abstract:UNLABELLED:The aim of the study was evaluation, whether cord blood insulin (Ic) and erythropoietin (EPO) levels differ in accordance with mode of delivery: cesarean section (CS) or vaginal delivery (VD). MATERIAL AND METHODS:The study was performed in the diabetic group consisted of 148 newborns of diabetic mothers (N...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Czeszyńska MB,Ronin-Walknowska E

    更新日期:1999-10-01 00:00:00

  • Prediction of short-term newborn infectious morbidity based on maternal characteristics in patients with PPROM and Ureaplasma species infection.

    abstract:OBJECTIVES:Preterm premature rupture of membranes (PPROM) complicates about 5% of pregnancies. Ureaplasma species is the most common pathogen found in the amniotic fluid in pregnancieneonatal outcome. The aim of the following study was to evaluate the impact of colonization with the Ureaplasma spp. on pregnant women wi...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.17772/gp/57857

    authors: Mikołajczyk M,Wirstlein PK,Wróbel M,Mazela J,Chojnacka K,Skrzypezak J

    更新日期:2015-09-01 00:00:00

  • [Analysis of prenatal care in the Tarnobrzeg region between 1976-1997].

    abstract::The aim of the work was the analysis of prenatal care in the region of Tarnobrzeg during the period 1976-1997, which was based on the statistical materials of the provincial outpatient department of Mother and Child in Tarnobrzeg. It was indicated that measuring of value factors of prenatal care on the basis of pregna...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Dziamba A

    更新日期:1998-12-01 00:00:00

  • [Selected polymorphisms of Renin-Angiotensin System in the pathology of hypertensive disorders of pregnancy].

    abstract::Pregnancy induced hypertension and pre-eclampsia, defined as hypertension and proteinuria after 20 weeks of pregnancy with no history of such symptoms, are a great challenge in the field of perinatology They are a serious threat to the mother and the child. Regardless of numerous studies on the subject, the pathogenes...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:10.17772/gp/1566

    authors: Kuśmierska-Urban K,Rytlewski K,Reroń A

    更新日期:2013-03-01 00:00:00

  • [Stromal sarcoma of the uterus in an 18-year old girl].

    abstract::The authors describe diagnostic difficulties connected with proper estimation of stromal sarcoma biological activities, which developed in uterus corpus in 18 year old girl previously treated with hormones, because of irregular painful menses. Macroscopic and microscopic investigations of postoperative specimen allowe...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Rabczyński J,Rzeszutko W,Kornafel J

    更新日期:1998-01-01 00:00:00

  • [Results of clomiphene citrate ovarian stimulation vs laparoscopic electrocoagulation of the ovaries in infertile women with PCOS].

    abstract:OBJECTIVE:To assess the results of clomiphene citrate ovarian stimulation vs laparoscopic electrocoagulation of the ovaries in infertile women with PCOS. DESIGN:47 women with PCOS were included into the study. 25 of them had ovarian stimulation using clomiphene citrate (100 mg for 5 consecutive days, during 6 cycle) a...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Grzechocińska B,Fracki S,Marianowski L

    更新日期:2000-09-01 00:00:00

  • [Electroresectoscopy in submucous fibroids, intrauterine adhesions and uterine malformation treatment].

    abstract::182 hysteroscopic operations with electroresectoscope use performed in Ist Department of Obstetrics and Gynaecology (Warsaw) between 1996-1999 were analyzed. Myomectomy was performed in 117 patients, resection of uterine septum in 25 and deliberation of intrauterine adhesions in 40 patients. Abnormal bleeding and infe...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Szymański R,Kamiński P,Marianowski L

    更新日期:2000-09-01 00:00:00

  • [Diagnostic methods for fetal malformations in the first half of pregnancy].

    abstract:INTRODUCTION:Fetal abnormalities are the most common cause of perinatal and postnatal death and infant handicap. For this reason prenatal screening (for fetal malformation) has become a routine part of obstetric care in many countries. Most often used are biochemical tests and continuously developing ultrasound diagnos...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Sieroszewski P,Suzin J,Baś-Budecka E

    更新日期:2003-10-01 00:00:00

  • [Assisted reproductive medicine in Poland, 2011--SPiN PTG report].

    abstract:AIM:The aim of this report is to present data concerning results and complications related to infertility treatment using assisted reproductive technology (ART) and insemination (IUI) in Poland in 2011. MATERIALS AND METHODS:The report was prepared by the Fertility and Sterility Special Interest Group of the Polish Gy...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.17772/gp/1770

    authors: Janicka A,Spaczyński RZ,Kurzawa R

    更新日期:2014-07-01 00:00:00

  • The role of insulin and selected adipocytokines in patients with polycystic ovary syndrome (PCOS) - a literature review.

    abstract::Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. It is manifested by hyperandrogenism, polycystic ovaries on ultrasound, oligomenorrhoea and anovulation. PCOS patients are more vulnerable to metabolic disorders: insulin resistance, obesity endothelium dysfunction, athero...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Ozegowska KE,Pawelczyk LA

    更新日期:2015-04-01 00:00:00

  • [Evaluation of some neutrophil adhesion molecules in pregnancy complicated by diabetes mellitus type 1].

    abstract:UNLABELLED:The effective functions of human peripheral blood neutrophil are modulated by regulatory molecules depending on receptor agonists and adhesion molecules. OBJECTIVES:Evaluation of percentage of neutrophil adhesion molecules in pregnancy of diabetic mothers as well as their expression on peripheral blood neut...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Pertyńska MP,Banasik M,Tchórzewski H,Cypryk K,Wilczyński J

    更新日期:2000-06-01 00:00:00