[Maternal serum cytokines concentrations during normal pregnancy and labor].

Abstract:

OBJECTIVES:The purpose of our study was to determine maternal serum concentrations of IL-8, IL-6, IFN-gamma during normal pregnancy and labor. MATERIALS AND METHODS:Maternal serum IL-8, IL-6 and IFN-gamma levels were measured by means of ELISA technique in 41 healthy pregnant women in 22-42 week gestation and 15 healthy women in labor at term. All newborns and afterbirths had no signs of infection. RESULTS:IL-8 values for pregnant women ranged from 1.98 to 35.2 pg/ml with the median value 10.24 pg/ml, and the 95th percentile 24.5 pg/ml. IL-8 values for women in labor at term ranged from 3.96 to 54.8 pg/ml with the median 10.4 pg/ml. No statistically significant changes in serum IL-8 concentration were observed during pregnancy or in labor. Serum IL-6 concentrations in pregnant women ranged from 0 to 21.7 pg/ml with the median value 0 pg/ml, and the 95th percentile 15.5 pg/ml. Serum IL-6 concentrations in women in labor at term were significantly higher (p < 0.05): ranged from 0 to 39.2 pg/ml with the median 10.1 pg/ml and 95-th percentile 33.5 pg/ml. Maternal serum IFN-gamma concentrations in pregnant women ranged from 0 to 9.8 pg/ml with the median value 3.9 pg/ml, the 95th percentile 9.2 pg/ml and didn't differ during labor at term: range from 0 to 14.5 pg/ml, median 1.9 pg/ml. CONCLUSIONS:Our data revealed that maternal serum IL-8 concentrations didn't changed during the course of pregnancy and in labor. Women in labor had significantly elevated serum IL-6 concentrations compared to those in pregnancy. We didn't observed such changes in serum IFN-gamma levels.

journal_name

Ginekol Pol

journal_title

Ginekologia polska

authors

Nowak M,Oszukowski P,Szpakowski M,Małafiej E,Malinowski A,Wieczorek A,Wierzbicka E,Drzazga W

keywords:

subject

Has Abstract

pub_date

1998-12-01 00:00:00

pages

1283-7

issue

12

eissn

0017-0011

issn

2543-6767

journal_volume

69

pub_type

杂志文章
  • [Three dimensional sonography and 3D power angiography in differentiation of adnexal tumors].

    abstract:BACKGROUND:Three-dimensional sonography is a novel diagnostic method proposed to be an additional non-invasive tool in the assessment of ovarian tumors. OBJECTIVE:To study diagnostic potential of 3D sonography and power Doppler angiography in the preoperative differentiation of adnexal masses. MATERIAL AND METHODS:On...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Czekierdowski A,Smoleń A,Bednarek W,Kotarski J

    更新日期:2002-11-01 00:00:00

  • [Analysis of prenatal care in the Tarnobrzeg region between 1976-1997].

    abstract::The aim of the work was the analysis of prenatal care in the region of Tarnobrzeg during the period 1976-1997, which was based on the statistical materials of the provincial outpatient department of Mother and Child in Tarnobrzeg. It was indicated that measuring of value factors of prenatal care on the basis of pregna...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Dziamba A

    更新日期:1998-12-01 00:00:00

  • [Gap junction intercellular communication in carcinogenesis of endometrial cancer].

    abstract::One of the mechanisms for direct cell to cell signaling is mediated by gap junctions. These junctions are formed by connexins, transmembrane proteins. Gap junction intercellular communication (GJIC) plays a critical role in tissue development, differentiation of cells, and regulation of tissue homeostasis. Cancer cell...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Baltaziak M,Kańczuga-Koda L,Rutkowski R,Musiatowicz M,Koda M,Leśniewicz R,Sulkowska U,Baltaziak M,Leśniewicz T,Sulkowski S

    更新日期:2011-07-01 00:00:00

  • [The relationship between the levels of proinflammatory cytokines, and AFI value in pregnancies complicated by premature rupture of membranes].

    abstract:OBJECTIVE:The aim of the study was to test the relationship between maternal serum proinflammatory cytokines level and AFI (amniotic fluid index) in pregnancies complicated by premature rupture of membranes (PROM). MATERIALS AND METHODS:The maternal serum levels of IL-6, IL-1 beta and TNF-alfa were assessed in patient...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Poniedziałek-Czajkowska E,Leszczyńska-Gorzelak B,Oleszczuk J

    更新日期:2001-12-01 00:00:00

  • [Effectiveness of tissue microarray technique for the assessment of estrogen and progesterone receptors expression in endometrioid endometrial cancer--preliminary report].

    abstract:OBJECTIVES:To assess the effectiveness of the donor-block biopsies with a 2 mm-size needle in endometrioid endometrial cancer (EEC) in the tissue microarray (TMA) technique and the application of the TMA for estrogen receptors (ER) and progesterone receptors (PR) expression in EEC. MATERIAL AND METHODS:The study exami...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Gottwald L,Sek P,Kubiak R,Pasz-Walczak G,Piekarski J,Szwalski J,Suzin J,Tyliński W,Hendzel K,Jeziorski A

    更新日期:2012-05-01 00:00:00

  • [Collagen degradation products in amniotic fluid].

    abstract::It was found that amniotic fluid (38-42 Hbd) contains hydroxyproline in concentration about 10 micrograms/ml. Gel filtration and dialysis demonstrated that most of hydroxyproline exists in a form of low molecular weight products. Furthermore, it was found that amniotic fluid contains a protein which eluates during gel...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Gogiel T,Bielecki DA

    更新日期:1996-09-01 00:00:00

  • [Cord blood insulin and erythropoietin levels in relation to the mode of delivery].

    abstract:UNLABELLED:The aim of the study was evaluation, whether cord blood insulin (Ic) and erythropoietin (EPO) levels differ in accordance with mode of delivery: cesarean section (CS) or vaginal delivery (VD). MATERIAL AND METHODS:The study was performed in the diabetic group consisted of 148 newborns of diabetic mothers (N...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Czeszyńska MB,Ronin-Walknowska E

    更新日期:1999-10-01 00:00:00

  • The risk of hyperbilirubinemia in term neonates after placental transfusion - a randomized-blinded controlled trial.

    abstract:OBJECTIVE:We aimed to demonstrate non-inferiority of delayed cord clamping (DCC) and cord milking (CM) in comparison to early cord clamping (ECC) in the incidence of hyperbilirubinemia requiring phototherapy. MATERIAL AND METHODS:467 of maternal-foetal dyads were screened for eligibility. 389 term infants, of breastfe...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.a2020.0096

    authors: Seliga-Siwecka JP,Puskarz-Gasowska J,Tolloczko J

    更新日期:2020-01-01 00:00:00

  • [Vulvovaginitis in girls. I. Characteristics of the investigated population].

    abstract::The group of 277 girls treated for vulvovaginitis was investigated. Any objective and subjective factors, which could effect on occurrence of this disease at girls were analysed. Over 2/3 of investigated girls were before menarche, 36.5% were 3-7 years old. Over 30% had urinary tract infections, 10%--tonsillitis. No e...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Szczurowicz A,Szczurowicz A,Witek K,Grelewski S,Jarosiński B,Maciejewski K

    更新日期:1993-07-01 00:00:00

  • Comparison of endometrial biopsy and postoperative hysterectomy specimen findings in patients with atypical endometrial hyperplasia and endometrial cancer.

    abstract:OBJECTIVES:The aim of the study was to assess the concordance between the preoperative endometrial sampling and microscopic examination of the hysterectomy specimens in patients surgically treated for atypical endometrial hyperplasia and endometrial carcinoma. MATERIAL AND METHODS:We analysed a group of 204 patients, ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.2016.0031

    authors: Kisielewski F,Gajewska ME,Marczewska MJ,Panek G,Wielgoś M,Kamiński P

    更新日期:2016-01-01 00:00:00

  • [Evaluation of safety and effectiveness of pelvic organ prolapse treatment with the use of polypropylene mesh depending on mesh and application technique].

    abstract:OBJECTIVES:Evaluation of safety and effectiveness of POP (pelvic organ prolapse) treatment with the use of polypropylene mesh depending on type of mesh and application technique. MATERIALS AND METHODS:We carried out a retrospective study and compared the frequency of perioperative complications and treatment results t...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.17772/gp/1610

    authors: Banach R,Antosiak B,Blewniewska G,Malinowski A

    更新日期:2013-07-01 00:00:00

  • [Human papilloma virus infection in pregnant women with normal pap-smears, HPV oncogenity and risk factors].

    abstract:UNLABELLED:The process of carcinogenesis in both types of cervical carcinoma is dependent on the infection of oncogenic types of HPV. HPV infection could be diagnosed on the basis of whether or not the DNA virus in present. In pregnant women the latent-persistent infection easily changes into its active form. This proc...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Nowak Z,Karowicz-Bilińska A

    更新日期:2007-09-01 00:00:00

  • [The possibility of cardiovascular system evaluation in fetuses at 11.0 to 13.6 weeks of gestation in a reference perinatal cardiology centre].

    abstract:OBJECTIVE:To assess the possibility of foetal circulatory system evaluation between 11+0 to 13+6 weeks of gestation in a reference perinatal cardiology centre. MATERIAL AND METHODS:A prospective study was conducted between January 2004 and June 2008 in patients admitted to the reference perinatal cardiology centre for...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Własienko P,Hamela-Olkowska A,Jalinik K,Dangel J

    更新日期:2009-04-01 00:00:00

  • [Amniocentesis and amniotic infusion: benefits and risks].

    abstract::The introduction of the amnioinfusion technic in the treatment of chosen complications of pregnancy, requires an easy access to the amniotic cavity. Catheterisation of the amniotic cavity requires the skilled technic, and is not associated with the rise of the obstetrics complications. ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Heimrath J,Pajak J,Zalewski J,Kłósek A,Florjański J

    更新日期:1998-02-01 00:00:00

  • [The management of subarachnoid hemorrhage in pregnancy].

    abstract::Subarachnoid haemorrhage (SAH) from an intracranial aneurysm or arteriovenous malformation is a grave complication of pregnancy. Authors critically analyzed 12 cases of verified SAH during pregnancy from an 11 identified and 1 unidentified cerebral vascular malformation. Aneurysms were responsible for SAH in 7, and ar...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Zukiel R,Jankowski R,Tokarz F

    更新日期:1992-04-01 00:00:00

  • [Electroresectoscopy in submucous fibroids, intrauterine adhesions and uterine malformation treatment].

    abstract::182 hysteroscopic operations with electroresectoscope use performed in Ist Department of Obstetrics and Gynaecology (Warsaw) between 1996-1999 were analyzed. Myomectomy was performed in 117 patients, resection of uterine septum in 25 and deliberation of intrauterine adhesions in 40 patients. Abnormal bleeding and infe...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Szymański R,Kamiński P,Marianowski L

    更新日期:2000-09-01 00:00:00

  • [Anorexia nervosa in woman with Turner's syndrome].

    abstract::The authors report a case of anorexia nervosa in woman with Turner's syndrome (45, X). In this case there was a low blood concentration of LH and FSH, and there was a lack of reaction to intravenous administration of 100 micrograms of GnRH. Partial syndrome of "empty sella" was found in a presented case by use of magn...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Skałba P,Jez W,Kabzińska M

    更新日期:2002-06-01 00:00:00

  • [Age at menarche and the investigation of selected biophysical parameters in the course of menarche].

    abstract:DESIGN:The aim of our study was a currently clinical analysis of menarche. MATERIALS AND METHODS:The mean age of menarche was investigated in 4497 girls between 1975-1997 69 girls were examined throughly in the course of menarche. Age at menarche, body weight, height, body mass index (BMI), some of the hormones and ul...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Kurdzielewicz M,Rzepka-Górska I,Błogowska A,Kosmowska B

    更新日期:1999-05-01 00:00:00

  • Prediction of short-term newborn infectious morbidity based on maternal characteristics in patients with PPROM and Ureaplasma species infection.

    abstract:OBJECTIVES:Preterm premature rupture of membranes (PPROM) complicates about 5% of pregnancies. Ureaplasma species is the most common pathogen found in the amniotic fluid in pregnancieneonatal outcome. The aim of the following study was to evaluate the impact of colonization with the Ureaplasma spp. on pregnant women wi...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.17772/gp/57857

    authors: Mikołajczyk M,Wirstlein PK,Wróbel M,Mazela J,Chojnacka K,Skrzypezak J

    更新日期:2015-09-01 00:00:00

  • [Statistical methods applied in retrospective risk assessment of endometrial adenocarcinoma occurrence].

    abstract::A retrospective study about frequency of occurrence of endometrial adenocarcinoma in postmenopausal women which are associated with diabetes mellitus, overweight and hypertension was performed. The aim of the study was to have risk factors for carcinoma of endometrium estimated. The nonparametric statistics such as: 2...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Friebe Z,Breborowicz GH,Nowakowski B

    更新日期:1997-08-01 00:00:00

  • [Maternal serum concentration of placental growth factor (PIGF) and endothelial growth factor (VEGF) in pregnancies complicated by preeclampsia].

    abstract:UNLABELLED:Preeclampsia is one of the most frequent and dangerous complications of a pregnancy. In preeclamptic pregnancies the spiral arteries are not modified properly. Disturbed blood flow finally leads to hypoxia which is responsible for the dysfunction of the endothelium. Endothelial growth factor (VEGF) and place...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Semczuk-Sikora A,Krzyzanowski A,Kwiatek M,Semczuk M

    更新日期:2007-11-01 00:00:00

  • [The effectiveness of hysteroscopic intrauterine septum resection in terms of reproductive outcome].

    abstract::Uterine septum is the major intrauterine disorder associated with infertility and recurrent abortions. The aim of the study was to find out what is the effectiveness of hysteroscopic intrauterine septum resection in terms of reproductive outcome and in comparison with conventional procedure. The mean follow up period ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Szamatowicz J,Tomaszewska I,Szamatowicz M

    更新日期:1998-10-01 00:00:00

  • [Correlation between the expression of mRNA of histones H2B and H4 and mRNA of kinin receptors B1 and B2 assessed by QRT-PCR in vulvar cancer].

    abstract:OBJECTIVES:Histones are involved in process of proliferation and differentiation of the cells. In many lesions the expression of mRNA of histones is a marker of proliferation. The expression of kinin receptors B1 and B2 coexist with inflammatory processes, but in some studies the expression of these receptors was found...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Olejek A,Mazurek U,Kuśmierz D,Michalska A,Wilczok T

    更新日期:2002-11-01 00:00:00

  • [Expression of caspase 9 and p53 in uterine leiomyosarcomas].

    abstract:UNLABELLED:Uterine sarcomas are heterogeneous malignancies, both clinically and histologically. The process of oncogenesis depends on gene mutations and uncontrolled mitotic cell division that is promoted by blocking pathways of apoptosis. Caspase 9 and p53 protein play an important role in the process of cell apoptosi...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.17772/gp/1778

    authors: Kułak K,Bobiński M,Polak G,Jedrych BJ,Kotarski J,Bednarek W

    更新日期:2014-08-01 00:00:00

  • Transvaginal salpingo-oophorectomy with gasless laparoscopy - an optional pure natural orifice transluminal endoscopic surgery.

    abstract:OBJECTIVES:To establish the appropriate technique for salpingo-oophorectomy via transvaginal natural orifice transluminal endoscopic surgery (NOTES), under gasless laparoscopy. MATERIAL AND METHODS:Ten patients with clinical indication underwent gasless laparoscopic transvaginal salpingo-oophorectomy with concurrent v...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.2020.0001

    authors: Liu T,Chen Y,Wang X

    更新日期:2020-01-01 00:00:00

  • Leptin regulation of aromatase activity in adipose stromal cells from regularly cycling women.

    abstract:OBJECTIVES AND DESIGN:Leptin, a product of adipocytes, is a cytokine with multiple effects on the reproductive axis. Leptin causes the activation of STAT proteins within target cells. The aromatase gene promoter in adipose stromal cells contains a functional STAT binding region, leading to the hypothesis that leptin ma...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Magoffin DA,Weitsman SR,Aagarwal SK,Jakimiuk AJ

    更新日期:1999-01-01 00:00:00

  • [Antibiotic administration in preterm delivery].

    abstract:DESIGN:Although an association between subclinical intrauterine infection and preterm birth is well established, there is conflicting evidence regarding the benefits of antibiotic administration in women in preterm labor. OBJECTIVES:We attempted to determine the effect of antibioticotherapy in mothers on congenital ne...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Pieta-Dolińska A,Jaczewski B,Wardecka J,Woźniak P,Wilczyński J,Krasomski G,Oszukowski P

    更新日期:2005-06-01 00:00:00

  • [Concentration of fibronectin and its possible role in unexplained infertility in relationship to testosterone, FSH and LH levels].

    abstract::The group of 100 men, divided into two groups according to WHO criteria concerning the spermatozoa content was evaluated. The group of 44 oligospermic and azoospermic men was compared with the control group consisting of 56 normospermic men by means of Mann-Whitney U. The statistically significant differences were est...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Krzemiński A,Sikorski R,Milart P

    更新日期:1998-06-01 00:00:00

  • [Postcoital test evaluated in peritoneal fluid].

    abstract::The role of the peritoneal fluid in the physiology of reproduction, as well as in the transportation and survival of gametes, is little recognized. Taking this into consideration, the authors have examined the occurrence of spermatozoa in the peritoneal fluid, collected from patients during diagnostic laparoscopies, f...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Radwan J,Bielak A,Niwald W,Pawlicki J,Banaszczyk R,Makuła D

    更新日期:1995-04-01 00:00:00

  • Prognostic significance of VEGF and its receptors in endometrioid endometrial cancer.

    abstract:BACKGROUND:Angiogenesis is of crucial importance for endometrial tumor growth and Vascular Endothelial Growth Factor (VEGF) is the key mediator of angiogenesis. OBJECTIVE:The purpose of our study was to assess the prognostic value of VEGF and its receptors in relation to endometrioid endometrial carcinomas. MATERIAL ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Dobrzycka B,Terlikowski SJ,Kwiatkowski M,Garbowicz M,Kinalski M,Chyczewski L

    更新日期:2010-06-01 00:00:00