Abstract：
OBJECTIVES:To assess the effectiveness of the donor-block biopsies with a 2 mm-size needle in endometrioid endometrial cancer (EEC) in the tissue microarray (TMA) technique and the application of the TMA for estrogen receptors (ER) and progesterone receptors (PR) expression in EEC. MATERIAL AND METHODS:The study examined EEC tissues from 60 patients. Tissue cores, 2 mm in size, in duplicate, were taken from the formalin-fixed and paraffin-embedded tissue donor blocks and constructed into the TMA recipient block. The presence of EEC tissue in the TMAs was analyzed, and the ER and PR expressions were examined. RESULTS:EEC tissue in TMAs was confirmed in 56 cases (93.33%). In 49 of them (81.67%), both cores presented with cancer tissues. In 4 cases (6.67%) EEC tissue was absent. All cases with ECC present on the TMA slides were appropriate for the ER and PR analysis. In 29 EEC cases (51.98%) both ER and PR were expressed. In 3 cases (5.36%) only ER was expressed, in 8 cases (14.29%) only PR was expressed, and in 16 cases (28.57%) ER and PR were assessed as negative. CONCLUSIONS:Two 2 mm-sized tissue cores from donor-block biopsies constructed into the TMA recipient block were sufficient to diagnose EEC and enabled the assessment of ER and PR expression in 93.3% of the cases. The use of the described TMA technique makes the immunohistochemical study of EEC easier and more time-efficient.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Gottwald L,Sek P,Kubiak R,Pasz-Walczak G,Piekarski J,Szwalski J,Suzin J,Tyliński W,Hendzel K,Jeziorski Asubject
Has Abstractpub_date
2012-05-01 00:00:00pages
342-6issue
5eissn
0017-0011issn
2543-6767journal_volume
83pub_type
杂志文章abstract：DESIGN:Neonatal hypoxia is often responsible for myocardial ischaemia. To evaluate cardiac involvement in neonates, fetal and neonatal ECG recordings have been performed and parameters indicating heart dysfunction have been analysed. OBJECTIVES:Our interest has been focused on analysis of fetal electrocardiogram recor...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-11-01 00:00:00
abstract：OBJECTIVES:The objective of the study was to investigate the detection rates of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealyticum, Gardnerella vaginalis, Escherichia coli, Streptococcus agalactiae and Enterococcus faecalis, showing no clinical signs of an on...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1588
更新日期：2013-05-01 00:00:00
abstract：OBJECTIVES:We investigated how maternal endothelial function is affected by pregestational (Type 1) diabetes mellitus (PGDM) or gestational diabetes mellitus (GDM) and/or chronic hypertension (chHT) or gestational hypertension (PIH). METHODS:We conducted a prospective, observational study involving 78 participants wit...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/62209
更新日期：2016-01-01 00:00:00
abstract：:Cyclopia is a deformation of the facial skeleton with one eye orbit formed in the place where both eyes should be present. As a result of hypoplasia there is absence (hypothesized loss) of central nervous system structures. Teratogenic factors leading to the occurrence of this anomaly may include irregular cholesterol...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2011-03-01 00:00:00
abstract：:Among 94 women with diagnosed "primary" gestosis during pregnancy, 67 patients demonstrated (3-6 months after delivery) chronic glomerulonephritis (25 women) or chronic pyelonephritis (28 women) or hypertension caused by others than nephrologic reasons. "Primary" gestosis was diagnosed correctly only in 29% cases. The...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
abstract：:Obesity-related metabolic and functional disorders may disturb adaptation process taking place in pregnant women body. Insufficient adaptation may lead to development of several medical complications during pregnancy, labor, delivery, and puerperium. Maternal obesity is associated with increased frequencies of hyperte...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：1999-06-01 00:00:00
abstract：OBJECTIVES:Evaluate the time dependent expression of genes in preterm neonates and verify the influence of ontogenic maturation and the environmental factors on the gene expression after birth. MATERIAL AND METHODS:The study was carried out on 20 full-term newborns and 62 preterm newborns (mean birth weight = 1002 [g]...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2017.0080
更新日期：2017-01-01 00:00:00
abstract：:Four cases of young women with Wilson's disease who underwent liver transplantation are presented. The menstrual disturbances associated with Wilson's disease are presented and discussed. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：:The authors presented the frequency of urinary tract infection (u.t.i) in pregnancy in own practice. Additional complications in pregnancy with asymptomatic bacteriuria and acute pyelonephritis were described. Postnatal period of neonates born from mothers with u.t.i. in pregnancy were analyzed. The authors defined th...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：:The terminology quoted in the leaflet "Ultrasonometry of foetus in evaluation of gestational age" could change the diagnostic and therapeutic procedures in obstetrics from the point of view of only one out of many methods of imaging. The object of the study was to complement the "standards for eleven measurements pert...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-02-01 00:00:00
abstract：:Two groups of rats (a control group and the group examined) were administered intraperitoneally supraphysiological doses of hCG in order to induce a "down regulation" effect on the level of receptors LH and to achieve the desensibilization of Leydig cells. The authors tried to find out at which stage of sequence of ch...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1989-05-01 00:00:00
abstract：:350 patients with ovarian cancer were operated and irradiated postoperatively in the Center of Oncology in Kraków. 5-year survival with no recurrence was 41.7% (I.--77.3%, II.--44.1%, III.--7.7%). Stage, histological grade and residual volume tumor appears to be an important prognostic factors. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Bacterial infection is a major cause of neonatal morbidity and mortality. The increased susceptibility of the neonate especially premature one, for bacterial infection is the result of several factors including a delayed maturation of immune response of neonatal B and T cells and deficiencies of the myelopoetic system...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2005-01-01 00:00:00
abstract：:Criminal Law Codification Commission, acting at the Ministry of Justice prepared proposals for amendments in the Polish Penal Code, related to offenses against life and health that were presented to the public in 2013. The draft provides for the protection of the child in the prenatal stage, introducing a new category...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/59562
更新日期：2015-10-01 00:00:00
abstract：UNLABELLED:The aim of the study was to evaluate antioxidant system activity and lipid peroxidations products as markers of oxidative stress in the cord blood of newborns delivered to mothers with diabetes type G1 in comparison to healthy pregnant women. MATERIALS AND METHODS:We examined 10 healthy and 10 diabetic moth...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：:The author describes the experiences and observations of 80 women with the Spider Cu, a Polish IUD. The Spider Cu is a copperbearing spatial IUD which demonstrates high elasticity, resilience, as well as a low pregnancy rate. (author's modified) ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1983-10-01 00:00:00
abstract：:Transvaginal ultrasound scanning was performed on 59 years old women with postmenopausal bleeding in anamnesis. Endometrial thickness was measured at its maximum in both longitudinal and transverse sections of the uterus. Also the thickness of uterus walls and ovaries in 3 planes were measured. Endometrium was irregul...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:A case of a 30 years old pregnant woman suffering from bilateral ovary tumour was presented. When she was sixteen weeks pregnant she had both tumours enucleated using the method of laparoscopy. Diagnostic and therapeutic process have been described. Authors are convinced that laparoscopy as a method of treatment can b...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVES:The purpose of the study was to check the conformity of diagnosis based on macroscopic hysteroscopy image with the respective pathology report. MATERIALS AND METHODS:Study population consisted of 160 patients aged 45-86 years, with abnormal uterine bleeding or abnormal ultrasonographic image of endometrium....
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：:Oral anticoagulants are contraindicated during pregnancy, especially during the I and III trimester, therefore heparin is recommended instead. We used fraxiparine s.c. once daily in prophylactic doses in 6 patients during pregnancy and labor (mean time of prophylaxis 6.5 months). Two of them received fraxiparine becau...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1996-11-01 00:00:00
abstract：OBJECTIVES AND DESIGN:The aim of this study was retrospective analysis of ultrasound and echocardiographic examinations in fetuses with diagnosis of posterior urethral valve, at the referral center from the database of our unit in 8 years (1994-2002). RESULTS AND CONCLUSIONS:Among 8525 ultrasound and echocardiography ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
abstract：:Emergency cerclage was performed on 27 years old patient with membrane prolapse in 21 weeks' gestation. Ultrasonographically guided amniocentesis was performed intraoperatively in order to decrease intraamniotic pressure. Aggressive prophylactic management (wide spectrum antibiotics and tocolysis-nifedipine) resulted ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVES:Newborns hyperbilirubinemia is an interesting, complicated and controversial clinical problem. An elevated concentration of it can be connected with increased risk of jaundice. Also, maternal bilirubin can play a part in the development of jaundice in mature newborns. MATERIAL AND METHODS:The research inclu...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-08-01 00:00:00
abstract：OBJECTIVES:The aim of this study is to assess the choroidal thickness (CT) with use of EDI-OCT in patients before and after delivery depending on the mode of delivery. MATERIAL AND METHODS:The study involved 146 eyes of 73 patients aged 20-34 years, after natural labour (66 eyes) and C-section (80 eyes). Main inclusio...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2020.0137
更新日期：2020-01-01 00:00:00
abstract：:Fetal face is the key anatomical location, both psychologically and clinically for the mother and the clinician. Ultrasound prenatal examination of the maxillofacial region allows to evaluate the fetal face in the first weeks of gestation. In ambulatory intravaginal ultrasound, sensitivity of the facial defect detecti...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.17772/gp/1643
更新日期：2013-09-01 00:00:00
abstract：:Renal cell carcinoma accounts for 75% of renal neoplasms. Clear cell carcinoma is diagnosed in about 80% of the cases. Renal cell carcinoma most frequently metastasizes to the lungs (50-60%), lymph nodes (36%), bones (30-40%), liver (30-40%), and brain (5%). In other organs the metastasis changes are observed very rar...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1620
更新日期：2013-07-01 00:00:00
abstract：OBJECTIVES:To evaluate the balloon occlusion of the internal iliac arteries during a caesarean section in the group of patients with placenta accreta spectrum. MATERIAL AND METHODS:We analysed 29 pregnant women with placenta accreta spectrum. The study group consisted of 15 patients, who underwent a caesarean delivery...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2020.0180
更新日期：2021-01-15 00:00:00
abstract：:Concentrations of iron, zinc and copper were determined in public hair of women with threatened abortion and in full-term pregnancy. The aim of the studies was to find differences between the levels of studied elements in public hair of women with threatened abortion and in full-term pregnancy and to test whether pari...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-07-01 00:00:00
abstract：OBJECTIVES:G-CSF is a stimulatory factor of granulocyte colony formation. In vitro and in vivo G-CSF stimulates the proliferation of granulocyte precursors and enhances phagocytic functions of mature cells. Indirect evidence of this might be the increase of the activity of granulocyte enzymes participating in phagocyto...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-02-01 00:00:00
abstract：:120 adolescent girl suffered from acyclic pelvic pain and dysmenorrhoe (algomenorrhoee) was presented. They were treated with nonsteroidal anti-inflammatory drugs (NSAIDs) and oral contraceptive pills (OCPs) and underwent a laparoscopy to determine the etiology of pelvic pain. Endometriosis was classified according to...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
