Abstract：
OBJECTIVES:The role of angiogenesis in leiomyosarcomas still remains unclear. The aim of this study was to evaluate the NRP1 expression in the leiomyosarcoma tissues and to find the relations between its expression and the clinical features. MATERIAL AND METHODS:The study group consisted of 50 patients with diagnosis of the uterine leiomyosarcoma. Clinical and follow up data were collected. Using immunohistochemical methods the expression of NRP1 was detected. RESULTS:The lack of NRP1 expression was found in 14 cases, positive (weak or moderate) expression was noted in 36 cases. The significantly higher expression of NRP1 was observed in more severe clinical stages in comparison to lower stages of the disease. The significantly shorter survival of patients with the positive expression of NRP1 in leiomyosarcoma was observed. CONCLUSIONS:The expression of NRP1 is associated with clinical advancement and worse prognosis in uterine LMS. Neuropilin 1 can be widely used as a postoperative survival predictor for the patients suffering from uterine LMS.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Bobiński M,Okła K,Kotarski J,Szumiło J,Polak G,Sobstyl M,Bednarek Wdoi
10.5603/GP.a2018.0002subject
Has Abstractpub_date
2018-01-01 00:00:00pages
7-12issue
1eissn
0017-0011issn
2543-6767pii
VM/OJS/J/56167journal_volume
89pub_type
杂志文章abstract：:Angiogenesis or the formation of new vessels out of pre-existing capillaries is a sequence of events that is fundamental to physiology of the female reproductive tract and also pathologic processes such as ovarian hyperstimulation syndrome. Many factors include vascular endothelial growth factor (VEGF), angiopoietins ...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2004-08-01 00:00:00
abstract：:Worldwide screening for early detection of ovarian cancer in both, the general population and the group of women at high risk for ovarian cancer including BRCA genes mutations carriers, has proven to be ineffective. The recommended screening methods, including a pelvic examination, transvaginal ultrasound, and CA125 p...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.17772/gp/1735
更新日期：2014-05-01 00:00:00
abstract：:The role of the peritoneal fluid in the physiology of reproduction, as well as in the transportation and survival of gametes, is little recognized. Taking this into consideration, the authors have examined the occurrence of spermatozoa in the peritoneal fluid, collected from patients during diagnostic laparoscopies, f...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：OBJECTIVES:To analyze the correlation between ultrasound typing and treatment modality of patients with an intrauterine ectopic pregnancy (cervical and cesarean scar). MATERIAL AND METHODS:We retrospectively enrolled 65 patients diagnosed with cesarean scar pregnancy (CSP) or cervical pregnancy (CP) between February 2...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2020.0026
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:Predictive factors of damage to the Fallopian tube may guide the treatment for patients with tubal pregnancy. The purpose of this study was to evaluate the predictive value of ultrasonographic findings in patients affected by ampullary pregnancy for the determination of the depth of trophoblastic infiltration...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1893
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to assess the usefulness of various tumor markers (CA125, HE4, bcl2) measured in serum, urine and saliva in the differential diagnosis of adnexal masses. MATERIAL AND METHODS:Our study was conducted at the Başkent University Medical School, Department of Obstetrics and Gynecology, A...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2016.0045
更新日期：2016-01-01 00:00:00
abstract：UNLABELLED:THE OBJECTIVES: The aim of this study was to evaluate the clinical value of blood flow indicies for differentiating between benign and malignant ovarian tumours. MATERIALS AND METHODS:Realisation of the aim was based on the analysis of examinations' results of 686 ovarian tumors. For each recorded blood flo...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-08-01 00:00:00
abstract：:A monochorionic monoamniotic (MCMA) twin pregnancy is the rarest form of twin gestation, accounting for around 1:10000 to 1:20000 of all deliveries regardless of the region of the world. All multiple gestations have a higher risk of preterm delivery due to either preterm uterine contractions or asymptomatic cervical s...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2012-12-01 00:00:00
abstract：:Authors presented successful conservative treatment early diagnosed cervical pregnancy. After this procedure abdominal hysterectomy was not necessary. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：OBJECTIVES:Comparison of the ability to inhibit alloactivated lymphocytes proliferation of human Wharton Jelly (WJ) and amniotic membrane (AM) mesenchymal stem cells (MSCs) from preterm and term pregnancies. MATERIAL AND METHODS:Term-WJ-MSCs (n = 5) and Preterm-WJ-MSCs (n = 1) were obtained from tissue explants by adh...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2017.0037
更新日期：2017-01-01 00:00:00
abstract：:The study presents the results of treatment of 63 women with stage IB adenocarcinoma of the cervix. The treatment consist of radical Wertheim-Meigs hysterectomy with adjuvant brachytherapy or external beam irradiation. A statistical analysis with Kaplan-Meier and cox model was conducted to assess the influence of sele...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：:The opinions about the causes of the endometrial carcinoma have changed since 1995, due to molecular biology progress. The findings concerning the recently discovered suppressor PTEN gene localized on the chromosome 10 -10q23.3, the product of which is a specific phosphatase are especially valuable. The loss of the ge...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:To assess the results of clomiphene citrate ovarian stimulation vs laparoscopic electrocoagulation of the ovaries in infertile women with PCOS. DESIGN:47 women with PCOS were included into the study. 25 of them had ovarian stimulation using clomiphene citrate (100 mg for 5 consecutive days, during 6 cycle) a...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVES:In our study, we tried to investigate the determinants of women's choices about contraception with the aim of discovering whether or not there is a difference in their preferences before and after consultation with a gynaecologist. MATERIAL AND METHODS:A total of 1058 women were enrolled. They were given de...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2017.0115
更新日期：2017-01-01 00:00:00
abstract：:Renal cell carcinoma accounts for 75% of renal neoplasms. Clear cell carcinoma is diagnosed in about 80% of the cases. Renal cell carcinoma most frequently metastasizes to the lungs (50-60%), lymph nodes (36%), bones (30-40%), liver (30-40%), and brain (5%). In other organs the metastasis changes are observed very rar...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1620
更新日期：2013-07-01 00:00:00
abstract：AIM OF THE PAPER:Comparison of conventional cytodiagnostics with molecular identification of DNA and mRNA HPV HR, immunocytochemical test for suppressor protein P16 and nuclear Ki 67 to detect cervical pathology screening of the division to LG SIL and HG SIL. MATERIAL:630 Pap smears were taken from women with suspecte...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2012-12-01 00:00:00
abstract：:Bezoars are the most common foreign bodies of gastrointestinal tract. They contain swallowed hair, different fibres, seeds, nut shells, sweets or drugs. Clinical manifestations vary, depending on the location and size of bezoar, from "no symptoms" to "acute abdomen" syndrome. In this case report, the authors describe ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2008-04-01 00:00:00
abstract：:Thrombotic thrombocytopenic purpura (TTP) is characterized by microangiopathic hemolytic anemia and thrombocytopenia, accompanied by microvascular thrombosis that causes variable degrees of tissue ischemia and infarction. About 10-20% of TTP cases are associated with the pregnancy. Preterm delivery and intrauterine fe...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2008-07-01 00:00:00
abstract：AIM:The aim of the following work was to assess three-level selective perinatal care in Polish voivodeships in 2008 on the basis of the following parameters: birth rates as well as perinatal death rates, divided into three classes of neonatal weights, in hospitals on each of the three levels. The goal of selective peri...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2009-09-01 00:00:00
abstract：:The authors describe diagnostic difficulties connected with proper estimation of stromal sarcoma biological activities, which developed in uterus corpus in 18 year old girl previously treated with hormones, because of irregular painful menses. Macroscopic and microscopic investigations of postoperative specimen allowe...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：INTRODUCTION:Ectopic pregnancy may lead to massive haemorrhage, infertility or death. Prompt diagnosis and treatment are crucial to save patients who would otherwise die. Serum amylase and lipase measurements are known biochemical markers of pancreatic inflammation and a recognized finding that may help diagnose acute ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2009-05-01 00:00:00
abstract：:Theoretically, a woman could bear unlimited number of fetuses. Practically, the human being on the top of his phylogenetic spread, has chosen the singleton birth as its dominant. The anatomical constitution of the woman let her feed no more than two children at the same time. This were probably the reasons for conside...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2004-11-01 00:00:00
abstract：:During the past 15 years, the Wroclaw Medical Academy Institute of Obstetrics and Gynecology experimented on the construction of IUDs. The paper discusses the positive and negative points of those devices which were produced as compared with the Gravigard and the Copper T-200. There were 702 women observed for 7 yea...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1981-03-01 00:00:00
abstract：OBJECTIVES:The aim of the following study was to assess antisperm antibodies in sera samples of infertile men and women, as well as from prepubertal boys by means of flow cytometry. MATERIAL AND METHODS:We tested sera samples of infertile and fertile adult populations, prepubertal boys with gonadal disorders and healt...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2010-08-01 00:00:00
abstract：UNLABELLED:The effective functions of human peripheral blood neutrophil are modulated by regulatory molecules depending on receptor agonists and adhesion molecules. OBJECTIVES:Evaluation of percentage of neutrophil adhesion molecules in pregnancy of diabetic mothers as well as their expression on peripheral blood neut...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：OBJECTIVES:The "gold standard" in surgical treatment of stress urinary incontinence (SUI) is sling operation with polypropylene tape appliance under the mid urethra. There are two types of polypropylene tape which are the most popular nowadays. These two tapes are differently knitted so they have different biomechanica...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:HPV virus infections and other promotion factors in the development of carcinogenic process at 101 girls from different social groups were evaluated. Chronic infection of the cervix was found at the group of 56 smoking girls, aged 15-18, having sexual contacts with many partners. 10 of them were infected by HPV virus....
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：OBJECTIVE:Angiopoietin-related growth factor (AGF) is associated with angiogenesis but it can also affect glucose and energy metabolism. The aim of the study was to determine AGF levels in gestational diabetes mellitus (GDM). MATERIALS AND METHODS:The study included 44 patients with GDM (GDM group) and 33 non-diabetic...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2012-10-01 00:00:00
abstract：OBJECTIVES:We investigated how maternal endothelial function is affected by pregestational (Type 1) diabetes mellitus (PGDM) or gestational diabetes mellitus (GDM) and/or chronic hypertension (chHT) or gestational hypertension (PIH). METHODS:We conducted a prospective, observational study involving 78 participants wit...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/62209
更新日期：2016-01-01 00:00:00
abstract：UNLABELLED:The aim of the study was to evaluate antioxidant system activity and lipid peroxidations products as markers of oxidative stress in the cord blood of newborns delivered to mothers with diabetes type G1 in comparison to healthy pregnant women. MATERIALS AND METHODS:We examined 10 healthy and 10 diabetic moth...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
