[Vitamin D receptor polymorphism in the group of postmenopausal women with low bone mineral density].

Abstract:

OBJECTIVES:Osteoporosis is a multifactoral disease with aetiology depending from the hormonal, environmental, and genetic factors. One of the suggested candidate gene involved in the pathogenesis is the polymorphic gene encoding for vitamin D receptor (VDR). VDR polymorphism was connected with bone mineral density (BMD) and correlated with onset of osteoporosis. The goal of our study was to determine the role of BsmI polymorphism of VDR gene in the group of postmenopausal women with low bone mineral density. MATERIALS AND METHODS:We have analysed the group of 34 postmenopausal women. The DNA analysis was performed using PCR/RFLP (polymerase chain reaction/restriction fragment length polymorphism) assays. RESULTS:In our investigation we have observed statistically higher frequency of B allele (48.5% vs. 41.2%), the lower frequency of b allele (51.5% vs. 58.8%) and bb genotype (8.8% vs. 42.5%) in the investigated group of postmenopausal women with low BMD. CONCLUSIONS:Our observations could suggest the important role of B allele of the VDR gene in the pathogenesis of osteoporosis in the group of women with low mineral density and possible protective role of b allele in this disease.

journal_name

Ginekol Pol

journal_title

Ginekologia polska

authors

Seremak-Mrozikiewicz A,Drews K,Dańska A,Spaczyński M,Opala T,Mrozikiewicz PM

keywords:

subject

Has Abstract

pub_date

2004-05-01 00:00:00

pages

367-72

issue

5

eissn

0017-0011

issn

2543-6767

journal_volume

75

pub_type

杂志文章
  • [Bilateral adnexal masses in a pregnant woman--laparoscopic management].

    abstract::A case of a 30 years old pregnant woman suffering from bilateral ovary tumour was presented. When she was sixteen weeks pregnant she had both tumours enucleated using the method of laparoscopy. Diagnostic and therapeutic process have been described. Authors are convinced that laparoscopy as a method of treatment can b...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Maciołek-Blewniewska G,Malinowski A,Cieślak J,Pawłowski T,Woźniak P

    更新日期:2005-05-01 00:00:00

  • [Risk factors for gestational trophoblastic tumors following complete hydatidiform mole].

    abstract:OBJECTIVES:The aim of our study was to determine the factors associated with higher incidence of trophoblastic tumours following complete hydatidiform mole. MATERIAL AND METHODS:Epidemiological and clinical factors were studied in eighty five patients with complete hydatidiform mole evacuated from 1973 to 1997 in Depa...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Grzybowski W,Płoszyński A,Mielnik J,Adamcio-Deptulska M,Preis K,Wojciechowska D

    更新日期:2002-11-01 00:00:00

  • The utility of maternal mean platelet volume levels for early onset neonatal sepsis prediction of term infants.

    abstract:OBJECTIVES:This study is aimed to evaluate the role of maternal mean platelet volume (MPV) levels for antenatal prediction marker of early onset neonatal sepsis in term infants born to mothers who have low infection risk. MATERIAL AND METHODS:A total of 62 pregnant women who gave birth in our hospital and whose neonat...

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    pub_type: 杂志文章

    doi:10.5603/GP.a2017.0058

    authors: Cekmez Y,Dizdar Güleçoğlu M,Özcan C,Karadeniz L,Kıran G

    更新日期:2017-01-01 00:00:00

  • Hormonal contraception in patients with epilepsy.

    abstract:OBJECTIVES:The aim of the study was to evaluate hormonal contraception use in women with epilepsy and to assess the risk of potential interactions between contraceptives and antiepileptic drugs (AEDs). MATERIAL AND METHODS:Data on hormonal contraception were obtained prospectively in women of childbearing age treated ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.2019.0010

    authors: Bosak M,Cyranka K,Slowik A

    更新日期:2019-01-01 00:00:00

  • [Serological estimation of the occurrence of chlamydiosis in children with the upper respiratory tract inflammation and pneumonia in 1993-1996 in the area of Wrocław].

    abstract::The investigation were made of the seasonal occurrence of the upper respiratory tract inflammation and pneumonia probably caused by ch. trachomotis. The immunofluorescence tests of chlamydia trachomatis were done in the blood serum of 1831 children aged from 2 weeks to 6 years hospitalised in Wrocław. The research was...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Sobiech E,Karmowski A

    更新日期:1999-04-01 00:00:00

  • Placenta praevia increta with caesarean section scar invasion.

    abstract:INTRODUCTION:Placenta increta refers to the placenta invading the myometrium. It is a rare but life-threatening condition. The incidence of placenta increta ranges widely from 1 in 540 to 1 in 93,000 deliveries; in Poland it is approximately 0.2% of all deliveries. The occurrence of placenta praevia increta is much low...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Izabela UW,Krzysztof N,Ryszard P,Aneta P

    更新日期:2011-06-01 00:00:00

  • [New molecular methods in prenatal invasive diagnostics].

    abstract::New diagnostic techniques employed in laboratories all over the world enable to create new tests for prenatal genetic diagnosis. They include cytogenetics, molecular-cytogenetics and molecular methods. Chromosomal numerical aberrations (aneuploidies) remain to be the most frequent genetic changes diagnosed prenatally ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Łaczmańska I,Stembalska A

    更新日期:2013-10-01 00:00:00

  • [Clinical significance of echogenic amniotic fluid at term pregnancy].

    abstract:PURPOSE:This study is aimed to determine the clinical significance of echogenic amniotic fluid. MATERIAL AND METHODS:I surveyed 9 at term pregnancies in which the amniotic fluid was echogenic. Morphologic characteristics of amniotic fluid were assessed from samples taken at amniocentesis or upon delivery within one da...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Malinowski W

    更新日期:2002-02-01 00:00:00

  • [Noninvasive prenatal test in the first trimester of pregnancy (NT and estimation of beta-hCG and PAPP-A) in the diagnosis of fetal abnormalities in Polish population--comparison of the biochemistry own normal ranges and literature reported data].

    abstract:THE AIM OF STUDY:Estimation of Polish population standards of the concentrations of pregnancy-associated plasma protein--A (PAPP-A) and free beta--human chorionic gonadotropin (beta-HCG) in the maternal blood between 10.0 and 13.6 week of pregnancy and comparison of the biochemistry own normal ranges and literature rep...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Mandryka-Stankewycz S,Perenc M,Dec G,Sieroszewski P

    更新日期:2009-11-01 00:00:00

  • [Selected legal aspects of the protection of the unborn child in the light of the draft amendment to the Polish Penal Code].

    abstract::Criminal Law Codification Commission, acting at the Ministry of Justice prepared proposals for amendments in the Polish Penal Code, related to offenses against life and health that were presented to the public in 2013. The draft provides for the protection of the child in the prenatal stage, introducing a new category...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.17772/gp/59562

    authors: Urbaniak M,Spaczyński RZ

    更新日期:2015-10-01 00:00:00

  • [Sacrospinous colposacrofixation in the treatment of female pelvic organ prolapse (POP)--analysis of the operation course and complications].

    abstract:OBJECTIVES:Richter operation is used for the enterocele and high rectocoele treatment. There are many modifications of the procedure. Alas, not much data concerning complications and the learning curve of Richter operation is currently at our disposal. DESIGN:The aim of the study is to analyze the course of sacrospino...

    journal_title:Ginekologia polska

    pub_type: 临床试验,杂志文章

    doi:

    authors: Surkont G,Wlaźlak E,Kowalski A,Suzin J

    更新日期:2007-03-01 00:00:00

  • [Growing importance of the Polish Gynaecology--comments of the editorial team].

    abstract::The Impact Factor is a measure of average citation frequency for articles in a specific scientific journal during a specific period of time. IF takes into account the content, sources, layout and frequency and regularity of publishing. In order to get an impact factor, a journal needs to be first put on the Philadelph...

    journal_title:Ginekologia polska

    pub_type: 社论

    doi:

    authors: Spaczyński M,Januszek-Michalecka L,Nowak-Markwitz E,Kedzia W,Spaczyński R,Karowicz-Bilińska A

    更新日期:2010-10-01 00:00:00

  • [The statement of Polish Gynaecologic Society experts concerning drinking water consumption in women in reproductive age, pregnancy and breast feeding].

    abstract::Water is a substance essential for life. It creates the environment of our body, keeps it's homeostasis, enables every biochemical reaction and metabolic processes in human organism. Maternal hydratation is essential for homeostasis of two organisms and drinking water influences the amniotic fluid volume, fetal well-b...

    journal_title:Ginekologia polska

    pub_type: 指南,杂志文章,实务指引

    doi:

    authors: Tomasz N,Polish Gynaecological Society.

    更新日期:2009-07-01 00:00:00

  • Can neonates born at 34 weeks be classified as late preterm?

    abstract:OBJECTIVES:In recent years, much attention has been given to infants born prematurely, at 34 0/7 to 36 6/7 weeks of gestation (WG), which have been classified as 'late preterm'. Neonates from that subgroup are less physiologically and metabolically mature than term infants. The aim of the study was to determine whether...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.2016.0092

    authors: Baumert M,Surmiak P,Walencka Z,Mrowiec E,Sodowska P

    更新日期:2016-01-01 00:00:00

  • [Stage IIb invasive carcinoma of the cervix during pregnancy--personal experience and contemporary opinions on this topic].

    abstract::Five cases of the cervical cancer in stage II b coexisting with pregnancy were presented. All patients were treated by radical radiotherapy consisting of external beam irradiation and brachytherapy. The spontaneous abortion or premature labor occurred during radiation after the dose 30.6-32 Gy of irradiation was deliv...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Bidziński M,Zieliński J,Panek G

    更新日期:2002-01-01 00:00:00

  • [Sexual life after hysterectomy].

    abstract:OBJECTIVES:The evaluation of sexual life after hysterectomy is still controversial. DESIGN:The aim of the study was to analyse the impact of hysterectomy on frequency and quality of the woman's sexual life. MATERIAL AND METHODS:The total of 539 women operated in II Department of Obstetrics and Gynecology in 1990-2000...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Wydra D,Ciach K,Sawicki S,Emerich J

    更新日期:2003-07-01 00:00:00

  • [Chemokines in the diagnosis of neonatal infections].

    abstract::Bacterial infection is a major cause of neonatal morbidity and mortality. The increased susceptibility of the neonate especially premature one, for bacterial infection is the result of several factors including a delayed maturation of immune response of neonatal B and T cells and deficiencies of the myelopoetic system...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Beck B,Królak-Olejnik B

    更新日期:2005-01-01 00:00:00

  • Positive correlation between serum omentin and thrombospondin-1 in gestational diabetes despite lack of correlation with insulin resistance indices.

    abstract:UNLABELLED:Gestational Diabetes (GDM) is characterized by insulin resistance and a pro-inflammatory state, both factors possible related to adipokine expression. SUBJECTS AND METHODS:The study included 20 women with GDM, diagnosed according to the WHO criteria, and 23 matched for age and BMI women with normal glucose ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Lewandowski K,Nadel I,Lewinski A,Bienkiewicz M,Tan B,Randeva HS,Cypryk K

    更新日期:2010-12-01 00:00:00

  • Long-term outcomes of radical and conservative surgery for late diagnosed tubal pregnancies.

    abstract:OBJECTIVE:To investigate long-term postoperative outcomes of conservative and radical surgery in ectopic tubal pregnancies, and evaluate the results of these techniques. METHODS:A total of 145 patients that operated for tubal pregnancy between January 2006 and January 2009 were reviewed. Data on patient age, reproduct...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Ozler A,Turgut A,Evsen MS,Sak ME,Soydinç HE,Başaranoğlu S,Celik Y,Taner MZ

    更新日期:2012-04-01 00:00:00

  • [Hormone replacement therapy and cardio-vascular disease].

    abstract::The results of large randomized trials such as the Women's Health Initiative (WHI), Heart and Estrogen / Progestin Replacement Study (HERS) or Estrogen Replacement and Atherosclerosis Study (ERAS) as well as the Million Women Study (MWS) which does not meet criteria RCT, concerning, among others the impact of HRT on b...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:10.17772/gp/61022

    authors: Lesiak M,Mariola RL,Podkowa N

    更新日期:2016-01-01 00:00:00

  • [A single dose of antibiotic--as a prophylaxis during cesarean section].

    abstract::The are shown the expediency of prophylactic antibiotics administration during cesarean section. The investigations contained 32 pregnant women who were given intravenously augmentin in dose of 1.2 g. The control group was made from 31 pregnant women who do not received antibiotic. In both group cesarean section was p...

    journal_title:Ginekologia polska

    pub_type: 临床试验,杂志文章

    doi:

    authors: Krasnodebski J,Stolecki M

    更新日期:1997-01-01 00:00:00

  • [Gestational trophoblastic disease in a 15-year-old girl].

    abstract::Authors described gestational trophoblastic disease in 15 year old girl with concomitant disseminated intravascular clotting. beta HCG was higher that 100,000 mIU/ml. Serum beta HCG level decreased after evacuation of a molar pregnancy. Physiological level was achieved 3 months later. Theco-lutein cyst grew smaller in...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Tarnowski B,Rzepka-Górska I

    更新日期:1999-05-01 00:00:00

  • The effect of lymph node metastasis on overall survival and disease-free survival in vulvar cancer patients.

    abstract:OBJECTIVES:To examine the effect of lymphadenectomy on survival in patients with squamous cell vulvar carcinoma. MATERIAL AND METHODS:Patients with squamous cell vulvar cancer who underwent surgery were retrospectively analyzed. All procedures were performed according to current recommendations/standard of treatment. ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.2020.0018

    authors: Karataşlı V,Erkılınç S,Çakır İ,Can B,Karadeniz T,Gökçü M,Sancı M

    更新日期:2020-01-01 00:00:00

  • [Seventh caesarean section with the same woman--case report].

    abstract::Seventh caesarean section in the same pregnant woman was described. Pregnancy was terminated in 36 week of gestation cause of preterm uterine activity, after getting pulmonary maturation and estimating ultrasound fetal weight over three kilograms. The caesarean section and postoperative period were uncomplicated. Ther...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Jakiel G,Robak-Chołubek D,Przytuła-Piłat M,Semczuk-Sikora A

    更新日期:2001-12-01 00:00:00

  • Evaluation of asthma course in pregnancy.

    abstract::The prevalence of asthma has been rising in recent decades. It is the most common disease among pregnant women andaffects ca. 12% of this population. The course of asthma in pregnancy may change. In 1/3 of patients, it worsens; in 1/3 ofpatients, the symptoms are milder; in 1/3 of patients, it remains unchanged. Well-...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:10.5603/GP.2019.0080

    authors: Rey A,Jassem E,Chelminska M

    更新日期:2019-01-01 00:00:00

  • [Treatment of cervical pregnancy with systemic methotrexate and KCI solution injection into the gestational sac--case report and review of literature].

    abstract::We report a case of a 6-week cervical pregnancy successfully treated with systemic methotrexate and gestational sac biopsy with 15%-calcium chloride solution injection. Serial monitoring of human chorionic gonadotropin levels, combined with ultrasound examinations, confirmed spontaneous miscarriage. Applied treatment ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Polak G,Stachowicz N,Morawska D,Kotarski J

    更新日期:2011-05-01 00:00:00

  • [Serum CA125 variability--new aspects of clinical usefulness].

    abstract::Serum levels of CA125 turned out to be a valuable parameter not only as a marker of ovarian carcinoma but also in other fields of obstetrics and gynaecology. Up to date most of the studies dealing with the subject remain experimental and their clinical usefulness is not widely acknowledged. Accessible and relatively c...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Fiegler P,Kamiński K,Wegrzyn P

    更新日期:2003-05-01 00:00:00

  • [Anterior approach sacrospinous colpopexy in a patient with vaginal vault prolapse, stress urinary incontinence and cystocoele with lateral defect].

    abstract::We present a case of vaginal vault prolapse after hysterectomy associated with cystocoele with central and lateral defect and stress urinary incontinence, that was treated surgically with employment of sacrospinous colpopexy through anterior approach (from paravesical space), combined with anterior colporrhaphy by dou...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Malinowski A,Bobin L,Maciołek-Blewniewska G

    更新日期:2006-03-01 00:00:00

  • Malignant melanoma of the vulva: 2 case reports.

    abstract::It was described two cases of vulvar melanoma malignum. Both women after primary radical treatment, unfortunately died. It was discussed the classification of melanoma malignum, the efficiency of treatment nowadays and the problems in diagnosis. General results of treatment are poor. It is due to tendency for spreadin...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Michalska M,Sajdak S,Obrebowska A,Spaczyński M

    更新日期:1998-05-01 00:00:00

  • [Clinical analysis of patients operated with squamous cell carcinoma of the uterine cervix].

    abstract:OBJECTIVES:The aim of our study was clinical analysis of patients operated with squamous cell carcinoma of the uterine cervix. MATERIALS AND METHODS:Between 1972 and 1991 at the 2nd Department of Obstetrics and Gynecology Medical University of Gdańsk 687 total hysterectomies in Wertheim-Meigs method were performed in ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Sobol A,Emerich J,Kobierski J,Lapińska S,Starnawski M,Stankowska B

    更新日期:1999-02-01 00:00:00