Abstract：
:Gene therapy is an innovative way of treating genetic disorders, which enables removal or repair of genetic defects. Strategies of gene therapy offer new perspectives in treating cancer diseases. Numerous methods for specifically removing tumor cells are currently used. They can be divided into five main strategies: compensation of mutation effect using repression of mutated gene expression, antiangiogenic therapy and suicidal genes to eliminate tumor cells or genetic immunotherapy In the following work actual research status on gene therapy of gynecologic malignances has been presented.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Gromadzka A,Kubiczak M,Jankowska Asubject
Has Abstractpub_date
2010-01-01 00:00:00pages
50-4issue
1eissn
0017-0011issn
2543-6767journal_volume
81pub_type
杂志文章,评审abstract：:Gestational diabetes mellitus (GDM) is a common complication of pregnancy In the course of pregnancy elevated levels of hormones and other proteins having insulin-antagonistic effects lead to higher insulin resistance in peripheral tissues, followed by hyperinsulinemia. Risk factors for the development of GDM have bee...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.17772/gp/2429
更新日期：2015-05-01 00:00:00
abstract：:Irradiation of cancer diseases with intracavitary applicator makes impossible visual control of applicator's position during the process of irradiation. In this paper example applicator moves during the treatment are presented and their influence to dose distribution especially in reference points is discussed. Verifi...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：OBJECTIVES:Preterm premature rupture of membranes (PPROM) complicates about 5% of pregnancies. Ureaplasma species is the most common pathogen found in the amniotic fluid in pregnancieneonatal outcome. The aim of the following study was to evaluate the impact of colonization with the Ureaplasma spp. on pregnant women wi...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/57857
更新日期：2015-09-01 00:00:00
abstract：INTRODUCTION:Malignant neoplasm of the endometrium is the most common malignant neoplasm of the female reproductive system. Toll Like Receptors (TLR) play a significant role in innate and late-immunity against infections or damaged tissues. TLRs are also involved in the development of tumors in their natural microenvir...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2020.0073
更新日期：2020-01-01 00:00:00
abstract：:The World Health Organization announced on 12 March 2020 a global pandemic of the new SARS-CoV-2 coronavirus causing COVID-19 disease associated with pneumonia and acute respiratory failure. SARS-CoV-2 has caused so far over 6.66 million recorded cases, of which 393,000 ended in death (as of June 1, 2020). Despite the...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.5603/GP.a2020.0127
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVES:Overexpression of intracellular adhesion molecule-I (ICAM-1) was observed in many benign and malignant tumors. The aim of our study was to evaluate its serum concentrations as well as CA-125 in women with benign ovarian tumors. MATERIALS AND METHODS:Forty-five women treated surgically because of benign ovar...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-10-01 00:00:00
abstract：:Paper concerns 293 laparoscopic operations. The most frequent types of laparoscopic operations in presented material were: adhesion lysis in minor pelvis (33.8% cases), cystectomy and cyst-ovariectomy (27.6%) and electrocoagulation of ovarian capsule. Operative laparoscopy because of small injury is useful method in t...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：:26 patients out of 48 (54%) with an advanced ovarian carcinoma (III and IV degree) treated in the first stage by means of Adriablastine, Cisplatin and Cyclophosphamide responded to the therapy. Complete remission was achieved in 24 patients (50%), and partial remission (PR) only in 2 patients. Four patients with CR in...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：1989-02-01 00:00:00
abstract：:The main tests of this writing was defining pregnant vagina ecosystem at hospitalized Clinic patients between 5th and 37th pregnant week. Patients was divided on two group: I-st with miscarriage danger, II-nd with premature delivery danger. Bacterial Vaginosis was recognized based into consideration Amsela criterion a...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：:The introduction of the amnioinfusion technic in the treatment of chosen complications of pregnancy, requires an easy access to the amniotic cavity. Catheterisation of the amniotic cavity requires the skilled technic, and is not associated with the rise of the obstetrics complications. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-02-01 00:00:00
abstract：:In this paper the fibronectin gene expression level (Northern blotting) in 33 endometrial samples (residua post abortum, endometrium proliferativum, secretivum and involutivum, hyperplasia glandularis endometrii, adenocarcinoma endometrii) was measured and compared. Higher level of fibronectin gene expression level in...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1995-08-01 00:00:00
abstract：:Adrenocortical carcinoma is a rare tumour with high malignancy and poor prognosis. This tumour is rarely diagnosed in the reproductive age. Complete surgical resection is the only curative treatment for adrenal cancer in all stages. After surgery adjuvant chemotherapy is required. Mitotane is the most important drug i...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2017.0104
更新日期：2017-01-01 00:00:00
abstract：:The stromal Leydig cell tumour (SLCT), a very rare, benign neoplasm was described in 75-year old woman. The patient presented the typical signs of virilisation (hirsutism, masculine alopecia, moderate clitoris enlargement, deep voice) as well as hypertension and insulin independent type of diabetes mellitus (IIDM). Ad...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-10-01 00:00:00
abstract：:The ovarian hyperstimulation syndrome (OHSS) is still a difficult diagnostic and therapeutic problem. OHSS is associated with significant hypertrophy of the ovaries associated with the loss of the intravascular fluid to the third space which results in hypovolaemia, oliguria, electrolyte imbalance, and a rise in haema...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2006-11-01 00:00:00
abstract：:The isolation of cortisol and progesterone binding globulin (CBG) from pregnant women serum was performed using affinity and hydrophobic chromatography. The purity and specificity of isolated transcortin was tested by agarose gel electrophoresis using racket and cross immunoelectrophoresis and specific CBG antibodies....
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：:The course of actinomycetic infections in two females with IUD is presented. Both patients needed surgery. Literature review taking into a special consideration laboratory diagnosis has been performed. Infection caused by other than Actinomyces israelii species was observed. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-07-01 00:00:00
abstract：:During 1986-87, cervical smears were taken at various phases of menstrual cycles from 63 women aged 25-53 (average age of 34.8 years) wearing IUDs for 3 months to 17 years for the sake of cytological evaluation. 43 patients had Copper T-devices of Finnish make, 8 women had Spider Ws of Polish make, 1 had a Lippes Loo...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1988-12-01 00:00:00
abstract：:The current knowledge concerning the fibrocystic disease of the breast is presented in this work. The authors outlined the theoretical principles of the problem and the most important diagnostic methods as well as the prophylaxis and prognostic in the fibrocystic disease of the breast. ...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：1993-01-01 00:00:00
abstract：:EPH-gestosis is accompanied by an extensive remodeling of the extracellular matrix of Wharton's jelly. The gelatinolytic and proteolytic activities were measured. A decrease in gelatinolityc activity and an increase in proteolytic activity in EPH-gestosis were observed. The decrease in gelatinase activity in EPH-gesto...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2002-05-01 00:00:00
abstract：:Some given sex hormones in patients treated due to marital infertility in this paper is analysed. Testosterone, prolactin, FSH and LH were examined. Males with sperm pattern showing evident pathology into our study were chosen: azoospermia, severe oligospermia, kryptozoospermia. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-06-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to assess the level of knowledge of problems referring to breastfeeding among women in childbirth. MATERIALS AND METHODS:The study was based on a questionnaire, which consisted of 20 questions with multiple choice answers. 108 women in puerperium were surveyed-54 in the Obstetrical...
journal_title：Ginekologia polska
pub_type： 杂志文章,多中心研究
doi：
更新日期：2004-01-01 00:00:00
abstract：:This paper sums up the results of treatment with laparoscopy the patients suffering from infertility of unknown reason. Laparoscopy was performed in 75 patients and only in 21.3% of cases the reason of infertility remained unclear. In most of infertile women (90%) different factors of infertility were revealed--among ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：:It was described two cases of vulvar melanoma malignum. Both women after primary radical treatment, unfortunately died. It was discussed the classification of melanoma malignum, the efficiency of treatment nowadays and the problems in diagnosis. General results of treatment are poor. It is due to tendency for spreadin...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：:We were looking for presence, severity and extension of the invasion of vessels, with regard to the prognosis in 275 patient with infiltration limited only to uterine cervix (Ib), in which Wertheim-Meigs surgery was performed. It was found invasion of many vessels- in outside of the cervix is associated with poor prog...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1997-11-01 00:00:00
abstract：UNLABELLED:Cervical incompetence is one of the causes of preterm delivery. Ultrasound examination of the cervix has given the evidence that cervical shortening, dilatation of internal cervical os and funneling observed long before term are the warning signs of preterm delivery. Early diagnosis and treatment may serve b...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVES:The aim of the study is to present data concerning Neugebauer-Le Fort operations performed at the Gynecologic Oncology Clinic, Polish Mother's Health Center Research Institute in Lodz between 2000-2009, including the effects of the surgeries on improving quality of life. MATERIAL AND METHODS:Our research in...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/2063
更新日期：2015-03-01 00:00:00
abstract：:Preterm labor remains to be one of the most important challenges of contemporary perinatology and constitutes the main reason of perinatal mortality and prematurity of neonates. Studies on preterm labor have confirmed the mutual interactions of several different hormonal systems while the activation of hypothalamic- p...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2014-02-01 00:00:00
abstract：:Scientific journals are ranked and evaluated to measure their relative importance and influence on science within a specific field. One of the tools most widely used to evaluate and compare journals is the Thomson Reuters Impact Factor In Poland a specific value of a scientist's Impact Factor is required for academic ...
journal_title：Ginekologia polska
pub_type： 社论
doi：
更新日期：2011-08-01 00:00:00
abstract：:We report a case of a 6-week cervical pregnancy successfully treated with systemic methotrexate and gestational sac biopsy with 15%-calcium chloride solution injection. Serial monitoring of human chorionic gonadotropin levels, combined with ultrasound examinations, confirmed spontaneous miscarriage. Applied treatment ...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2011-05-01 00:00:00
abstract：:Concentrations of Vitamin-C in the urine were determined in 35 women, 25 with normal ovulation and 10 with anovulatory cycles, in an attempt to evaluate the day of ovulation. The concentration was determined daily for 8 days after the oral administration of 500 mg of ascorbic acid. Results were confirmed by comparin...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1977-08-01 00:00:00
