Propylene glycol and contact-lens solutions containing this diol induce pseudocyst formation in acanthamoebae.

Abstract:

:Propylene glycol used as an ophthalmic demulcent in certain contact-lens care systems has been included recently among factors responsible for increasing Acanthamoeba keratitis. In this study, we provide evidence that propylene glycol as well as examined contact-lens solutions containing it induce rapid differentiation of acanthamoebae into pseudocysts. The partial resistance of the pseudocysts and their reversibility to viable trophozoites even after 24-h exposure to the contact-lens solutions indicate a potential risk of infection to contact-lens users.

journal_name

Exp Parasitol

authors

Kliescikova J,Kulda J,Nohynkova E

doi

10.1016/j.exppara.2010.08.014

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

326-8

issue

1

eissn

0014-4894

issn

1090-2449

pii

S0014-4894(10)00279-1

journal_volume

127

pub_type

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