Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis.

abstract：:Infection of human monocyte-derived macrophages (HMDM) and J774 cells (murine macrophage cell line) with several enteroaggregative and cytodetaching Escherichia coli (EAggEC and CDEC, respectively) strains demonstrated that some strains could induce macrophage cell death accompanied by release of lactate dehydrogenase...

journal_title：Infection and immunity

authors： Fernandez-Prada C,Tall BD,Elliott SE,Hoover DL,Nataro JP,Venkatesan MM

更新日期：1998-08-01 00:00:00

abstract：:Saccharomyces boulardii is a nonpathogenic yeast that protects against antibiotic-associated diarrhea and recurrent Clostridium difficile colitis. The administration of C. difficile toxoid A by gavage to S. boulardii-fed BALB/c mice caused a 1.8-fold increase in total small intestinal immunoglobulin A levels (P = 0.00...

journal_title：Infection and immunity

authors： Qamar A,Aboudola S,Warny M,Michetti P,Pothoulakis C,LaMont JT,Kelly CP

更新日期：2001-04-01 00:00:00

abstract：:Ocular toxoplasmosis is a potentially blinding intraocular inflammation. The intent of this study was to investigate the role of Fas-FasL interaction in a murine model of acquired ocular toxoplasmosis induced by intracameral inoculation of Toxoplasma gondii. Intraocular inflammation, Fas and FasL expression on lymphoc...

journal_title：Infection and immunity

authors： Hu MS,Schwartzman JD,Yeaman GR,Collins J,Seguin R,Khan IA,Kasper LH

更新日期：1999-02-01 00:00:00

abstract：:Kinetic, microscopic, and biochemical studies show that virulent Ti (tumor inducing)-plasmid-containing strains of Agrobacterium attach to normal tobacco and carrot tissue culture cells. Kinetic studies showed that virulent strains of A. tumefaciens attach to the plant tissue culture cells in increasing numbers during...

journal_title：Infection and immunity

authors： Matthysse AG,Wyman PM,Holmes KV

更新日期：1978-11-01 00:00:00

abstract：:Attachment of Treponema denticola ATCC 35405 to laminin, a major basement membrane protein, and to other proteins was studied. Microdilution plates were coated with the proteins, and the attachment of T. denticola was measured by the enzyme-linked immunosorbent assay technique. Compared with bovine serum albumin (BSA)...

journal_title：Infection and immunity

authors： Haapasalo M,Singh U,McBride BC,Uitto VJ

更新日期：1991-11-01 00:00:00

abstract：:A group of insertion mutants was used to define the genes of plasmid pDC5 required for the expression of mannose-resistant fimbriae. Minicell experiments identified four polypeptides (71,000, 45,000, 27,000, and 17,000 daltons) concerned with fimbrial production, the smallest of these being the fimbrial subunit. The a...

journal_title：Infection and immunity

authors： Clegg S,Pierce JK

更新日期：1983-12-01 00:00:00

abstract：:In the development of vaccines capable of providing immunity against brucellosis, Cu-Zn superoxide dismutase (SOD) has been demonstrated to be one of the protective immunogens of Brucella abortus. In an earlier study, we provided strong evidence that intramuscular injection with a plasmid DNA carrying the SOD gene (pc...

journal_title：Infection and immunity

authors： Muñoz-Montesino C,Andrews E,Rivers R,González-Smith A,Moraga-Cid G,Folch H,Céspedes S,Oñate AA

更新日期：2004-04-01 00:00:00

abstract：:The concept that relates low virulence of certain alphaviruses to low viremia and efficient vascular clearance of virus was tested in guinea pigs. Previously published studies with hamsters suggested that virulent strains maintain high viremias primarily because they are cleared inefficiently from the blood. In the pr...

journal_title：Infection and immunity

authors： Jahrling PB,Heisey GB,Hesse RA

更新日期：1977-08-01 00:00:00

abstract：:Clostridium perfringens type B causes enteritis and enterotoxemia in domestic animals. By definition, these bacteria must produce alpha toxin (CPA), beta toxin (CPB) and epsilon toxin (ETX) although most type B strains also produce perfringolysin O (PFO) and beta2 toxin (CPB2). A recently identified Agr-like quorum-se...

journal_title：Infection and immunity

authors： Chen J,McClane BA

更新日期：2012-09-01 00:00:00

abstract：:We have recently found that strain B31 infection-immune rabbits are completely protected against homologous challenge with large numbers (>10(6)) of host-adapted Borrelia burgdorferi (HAB) (E. S. Shang, C. I. Champion, X. Wu, J. T. Skare, D. B. Blanco, J. N. Miller, and M. A. Lovett, Infect. Immun. 68:4189-4199, 2000)...

journal_title：Infection and immunity

authors： Shang ES,Wu XY,Lovett MA,Miller JN,Blanco DR

更新日期：2001-01-01 00:00:00

abstract：:Toll-like receptors 2 and 4 (TLR2 and TLR4) have been found to transduce signals of peptidoglycan (PGN) and lipopolysaccharide (LPS), respectively, for NF-kappa B activation. However, little is known about the expression and regulation of the TLR2 gene in monocytes/macrophages in response to the two typical bacterial ...

journal_title：Infection and immunity

authors： Liu Y,Wang Y,Yamakuchi M,Isowaki S,Nagata E,Kanmura Y,Kitajima I,Maruyama I

更新日期：2001-05-01 00:00:00

abstract：:Brucellosis is a bacterial disease of animals and humans. Brucella abortus barely activates the innate immune system at the onset of infection, and this bacterium is resistant to the microbicidal action of complement. Since complement stands as the first line of defense during bacterial invasions, we explored the role...

journal_title：Infection and immunity

authors： González-Espinoza G,Barquero-Calvo E,Lizano-González E,Alfaro-Alarcón A,Arias-Gómez B,Chaves-Olarte E,Lomonte B,Moreno E,Chacón-Díaz C

更新日期：2018-09-21 00:00:00

abstract：:Patients with chronic bronchitis are colonized by and may develop acute bronchopulmonary infection due to nontypable Haemophilus influenzae (NTHI) despite the presence of bactericidal and opsonizing antibody to the infecting organism. To test the hypothesis that secretory immunoglobulin A (IgA) interferes with host de...

journal_title：Infection and immunity

authors： Musher DM,Goree A,Baughn RE,Birdsall HH

更新日期：1984-07-01 00:00:00

abstract：:Analysis of major outer membrane protein (MOMP) profiles of various meningococci by sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis (SDS-PAGE) revealed the presence of 0 to 2 low-molecular-weight, heat-modifiable MOMPs (molecular weight, 25,000 to 32,000) and 1 to 3 high-molecular-weight MOMPs (molecul...

journal_title：Infection and immunity

authors： Poolman JT,de Marie S,Zanen HC

更新日期：1980-12-01 00:00:00

abstract：:Immunization with Plasmodium sporozoites can elicit high levels of sterile immunity, and neutralizing antibodies from protected hosts are known to target the repeat region of the circumsporozoite (CS) protein on the parasite surface. CS-based subunit vaccines have been hampered by suboptimal immunogenicity and the req...

journal_title：Infection and immunity

authors： Carapau D,Mitchell R,Nacer A,Shaw A,Othoro C,Frevert U,Nardin E

更新日期：2013-12-01 00:00:00

abstract：:Monoclonal antibodies against 12 of the 17 IATS serotype strains of Pseudomonas aeruginosa were produced. Eighty-seven hybridoma clones were isolated, and the antibodies secreted were found to be reactive with both Formalin-fixed whole cells and purified lipopolysaccharide of homologous strains in enzyme-linked immuno...

journal_title：Infection and immunity

authors： Lam JS,MacDonald LA,Lam MY,Duchesne LG,Southam GG

更新日期：1987-05-01 00:00:00

abstract：:The genes of the lic1 operon (lic1A to lic1D) are responsible for incorporation of phosphocholine (PCho) into the lipopolysaccharide (LPS) of Haemophilus influenzae. PCho plays a multifaceted role in the commensal and pathogenic lifestyles of a range of mucosal pathogens, including H. influenzae. Structural studies of...

journal_title：Infection and immunity

authors： Fox KL,Li J,Schweda EK,Vitiazeva V,Makepeace K,Jennings MP,Moxon ER,Hood DW

更新日期：2008-02-01 00:00:00

abstract：:A synthetic medium capable of supporting growth of Vibrio parahaemolyticus is described. Growth yields and generation times were comparable to growth in a complex medium, although Kanagawa hemolysin was undetectable in the synthetic medium. Upon the addition of single amino acids to this synthetic medium, only D-trypt...

journal_title：Infection and immunity

authors： Cherwonogrodzky JW,Clark AG

更新日期：1982-07-01 00:00:00

abstract：:The stimulation of mononuclear phagocytes by lipopolysaccharide (LPS) is facilitated by the binding of complexes of LPS and LPS-binding protein to CD14. Although it is clear that CD14 is involved in LPS-induced signaling, other investigators have hypothesized the existence of additional signaling pathways in macrophag...

journal_title：Infection and immunity

authors： Lynn WA,Liu Y,Golenbock DT

更新日期：1993-10-01 00:00:00

abstract：:We investigated a possible cause-and-effect relationship between sensitization against Actinomyces viscosus Nyl and destructive periodontal disease in RIC-Sprague-Dawley rats. Germfree rats (66) were either immunized with A. viscosus Nyl (day 20) or orally infected with A. viscosus Nyl (days 38 and 39) or both. We mea...

journal_title：Infection and immunity

authors： Burckhardt JJ,Gaegauf-Zollinger R,Schmid R,Guggenheim B

更新日期：1981-03-01 00:00:00

abstract：:Alpha-2,3-sialyltransferase (Lst) is expressed on the outer membrane of Neisseria gonorrhoeae and Neisseria meningitidis and sialylates surface lipooligosaccharide (LOS), facilitating resistance to complement-mediated killing. The enzyme is constitutively expressed from a single gene (lst) and does not undergo antigen...

journal_title：Infection and immunity

authors： Packiam M,Shell DM,Liu SV,Liu YB,McGee DJ,Srivastava R,Seal S,Rest RF

更新日期：2006-05-01 00:00:00

abstract：:Cultured mammalian cells extend the time of survival of Treponema pallidum (Nichols strain). Various parameters that have been previously shown to enhance treponemal survival in vitro were examined for influences on the interaction of T. pallidum with cultured cells. With cells derived from normal rabbit testes, the t...

journal_title：Infection and immunity

authors： Fitzgerald TJ,Johnson RC,Sykes JA,Miller JN

更新日期：1977-02-01 00:00:00

abstract：:Infections caused by organisms of the Mycobacterium avium complex occur in approximately 50 to 60% of patients with AIDS. M. avium is an intracellular pathogen that survives and multiplies within mononuclear phagocytes. In this study, we investigated the uptake of M. avium grown within macrophages (intracellular growt...

journal_title：Infection and immunity

authors： Bermudez LE,Parker A,Goodman JR

更新日期：1997-05-01 00:00:00

abstract：:Polyamines such as putrescine, spermidine, and cadaverine are small, polycationic molecules that are required for optimal growth in all cells. The intracellular concentrations of these molecules are maintained by de novo synthesis and transport pathways. The human pathogen Streptococcus pneumoniae possesses a putative...

journal_title：Infection and immunity

authors： Ware D,Jiang Y,Lin W,Swiatlo E

更新日期：2006-01-01 00:00:00

abstract：:Elicited macrophages from 129sv mice with a functional deletion of the natural-resistance-associated macrophage protein 1 gene (Nramp1) were shown to be as susceptible as wild-type mice to infection with the Chlamydia trachomatis mouse pneumonitis and L3 serovars and to Chlamydia pneumoniae. Furthermore, the two group...

journal_title：Infection and immunity

authors： Pal S,Peterson EM,de La Maza LM

更新日期：2000-08-01 00:00:00

abstract：:The cytopathic effect (CPE) of Escherichia coli producing cytotoxic necrotizing factor type 1 (CNF1) was investigated by using a human epithelial cell (HeLa) model of infection with CNF1-producing E. coli BM2-1. This strain was shown to bind loosely, but massively, to HeLa cells. A 4-h interaction between bacteria and...

journal_title：Infection and immunity

authors： De Rycke J,Mazars P,Nougayrede JP,Tasca C,Boury M,Herault F,Valette A,Oswald E

更新日期：1996-05-01 00:00:00

abstract：:Immunity to reinfection in the genital tract of female guinea pigs with the agent of guinea pig inclusion conjunctivitis was found to be dependent upon an intact humoral immune response. Cell-mediated immunity in the absence of humoral immunity had no apparent role in resistance to challenge infection. ...

journal_title：Infection and immunity

authors： Rank RG,Barron AL

更新日期：1983-01-01 00:00:00

abstract：:In an attempt to understand the mechanism of serum resistance in Actinobacillus pleuropneumoniae, in the present study we examined various interactions among the bacterial surface constituents, serum antibodies, and complement. Analysis of swine sera revealed the presence of anticapsular antibodies in convalescent-pha...

journal_title：Infection and immunity

authors： Udeze FA,Kadis S

更新日期：1992-09-01 00:00:00

abstract：:Evidence is presented to indicate that Plasmodium berghei merozoites, but not trophozotites, have an antiphagocytic capsule. The capsule appears to form around the developing merozoties of the schizont in the parasitophorous vacuole. Serum from animals immune to P. berghei reacts with this capsule. After reaction with...

journal_title：Infection and immunity

authors： Brooks C,Kreier JP

更新日期：1978-06-01 00:00:00

abstract：:Monolayer cultures of LLC-MK2 rhesus monkey kidney cells become persistently infected with simian virus 40 after infection at input multiplicities of 100, 10, or 1 plaque-forming unit per cell. After 3 weeks, all cells of the cultures infected at a multiplicity of 1 plaque-forming unit per cell produced the simian vir...

journal_title：Infection and immunity

authors： Norkin LC

更新日期：1977-12-01 00:00:00