Abstract：
:Recent clinical evidence has suggested that tasks performed in kneeling or squatting postures place the knee at a higher risk for injury because loads across the knee might overload the ligaments. The objective of this study was to develop a subject-specific model of the knee that is kinematically driven to predict the forces in the major ligaments at high flexion angles. The geometry of the femur, tibia, and fibula and the load-elongation curves representing the structural properties of the ACL, PCL, LCL, and MCL served as inputs to the model, which represented each ligament as a nonlinear elastic spring. To drive the model, kinematic data was obtained while loads were applied to the same cadaveric knee at four flexion angles. The force in each ligament during the recorded kinematic data allowed an optimization procedure to determine the location of the ligament attachment sites on each bone and their reference lengths. The optimization procedure could successfully minimize the differences between the experimental and predicted forces only when the kinematics at 90°, 120°, and 140° of flexion were utilized. This finding suggests that the ligaments at the knee function differently at high-flexion angles compared to low flexion angles and separate models must be used to examine each range of motion. In the future, the novel experimental and computational methodology will be used to construct additional models and additional knee kinematics will be input to help elucidate mechanisms of injury during tasks performed in kneeling or squatting postures.
journal_name
Med Biol Eng Computjournal_title
Medical & biological engineering & computingauthors
Yang Z,Wickwire AC,Debski REdoi
10.1007/s11517-010-0653-7subject
Has Abstractpub_date
2010-11-01 00:00:00pages
1077-85issue
11eissn
0140-0118issn
1741-0444journal_volume
48pub_type
杂志文章abstract：:Left ventricular volume calibration based on the conductance catheter depends on the correct determination of the parallel conductance (Gp). Baan's saline manoeuvre procedure leads to Gp by finding the end-systolic (Ges) and end-diastolic (Ged) conductances, for each beat of the dilution curve rising limb. After plott...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02513284
更新日期：1999-03-01 00:00:00
abstract：:Fluctuation analysis has great potential to contribute to pulmonary clinical science and practice. We evaluated the relationship between asthma and the respiratory impedance recurrence period density entropy (RPDEnZrs) and the variability (SDZrs). A non-invasive and simple protocol for assessing respiratory mechanics ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-012-0957-x
更新日期：2012-12-01 00:00:00
abstract：:The three-dimensional changes in the cytoskeleton and in cell proliferation of bovine pulmonary artery endothelial cells when exposed to sustained hydrostatic pressure were investigated in vitro using laser scanning confocal microscopy. Subconfluent endothelial cells on rigid substrates were exposed to 1.5, 5 and 10 c...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02523225
更新日期：1998-07-01 00:00:00
abstract：:A new system capable of generating static and dynamic random-element stereograms is designed and implemented. The stereogram is composed of a rectangle that can be varied in size, element density, orientation, and horizontal and vertical disparities, and can be swept at several velocities. The system is based on an in...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02524687
更新日期：1994-07-01 00:00:00
abstract：:This article presents a novel approach of edged and edgeless object-shape recognition and 3D reconstruction from gradient-based analysis of tactile images. We recognize an object's shape by visualizing a surface topology in our mind while grasping the object in our palm and also taking help from our past experience of...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-014-1142-1
更新日期：2014-04-01 00:00:00
abstract：:Global field synchronization (GFS) quantifies the synchronization level of brain oscillations. The GFS method has been introduced to measure functional synchronization of EEG data in the frequency domain. GFS also detects phase interactions between EEG signals acquired from all of the electrodes. If a considerable amo...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-017-1689-8
更新日期：2018-02-01 00:00:00
abstract：:A personal computer system for electrocardiogram (ECG) ST-segment recognition is developed based on neural networks. The system consists of a preprocessor, neural networks and a recogniser. The adaptive resonance theory (ART) is employed to implement the neural networks in the system, which self-organise in response t...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02446186
更新日期：1992-01-01 00:00:00
abstract：:Spinal cord injury patients are under daily risk for developing deep tissue injury which is a severe pressure ulcer that initiates in soft tissues at the bones' proximity. We aimed to formulate a patient-specific biomechanical model that can continuously monitor internal tissue stresses in real time. We adopted a form...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-011-0754-y
更新日期：2011-04-01 00:00:00
abstract：:In this study, we introduce a novel simulation technique to incorporate delineation errors into radiotherapy treatment margins and combine them with organ motion and set-up errors to investigate the cumulative dosimetric effects in different tumour sites. The effects of applying patient realignment correction protocol...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-010-0616-z
更新日期：2010-07-01 00:00:00
abstract：:A generic framework for the automated classification of human movements using an accelerometry monitoring system is introduced. The framework was structured around a binary decision tree in which movements were divided into classes and subclasses at different hierarchical levels. General distinctions between movements...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02347551
更新日期：2004-09-01 00:00:00
abstract：:Gastrointestinal stimulator implants have recently shown positive results in treating obesity. However, the implantation currently requires an invasive surgical procedure. Endoscopy could be used to place the gastric stimulator in the stomach, hence avoiding the riskier surgery. The implant then needs to go through th...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-014-1236-9
更新日期：2015-04-01 00:00:00
abstract：:Electromyography (EMG) in a bio-driven system is used as a control signal, for driving a hand prosthesis or other wearable assistive devices. Processing to get informative drive signals involves three main modules: preprocessing, dimensionality reduction, and classification. This paper proposes a system for classifyin...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-018-1857-5
更新日期：2018-12-01 00:00:00
abstract：:A hypothetical neuromusculoskeletal model is developed to simulate human normal walking and its modulated behaviors. A small set of neural periodic patterns drive spinal muscle synergies which in turn lead to specific pattern of muscle activation and supraspinal feedback systems maintain postural balance during walkin...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-007-0277-8
更新日期：2008-02-01 00:00:00
abstract：:To evaluate the possibility of respiratory-volume measurement using photoplethysmography (PPG), PPG signals from 16 normal volunteers are collected, and the respiratory-induced intensity variations (RIIV) are digitally extracted. The RIIV signals are studied while respiratory volume is varied. Furthermore, respiratory...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02513264
更新日期：1999-01-01 00:00:00
abstract：:To study the effects of the geometrical characteristics of a framing coil on aneurysm thromboembolization efficacy, the hemodynamics in lateral aneurysms filled with coils having a different shape, orientation, and thickness were analyzed using computational fluid dynamics. The aneurysms packed with vortex and cage-sh...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-013-1073-2
更新日期：2013-09-01 00:00:00
abstract：:Architectural distortion is a subtle abnormality in mammograms, and a source of overlooking errors by radiologists. Computer-aided diagnosis (CAD) techniques can improve the performance of radiologists in detecting masses and calcifications; however, most CAD systems have not been designed to detect architectural dist...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-006-0088-3
更新日期：2006-10-01 00:00:00
abstract：:The starting point of this paper is the analysis of the reference problem in intra-cerebral electroencephalographic (iEEG) recordings. It is well accepted that both surface and depth EEG signals are always recorded with respect to some unknown time-varying signal called reference. This article discusses different meth...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-012-0946-0
更新日期：2012-10-01 00:00:00
abstract：:The clinical efficacy of a microwave (MW) hyperthermia system using an electric-field converging (lens) applicator is evaluated for 42 malignant tumours with a maximum tumour depth of less than 7 cm. The mean of the maximum, average and minimum tumour temperature of the 42 tumours are 44.5, 42.5 and 40.7 C, respective...
journal_title：Medical & biological engineering & computing
pub_type： 临床试验,杂志文章
doi：10.1007/BF02522944
更新日期：1995-01-01 00:00:00
abstract：:We present an analytical solution for the electrical potential and activating function (AF) established by cylindrical needle electrodes in anisotropic tissue. We compare this activating function to (1) AF computed assuming line-source electrodes and (2) AF computed using a finite element program. The results show tha...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-009-0508-2
更新日期：2009-09-01 00:00:00
abstract：:Vascular access for renal dialysis is a lifeline for about 120 000 individuals in the United States. Stethoscope auscultation of vascular sounds has some utility in the assessment of access patency, yet can be highly skill-dependent. The objective of the study was to identify acoustic parameters that are related to ch...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02345123
更新日期：2005-01-01 00:00:00
abstract：:Peripheral arterial occlusive disease is a serious cardiovascular disorder. The arterial occlusion leads to turbulent flow and arterial sound generation on the inner vessel wall. Stenosis-induced vibro-acoustic waves propagate through the surrounding soft tissues and reach the skin surface. In this study, the feasibil...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-019-01995-y
更新日期：2019-08-01 00:00:00
abstract：:The tortuosity of retinal blood vessels is an important diagnostic indicator for a number of retinal pathologies. We applied robust quantitative tortuosity metrics, which are well suited to automated detection and measurement, to retinal fluorescein images of normal and diseased vessels exhibiting background diabetic ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-009-0559-4
更新日期：2010-01-01 00:00:00
abstract：:Photoplethysmography imaging (PPGI) for non-contact monitoring of preterm infants in the neonatal intensive care unit (NICU) is a promising technology, as it could reduce medical adhesive-related skin injuries and associated complications. For practical implementations of PPGI, a region of interest has to be detected ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-020-02251-4
更新日期：2020-12-01 00:00:00
abstract：:An efficient and novel modeling approach is proposed in this paper for identifying proteins or genes involved in melanoma skin cancer. Two types of classifiers are modeled, based on the chemical structure and hydropathy property of amino acids. These classifiers are further implemented using NI LabVIEW-based hardware ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-020-02241-6
更新日期：2020-10-01 00:00:00
abstract：:Results of self-consistent analyses of cells show the possibility of temperature increases at membranes in response to a single nanosecond, high-voltage pulse, at least over small sections of the membrane. Molecular Dynamics simulations indicate that such a temperature increase could facilitate poration, which is one ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-011-0745-z
更新日期：2011-06-01 00:00:00
abstract：:A simple inertial measurement unit (IMU) incorporating rate gyroscopes and accelerometers has been tested to investigate the trunk kinematics during the sit-to-stand. It was affixed at trunk L5 level and used for sit-to-stand position and orientation reconstruction. The method was validated with standard optoelectroni...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-007-0224-8
更新日期：2007-10-01 00:00:00
abstract：:An algorithm for determining the frequency and propagation time of the gastric slow wave has been designed for integration into a demand gastric pacing system. The algorithm analyses the serosal activity in both the time and frequency domains, and the results are compared to produce a conclusion only when the values a...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02344688
更新日期：2000-01-01 00:00:00
abstract：:Quantitative analysis and detection of electroencephalogram (EEG) recordings during evoked activities is essential for clinical diagnosis on neurological disorders. However, the process of interpreting EEG is time consuming for electroencephalographers (EEGers). In this study, an automatic EEG interpretation system co...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-010-0688-9
更新日期：2011-02-01 00:00:00
abstract：:An atlas-based multimodal registration method for 2-dimension images with discrepancy structures was proposed in this paper. Atlas was utilized for complementing the discrepancy structure information in multimodal medical images. The scheme includes three steps: floating image to atlas registration, atlas to reference...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-018-1808-1
更新日期：2018-11-01 00:00:00
abstract：:This study is based on the hypothesis that the pressure within the arterial network can be usefully decomposed as the sum of a reservoir pressure and an excess pressure. The reservoir pressure waveform is defined to be the same in each vessel but delayed by the wave travel time from the root of the aorta. Using calcul...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-012-0872-1
更新日期：2012-04-01 00:00:00
