Abstract:
:This study is based on the hypothesis that the pressure within the arterial network can be usefully decomposed as the sum of a reservoir pressure and an excess pressure. The reservoir pressure waveform is defined to be the same in each vessel but delayed by the wave travel time from the root of the aorta. Using calculus of variations and mass conservation, which relates the flow and rates of change of pressure in the vessels, we show that the reservoir pressure waveform minimises the ventricular hydraulic work for any physiologically or clinically reasonable ejection waveform and arterial properties, i.e. vessel compliances and terminal resistances. We conclude that the excess pressure determines the excess work done by the ventricle, which may have clinically important implications.
journal_name
Med Biol Eng Computjournal_title
Medical & biological engineering & computingauthors
Parker KH,Alastruey J,Stan GBdoi
10.1007/s11517-012-0872-1subject
Has Abstractpub_date
2012-04-01 00:00:00pages
419-24issue
4eissn
0140-0118issn
1741-0444journal_volume
50pub_type
杂志文章abstract::To describe upper airway obstruction in patients with sleep apnea syndrome, the steady state solutions of a simple model of local pharyngeal obstruction were studied. Importantly, the present model embodies a series of two individualised elements, each having its own compliance, which enables the consideration, from a...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02510972
更新日期:1997-11-01 00:00:00
abstract::Nowadays, acoustic emission (AE) has its applications in various areas, including mechanical, civil, underwater acoustics, and biomedical engineering. It is a non-destructive evaluation (NDE) and a non-intrusive method to detect active damage mechanisms such as crack growth, delamination, and processes such as frictio...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章,评审
doi:10.1007/s11517-020-02202-z
更新日期:2020-08-01 00:00:00
abstract::Therapeutic hypothermia is a treatment method to reduce brain injuries after stroke, especially for cerebral ischemia. This study investigates in the temperature distribution of the head within selective brain cooling (SBC). Anatomically accurate geometries based on CT images of head and neck regions are used to devel...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-019-01962-7
更新日期:2019-06-01 00:00:00
abstract::In the routine recording of magnetocardiograms (MCGs), it is necessary to underline the problem of noise cancellation. Source separation has often been suggested to solve this problem. In this paper, blind source separation (BSS), by means of singular value decomposition (SVD) and independent component analysis (ICA),...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-006-0055-z
更新日期:2006-06-01 00:00:00
abstract::Magnetoenterography (MENG) is a new, non-invasive technique that measures gastrointestinal magnetic signals near the body surface. This study was undertaken to evaluate the temporal and spatial characteristics of the magnetic signals generated by gastric and duodenal slow wave activity. The gastrointestinal magnetic f...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513347
更新日期:1999-09-01 00:00:00
abstract::The problem of excess cerebrospinal fluid in the brain (hydrocephalus) is generally managed using a passive pressure or flow regulated mechanical shunt. Despite the success of such devices, they have been plagued with a number of problems. It is desirable to have a shunt valve that responds dynamically to the changing...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-010-0716-9
更新日期:2011-01-01 00:00:00
abstract::The Chinese herb radix Salviae miltiorrhizae (RSM) is used in traditional Chinese medicine as a treatment for cardiovascular and cerebrovascular diseases. Several components of the plant extract from salvia mitorrhiza bunge have been determined previously, one of which is protocatechuic acid (PAC). It has been found, ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345308
更新日期:2002-11-01 00:00:00
abstract::A comparison of auditory and visual perception of scatterplots showed similar correlation estimation performance in both modalities. The present study replicated this experiment using electrotactile (electrocutaneous) presentation of scatterplots on the fingertips and abdomen, as well as visual presentation. The corre...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345967
更新日期:2005-03-01 00:00:00
abstract::The mechanical impedance of the ankle joint during electrical stimulation of the soleus is studied by applying constant-velocity 10 degrees angular perturbations to the ankle and measuring the resultant torque. Both neurologically intact subjects and spinal cord injured subjects are tested. Lumped, piecewise linear mo...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02512522
更新日期:1994-05-01 00:00:00
abstract::Divided attention is defined as focusing on different tasks at once, and this is described as one of the biggest problems of today's society. Default examinations for understanding attention are questionnaires or physiological signals, like evoked potentials and electroencephalography. Physiological records were obtai...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-019-02013-x
更新日期:2019-09-01 00:00:00
abstract::Time-varying filtering techniques are applied to the problem of baseline correction by letting the cut-off frequency of a linear filter be controlled by the low-frequency properties of the ECG signal. The time-varying filter is implemented as a bank of linear low-pass filters, in which each filter has a slightly diffe...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02441986
更新日期:1993-09-01 00:00:00
abstract::The paper describes a method of quantifying Duchenne muscular dystrophy which is examiner independent and uses surface electromyographic signals (EMG). A standardised protocol is proposed. Spectral parameters are first computed from digitised EMG, then a polynomial model is deduced from the evolution of each parameter...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02446966
更新日期:1992-05-01 00:00:00
abstract::The three-dimensional changes in the cytoskeleton and in cell proliferation of bovine pulmonary artery endothelial cells when exposed to sustained hydrostatic pressure were investigated in vitro using laser scanning confocal microscopy. Subconfluent endothelial cells on rigid substrates were exposed to 1.5, 5 and 10 c...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02523225
更新日期:1998-07-01 00:00:00
abstract::Fluctuation analysis has great potential to contribute to pulmonary clinical science and practice. We evaluated the relationship between asthma and the respiratory impedance recurrence period density entropy (RPDEnZrs) and the variability (SDZrs). A non-invasive and simple protocol for assessing respiratory mechanics ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-012-0957-x
更新日期:2012-12-01 00:00:00
abstract::Soleus muscle flap as coverage tissue is a possible surgical solution adopted to cover the wounds due to open fractures. Despite this procedure presents many clinical advantages, relatively poor information is available about the loss of functionality of triceps surae of the treated leg. In this study, a group of pati...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-020-02286-7
更新日期:2021-01-01 00:00:00
abstract::In a computer-aided diagnosis (CAD) system, especially for chest radiograph or chest X-ray (CXR) screening, CXR image view information is required. Automatically separating CXR image view, frontal and lateral can ease subsequent CXR screening process, since the techniques may not equally work for both views. We presen...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-018-1786-3
更新日期:2018-08-01 00:00:00
abstract::The paper describes an investigation in which it is shown that small positive voltage pulses applied to an external conductor placed against the photocathode of a photomultiplier tube can be used to switch the photocathode completely off for the duration of the pulses. This suggests that a photomultiplier tube with a ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02441486
更新日期:1989-05-01 00:00:00
abstract::Osteoporosis is one of the most common diseases that leads to bone fractures. Dual-energy X-ray absorptiometry is currently employed to measure the bone mineral density and to diagnose osteoporosis. Alternatively, the dielectric properties of bones are found to be influenced by bone mineral density; hence, dielectric ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章,评审
doi:10.1007/s11517-018-1887-z
更新日期:2019-01-01 00:00:00
abstract::Conduct disorder (CD) is an important mental health problem in childhood and adolescence. There is presently a trend of revealing neural mechanisms using measures of brain networks. This study goes further by presenting a classification scheme to distinguish subjects with CD from typically developing healthy subjects ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-020-02215-8
更新日期:2020-09-01 00:00:00
abstract::This study describes a new method for analyzing microcirculatory videos. It introduces algorithms for quantitative assessment of vessel length, diameter, the functional microcirculatory density distribution and red blood-cell (RBC) velocity in individual vessels as well as its distribution. The technique was validated...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-008-0349-4
更新日期:2008-07-01 00:00:00
abstract::Over a period of some years, the components of a system for discerning erosion on children's teeth have been progressively developed, for use in an extensive project seeking correlations between erosion and various perceived risk factors. The aim was the detection of minute levels of erosion, based on mappings of the ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02348090
更新日期:2003-07-01 00:00:00
abstract::Spectral analysis of heart rate variability (HRV) is an accepted method for assessment of cardiac autonomic function and its relationship to numerous disorders and diseases. Various non-parametric methods for HRV estimation have been developed. The spectrum of counts, the instantaneous heart rate spectrum and the inte...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02524426
更新日期:1998-09-01 00:00:00
abstract::Neuronal excitability is determined in a complex way by several interacting factors, such as membrane dynamics, fibre geometry, electrode configuration, myelin impedance, neuronal terminations[Formula: see text] This study aims to increase understanding in excitability, by investigating the impact of these factors on ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-018-1799-y
更新日期:2018-09-01 00:00:00
abstract::Leukaemia is a type of blood cancer which mainly occurs when bone marrow produces excess white blood cells in our body. This disease not only affects adult but also is a common cancer type among children. Treatment of leukaemia depends on its type and how far the disease has spread in the body. Leukaemia is classified...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-020-02282-x
更新日期:2020-12-01 00:00:00
abstract::Based on the principle of backscattering of laser radiation from tissues, a non-invasive PC-AT based reflectance imaging technique is developed. The laser beam from a semiconductor laser operating at 670 nm is guided to the tissue site by an optical fibre. The backscattered radiation is collected by another fibre plac...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02530046
更新日期:1997-05-01 00:00:00
abstract::A bicuspid aortic valve (BAV) is a congenital cardiac disorder where the valve consists of only two cusps instead of three, as in a normal tricuspid valve (TAV). Although 97 % of BAVs include asymmetric cusps, little or no prior studies have investigated the blood flow through a three-dimensional BAV and root. The aim...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-013-1055-4
更新日期:2013-08-01 00:00:00
abstract::A computer-controlled pump for use both in the study of vascular haemodynamics and in the calibration of clinical devices which measure blood flow is designed. The novel design of this pump incorporates two rack-mounted pistons, driven into opposing cylinders by a micro-stepping motor. This approach allows the product...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02446086
更新日期:1991-11-01 00:00:00
abstract::Disturbed cerebrospinal fluid (CSF) dynamics are part of the pathophysiology of normal pressure hydrocephalus (NPH) and can be modified and treated with shunt surgery. This study investigated the contribution of established CSF dynamic parameters to AMP(mean), a prognostic variable defined as mean amplitude of cardiac...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-013-1110-1
更新日期:2014-01-01 00:00:00
abstract::Using images from the Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI), we developed a methodology for classifying lung nodules. The proposed methodology uses image processing and pattern recognition techniques. To classify volumes of interest into nodules and non-nodules, we used shape mea...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-016-1582-x
更新日期:2017-08-01 00:00:00
abstract::Preprocessing, binning and dataset subsampling are investigated with regard to simultaneous maximisation of the speed, accuracy and robustness of CT-3D rotational angiography (3DRA) registration. Clinical diagnosis and treatment can both take advantage of this integration, because 3DRA allows the shape of vessel struc...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02351041
更新日期:2005-09-01 00:00:00