Arterial reservoir-excess pressure and ventricular work.

Abstract:

:This study is based on the hypothesis that the pressure within the arterial network can be usefully decomposed as the sum of a reservoir pressure and an excess pressure. The reservoir pressure waveform is defined to be the same in each vessel but delayed by the wave travel time from the root of the aorta. Using calculus of variations and mass conservation, which relates the flow and rates of change of pressure in the vessels, we show that the reservoir pressure waveform minimises the ventricular hydraulic work for any physiologically or clinically reasonable ejection waveform and arterial properties, i.e. vessel compliances and terminal resistances. We conclude that the excess pressure determines the excess work done by the ventricle, which may have clinically important implications.

journal_name

Med Biol Eng Comput

authors

Parker KH,Alastruey J,Stan GB

doi

10.1007/s11517-012-0872-1

subject

Has Abstract

pub_date

2012-04-01 00:00:00

pages

419-24

issue

4

eissn

0140-0118

issn

1741-0444

journal_volume

50

pub_type

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