Abstract:
:A hypothetical neuromusculoskeletal model is developed to simulate human normal walking and its modulated behaviors. A small set of neural periodic patterns drive spinal muscle synergies which in turn lead to specific pattern of muscle activation and supraspinal feedback systems maintain postural balance during walking. Then, the model demonstrates modulated behaviors by superimposing voluntary perturbations on the underlying walking pattern. Motions of kicking a ball and obstacle avoidance during walking are simulated as examples. The superposition of the new pulse command to a set of invariant pulses representing spino-locomotor is sufficient to achieve the coordinated behaviors. Also, forward bent walking motion is demonstrated by applying similar superposition. The composition of activations avoids a complicated computation of motor program for a specific task and presents a simple control scheme for different walking patterns.
journal_name
Med Biol Eng Computjournal_title
Medical & biological engineering & computingauthors
Jo Sdoi
10.1007/s11517-007-0277-8subject
Has Abstractpub_date
2008-02-01 00:00:00pages
179-93issue
2eissn
0140-0118issn
1741-0444journal_volume
46pub_type
杂志文章abstract::Photoplethysmography imaging (PPGI) for non-contact monitoring of preterm infants in the neonatal intensive care unit (NICU) is a promising technology, as it could reduce medical adhesive-related skin injuries and associated complications. For practical implementations of PPGI, a region of interest has to be detected ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-020-02251-4
更新日期:2020-12-01 00:00:00
abstract::Protein glycosylation is one of the most important and complex post-translational modification that provides greater proteomic diversity than any other post-translational modification. Fast and reliable computational methods to identify glycosylation sites are in great demand. Two key issues, feature encoding and feat...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-015-1268-9
更新日期:2015-06-01 00:00:00
abstract::The mechanical impedance of the ankle joint during electrical stimulation of the soleus is studied by applying constant-velocity 10 degrees angular perturbations to the ankle and measuring the resultant torque. Both neurologically intact subjects and spinal cord injured subjects are tested. Lumped, piecewise linear mo...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02512522
更新日期:1994-05-01 00:00:00
abstract::Vertebral fractures are common in children with osteogenesis imperfecta (OI). Current imaging methods for fracture detection (X-ray and DXA) use ionising radiation. This pilot study explored whether the alteration in blood flow in vertebral fractures results in skin temperature changes that may be detected using high ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-018-1806-3
更新日期:2018-09-01 00:00:00
abstract::Computer-based simulations of human hip joints generally include investigating contacts happening among soft or hard tissues during hip movement. In many cases, hip movement is approximated as rotation about an estimated hip center. In this paper, we investigate the effect of different methods used for estimating hip ...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-012-0873-0
更新日期:2012-06-01 00:00:00
abstract::Tooth mobility examination is important in planning dental treatment, as it may give an indication of alveolar bone loss and the condition of the periodontal ligament. In clinical dental diagnosis a manual tooth mobility examination is useful. However, its determination of tooth mobility is subjective and depends on t...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02442173
更新日期:1989-01-01 00:00:00
abstract::A method for the estimation of medium rate transitions of non-stationary electroencephalograms (EEG) is proposed. The method is applicable to such EEG dynamics that are between (a) fast transitions for which segmentation procedures are used and (b) slow transitions for which adaptive filters work properly. The estimat...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02513305
更新日期:1999-05-01 00:00:00
abstract::Electrical and mechanical stimulation of the oesophagus has been recently proposed to examine the physiological effects of autonomic stimulation in humans. Cortical evoked potentials (EPs) to oesophageal stimulation provide an assessment of afferent fibres and central processing. However, habituation takes place durin...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02534088
更新日期:1997-07-01 00:00:00
abstract::Most tissues are subject to some form of physiological mechanical loading which results in deformation of the cells triggering intracellular mechanotransduction pathways. This response to loading is generally essential for the health of the tissue, although more pronounced deformation may result in cell and tissue dam...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章,评审
doi:10.1007/s11517-008-0381-4
更新日期:2008-10-01 00:00:00
abstract::Soleus muscle flap as coverage tissue is a possible surgical solution adopted to cover the wounds due to open fractures. Despite this procedure presents many clinical advantages, relatively poor information is available about the loss of functionality of triceps surae of the treated leg. In this study, a group of pati...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-020-02286-7
更新日期:2021-01-01 00:00:00
abstract::A method for extrapolating the extracellular water (ECW) resistance from wrist-ankle resistance at 50 kHz (R (50)) is proposed in this paper, in order to enable 50 kHz impedancemeters to use the BIS-Hanai equation for determination of ECW. Values of R (50) and the ECW resistance extrapolated at zero frequency R (e) we...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-008-0394-z
更新日期:2009-01-01 00:00:00
abstract::Left ventricular assist devices (LVAD) emerges as an effective clinical device providing life-saving support to heart patients. The design of blood pump of an LVAD involves incredible accuracy and thorough understanding of hemodynamics to mimic the functionality of a healthy ventricle. This work studies hemodynamics a...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-019-02097-5
更新日期:2020-02-01 00:00:00
abstract::Instantaneous backflow through central clearance of bileaflet heart valves at the instant of closure is investigated. An Edwards-Duromedics valve in the mitral position is employed to measure the transient pressures near the entrance and exit region in an in vitro flow chamber. A region surrounding the clearance is mo...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02510497
更新日期:1995-05-01 00:00:00
abstract::The aim of this study was to develop a radiation-free method to measure gastric emptying. Such a method would be useful e.g. for patients who need repeated measurements and in pregnancy. Ferrimagnetic particles (gamma-Fe2O3), ingested within a solid test meal (pancakes), were magnetised by an applied magnetic field. A...
journal_title:Medical & biological engineering & computing
pub_type: 临床试验,杂志文章
doi:10.1007/BF02522849
更新日期:1998-01-01 00:00:00
abstract::A building block-based software framework was developed to simulate electrophysiological networks. The synaptic potentials generated during neurotransmission were simulated in an existing discrete bidomain model of smooth muscle, using cubic, three-dimensional grids of varying sizes. The model is automatically derived...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345322
更新日期:2003-09-01 00:00:00
abstract::Bone mass and microarchitecture are the main determinants of bone strength. Three-dimensional micro-computed tomography has the potential to examine complete bones of small laboratory animals with very high resolution in a non-invasive way. In the presented work, the proximal part of the tibiae of hindlimb unloaded an...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02347054
更新日期:2000-05-01 00:00:00
abstract::The accelerometer is used for mechanomyogram (MMG) recordings of muscle contractions. Although the mechanical characteristics of other MMG transducers have been determined with reference to the accelerometer, mechanical aspects of the accelerometer itself, including the weight of the transducer, have not been verified...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02344888
更新日期:2003-03-01 00:00:00
abstract::The purpose of this study was to evaluate the effect of increased blood flow on angiogenesis at the large vessels. The arteriovenous (AV) shunt was made on the thigh of male Wistar rats (n = 27) to increase blood flow, wrapped with artificial skin dermis, which consisted of a silicon outer layer, and isolated from sur...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345133
更新日期:2005-01-01 00:00:00
abstract::The aim of the study is to determine the effects of wound, patient and treatment attributes on the wound healing rate and to propose a system for wound healing rate prediction. Predicting the wound healing rate from the initial wound, patient and treatment data collected in a database of 300 chronic wounds is not poss...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02345144
更新日期:2001-09-01 00:00:00
abstract::Due to its capabilities in analysing injury risk, the ability to analyse an athlete's ground reaction force and joint moments is of high interest in sports biomechanics. However, using force plates for the kinetic measurements influences the athlete's performance. Therefore, this study aims to use a feed-forward neura...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-019-02000-2
更新日期:2019-08-01 00:00:00
abstract::Gait disturbances are common in the rat model of Parkinson's disease (PD) by administrating 6-hydroxydopamine. However, few studies have simultaneously assessed spatiotemporal gait indices and the kinematic information of PD rats during overground locomotion. This study utilized a simple, accurate, and reproducible me...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-012-0933-5
更新日期:2012-09-01 00:00:00
abstract::Time-varying filtering techniques are applied to the problem of baseline correction by letting the cut-off frequency of a linear filter be controlled by the low-frequency properties of the ECG signal. The time-varying filter is implemented as a bank of linear low-pass filters, in which each filter has a slightly diffe...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02441986
更新日期:1993-09-01 00:00:00
abstract::The development of an active implantable device for measuring electrocardiogram (ECG) is presented. The study is a part of a project which aims at developing implantable ECG instrumentation with wireless data and power transfer ( http://www.ele.tut.fi/tule ). The developed implant presented here has all the measuremen...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章,评审
doi:10.1007/s11517-007-0264-0
更新日期:2007-12-01 00:00:00
abstract::We introduce a novel method for an automatic classification of subjects to those with or without neuromuscular disorders. This method is based on multiscale entropy of recorded surface electromyograms (sEMGs) and support vector classification. The method was evaluated on a single-channel experimental sEMGs recorded fr...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-010-0629-7
更新日期:2010-08-01 00:00:00
abstract::The long QT syndrome (LQTS) is a genetic disorder, typically characterized by a prolonged QT interval in the ECG due to abnormal cardiac repolarization. LQTS may lead to syncopal episodes and sudden cardiac death. Various parameters based on T-wave morphology, as well as the QT interval itself have been shown to be us...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-006-0061-1
更新日期:2006-07-01 00:00:00
abstract::The three-dimensional changes in the cytoskeleton and in cell proliferation of bovine pulmonary artery endothelial cells when exposed to sustained hydrostatic pressure were investigated in vitro using laser scanning confocal microscopy. Subconfluent endothelial cells on rigid substrates were exposed to 1.5, 5 and 10 c...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02523225
更新日期:1998-07-01 00:00:00
abstract::The aim of the study was to develop a method for investigating how interictal epileptic discharges in temporal epilepsy patients are activated spatially. The activity was measured using magneto-encephalography (MEG). The MEG data were used to produce a current-arrow map that reflected the topographic distribution of t...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/BF02344215
更新日期:2002-05-01 00:00:00
abstract::It is of great importance to effectively process and interpret surface electromyogram (sEMG) signals to actuate a robotic and prosthetic exoskeleton hand needed by hand amputees. In this paper, we have proposed a cepstrum analysis-based method for classification of basic hand movement sEMG signals. Cepstral analysis t...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-019-02024-8
更新日期:2019-10-01 00:00:00
abstract::Calcific aortic valve disease (CAVD) is characterized by calcification accumulation and thickening of the aortic valve cusps, leading to stenosis. The importance of fluid flow shear stress in the initiation and regulation of CAVD progression is well known and has been studied recently using fluid-structure interaction...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-016-1458-0
更新日期:2016-11-01 00:00:00
abstract::Partial coherence estimate between two signals removing the contribution of a periodic, deterministic one is proposed for measuring the coherence between two ongoing eletroencephalografic (EEG) activities collected at distinct cortical regions under sensory stimulation. The estimator expression was derived and shown t...
journal_title:Medical & biological engineering & computing
pub_type: 杂志文章
doi:10.1007/s11517-007-0191-0
更新日期:2007-07-01 00:00:00