Can the extent of epicardial adipose tissue thickness or the presence of descending thoracic aortic calcification predict significant coronary artery stenosis in patients with a zero coronary calcium score on multi-detector CT?

Abstract:

OBJECTIVE:The purpose of this study was to evaluate whether the extent of epicardial adipose tissue (EAT) thickness or the presence of descending thoracic aortic calcification on multi-detector CT (MDCT) can predict the presence of significant coronary artery stenosis in patients with negative coronary artery calcium (CAC). METHODS:We enrolled 90 patients with negative CAC in whom both coronary CT angiography (CTA) and conventional angiography had been performed. Group 1 consisted of patients (n=27) with significant coronary artery stenosis (≥50%), whereas group 2 (n=63) had non-obstructive coronary artery stenosis (<50%) on conventional angiography. We analyzed whether or not there is a significant difference in EAT thickness or the incidence of calcification of descending thoracic aorta among the two groups. RESULTS:There was no significant difference between EAT thickness on MDCT among the two groups. There was also no significant difference in the incidence of descending thoracic aortic calcification between group 1 (7/27, 25.9%) and group 2 (14/63, 22.2%) (p>0.05). CONCLUSIONS:Neither the presence of abundant EAT nor calcification of descending thoracic aorta is a marker of significant coronary artery stenosis in patients with negative CAC.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

Lee HY,Song IS,Yoo SM,Rho JY,Moon JY,White CS

doi

10.1016/j.atherosclerosis.2010.01.047

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

495-500

issue

2

eissn

0021-9150

issn

1879-1484

pii

S0021-9150(10)00096-1

journal_volume

212

pub_type

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