Chemokine expression in coronary circulation after coronary angioplasty as a prognostic factor for restenosis.

abstract：OBJECTIVES:We conducted a meta-analysis of relevant randomized trials to assess whether folic acid supplementation reduces the progression of atherosclerosis as measured by carotid intima-media thickness (CIMT). METHODS:This analysis included 2052 subjects from ten folic acid randomized trials with the change in CIMT ...

journal_title：Atherosclerosis

authors： Qin X,Xu M,Zhang Y,Li J,Xu X,Wang X,Xu X,Huo Y

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:HIV+ patients are at increased risk of cardiovascular disease (CVD). Inflammation plays a role in adults, but has not yet been assessed in HIV+ children. We compared proinflammatory cytokines and adhesion molecules in HIV+ children versus healthy controls, and assessed their relationship to carotid intima-me...

journal_title：Atherosclerosis

authors： Ross AC,O'Riordan MA,Storer N,Dogra V,McComsey GA

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Smoking is associated with increased postprandial hypertriglyceridemia (PPT). Inflammation and insulin resistance are potential "drivers" for this phenomenon. We tested whether inflammatory patterns and/or insulin resistance explain the effect of smoking on PPT. METHODS AND RESULTS:Men and women in the NHLB...

journal_title：Atherosclerosis

authors： Kabagambe EK,Ordovas JM,Tsai MY,Borecki IB,Hopkins PN,Glasser SP,Arnett DK

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Abdominal aortic aneurysms (AAA) is a chronic inflammatory disease in which signal transducer and activator of transcription 3 (STAT3), and disintegrin and metalloproteinase 17 (ADAM17) play important roles. However, it remains unclear whether ursolic acid (UA), a natural pentacyclic triterpenoid ca...

journal_title：Atherosclerosis

authors： Zhai M,Guo J,Ma H,Shi W,Jou D,Yan D,Liu T,Tao J,Duan J,Wang Y,Li S,Lv J,Li C,Lin J,Zhang C,Lin L

更新日期：2018-04-01 00:00:00

abstract：:Lack of physical activity appears to have deleterious effects on serum lipoproteins. Twenty-three patients who were completely immobilised by traumatic fracture of the spine had significantly lower (P < 0.001) plasma high density lipoprotein cholesterol (HDL-C) and apolipoprotein A-I levels than normally mobile paired...

journal_title：Atherosclerosis

authors： Nikkilä EA,Kuusi T,Myllynen P

更新日期：1980-11-01 00:00:00

abstract：OBJECTIVE:To examine whether genetic polymorphisms in the 5-lipoxygenase activating protein (ALOX5AP) confer an increased risk to angiographically proven coronary artery disease (CAD) in a case-control study of a Midwestern population in the US. METHODS:We genotyped 7 SNPs (SG13S25, SG13S89, SG13S41, SG13S377, SG13S35...

journal_title：Atherosclerosis

authors： Tsai AK,Li N,Hanson NQ,Tsai MY,Tang W

更新日期：2009-12-01 00:00:00

abstract：:We studied the effect of lysolecithin on the clearing of plasma cholesterol. The immediate and maximal conversion of plasma lecithin to lysolecithin was produced in rats by intravenous injection of phospholipase A. The changes which took place in the converted lysolecithin and of cholesterol were followed in rats whic...

journal_title：Atherosclerosis

authors： Dobiásová M,Faltová E,Marek J,Obenberger J

更新日期：1975-05-01 00:00:00

abstract：:Advanced glycation end-products (AGEs), a group of carbohydrate-derived compounds formed by non-enzymatic glycation and oxidation, are markedly elevated in end-stage renal disease (ESRD) and may be related to both inflammation and oxidative stress. The cellular effects of AGE are largely mediated by their interaction ...

journal_title：Atherosclerosis

authors： Rodríguez-Ayala E,Anderstam B,Suliman ME,Seeberger A,Heimbürger O,Lindholm B,Stenvinkel P

更新日期：2005-06-01 00:00:00

abstract：:Two preparations active in reducing hepatic cholesterolgenesis in vitro were demonstrated in human milk. These appear to affect the cholesterol synthetic pathway at different loci. One inhibits the synthesis before the formation of mevalonic acid and has been isolated and subsequently identified as uric acid. The othe...

journal_title：Atherosclerosis

authors： Ward PC,McCarthy RD,Kilara A

更新日期：1982-02-01 00:00:00

abstract：:Inflammation has been demonstrated to be an important risk factor for the development of cardiovascular events. Patients with elevated white blood cell counts have been shown to be in a higher risk of developing acute myocardial infarction and acute coronary and vascular events. We review the clinical data of high whi...

journal_title：Atherosclerosis

authors： Hoffman M,Blum A,Baruch R,Kaplan E,Benjamin M

更新日期：2004-01-01 00:00:00

abstract：:Apolipoprotein E (apoE) exerts prominent anti-inflammatory effects and undergoes recycling by target cells. We previously reported that the peptide Ac-hE18A-NH(2), composed of the receptor binding domain (LRKLRKRLLR) of apoE covalently linked to the Class A amphipathic peptide 18A, dramatically lowers plasma cholester...

journal_title：Atherosclerosis

authors： Datta G,White CR,Dashti N,Chaddha M,Palgunachari MN,Gupta H,Handattu SP,Garber DW,Anantharamaiah GM

更新日期：2010-01-01 00:00:00

abstract：:Since VLDL and LDL are involved in atherogenesis, their response to dietary modification was studied in 15 normal male prisoners. A 3-month reference diet (P/S ratio 0.3, daily cholesterol intake 370 mg) was compared with a modified fat diet (P/S 1.0, 250 mg) given for further 3 months. The decrement in serum choleste...

journal_title：Atherosclerosis

authors： Weisweiler P,Drosner M,Janetschek P,Schwandt P

更新日期：1983-12-01 00:00:00

abstract：:The levels, isoforms and distribution of apolipoprotein A-IV (apo A-IV) were investigated in 127 term human umbilical cord sera. In addition, apo A-IV levels and isoforms were determined on the 3rd (n = 82) and 6th (n = 68) day following parturition and compared to apo A-I concentrations. Levels of apo A-IV were low i...

journal_title：Atherosclerosis

authors： Steinmetz A,Czekelius P,Thiemann E,Motzny S,Kaffarnik H

更新日期：1988-01-01 00:00:00

abstract：:The role of endothelium-derived nitric oxide (NO) in modulation of large artery stiffness in patients with peripheral arterial disease (PAD) is unexplored. The aim of this study was to evaluate, using pulse wave analysis (PWA), changes in aortic and systemic arterial stiffness following administration of nitroglycerin...

journal_title：Atherosclerosis

authors： Kals J,Kampus P,Kals M,Pulges A,Teesalu R,Zilmer M

更新日期：2006-04-01 00:00:00

abstract：:The ability of triglyceride (TG)-rich lipoproteins from apolipoprotein (apo) E2 heterozygote, apo E3/2 which is relatively common, to stimulate cholesteryl ester synthesis in human monocyte-derived macrophages was studied to clarify the atherogenicity of apo E3/2. Twenty-three subjects were randomly sampled from our h...

journal_title：Atherosclerosis

authors： Saito M,Eto M,Makino I

更新日期：1997-02-28 00:00:00

abstract：:The effect of guar (15.6 g/day), a dietary fibre, and simultaneous administration of bezafibrate (600 mg/day) during dietetic treatment on the plasma lipoproteins and apolipoproteins was investigated in 12 patients with familial hypercholesterolemia (corresponding to the HLP type IIa pattern). Either bezafibrate alone...

journal_title：Atherosclerosis

authors： Wirth A,Middelhoff G,Braeuning C,Schlierf G

更新日期：1982-12-01 00:00:00

abstract：:The effects of administration of pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, on hepatic cholesterol 7 alpha-hydroxylase and acyl-coenzyme A: cholesterol acyltransferase (ACAT) activities and bile lipid secretion were investigated in Syrian golden hamsters. Continuous administrat...

journal_title：Atherosclerosis

authors： Hayashi K,Noshiro M,Kurushima H,Kuga Y,Nomura S,Ohkura Y,Ohtani H,Kurokawa J,Tanaka K,Yasunobu Y

更新日期：1994-12-01 00:00:00

abstract：:The association between cigarette smoking and atherogenesis is well established. Inflammatory cells may participate in atherogenesis via activation of the NADPH oxidase and the subsequent production of reactive oxygen species (ROS), which exacerbates endothelial injury. However, little is known about the ability of ci...

journal_title：Atherosclerosis

authors： Dunn JS,Freed BM,Gustafson DL,Stringer KA

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:Being the earliest step on the way to atherosclerosis, endothelial dysfunction is particularly escalated in diabetes. This study aimed at assessing endothelial dysfunction and blood pressure disturbances in young patients with type 1 diabetes mellitus (T1DM) and defining their interrelations. METHODS:The stu...

journal_title：Atherosclerosis

authors： Machnica L,Deja G,Polanska J,Czupryniak L,Szymanska-Garbacz E,Loba J,Jarosz-Chobot P

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:25-Hydroxycholesterol (25HC) and its sulfated metabolite, 25-hydroxycholesterol-3-sulfate (25HC3S), regulate certain aspects of lipid metabolism in opposite ways. Hence, the enzyme for the biosynthesis of 25HC3S, oxysterol sulfotransferase (SULT2B1b), may play a crucial role in regulating lipid metabolism. We...

journal_title：Atherosclerosis

authors： Bai Q,Xu L,Kakiyama G,Runge-Morris MA,Hylemon PB,Yin L,Pandak WM,Ren S

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Heterozygous familial hypercholesterolemia (heFH) is a common autosomal dominant hereditary disorder caused by mutations in the LDL-receptor gene that lead to elevated plasma levels of low-density lipoprotein-cholesterol (LDL-c). Robust lowering of LDL-c levels is essential for risk reduction of premature ca...

journal_title：Atherosclerosis

authors： Pijlman AH,Huijgen R,Verhagen SN,Imholz BP,Liem AH,Kastelein JJ,Abbink EJ,Stalenhoef AF,Visseren FL

更新日期：2010-03-01 00:00:00

abstract：:Inflammatory response genes may influence life span or quality at advanced ages. Using data from the population-based cardiovascular health study (CHS) cohort, we examined the associations between promoter polymorphisms of several inflammation and thrombosis genes with longevity. We ascertained genotypes for interleuk...

journal_title：Atherosclerosis

authors： Reiner AP,Diehr P,Browner WS,Humphries SE,Jenny NS,Cushman M,Tracy RP,Walston J,Lumley T,Newman AB,Kuller LH,Psaty BM

更新日期：2005-07-01 00:00:00

abstract：:The relations between triglyceride-rich lipoproteins, alimentary lipaemia and coronary heart disease (CHD) have remained obscure and much debated. We studied the basal and postprandial plasma levels of chylomicron remnants and very low density lipoproteins (VLDL) of varying particle size in 32 male postinfarction pati...

journal_title：Atherosclerosis

authors： Karpe F,Steiner G,Uffelman K,Olivecrona T,Hamsten A

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:To investigate the hypothesis that COMP can influence the morphology, stability and size of murine atherosclerotic lesions. METHODS:ApoE- and ApoE/COMP-knockout mice were fed a high-fat diet to develop atherosclerotic plaques at lesion sites of three different types; inflammatory and fibrous plaques induced ...

journal_title：Atherosclerosis

authors： Bond AR,Hultgårdh-Nilsson A,Knutsson A,Jackson CL,Rauch U

更新日期：2014-10-01 00:00:00

abstract：:In order to obtain information about the developmental mechanisms of restenosis after angioplasty, we investigated an association between the expression of platelet-derived growth factors (PDGFs) and neointimal cell accumulation in rabbit femoral arteries subjected to balloon angioplasty. Northern analysis demonstrate...

journal_title：Atherosclerosis

authors： Uchida K,Sasahara M,Morigami N,Hazama F,Kinoshita M

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:The objective of the present study was to investigate the effects of one-year treatment with exenatide or Insulin Glargine, followed by a 5-week off-drug period, on postprandial lipidaemia, glycaemia and measures of oxidative stress. METHODS:Sixty-nine metformin-treated patients with type 2 diabetes were ran...

journal_title：Atherosclerosis

authors： Bunck MC,Cornér A,Eliasson B,Heine RJ,Shaginian RM,Wu Y,Yan P,Smith U,Yki-Järvinen H,Diamant M,Taskinen MR

更新日期：2010-09-01 00:00:00

abstract：:beta-Oxidation of long-chain fatty acids increases many-fold in atherosclerotic aortas; this may be due to an increase in the activity of the mitochondrial enzyme hexadecanoyl-CoA: carnitine O-hexadecanoyltransferase EC 2.3.1.23 (trivial name: carnitine palmitoyltransferase, CPT). To investigate this possibility, an a...

journal_title：Atherosclerosis

authors： Gillies PJ,Bell FP

更新日期：1979-09-01 00:00:00

abstract：OBJECTIVE:Obesity and cardiovascular disease recognize a common metabolic soil and may therefore share part of their genetic background. Genome-wide association studies have identified variability at the SH2B1 locus as a predictor of obesity. We investigated whether SNP rs4788102, which captures the entire SH2B1 variab...

journal_title：Atherosclerosis

authors： Prudente S,Morini E,Larmon J,Andreozzi F,Di Pietro N,Nigro A,Gervino EV,Mannino GC,Bacci S,Hauser TH,Bellacchio E,Formoso G,Pellegrini F,Proto V,Menzaghi C,Frittitta L,Pandolfi A,Sesti G,Doria A,Trischitta V

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Dysregulation of long non-coding RNAs (lncRNAs) has been proven to be involved in the pathogenesis of coronary artery disease (CAD). However, it remains to be extensively explored. Thus, the present study aims to study expression patterns, biological functions, and diagnostic value of lncRNAs in CAD...

journal_title：Atherosclerosis

authors： Li L,Wang L,Li H,Han X,Chen S,Yang B,Hu Z,Zhu H,Cai C,Chen J,Li X,Huang J,Gu D

更新日期：2018-08-01 00:00:00

abstract：:This study examined the effects of lovastatin supplementation (25 mg/kg per day) in conjunction with an atherogenic diet (10% coconut oil (w/w), 0.05% cholesterol) on regression of pre-existing foam cells and on hepatic and intestinal LDL receptor and HMG CoA reductase mRNA levels. F1B hamsters fed the atherogenic die...

journal_title：Atherosclerosis

authors： Pitman WA,Osgood DP,Smith D,Schaefer EJ,Ordovas JM

更新日期：1998-05-01 00:00:00