Relevance of DNA alkylation damage repair systems in Salmonella enterica virulence.

Abstract:

:Systematic inactivation of pathways involved in DNA alkylation damage repair demonstrated that inactivation of the ada, ogt, tag, uvrA, and mfd genes is required to detect a Salmonella enterica virulence decrease. Furthermore, the fitness of S. enterica, defective in these genes, is lowered only when the bacterium is orally, but not intraperitoneally, inoculated.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Alvarez G,Campoy S,Spricigo DA,Teixidó L,Cortés P,Barbé J

doi

10.1128/JB.01693-09

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

2006-8

issue

7

eissn

0021-9193

issn

1098-5530

pii

JB.01693-09

journal_volume

192

pub_type

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