Ontogenesis of the depressant activity of carbachol on synaptic activity in rat visual cortex.

abstract：:Inferior olive neurons, in brain slices maintained in vitro, display spontaneous, continuous oscillations of their membrane potential which are consonant with olivary rhythmic activity seen in vivo. This oscillatory behavior was studied with intracellular electrophysiological techniques. The 3-10 Hz rhythmicity of the...

journal_title：Brain research bulletin

authors： Benardo LS,Foster RE

更新日期：1986-12-01 00:00:00

abstract：:The lateral hypothalamic area (LHA) and globus pallidus (GP) are basically involved in the regulation of feeding and metabolic processes. In the LHA, glucose-sensitive (GS) neurons were described: their activity was found to be specifically suppressed by electrophoretic application of glucose, and these neurons appear...

journal_title：Brain research bulletin

authors： Lénárd L,Karádi Z,Faludi B,Czurkó A,Niedetzky C,Vida I,Nishino H

更新日期：1995-01-01 00:00:00

abstract：:This investigation assessed the relative reliability of the human auditory evoked potential (AEP) amplitude-intensity and latency-intensity functions. Averaged AEP waveforms to 10 levels of stimulus magnitude were obtained from bipolar recordings. Variability and slope of group functions were constant, as indicated by...

journal_title：Brain research bulletin

authors： Browman CP,Sullivan HT

更新日期：1980-03-01 00:00:00

abstract：:Our previous study demonstrated that single intrathecal (i.t.) application of fluorocitrate, a glial metabolic inhibitor, synergized electroacupuncture (EA) antagonizing behavioral hypersensitivity in complete Freund's adjuvant (CFA)-induced monoarthritic rat. To further investigate the relationship between spinal gli...

journal_title：Brain research bulletin

authors： Sun S,Cao H,Han M,Li TT,Zhao ZQ,Zhang YQ

更新日期：2008-01-31 00:00:00

abstract：:The acute effects of 2-deoxy-D-glucose (2-DG)-induced glucoprivic feeding on the anorectic drug recognition site and Na+K(+)-ATPase in the brain were examined in adult rats and in lean and genetically obese mice. The marked hyperglycemia and the induction of feeding caused by the administration of 2-DG to satiated rat...

journal_title：Brain research bulletin

authors： Angel I,Hauger RL,Giblin BA,Paul SM

更新日期：1992-02-01 00:00:00

abstract：:Hoe 065 is a compound structurally related to the angiotensin converting enzyme inhibitors and capable of increasing central cholinergic activity. The effects of this compound were studied on alcohol intake and on the reduction in alcohol intake produced by abutapril, an angiotensin converting enzyme inhibitor. Hoe 06...

journal_title：Brain research bulletin

authors： Grupp LA,Chow SY

更新日期：1991-04-01 00:00:00

abstract：OBJECTIVE:To explore the unified and disease specific structural features of the brain in patients spanning six mental disorders who experience own-thought auditory verbal hallucinations (OTAVH). METHODS:A pilot study was conducted on 25 patients with schizophrenia (FUSCH-OTAVH), 20 patients with major depression diso...

journal_title：Brain research bulletin

authors： Zhuo C,Lin X,Wang C,Song X,Xu X,Li G,Xu Y,Tian H,Zhang Y,Wang W,Zhou C

更新日期：2020-07-01 00:00:00

abstract：:Adaptation of the frog, Rana temporaria, to a white background for 12 hr has resulted in an intense formaldehyde-induced fluorescence (FIF) in the neurons of the preoptic recess organ (PRO), paraventricular organ (PVO), nucleus infundibularis dorsalis (NID) and their basal processes permitting visualization of the PRO...

journal_title：Brain research bulletin

authors： Prasada Rao PD

更新日期：1982-07-01 00:00:00

abstract：:Peroxynitrite (ONOO-) is a strong biological oxidant formed by the diffusion-limited reaction of nitric oxide (NO-) and superoxide anion (O2-). It has long been theorized that peroxynitrite generation could be the cause in a number of pathological conditions ranging from atherosclerosis to inflammatory, autoimmune, he...

journal_title：Brain research bulletin

authors： Ramdial K,Franco MC,Estevez AG

更新日期：2017-07-01 00:00:00

abstract：:In accordance with the genetic nature of Huntington's disease (HD), transgenic and knock-in mouse models have been developed that have sought to recapitulate the key features of the human condition. To date, only a single rat model has been developed, the tgHD rat that carries 51 CAG repeats. The tgHD rat has many of ...

journal_title：Brain research bulletin

authors： Brooks S,Fielding S,Döbrössy M,von Hörsten S,Dunnett S

更新日期：2009-06-30 00:00:00

abstract：:To determine whether or not prolactin, as well as ACTH, was involved in the control of adrenal weight and steroid release, lesions in the median eminence which had previously resulted in impaired steroid release and atrophy of the adrenal were placed in animals in which the plasma prolactin was allowed to rise as a re...

journal_title：Brain research bulletin

authors： Marubayashi U,McCann SM,Antunes-Rodrigues J

更新日期：1987-11-01 00:00:00

abstract：:The failure of regenerating axons to grow within the adult mammalian central nervous system (CNS) does not apply to the olfactory bulb (OB). In this structure, normal and transected olfactory axons are able to enter, regenerate, and reestablish lost synaptic contacts with their targets, throughout the lifetime of the ...

journal_title：Brain research bulletin

authors： Ramón-Cueto A,Avila J

更新日期：1998-06-01 00:00:00

abstract：:Single-nucleotide polymorphism (SNP) and Alternative splicing (AS) were found to be implicated in certain diseases, nevertheless, the contributions of mRNA SNPs and AS to pathogenesis in developing rat brains with hypoxic-ischemic encephalopathy (HIE) remained largely vague. Additionally, the disease associated with T...

journal_title：Brain research bulletin

authors： Xue LL,Wang F,Xiong LL,Du RL,Zhou HL,Zou Y,Wu MX,Yang MA,Dai J,He MX,Wang TH

更新日期：2020-01-01 00:00:00

abstract：:Space motion sickness (SMS) and spatial orientation and motion perception disturbances occur in 70-80% of astronauts. People select "rest frames" to create the subjective sense of spatial orientation. In microgravity, the astronaut's rest frame may be based on visual scene polarity cues and on the internal head and bo...

journal_title：Brain research bulletin

authors： Harm DL,Parker DE,Reschke MF,Skinner NC

更新日期：1998-11-15 00:00:00

abstract：:Early life Stress is a worldwide concern linked with development of later life neurological disorders. Early developmental age is sensitive to many prominent environmental insults like malnourishment, immune inflammation, abuse, maternal separation, alcohol and drugs. Hence, an individual during an early age encounter...

journal_title：Brain research bulletin

authors： Sarkar T,Patro N,Patro IK

更新日期：2019-04-01 00:00:00

abstract：:The processing of amyloid precursor protein (APP) to amyloid beta (Aβ) is of great interest to the Alzheimer's disease (AD) field. Decades of research define how APP is altered to form Aβ, and how Aβ generates oligomers, protofibrils, and fibrils. Numerous signaling pathways and changes in cell physiology are known to...

journal_title：Brain research bulletin

authors： Wilkins HM,Swerdlow RH

更新日期：2017-07-01 00:00:00

abstract：:We examined effects of omega-conotoxin previously known as a selective blocker of N-type calcium channels, on the adenosine triphosphate (ATP)-induced currents in the rat dorsal root ganglion neurons. These neurons express at least two types of ionotropic purinoreceptors: P2X3 receptors that have very rapid desensitiz...

journal_title：Brain research bulletin

authors： Lalo UV,Pankratov YV,Arndts D,Krishtal OA

更新日期：2001-03-15 00:00:00

abstract：BACKGROUND:Statins are cholesterol lowering drugs that decrease the risk of cardiovascular events, but they are related with a few unfavorable symptoms in skeletal muscle including myopathy, and mild to moderate fatigue. Additionally, there has been discrepancies about the impacts of statins on brain and cognition. Thi...

journal_title：Brain research bulletin

authors： Okudan N,Belviranli M

更新日期：2020-12-01 00:00:00

abstract：:Single-unit responses of preoptic-anterior hypothalamic (PO/AH) thermosensitive neurons to electrical stimulation of the mediobasal hypothalamus (MBH: ventromedial and arcuate nuclei) have been studied in urethane-anesthetized male rats. About half of thermosensitive neurons (46.4% of 69 warm-units and 50% of 28 cold-...

journal_title：Brain research bulletin

authors： Hori T,Kiyohara T,Osaka T,Shibata M,Nakashima T

更新日期：1982-06-01 00:00:00

abstract：:Waxing and waning electrographic responses (augmenting) and primary evoked responses could be induced in restricted regions of hippocampus, thalamus, and skeletal muscle by bipolar, low-frequency (7-10 Hz), low-amplitude (35 mV-4V) stimulation of selected sites within the hippocampus or thalamus of rabbits. Induction ...

journal_title：Brain research bulletin

authors： Palmer MR,Klemm WR

更新日期：1977-03-01 00:00:00

abstract：:Neurological assessment of certain movement disorders is described with emphasis on Parkinson's disease. In addition, abnormal behavior and changes in affect are given. Changes in neurological status, i.e., Bradykinesia, rigidity, gait changes, hand-writing irregularity, postural reflexes are outlined. The differentia...

journal_title：Brain research bulletin

authors： Byer JA,Dexter JD

更新日期：1983-08-01 00:00:00

abstract：:Brain cytokines have been implicated in brain plasticity and mood alterations. We present here the first evidence of a chronic stress-induced modulation of central cytokines, in absence of experimentally induced inflammatory processes. Several brain areas were extracted from stressed and control mice and cytokines mRN...

journal_title：Brain research bulletin

authors： Bartolomucci A,Palanza P,Parmigiani S,Pederzani T,Merlot E,Neveu PJ,Dantzer R

更新日期：2003-12-30 00:00:00

abstract：:A new silver method for senile plaques and neurofibrillary tangles (NFT) in paraffin sections is presented. This new technique is rapid in execution (15 min) and reveals senile plaques of all morphological types as well as NFT. The silver staining is spatially congruent with immunocytochemical staining for the beta-am...

journal_title：Brain research bulletin

authors： Hedreen JC,Raskin LS,Price DL

更新日期：1994-01-01 00:00:00

abstract：:In this study, we examine the utility of computational modeling in understanding nervous system function. We start by examining the reasons for, and major approaches to, computational modeling. We then chose a modeling approach and applied different variations to understanding nucleus tractus solitarius (NTS) neuronal...

journal_title：Brain research bulletin

authors： Rogers RF,Rybak IA,Schwaber JS

更新日期：2000-01-15 00:00:00

abstract：:Locomotor performance of transgenic R6/2 mice carrying the Huntington's disease (HD) mutation was assessed using four different tasks, fixed speed rotarod, accelerating rotarod, Digigait and footprint test. The tasks were compared directly in age- and CAG repeat-matched R6/2 mice. Accelerating rotarod was more sensiti...

journal_title：Brain research bulletin

authors： Pallier PN,Drew CJ,Morton AJ

更新日期：2009-03-30 00:00:00

abstract：:After placing bilateral electrolytic lesions in the fasciculus retroflexus (FR) of the rat, the endogenous content of serotonin, glutamate and gamma-aminobutyrate (GABA) as well as choline acetyltransferase activity (ChAT) were measured in the interpeduncular nucleus (IPN) at the 7th, 28th and 120th survival days. Con...

journal_title：Brain research bulletin

authors： Takishita N,Kubo H,Mitani A,Nakamura Y,Masuda S,Iwahashi K,Kataoka K

更新日期：1990-10-01 00:00:00

abstract：:Some C57Bl/6 mice become obese, whereas others remain lean when raised on a high-fat diet. The mechanisms underlying this interindividual susceptibility to diet-induced obesity remain unknown. Because hypothalamus plays a major role in the regulation of body weight, this study was conducted to identify the differences...

journal_title：Brain research bulletin

authors： Xin X,Storlien LH,Huang XF

更新日期：2000-07-01 00:00:00

abstract：:Several works have shown that males and females differ in the ability to learn spatial locations in mazes. In this study, we used the Morris water maze to assess the acquisition of a spatial working memory (WM) task in adult male and female Wistar rats. The task consisted of a paired sample procedure made up of two da...

journal_title：Brain research bulletin

authors： Méndez-López M,Méndez M,López L,Arias JL

更新日期：2009-05-29 00:00:00

abstract：:Proneuropeptide Y (proNPY) is posttranslationally processed to NPY(1-36)amide and the C-terminal flanking peptide of NPY (CPON). Antisera directed against the N-terminal part of NPY, CPON, or CysNPY(32-36)amide were used to identify peptide fragments processed from proNPY in biopsies of human frontal cortical specimen...

journal_title：Brain research bulletin

authors： Mikkelsen JD,Larsen PJ,Kruse-Larsen C,O'Hare MM,Schwartz TW

更新日期：1993-01-01 00:00:00

abstract：:Maternal immune activation during pregnancy is a risk factor for neurodevelopmental disorders, such as schizophrenia; however, a full mechanistic understanding has yet to be established. The activity of a transient cell population, the subplate neurons, is critical for the development of cortical inhibition and functi...

journal_title：Brain research bulletin

authors： Beamer E,Kovács G,Sperlágh B

更新日期：2017-10-01 00:00:00