RECQL5 helicase: connections to DNA recombination and RNA polymerase II transcription.

Abstract:

:The RecQ family of helicases are traditionally viewed as recombination factors, important for maintaining genome stability. RECQL5 is unique among these proteins in being associated with RNA polymerase II, the enzyme responsible for transcribing all protein-encoding genes in eukaryotes. Here, we describe the possible implications of recent studies and discuss models for RECQL5 function.

journal_name

DNA Repair (Amst)

journal_title

DNA repair

authors

Aygün O,Svejstrup JQ

doi

10.1016/j.dnarep.2009.12.008

subject

Has Abstract

pub_date

2010-03-02 00:00:00

pages

345-53

issue

3

eissn

1568-7864

issn

1568-7856

pii

S1568-7864(09)00336-X

journal_volume

9

pub_type

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