Luteinizing hormone increases platelet-derived growth factor-D gene expression in human granulosa-luteal cells.

Abstract:

:We aimed to investigate the effects of LH and FSH on the gene expression of the platelet-derived growth factor (PDGF) gene family in human granulosa-luteal cells. We found that LH significantly increased PDGF-D messenger RNA (mRNA) expression but suppressed PDGF-B and PDGF-C mRNA in human granulosa-luteal cells, and FSH also increases PDGF-D gene expression, but to a lesser extent.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Hwu YM,Li SH,Lee RK,Lin MH,Tsai YH,Yeh TS

doi

10.1016/j.fertnstert.2009.05.064

subject

Has Abstract

pub_date

2009-12-01 00:00:00

pages

2065-8

issue

6

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(09)01212-6

journal_volume

92

pub_type

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