Abstract:
OBJECTIVE:To compare zygote intrafallopian transfer (ZIFT) and in vitro fertilization and embryo transfer (IVF-ET) as treatments of male-factor infertility. DESIGN:Patients were prospectively randomized to ZIFT or IVF-ET. SETTING:In vitro fertilization program of the Centre for Reproductive Medicine of the Dutch-speaking Brussels Free University, Belgium, which is a tertiary referral institution. PATIENTS:One hundred fifty-seven couples were enrolled in the study. Inclusion criteria allowed only first trials of couples with long-standing infertility caused by a male factor. Female factors were excluded. INTERVENTIONS:In ZIFT, up to three fertilized oocytes were transferred into one single patient fallopian tube by means of laparoscopy 18 hours after insemination. In IVF-ET, cleaving embryos were replaced into the uterine cavity about 48 hours after insemination. MAIN OUTCOME MEASURES:Fertilization and transfer rates, implantation and pregnancy rates, pregnancy outcome, and cost per procedure were evaluated. RESULTS:Implantation rates of 12.3% and 10% per replaced conceptus were achieved for ZIFT and IVF-ET, respectively. CONCLUSIONS:This study demonstrates no therapeutic advantage of ZIFT over IVF-ET in male-factor infertility in terms of reproductive outcome or economic benefit.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Tournaye H,Devroey P,Camus M,Valkenburg M,Bollen N,Van Steirteghem ACdoi
10.1016/s0015-0282(16)55195-4keywords:
subject
Has Abstractpub_date
1992-08-01 00:00:00pages
344-50issue
2eissn
0015-0282issn
1556-5653pii
S0015-0282(16)55195-4journal_volume
58pub_type
临床试验,杂志文章,随机对照试验abstract:OBJECTIVE(S):To investigate the pattern of follicular development in transplanted fetal and neonatal mouse ovaries in the presence or absence of the recipient's own ovaries. DESIGN:Controlled experiment. SETTING:Academic research laboratory, Department of Physiology, Monash University, Clayton, Australia. INTERVENTI...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(00)00635-x
更新日期:2000-08-01 00:00:00
abstract:OBJECTIVE:To describe the molecular, cytogenetic, immunohistochemical, and endocrinologic characteristics of a young 46,XY female with persistent müllerian structures and germ cell tumors in dysgenetic gonads. DESIGN:Descriptive case study. SETTING:Mackay Memorial Hospital and National Yang-Ming University, Taipei, T...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(99)00169-7
更新日期:1999-07-01 00:00:00
abstract::Testosterone and 19-nortestosterone derivatives were evaluated in a developmental scheme designed to identify competitive progesterone antagonists having abortifacient activity. Compounds that displayed significant binding to the rabbit uterine progesterone receptor were followed in biologic tests for progestational, ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)44003-3
更新日期:1979-05-01 00:00:00
abstract::Eighteen premenopausal women with symptomatic leiomyomata uteri were enrolled in a stratified, randomized, double-blind, placebo-controlled study evaluating the efficacy of leuprolide acetate (LA) depot treatment before myomectomy. Stratification was based on pretreatment uterine volume (less than 600 cm3 versus great...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1989-11-01 00:00:00
abstract::We found the prevalence of ovarian cancer in infertile women less than 40 years at the time of planned microsurgery for infertility to be 1 in 95. This may represent a greater prevalence of ovarian cancer than that of all women less than 40 years. Importantly, laparoscopy did not find the ovarian cancer in these women...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1988-03-01 00:00:00
abstract:OBJECTIVE:To discuss the new peer review system at the National Institutes of Health (NIH) and to present the process undertaken to accomplish these changes, with an emphasis on the reproductive sciences. DESIGN:A discussion of the many NIH committees and their composition and reports leading to the changes in peer re...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2003.10.006
更新日期:2004-02-01 00:00:00
abstract::Since the late 1980s premature progesterone elevation has repeatedly caught the attention of investigators, not only for its importance, but also because studies have shown differing results and conclusions, constituting an unexplainable sequence of doubts and uncertainties. This issue's Views and Reviews section seek...
journal_title:Fertility and sterility
pub_type:
doi:10.1016/j.fertnstert.2018.02.134
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:To report a case of a methotrexate (MTX)-resistant heterotopic interstitial pregnancy in which dactinomycin was necessary as a second-line chemotherapy. DESIGN:Case report. SETTING:Medical college-affiliated hospital. PATIENT(S):A 39-year-old woman with vaginal bleeding after the transfer of two thawed 8-c...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.10.003
更新日期:2009-03-01 00:00:00
abstract::Luteinization of an unruptured ovarian follicle has been reported as a cause of infertility and has heretofore been diagnosed only by direct visualization of the ovarian surface. Four patients who demonstrated defects in ovulation requiring therapy to induce ovulation and who were not achieving desired conception desp...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)46160-1
更新日期:1982-04-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy and side effects of vaginal misoprostol with dinoprostone for cervical priming before operative hysteroscopy and to assess the cervicouterine complications related to cervical dilatation and hysteroscopic surgery. DESIGN:A prospective randomized study. SETTING:Tertiary university hos...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2006.03.039
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:To evaluate whether DNA fragmentation and/or mitochondrial membrane potential (MMP) predict natural conception better than standard sperm parameters. DESIGN:Prospective cross-sectional study. SETTING:University medical center. PATIENT(S):Eighty-five infertile and 51 fertile men. INTERVENTION(S):Assessment...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2015.11.037
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:To examine the effects of different thermodynamic control systems on the temperature stability of human eggs during in vitro manipulation, with the integrity of meiotic spindles imaged using the LC-PolScope (Cambridge Research & Instrumentation, Inc., Woburn, MA). DESIGN:We performed intracytoplasmic sperm i...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(02)03117-5
更新日期:2002-06-01 00:00:00
abstract::One hundred and twenty rats were divided into six groups and laparotomized. In three of the groups the cecum was left intact. In one of these groups the cecum was only lifted up through the abdominal incision and then replaced in the abdominal cavity. In another group the intact cecum was bathed with a certain amount ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)43584-3
更新日期:1978-10-01 00:00:00
abstract::A new sperm isolation technique was studied in conjunction with the short-term freeze preservation of human spermatozoa. The isolation procedure yielded subpopulations of spermatozoa with very high percentage motility and progressive motility score, and which were virtually free of seminal debris. For 24 semen samples...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)42196-5
更新日期:1976-11-01 00:00:00
abstract:OBJECTIVE:To assess the effects of estro-progestin supplementation on ghrelin-mediated GH release, we studied the consequence of ghrelin or saline injection before and after 60 days of hormone therapy or placebo administration in postmenopausal subjects. DESIGN:A prospective double blind, placebo-controlled, and paral...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2007.02.042
更新日期:2008-02-01 00:00:00
abstract::A patient with primary adrenocortical deficiency presented with galactorrhea and hyperprolactinemia, in addition to the usual characteristic symptoms of adrenal insufficiency. With steroid replacement therapy, PRL levels returned to normal, with resumption of normal ovulatory cycles; and the patient became pregnant. P...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)48872-2
更新日期:1985-09-01 00:00:00
abstract:OBJECTIVE:To determine CA-125 levels in cervical mucus (CM) during the menstrual cycle and their relationship to gonadal steroids and ovulation. DESIGN:Prospective study. SETTING:Two academic tertiary referral centers. PARTICIPANTS:Thirteen women with a normal fertility work-up. INTERVENTIONS:CA-125 and protein con...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)56694-1
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVE:To investigate whether BRCA carriers with and without malignancy have decreased ovarian reserve at baseline compared with BRCA noncarriers. DESIGN:Retrospective cohort study. SETTING:Academic medical center. PATIENT(S):Seven-hundred and ninety-five oocyte cryopreservation patients, comprising BRCA carriers...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2018.10.014
更新日期:2019-02-01 00:00:00
abstract::An attempt was made to develop an interclass somatic cell nuclear transfer method as an alternative means of establishing chicken embryonic stem cells. Chicken-to-cattle interclass embryos that activated calcium ionophore, cycloheximide, and cytochalasin D were developed into blastocysts, and the developing interclass...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.06.019
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVE:To assess the effectiveness of a second laparoscopic ovarian diathermy (LOD) in women with polycystic ovary syndrome (PCOS). DESIGN:Retrospective study. SETTING:Tertiary infertility clinic. PATIENT(S):Twenty anovulatory infertile women with PCOS who underwent LOD 1-6 years previously. Twelve subjects had p...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(02)04960-9
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:To report a dichorionic quadramniotic quadruple gestation with monochorionic triamniotic triplets after intracytoplasmic sperm injection (ICSI) treatment and transfer of two embryos. DESIGN:Case report. SETTING:Academic reproductive medicine center. PATIENT(S):A 28-year-old nulligravida who underwent first...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.08.022
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVE:To compare pregnancy rates after fallopian tubal and uterine transfer of cryopreserved embryos. DESIGN:Prospective randomized trial with assignment to treatment groups by a random number table. SETTING:University of Iowa Hospitals and Clinics, a tertiary care academic institution. PATIENTS:Forty patients w...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0015-0282(16)57429-9
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVE:To compare the laparoscopic excision of primary versus recurrent ovarian endometriomas. DESIGN:Descriptive study. SETTING:Tertiary referral center for the treatment of endometriosis. PATIENT(S):Between 1993 and 2002, 359 consecutive patients: 305 primary surgeries (group A) and 54 reoperations for a recurr...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.08.028
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVE:To determine the expression of nitric oxide synthases (NOSs) and their modulation by hypoxia in human peritoneal (NF) and adhesion fibroblasts (ADF). DESIGN:Prospective experimental study. SETTING:University medical center. PATIENT(S):Fibroblasts from peritoneum and adhesion tissues. INTERVENTION(S):Hypox...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.07.1313
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To investigate whether ghrelin signaling is involved in the pathogenesis of male factor infertility induced by leptin deficiency. DESIGN:Experimental study. SETTING:University academic medical center. ANIMAL(S):Ten-week-old C57BL/6J mice and ob/ob mice. INTERVENTION(S):Western blotting, (quantitative) rev...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2012.11.022
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the impact of chronic GnRH antagonist therapy on the extent of GnRH agonist-induced gonadotrope desensitization. DESIGN:Prospective and controlled. SETTING:Primate Research Center. PARTICIPANTS:Six reproductive age cycling female baboons (Papio cyanocephalus anubis). INTERVENTIONS:The animals ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)57864-9
更新日期:1995-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the effects of laparoscopic bipolar coagulation of uterine vessels in treating symptomatic fibroids. DESIGN:Prospective clinical study. SETTING:University-affiliated tertiary referral center. PATIENT(S):Eighty-seven women with symptomatic fibroids warranting surgical treatment and wanting to re...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(00)01724-6
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:To evaluate FOXP3 polymorphisms (rs3761549, rs3761548, rs2232368, rs2232366, and rs2280883) in a group of infertile women with and without endometriosis and controls. DESIGN:Case control study. SETTING:Human Reproduction Outpatient Clinic of Faculdade de Medicina do ABC. PATIENT(S):The study groups were 17...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.03.033
更新日期:2011-06-01 00:00:00
abstract::This document is designed to assist in vitro fertility clinics in the management of cryopreserved reproductive tissues stored in cryogenic storage (cryostorage) tanks, based upon scientific principles and laboratory experience related to best practice for safe and reliable storage of cryopreserved reproductive tissue....
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2020.06.019
更新日期:2020-09-01 00:00:00
abstract::In overweight women with polycystic ovary syndrome, weight loss improves arterial compliance and postprandial lipidemia. Modifying dietary carbohydrate or protein in weight loss provided similar improvements in arterial compliance and postprandial lipidemia. ...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2010.02.057
更新日期:2010-11-01 00:00:00