Natriuretic peptides and echocardiography in acute dyspnoea: implication of elevated levels with normal systolic function.

abstract：AIMS:Brain natriuretic peptide (BNP), NT-proBNP and troponins are useful for the assessment of patients with heart failure. Few data exist about their serial changes and their prognostic value in patients with acute heart failure (AHF). METHODS AND RESULTS:NT-proBNP and troponin-T plasma levels were measured at baseli...

journal_title：European journal of heart failure

authors： Metra M,Nodari S,Parrinello G,Specchia C,Brentana L,Rocca P,Fracassi F,Bordonali T,Milani P,Danesi R,Verzura G,Chiari E,Dei Cas L

更新日期：2007-08-01 00:00:00

abstract：AIM:Mineralocorticoid receptor antagonists (MRAs) improve outcomes in heart failure with reduced ejection fraction (HFrEF), but are underutilized. Hyperkalaemia may be one reason, but the underlying reasons for underuse are unknown. The aim of this study was to investigate the independent predictors of MRA underuse in ...

journal_title：European journal of heart failure

authors： Savarese G,Carrero JJ,Pitt B,Anker SD,Rosano GMC,Dahlström U,Lund LH

更新日期：2018-09-01 00:00:00

abstract：AIMS:To investigate the relationship between central venous pressure (CVP) at presentation to the emergency room (ER) and the risk of cardiac rehospitalization and mortality in patients with decompensated heart failure (DHF). METHODS AND RESULTS:Central venous pressure was determined non-invasively using high-resoluti...

journal_title：European journal of heart failure

authors： Uthoff H,Thalhammer C,Potocki M,Reichlin T,Noveanu M,Aschwanden M,Staub D,Arenja N,Socrates T,Twerenbold R,Mutschmann-Sanchez S,Heinisch C,Jaeger KA,Mebazaa A,Mueller C

更新日期：2010-05-01 00:00:00

abstract：AIMS:The primary objective of this systematic review was to estimate the prevalence and temporal changes in chronic comorbid conditions reported in heart failure (HF) clinical trials. METHODS AND RESULTS:We searched MEDLINE for HF trials enrolling more than 400 patients published between 2001 and 2016.Trials were divi...

journal_title：European journal of heart failure

authors： Khan MS,Samman Tahhan A,Vaduganathan M,Greene SJ,Alrohaibani A,Anker SD,Vardeny O,Fonarow GC,Butler J

更新日期：2020-06-01 00:00:00

abstract：AIMS:As periprocedural risk is low, MitraClip implantation is often performed in critically ill, not fully recompensated patients, who are in NYHA functional class IV at the time of the procedure, to accelerate convalescence. We herein sought to evaluate the procedural and 30-day outcome of this patient group. METHODS...

journal_title：European journal of heart failure

authors： Rudolph V,Huntgeburth M,von Bardeleben RS,Boekstegers P,Lubos E,Schillinger W,Ouarrak T,Eggebrecht H,Butter C,Plicht B,May A,Franzen O,Schofer J,Senges J,Baldus S

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Oxygen (O2) uptake at peak exercise (VO2 peak) is an objective measurement of functional capacity in patients with chronic heart failure (CHF). The significance of recovery O2 kinetics parameters in predicting exercise capacity, and the parameters of submaximal exercise testing have not been thoroughly exami...

journal_title：European journal of heart failure

authors： Nanas S,Nanas J,Kassiotis C,Nikolaou C,Tsagalou E,Sakellariou D,Terovitis I,Papazachou O,Drakos S,Papamichalopoulos A,Roussos C

更新日期：2001-12-01 00:00:00

abstract：AIMS:In the Digitalis Investigation Group (DIG) trial, digoxin reduced mortality or hospitalization due to heart failure (HF) in several pre-specified high-risk subgroups of HF patients, but data on protocol-specified 2-year outcomes were not presented. In the current study, we examined the effect of digoxin on HF deat...

journal_title：European journal of heart failure

authors： Gheorghiade M,Patel K,Filippatos G,Anker SD,van Veldhuisen DJ,Cleland JG,Metra M,Aban IB,Greene SJ,Adams KF,McMurray JJ,Ahmed A

更新日期：2013-05-01 00:00:00

abstract：AIMS:To determine the association between obesity and outcomes in post-acute myocardial infarction (AMI) patients with systolic heart failure (HF). METHODS AND RESULTS:Of the 6632 Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS) participants, 6611 had data on baseline bod...

journal_title：European journal of heart failure

authors： Wu AH,Pitt B,Anker SD,Vincent J,Mujib M,Ahmed A

更新日期：2010-06-01 00:00:00

abstract：:Carvedilol has been shown to be beneficial for patients with heart failure, but it is not clear how it should be initiated in routine clinical practice, particularly in the elderly. This study is a retrospective review of 19 patients of age 80+/-4 years with heart failure, who had Carvedilol treatment initiated in a r...

journal_title：European journal of heart failure

authors： Owen A

更新日期：2000-09-01 00:00:00

abstract：:Alternations in gut microbial composition (i.e. loss of microbial diversity or 'gut dysbiosis') have been associated with heart failure with reduced ejection fraction (HFrEF). It has also been suggested that increased chronic low-level inflammation and immune system dysregulation seen in patients with HFrEF could be r...

journal_title：European journal of heart failure

authors： Madan S,Mehra MR

更新日期：2020-04-01 00:00:00

abstract：AIMS:Chronic hypertension may cause left ventricular hypertrophy (LVH). The role of matrix metalloproteinases (MMPs), tissue inhibitors of matrix metalloproteinases (TIMPs), and tenascin-C (Tn-C) splice variants in concentric vs. eccentric left ventricular remodelling has not been investigated. METHODS AND RESULTS:Ser...

journal_title：European journal of heart failure

authors： Franz M,Berndt A,Altendorf-Hofmann A,Fiedler N,Richter P,Schumm J,Fritzenwanger M,Figulla HR,Brehm BR

更新日期：2009-11-01 00:00:00

abstract：AIMS:Ventricular septal rupture (VSR) became a rare mechanical complication of myocardial infarction in the era of percutaneous coronary interventions but is associated with extreme mortality in patients who present with cardiogenic shock (CS). Promising outcomes have been reported with the use of circulatory support a...

journal_title：European journal of heart failure

authors： Rob D,Špunda R,Lindner J,Rohn V,Kunstýř J,Balík M,Rulíšek J,Kopecký P,Lipš M,Šmíd O,Kovárník T,Mlejnský F,Linhart A,Bělohlávek J

更新日期：2017-05-01 00:00:00

abstract：AIMS:Undetected atrial fibrillation (AF) may be common in the heart failure with preserved ejection fraction (HFpEF) population, and failure to detect this may lead to the missing of opportunities to prevent associated subclinical cerebral infarctions (SCIs) and cognitive decline. METHODS AND RESULTS:We studied 1527 p...

journal_title：European journal of heart failure

authors： Cogswell RJ,Norby FL,Gottesman RF,Chen LY,Solomon S,Shah A,Alonso A

更新日期：2017-10-01 00:00:00

abstract：AIMS:The cardio-renal syndrome plays a critical role in acute heart failure (HF). Levosimendan, an inodilator drug, has a positive but controversial effect on kidney. Our aim was to evaluate its effects on both renal and systemic haemodynamic parameters as well as on renal function, explaining the possible mechanisms i...

journal_title：European journal of heart failure

authors： Fedele F,Bruno N,Brasolin B,Caira C,D'Ambrosi A,Mancone M

更新日期：2014-03-01 00:00:00

abstract：:Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are global epidemics incurring significant morbidity and mortality. The combination presents many diagnostic challenges. Clinical symptoms and signs frequently overlap. Evaluation of cardiac and pulmonary function is often problematic and occasionally...

journal_title：European journal of heart failure

authors： Hawkins NM,Petrie MC,Jhund PS,Chalmers GW,Dunn FG,McMurray JJ

更新日期：2009-02-01 00:00:00

abstract：AIMS:Recent studies have shown that microRNAs (miRNAs), besides being potent regulators of gene expression, can additionally serve as circulating biomarkers of disease. The aim of this study is to determine if plasma miRNAs can be used as indicators of disease progression or therapeutic efficacy in hypertension-induced...

journal_title：European journal of heart failure

authors： Dickinson BA,Semus HM,Montgomery RL,Stack C,Latimer PA,Lewton SM,Lynch JM,Hullinger TG,Seto AG,van Rooij E

更新日期：2013-06-01 00:00:00

abstract：AIMS:To compare the effects of lipophilic simvastatin and hydrophilic rosuvastatin on plasma adiponectin and glycated haemoglobin A1c (HbA1c) levels in patients with non-ischaemic chronic heart failure (NICHF). METHODS AND RESULTS:Seventy-one stable outpatients with NICHF, who were already receiving standard therapy f...

journal_title：European journal of heart failure

authors： Tsutamoto T,Yamaji M,Kawahara C,Nishiyama K,Fujii M,Yamamoto T,Horie M

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Plasma renin activity is normal in left ventricular dysfunction in the absence of diuretic therapy. In health there is a reciprocal relationship between renin and atrial natriuretic peptide (ANP) but a positive correlation in advanced heart failure. The relationship between renin and ANP in mild left ventric...

journal_title：European journal of heart failure

authors： Dutka DP,Puri S,Strong R,Cleland JG

更新日期：1999-12-01 00:00:00

abstract：:We have documented a pre-junctional beta-2 adrenoceptor mediated reduction in cardiac norepinephrine spillover (CNES) in heart failure patients receiving chronic beta-blockade. Our present objective was to ascertain the consequence of this decrease for vagal heart rate (HR) regulation by determining CNES, arterial bar...

journal_title：European journal of heart failure

authors： Kubo T,Parker JD,Azevedo ER,Atchison DJ,Newton GE,Picton P,Floras JS

更新日期：2005-08-01 00:00:00

abstract：:The European Society of Cardiology heart failure guidelines firmly recommend regular physical activity and structured exercise training (ET), but this recommendation is still poorly implemented in daily clinical practice outside specialized centres and in the real world of heart failure clinics. In reality, exercise i...

journal_title：European journal of heart failure

authors： Piepoli MF,Conraads V,Corrà U,Dickstein K,Francis DP,Jaarsma T,McMurray J,Pieske B,Piotrowicz E,Schmid JP,Anker SD,Solal AC,Filippatos GS,Hoes AW,Gielen S,Giannuzzi P,Ponikowski PP

更新日期：2011-04-01 00:00:00

abstract：AIMS:Latent heart failure at rest can be observed in a number of patients upon exercise. Considering left atrial (LA) remodelling as the reflection of the cumulative effects of the LV filling pressure (FP) over time, our aim was to investigate whether the LA volume would predict abnormal exercise LVFP. METHODS AND RES...

journal_title：European journal of heart failure

authors： Hammoudi N,Achkar M,Laveau F,Boubrit L,Djebbar M,Allali Y,Komajda M,Isnard R

更新日期：2014-10-01 00:00:00

abstract：AIMS:Over the last 30 years, many medicine development programmes in acute and chronic heart failure (HF) with preserved ejection fraction (HFpEF) have failed, in contrast to those in HF with reduced ejection fraction (HFrEF). We explore how the neutral results in larger HF trials may be attributable to chance and/or t...

journal_title：European journal of heart failure

authors： Davison BA,Takagi K,Senger S,Koch G,Metra M,Kimmoun A,Mebazaa A,Voors AA,Nielsen OW,Chioncel O,Pang PS,Greenberg BH,Maggioni AP,Cohen-Solal A,Ertl G,Sato N,Teerlink JR,Filippatos G,Ponikowski P,Gayat E,Edwards C,

更新日期：2020-09-01 00:00:00

abstract：:It is well known that atrial fibrillation can lead to heart failure, and is attributed to rapid ventricular rate (tachycardia-induced cardiomyopathy). Some recent studies suggest the possible existence of an intrinsic left-ventricular factor related to atrial fibrillation, irrespective of other elements. In order to d...

journal_title：European journal of heart failure

authors： Jourdain P,Bellorini M,Funck F,Fulla Y,Guillard N,Loiret J,Thebault B,Sadeg N,Desnos M

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Acute dyspnoea as a presenting symptom is a frequent diagnostic challenge for physicians. The main differential diagnosis is between dyspnoea of cardiac and non-cardiac origin. Natriuretic peptides have been shown to be useful in this setting. Ultrasound lung comets (ULCs) are a simple, echographic method wh...

journal_title：European journal of heart failure

authors： Gargani L,Frassi F,Soldati G,Tesorio P,Gheorghiade M,Picano E

更新日期：2008-01-01 00:00:00

abstract：AIMS:To investigate the prevalence of iron deficiency (ID) in heart failure (HF) patients with normal vs. abnormal red cell indices (RCI), the associations between iron parameters and RCI, and prognostic consequences of ID independently of RCI. METHODS AND RESULTS:We analysed clinical data of 1821 patients with HF [me...

journal_title：European journal of heart failure

authors： Tkaczyszyn M,Comín-Colet J,Voors AA,van Veldhuisen DJ,Enjuanes C,Moliner-Borja P,Rozentryt P,Poloński L,Banasiak W,Ponikowski P,van der Meer P,Jankowska EA

更新日期：2018-01-01 00:00:00

abstract：AIMS:Liver X receptors (LXRs) transcriptionally regulate inflammation, metabolism, and immunity. Synthetic LXR agonists have been evaluated for their efficacy in the cardiovascular system; however, they elicit prolipogenic side effects which substantially limit their therapeutic use. AZ876 is a novel high-affinity LXR ...

journal_title：European journal of heart failure

authors： Cannon MV,Yu H,Candido WM,Dokter MM,Lindstedt EL,Silljé HH,van Gilst WH,de Boer RA

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:High-sensitivity C-reactive protein (CRP) is an inflammatory marker that predicts coronary heart disease (CHD) and, in recent studies, incident heart failure (HF). Whether the association of inflammation with incident HF is explained by worse baseline left ventricular dysfunction or by underlying CHD is unkn...

journal_title：European journal of heart failure

authors： Williams ES,Shah SJ,Ali S,Na BY,Schiller NB,Whooley MA

更新日期：2008-01-01 00:00:00

abstract：:Cardiac resynchronization therapy (CRT) is one of the most effective therapies for heart failure with reduced ejection fraction and leads to improved quality of life, reductions in heart failure hospitalization rates and reduces all-cause mortality. Nevertheless, up to two-thirds of eligible patients are not referred ...

journal_title：European journal of heart failure

authors： Mullens W,Auricchio A,Martens P,Witte K,Cowie MR,Delgado V,Dickstein K,Linde C,Vernooy K,Leyva F,Bauersachs J,Israel CW,Lund L,Donal E,Boriani G,Jaarsma T,Berruezo A,Traykov V,Yousef Z,Kalarus Z,Nielsen JC,Steff

更新日期：2020-11-02 00:00:00

abstract：AIMS:Neutrophil gelatinase-associated lipocalin (NGAL) is a measure of acute kidney injury. Renal dysfunction portends significant risk after discharge from acute heart failure (AHF). Thus, a sensitive marker of renal injury might also help to risk stratify HF patients. METHODS AND RESULTS:GALLANT [NGAL EvaLuation Alo...

journal_title：European journal of heart failure

authors： Maisel AS,Mueller C,Fitzgerald R,Brikhan R,Hiestand BC,Iqbal N,Clopton P,van Veldhuisen DJ

更新日期：2011-08-01 00:00:00

abstract：:Transthyretin amyloidosis (ATTR) is a rare, yet underdiagnosed disease characterized by progressive impairment of neurologic and cardiac function due to deposition of misfolded transthyretin. Despite great efforts, such as the introduction of orthotopic liver transplant, the devastating prognosis for both variant and ...

journal_title：European journal of heart failure

authors： Müller ML,Butler J,Heidecker B

更新日期：2020-01-01 00:00:00