The role of plasma biomarkers in acute heart failure. Serial changes and independent prognostic value of NT-proBNP and cardiac troponin-T.

abstract：AIMS:Despite improvement in prognosis for ST-elevation myocardial infarction (STEMI) patients, mortality remains high in STEMI patients presenting with cardiogenic shock (CS). Right ventricular (RV) dysfunction is an established independent predictor for adverse prognosis in STEMI patients without CS. The purpose of ou...

journal_title：European journal of heart failure

authors： Engström AE,Vis MM,Bouma BJ,van den Brink RB,Baan J Jr,Claessen BE,Kikkert WJ,Sjauw KD,Meuwissen M,Koch KT,de Winter RJ,Tijssen JG,Piek JJ,Henriques JP

更新日期：2010-03-01 00:00:00

abstract：:We investigated the hypothesis that increased intracellular [Na+]i in heart failure contributes to preservation of SR Ca2+ load which may become particularly evident at slow heart rates. [Na+]i in SBFI-loaded myocytes from rabbits with pacing-induced heart failure (PHF) was significantly higher at each frequency as co...

journal_title：European journal of heart failure

authors： Schillinger W,Teucher N,Christians C,Kohlhaas M,Sossalla S,Van Nguyen P,Schmidt AG,Schunck O,Nebendahl K,Maier LS,Zeitz O,Hasenfuss G

更新日期：2006-11-01 00:00:00

abstract：:The incidence and prevalence of cardiovascular disease increases progressively with advancing age. Cardiovascular disease is a major cause of morbidity and mortality in Western Countries. In the near future, as the population ages, it is expected that the population prevalence of cardiovascular disease will increase d...

journal_title：European journal of heart failure

authors： Wong LS,de Boer RA,Samani NJ,van Veldhuisen DJ,van der Harst P

更新日期：2008-11-01 00:00:00

abstract：AIMS:Several studies have shown that older patients with heart failure with reduced ejection fraction (HFrEF) are undertreated. The aim of this study was to evaluate the association of up-titration of angiotensin-converting enzyme inhibitors (ACEI), angiotensin receptor blockers (ARB) and beta-blockers on outcome acros...

journal_title：European journal of heart failure

authors： Mordi IR,Ouwerkerk W,Anker SD,Cleland JG,Dickstein K,Metra M,Ng LL,Samani NJ,van Veldhuisen DJ,Zannad F,Voors AA,Lang CC

更新日期：2020-03-25 00:00:00

abstract：BACKGROUND:Plasma renin activity is normal in left ventricular dysfunction in the absence of diuretic therapy. In health there is a reciprocal relationship between renin and atrial natriuretic peptide (ANP) but a positive correlation in advanced heart failure. The relationship between renin and ANP in mild left ventric...

journal_title：European journal of heart failure

authors： Dutka DP,Puri S,Strong R,Cleland JG

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Approximately one third of patients with chronic heart failure have left bundle branch block (LBBB) on their 12-lead ECG. METHODS AND RESULTS:1418 consecutive patients (average (SD) age 70.5 (10.4) years; 74% male) first seen in a community heart failure clinic between December 2001 and June 2006 had a 12 l...

journal_title：European journal of heart failure

authors： Clark AL,Goode K,Cleland JG

更新日期：2008-07-01 00:00:00

abstract：AIMS:Heart failure (HF) quality registries report quality of care but it is unknown whether they improve outcomes. The aims were to assess predictors of enrolment in a HF registry, test the hypothesis that enrolment in a HF registry is associated with reduced mortality, and assess potential explanatory factors for this...

journal_title：European journal of heart failure

authors： Lund LH,Carrero JJ,Farahmand B,Henriksson KM,Jonsson Å,Jernberg T,Dahlström U

更新日期：2017-09-01 00:00:00

abstract：AIMS:Women with heart failure (HF) are under-represented in individual randomized clinical trials (RCTs). Little is known about sex-specific treatment effects in HF medications. We evaluated sex differences in the response to mineralocorticoid receptor antagonists (MRAs) in major HF MRA trials, including a broad spectr...

journal_title：European journal of heart failure

authors： Rossello X,Ferreira JP,Pocock SJ,McMurray JJV,Solomon SD,Lam CSP,Girerd N,Pitt B,Rossignol P,Zannad F

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:EMPEROR-Preserved is an ongoing trial evaluating the effect of empagliflozin in patients with heart failure with preserved ejection fraction (HFpEF). This report describes the baseline characteristics of the EMPEROR-Preserved cohort and compares it with patients enrolled in prior HFpEF trials. METHODS:EMPER...

journal_title：European journal of heart failure

authors： Anker SD,Butler J,Filippatos G,Khan MS,Ferreira JP,Bocchi E,Böhm M,Rocca HPB,Choi DJ,Chopra V,Chuquiure E,Giannetti N,Gomez-Mesa JE,Janssens S,Januzzi JL,Gonzalez-Juanatey JR,Merkely B,Nicholls SJ,Perrone SV,Piña IL

更新日期：2020-11-29 00:00:00

abstract：:Heart failure (HF) in elderly patients is associated with more diffuse symptoms and signs due to the presence of other noncardiac comorbidities. This can cause difficulties in assessing the correct diagnosis and initiating appropriate therapy. The four most frequently occurring noncardiac comorbidities and therapies u...

journal_title：European journal of heart failure

authors： Dahlström U

更新日期：2005-03-16 00:00:00

abstract：AIMS:Endothelial dysfunction has been shown to correlate with severity of congestive heart failure (CHF) and recent data suggest morphological changes of peripheral vasculature to be associated with the syndrome. We therefore investigated the hypothesis that vascular remodeling is associated with functional changes in ...

journal_title：European journal of heart failure

authors： Poelzl G,Frick M,Huegel H,Lackner B,Alber HF,Mair J,Herold M,Schwarzacher S,Pachinger O,Weidinger F

更新日期：2005-01-01 00:00:00

abstract：AIMS:The goal of the study was to examine the prognostic impact, haemodynamic and clinical features associated with lung congestion in patients with chronic heart failure (HF). METHODS AND RESULTS:HF patients (n = 186) and HF-free controls (n = 21) underwent right heart catheterization, echocardiography, pulmonary fun...

journal_title：European journal of heart failure

authors： Melenovsky V,Andersen MJ,Andress K,Reddy YN,Borlaug BA

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Long-term prognosis of coronary artery disease (CAD) patients is worsened when stress ischemia persists on treatment, but the relationship with adverse cardiac remodelling had never been investigated. AIM:To analyze changes in blood markers of fibrosis in patients with chronic CAD exhibiting exercise ischae...

journal_title：European journal of heart failure

authors： Radauceanu A,Moulin F,Djaballah W,Marie PY,Alla F,Dousset B,Virion JM,Capiaumont J,Karcher G,Aliot E,Zannad F

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Suppression of the renin-angiotensin-aldosterone system (RAAS) is therapeutically valuable in chronic heart failure (CHF). RAAS inhibition can be achieved in a number of ways though an orally active renin inhibitor (RI) has never been studied before. We describe the neurohumoral effects of an RI. METHODS AN...

journal_title：European journal of heart failure

authors： Seed A,Gardner R,McMurray J,Hillier C,Murdoch D,MacFadyen R,Bobillier A,Mann J,McDonagh T

更新日期：2007-11-01 00:00:00

abstract：:Dilated cardiomyopathy (DCM) represents a particular aetiology of systolic heart failure that frequently has a genetic background and usually affects young patients with few co-morbidities. The prognosis of DCM has improved substantially during the last decades due to more accurate aetiological characterization, the r...

journal_title：European journal of heart failure

authors： Merlo M,Cannatà A,Gobbo M,Stolfo D,Elliott PM,Sinagra G

更新日期：2018-02-01 00:00:00

abstract：AIMS:Red cell distribution width (RDW) has been associated with cardiovascular disease, but the relation to heart failure (HF) is unclear. We investigated the association between RDW and incidence of first hospitalization due to HF in a population-based cohort. METHODS AND RESULTS:Red cell distribution width was measu...

journal_title：European journal of heart failure

authors： Borné Y,Smith JG,Melander O,Hedblad B,Engström G

更新日期：2011-12-01 00:00:00

abstract：AIMS:Non-invasive measures of cardiac mechanical function may have the potential to serve as markers of risk for heart failure; however, limited data exist regarding clinical correlates and heritability of these measures in the community. METHODS AND RESULTS:We used speckle-tracking echocardiography to assess LV strai...

journal_title：European journal of heart failure

authors： Cheng S,McCabe EL,Larson MG,Chen MH,Osypiuk E,Lehman BT,Stantchev P,Aragam J,Solomon SD,Benjamin EJ,Vasan RS

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Chronic heart failure (CHF) is common and is frequently managed by primary care physicians (PCPs). Despite the European Society of Cardiology (ESC) Guidelines, standard treatments for CHF are frequently underutilised, particularly in primary care. AIM:To evaluate current drug therapy for CHF in adults with ...

journal_title：European journal of heart failure

authors： Ceia F,Fonseca C,Mota T,Morais H,Matias F,Costa C,Oliveira AG

更新日期：2004-10-01 00:00:00

abstract：AIMS:It is unclear whether myocardial velocity or deformation indices of dyssynchrony are better at predicting response to cardiac resynchronization therapy (CRT). Therefore, two indices of left ventricular (LV) dyssynchrony based on myocardial velocity and deformation were compared to predict success of CRT. METHODS ...

journal_title：European journal of heart failure

authors： Mele D,Toselli T,Capasso F,Stabile G,Piacenti M,Piepoli M,Giatti S,Klersy C,Sallusti L,Ferrari R

更新日期：2009-04-01 00:00:00

abstract：AIMS:To compare the effects of lipophilic simvastatin and hydrophilic rosuvastatin on plasma adiponectin and glycated haemoglobin A1c (HbA1c) levels in patients with non-ischaemic chronic heart failure (NICHF). METHODS AND RESULTS:Seventy-one stable outpatients with NICHF, who were already receiving standard therapy f...

journal_title：European journal of heart failure

authors： Tsutamoto T,Yamaji M,Kawahara C,Nishiyama K,Fujii M,Yamamoto T,Horie M

更新日期：2009-12-01 00:00:00

abstract：AIMS:Myostatin inhibits myoblast differentiation/proliferation and may play a role in heart failure (HF) and reverse remodelling after left ventricular assist device (LVAD) support. This study sought to characterize myostatin expression and activation in advanced HF before and after LVAD support. METHODS AND RESULTS:L...

journal_title：European journal of heart failure

authors： George I,Bish LT,Kamalakkannan G,Petrilli CM,Oz MC,Naka Y,Sweeney HL,Maybaum S

更新日期：2010-05-01 00:00:00

abstract：:Heart failure and sleep apnoea are major health problems with an increasingly recognized association; evidence suggests that sleep apnoea may play a role in the progression of heart failure. However, confounding factors such as obesity, hypertension and coronary heart disease make this relationship uncertain and an in...

journal_title：European journal of heart failure

authors： Ferreira S,Winck J,Bettencourt P,Rocha-Goncalves F

更新日期：2006-05-01 00:00:00

abstract：AIMS:In the Digitalis Investigation Group (DIG) trial, digoxin reduced mortality or hospitalization due to heart failure (HF) in several pre-specified high-risk subgroups of HF patients, but data on protocol-specified 2-year outcomes were not presented. In the current study, we examined the effect of digoxin on HF deat...

journal_title：European journal of heart failure

authors： Gheorghiade M,Patel K,Filippatos G,Anker SD,van Veldhuisen DJ,Cleland JG,Metra M,Aban IB,Greene SJ,Adams KF,McMurray JJ,Ahmed A

更新日期：2013-05-01 00:00:00

abstract：AIMS:To determine whether a strategy of intensive blood pressure control reduces the risk of heart failure (HF) events consistently across the spectrum of kidney function and albuminuria. METHODS AND RESULTS:SPRINT was a randomized clinical trial in which 9361 individuals ≥50 years, at high risk for or with cardiovasc...

journal_title：European journal of heart failure

authors： Vaduganathan M,Pareek M,Kristensen AMD,Biering-Sørensen T,Byrne C,Almarzooq Z,Olesen TB,Olsen MH,Bhatt DL

更新日期：2020-07-21 00:00:00

abstract：BACKGROUND:Plasma concentrations of atrial natriuretic peptides are correlated with atrial pressures, as are left ventricular ejection fraction and left ventricular filling abnormalities. AIMS:This study investigated the relation of atrial natriuretic peptides to both left ventricular systolic and diastolic function i...

journal_title：European journal of heart failure

authors： Wijbenga AA,Balk AH,Jonkman FA,Boomsma F,Simoons ML,Man in t Veld AJ

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Information about the occurrence of heart failure in the acute phase of myocardial infarction (MI) in diabetic patients and its impact on prognosis are sparse. AIM:The purpose of the present study was to describe how MI patients with diabetes mellitus (DM) differed from MI patients without DM with respect t...

journal_title：European journal of heart failure

authors： Melchior T,Rask-Madsen C,Torp-Pedersen C,Hildebrandt P,Køber L,Jensen G

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:To compare the efficacy of the homeopathic Crataegus preparation Cralonin for non-inferiority to standard treatment for mild cardiac insufficiency. METHODS:Multicentre non-randomised cohort study in patients aged 50-75 years in New York Heart Association class II. Patients received Cralonin (n=110) or ACE i...

journal_title：European journal of heart failure

authors： Schröder D,Weiser M,Klein P

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Ultrastructural findings of idiopathic dilated cardiomyopathy (IDCM) include myocyte atrophy and myofilament loss, yet little is known about the vascular abnormalities present in IDCM. METHODS AND RESULTS:Patients with IDCM and controls underwent multi-slice CT to examine length and diameter of epicardial v...

journal_title：European journal of heart failure

authors： Roura S,Planas F,Prat-Vidal C,Leta R,Soler-Botija C,Carreras F,Llach A,Hove-Madsen L,Pons Lladó G,Farré J,Cinca J,Bayes-Genis A

更新日期：2007-10-01 00:00:00

abstract：:Impaired cardiac function is frequently accompanied by peripheral vascular dysfunction and a pro-inflammatory condition, which may be associated with elevated levels of angiotensin II. We hypothesized that the magnitude of flow mediated dilatation (FMD) of the brachial artery of post myocardial infarction patients wil...

journal_title：European journal of heart failure

authors： Kovacs I,Toth J,Tarjan J,Koller A

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Bifocal pacing (BFP) has been proposed as a feasible alternative to cardiac resynchronization therapy. AIM:To evaluate BFP in patients with severe heart failure and significant intraventricular conduction delay and to compare it with biventricular pacing (BVP). METHODS:Echocardiographic examination includi...

journal_title：European journal of heart failure

authors： Bulava A,Lukl J

更新日期：2007-03-01 00:00:00