Telomere biology in heart failure.

abstract：AIMS:Left ventricular contractile reserve is a prognostic indicator for adverse outcome in patients with severe chronic heart failure with reduced ejection fraction (HFrEF). We investigated the dobutamine-induced changes of LV multidimensional deformation and their predictive value for cardiac mortality of patients wit...

journal_title：European journal of heart failure

authors： Paraskevaidis IA,Ikonomidis I,Simitsis P,Parissis J,Stasinos V,Makavos G,Lekakis J

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Most patients suspected of having heart failure (HF) will get a 12-lead electrocardiogram (ECG) but its utility for excluding HF or assisting in its management has rarely been investigated. METHODS:The EuroHeart Failure survey identified 11,327 patients hospitalised with a suspected diagnosis of HF from 115...

journal_title：European journal of heart failure

authors： Khan NK,Goode KM,Cleland JG,Rigby AS,Freemantle N,Eastaugh J,Clark AL,de Silva R,Calvert MJ,Swedberg K,Komajda M,Mareev V,Follath F,EuroHeart Failure Survey Investigators.

更新日期：2007-05-01 00:00:00

abstract：:Despite the availability of a number of different classes of therapeutic agents with proven efficacy in heart failure, the clinical course of heart failure patients is characterized by a reduction in life expectancy, a progressive decline in health-related quality of life and functional status, as well as a high risk ...

journal_title：European journal of heart failure

authors： Cowie MR,Filippatos GS,Alonso Garcia MLA,Anker SD,Baczynska A,Bloomfield DM,Borentain M,Bruins Slot K,Cronin M,Doevendans PA,El-Gazayerly A,Gimpelewicz C,Honarpour N,Janmohamed S,Janssen H,Kim AM,Lautsch D,Laws I,Lefk

更新日期：2017-06-01 00:00:00

abstract：AIMS:To determine whether a strategy of intensive blood pressure control reduces the risk of heart failure (HF) events consistently across the spectrum of kidney function and albuminuria. METHODS AND RESULTS:SPRINT was a randomized clinical trial in which 9361 individuals ≥50 years, at high risk for or with cardiovasc...

journal_title：European journal of heart failure

authors： Vaduganathan M,Pareek M,Kristensen AMD,Biering-Sørensen T,Byrne C,Almarzooq Z,Olesen TB,Olsen MH,Bhatt DL

更新日期：2020-07-21 00:00:00

abstract：OBJECTIVE:To evaluate the utility of NT-proBNP in the emergency diagnosis and in-hospital monitoring of patients with acute dyspnoea and ventricular dysfunction. BACKGROUND:Misdiagnosis of heart failure (HF) is common in the urgent care setting using clinical diagnostic tests. Reports show that BNP is useful to diagno...

journal_title：European journal of heart failure

authors： Bayés-Genís A,Santaló-Bel M,Zapico-Muñiz E,López L,Cotes C,Bellido J,Leta R,Casan P,Ordóñez-Llanos J

更新日期：2004-03-15 00:00:00

abstract：BACKGROUND:Carvedilol improves left ventricular (LV) function when heart failure is due to LV systolic dysfunction, but the magnitude of the response is heterogeneous among patients with coronary disease, possibly reflecting the presence or volume of hibernating myocardium. AIMS:The primary objective of the study is t...

journal_title：European journal of heart failure

authors： Cleland JG,Pennel D,Ray S,Murray G,MacFarlane P,Cowley A,Coats A,Lahiri A

更新日期：1999-06-01 00:00:00

abstract：AIMS:Quantification of linear lung ultrasound (LUS) artefacts (B-lines) represents a novel, non-invasive approach to assess pulmonary congestion. We investigated the relationship between the number of B-lines (vertical artefacts arising from the pleural line) and intracardiac pressures. METHODS AND RESULTS:Prior to sc...

journal_title：European journal of heart failure

authors： Platz E,Lattanzi A,Agbo C,Takeuchi M,Resnic FS,Solomon SD,Desai AS

更新日期：2012-11-01 00:00:00

abstract：:Ventricular assist device implantation has become an established therapy in adults and children for bridging to heart transplantation or to aid myocardial recovery. Recently, implantation of left ventricular assist devices as definitive therapy has been recognized as a better option than pharmacological treatment in p...

journal_title：European journal of heart failure

authors： Potapov EV,Jurmann MJ,Drews T,Pasic M,Loebe M,Weng Y,Hetzer R

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Coronary artery disease (CAD) is frequent among patients hospitalized with acute heart failure syndromes (AHFS). AIMS:To describe the influence of coronary revascularization status on survival in patients with AHFS. METHODS AND RESULTS:OPTIMIZE-HF enrolled 48,612 patients with AHFS from 259 U.S. hospitals....

journal_title：European journal of heart failure

authors： Rossi JS,Flaherty JD,Fonarow GC,Nunez E,Gattis Stough W,Abraham WT,Albert NM,Greenberg BH,O'Connor CM,Yancy CW,Young JB,Davidson CJ,Gheorghiade M

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that discharge planning and post-discharge support for CHF patients can contribute greatly to the medical management of heart failure (CHF) in the community and that the quality of the CHF patient's close personal relationships can influence outcome in CHF. However, there has bee...

journal_title：European journal of heart failure

authors： Molloy GJ,Johnston DW,Witham MD

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:In patients with heart failure and reduced left ventricular ejection fraction, angiotensin receptor blockers have been found to reduce mortality and morbidity and to prevent or reverse left ventricular remodelling, compared to optimized background treatment. In light of these data, The Heart failure Endpoint...

journal_title：European journal of heart failure

authors： Konstam MA,Poole-Wilson PA,Dickstein K,Drexler H,Justice SJ,Komajda M,Malbecq W,Martinez FA,Neaton JD,Riegger GA,Guptha S

更新日期：2008-09-01 00:00:00

abstract：INTRODUCTION:Patients with chronic heart failure (CHF) experience breathlessness and fatigue on exercise. One of the abnormalities seen on maximal exercise testing is an increased ventilatory response to exercise (VE/VCO(2) slope). The cause of this is unknown, but is likely to be due to a combination of interacting pe...

journal_title：European journal of heart failure

authors： Witte KK,Clark AL

更新日期：2004-10-01 00:00:00

abstract：AIMS:Liver X receptors (LXRs) transcriptionally regulate inflammation, metabolism, and immunity. Synthetic LXR agonists have been evaluated for their efficacy in the cardiovascular system; however, they elicit prolipogenic side effects which substantially limit their therapeutic use. AZ876 is a novel high-affinity LXR ...

journal_title：European journal of heart failure

authors： Cannon MV,Yu H,Candido WM,Dokter MM,Lindstedt EL,Silljé HH,van Gilst WH,de Boer RA

更新日期：2015-03-01 00:00:00

abstract：AIMS:To determine the association between obesity and outcomes in post-acute myocardial infarction (AMI) patients with systolic heart failure (HF). METHODS AND RESULTS:Of the 6632 Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS) participants, 6611 had data on baseline bod...

journal_title：European journal of heart failure

authors： Wu AH,Pitt B,Anker SD,Vincent J,Mujib M,Ahmed A

更新日期：2010-06-01 00:00:00

abstract：AIMS:Myostatin inhibits myoblast differentiation/proliferation and may play a role in heart failure (HF) and reverse remodelling after left ventricular assist device (LVAD) support. This study sought to characterize myostatin expression and activation in advanced HF before and after LVAD support. METHODS AND RESULTS:L...

journal_title：European journal of heart failure

authors： George I,Bish LT,Kamalakkannan G,Petrilli CM,Oz MC,Naka Y,Sweeney HL,Maybaum S

更新日期：2010-05-01 00:00:00

abstract：AIMS:Women are more likely to develop heart failure with preserved ejection fraction (HFpEF) than men. We studied the relationship between sex and cardiovascular structure and function in patients with HFpEF. METHODS AND RESULTS:The study included 279 participants from the PARAMOUNT study (57% women) with analysable b...

journal_title：European journal of heart failure

authors： Gori M,Lam CS,Gupta DK,Santos AB,Cheng S,Shah AM,Claggett B,Zile MR,Kraigher-Krainer E,Pieske B,Voors AA,Packer M,Bransford T,Lefkowitz M,McMurray JJ,Solomon SD,PARAMOUNT Investigators.

更新日期：2014-05-01 00:00:00

abstract：:Ambulatory blood pressure monitoring has established its use in the definition of white coat hypertension and monitoring of treatment of essential hypertension. Any role for ambulatory blood pressure monitoring in heart failure is not well defined. However, from the limited studies available, ambulatory blood pressure...

journal_title：European journal of heart failure

authors： Goyal D,Macfadyen RJ,Watson RD,Lip GY

更新日期：2005-03-02 00:00:00

abstract：:Appropriate interpretation of changes in markers of kidney function is essential during the treatment of acute and chronic heart failure. Historically, kidney function was primarily assessed by serum creatinine and the calculation of estimated glomerular filtration rate. An increase in serum creatinine, also termed wo...

journal_title：European journal of heart failure

authors： Mullens W,Damman K,Testani JM,Martens P,Mueller C,Lassus J,Tang WHW,Skouri H,Verbrugge FH,Orso F,Hill L,Ural D,Lainscak M,Rossignol P,Metra M,Mebazaa A,Seferovic P,Ruschitzka F,Coats A

更新日期：2020-04-01 00:00:00

abstract：:The published version of this paper contained an error. The part C of the figure only has the header "multiple organs", whereas it must read: “HF does not affect multiple organs”. ...

journal_title：European journal of heart failure

authors：

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:We describe the baseline characteristics of subjects randomised in the largest placebo-controlled, morbidity-mortality trial to date in patients with heart failure and preserved ejection fraction - the irbesartan in heart failure with preserved systolic function trial (I-PRESERVE). METHODS AND RESULTS:4133 ...

journal_title：European journal of heart failure

authors： McMurray JJ,Carson PE,Komajda M,McKelvie R,Zile MR,Ptaszynska A,Staiger C,Donovan JM,Massie BM

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:It is not clear if long-term antithrombotic treatment has a beneficial effect on the incidence of thromboembolism in chronic heart failure (CHF). The HELAS study (Heart failure Long-term Antithrombotic Study) is a multicentre, randomised, double-blind, placebo-controlled trial to evaluate antithrombotic trea...

journal_title：European journal of heart failure

authors： Cokkinos DV,Haralabopoulos GC,Kostis JB,Toutouzas PK,HELAS investigators.

更新日期：2006-06-01 00:00:00

abstract：AIMS:To investigate the relationship between central venous pressure (CVP) at presentation to the emergency room (ER) and the risk of cardiac rehospitalization and mortality in patients with decompensated heart failure (DHF). METHODS AND RESULTS:Central venous pressure was determined non-invasively using high-resoluti...

journal_title：European journal of heart failure

authors： Uthoff H,Thalhammer C,Potocki M,Reichlin T,Noveanu M,Aschwanden M,Staub D,Arenja N,Socrates T,Twerenbold R,Mutschmann-Sanchez S,Heinisch C,Jaeger KA,Mebazaa A,Mueller C

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Crataegus preparations have been used for centuries especially in Europe. To date, no proper data on their efficacy and safety as an add-on-treatment are available. Therefore a large morbidity/mortality trial was performed. AIM:To investigate the efficacy and safety of an add-on treatment with Crataegus ext...

journal_title：European journal of heart failure

authors： Holubarsch CJ,Colucci WS,Meinertz T,Gaus W,Tendera M,Survival and Prognosis: Investigation of Crataegus Extract WS 1442 in CHF (SPICE) trial study group.

更新日期：2008-12-01 00:00:00

abstract：AIMS:Chronic hypertension may cause left ventricular hypertrophy (LVH). The role of matrix metalloproteinases (MMPs), tissue inhibitors of matrix metalloproteinases (TIMPs), and tenascin-C (Tn-C) splice variants in concentric vs. eccentric left ventricular remodelling has not been investigated. METHODS AND RESULTS:Ser...

journal_title：European journal of heart failure

authors： Franz M,Berndt A,Altendorf-Hofmann A,Fiedler N,Richter P,Schumm J,Fritzenwanger M,Figulla HR,Brehm BR

更新日期：2009-11-01 00:00:00

abstract：:Anti-beta-1-adrenergic receptor antibodies (anti-β1AR Abs) have long been implicated in the pathogenesis of dilated cardiomyopathy (DCM). It is believed that these autoantibodies bind to and constitutively stimulate the β1AR to promote pathological cardiac remodelling and β1AR desensitization and downregulation. The p...

journal_title：European journal of heart failure

authors： Patel PA,Hernandez AF

更新日期：2013-07-01 00:00:00

abstract：:Aortic stenosis (AS) is the most frequent degenerative valvular heart disease in Western countries and its prevalence increases in parallel with the ageing process of the population. Heart failure (HF), defined by the presence of reduced left ventricular ejection fraction, may be present in up to a quarter of patients...

journal_title：European journal of heart failure

authors： Kamperidis V,Delgado V,van Mieghem NM,Kappetein AP,Leon MB,Bax JJ

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Chronic heart failure (CHF) is a complex syndrome, in which reactive oxygen species and inflammatory cytokines are important stressors that contribute to the pathogenesis. AIM:We have studied physiological stress response parameters in CHF, in particular the redox-active regulator thioredoxin. SUBJECTS:A c...

journal_title：European journal of heart failure

authors： Jekell A,Hossain A,Alehagen U,Dahlström U,Rosén A

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND AIMS:The diagnosis of heart failure is an important clinical problem and yet reported diagnostic accuracy in primary care is less than 50%. We established a Rapid Access Heart Failure Clinic (RAHFC) in a district general hospital serving a population of 292,000 in SE London, UK, to diagnose and manage ne...

journal_title：European journal of heart failure

authors： Fox KF,Cowie MR,Wood DA,Coats AJ,Poole-Wilson PA,Sutton GC

更新日期：2000-12-01 00:00:00

abstract：AIMS:We evaluated the applicability and prognostic importance of oral glucose tolerance testing (OGTT) among outpatients with systolic heart failure (SHF). METHODS AND RESULTS:Consecutive patients with SHF and left ventricular ejection fraction (LVEF) ≤ 45% referred to a heart failure clinic (n= 413) were included in ...

journal_title：European journal of heart failure

authors： Egstrup M,Schou M,Gustafsson I,Kistorp CN,Hildebrandt PR,Tuxen CD

更新日期：2011-03-01 00:00:00

abstract：:Carvedilol has been shown to be beneficial for patients with heart failure, but it is not clear how it should be initiated in routine clinical practice, particularly in the elderly. This study is a retrospective review of 19 patients of age 80+/-4 years with heart failure, who had Carvedilol treatment initiated in a r...

journal_title：European journal of heart failure

authors： Owen A

更新日期：2000-09-01 00:00:00