Abstract：
BACKGROUND:Most patients suspected of having heart failure (HF) will get a 12-lead electrocardiogram (ECG) but its utility for excluding HF or assisting in its management has rarely been investigated. METHODS:The EuroHeart Failure survey identified 11,327 patients hospitalised with a suspected diagnosis of HF from 115 hospitals in 24 countries. ECGs were obtained from 9315 patients, of whom 5934 had cardiac imaging tests. The utility of the ECG was assessed for excluding or diagnosing major structural heart disease (MSHD) or major left ventricular systolic dysfunction (MLVSD) and for therapeutic decision making. FINDINGS:MSHD was present in 70% and MLVSD in 54% of patients overall but in only 21% and 5%, respectively, if the ECG was entirely normal. However, <2% of patients had a normal ECG. No single ECG characteristic identified a probability <25% of MSHD or <20% of MLVSD. Patients with QRS width >or=120 ms or anterior pathological Q-waves had a probability >80% of MSHD and >70% of MLVSD. Diagnostic models suggested that electrocardiographic criteria alone were not accurate for the diagnosis or exclusion of important heart disease in this population. However, 2468 patients (42%) had an electrocardiographic finding that should be used to guide the choice of therapy. CONCLUSIONS:A normal ECG is rare in patients with suspected HF but has limited diagnostic value in this setting. The ECG has an important role in guiding therapy.
journal_name
Eur J Heart Failjournal_title
European journal of heart failureauthors
Khan NK,Goode KM,Cleland JG,Rigby AS,Freemantle N,Eastaugh J,Clark AL,de Silva R,Calvert MJ,Swedberg K,Komajda M,Mareev V,Follath F,EuroHeart Failure Survey Investigators.doi
10.1016/j.ejheart.2006.11.003subject
Has Abstractpub_date
2007-05-01 00:00:00pages
491-501issue
5eissn
1388-9842issn
1879-0844pii
S1388-9842(06)00388-6journal_volume
9pub_type
杂志文章,多中心研究abstract：AIMS:Aldosterone activation is central to the sodium–fluid retention that marks the progression of heart failure (HF). The actions of dietary sodium restriction, a mainstay in HF management, on cardiorenal and neuroendocrine adaptations during the progression of HF are poorly understood. The study aim was to assess the...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1002/ejhf.212
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND:Patients presenting to the emergency department (ED) with acute heart failure (AHF) are at an increased risk of morbidity and mortality. The electrocardiogram (ECG) is a routine investigation in patients with AHF used to identify potential causes and/or complications. It is unclear whether 12-lead ECG charac...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1002/ejhf.561
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:Ultrastructural findings of idiopathic dilated cardiomyopathy (IDCM) include myocyte atrophy and myofilament loss, yet little is known about the vascular abnormalities present in IDCM. METHODS AND RESULTS:Patients with IDCM and controls underwent multi-slice CT to examine length and diameter of epicardial v...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/j.ejheart.2007.07.008
更新日期：2007-10-01 00:00:00
abstract：AIMS:The aim of this review is to assess the effects of exercise training on the symptoms of depression in heart failure (HF) patients. METHODS AND RESULTS:Randomized controlled trials of exercise training in patients with HF and symptoms of depression were identified. The depression data were pooled using meta-analys...
journal_title：European journal of heart failure
pub_type： 杂志文章,meta分析,评审
doi：10.1002/ejhf.101
更新日期：2014-07-01 00:00:00
abstract：AIMS:To determine whether a strategy of intensive blood pressure control reduces the risk of heart failure (HF) events consistently across the spectrum of kidney function and albuminuria. METHODS AND RESULTS:SPRINT was a randomized clinical trial in which 9361 individuals ≥50 years, at high risk for or with cardiovasc...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1002/ejhf.1971
更新日期：2020-07-21 00:00:00
abstract：AIM:Data are scant on the incidence and prognosis of heart failure (HF) with normal ejection fraction (HFNEF, EF >49%) in an acute myocardial infarction (AMI) setting. The aim of this study was to examine incidence and predictors of HFNEF during an index acute myocardial infarction (AMI) and its subsequent associations...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1002/ejhf.416
更新日期：2016-01-01 00:00:00
abstract：AIMS:Exercise oscillatory breathing (EOB) is a ventilatory abnormality that occurs in ∼20% of heart failure (HF) patients and carries a very unfavourable prognosis. Pulmonary vasoconstriction has been suggested to be involved in this disorder. We hypothesized that modulation of pulmonary vascular hypertone by oversigna...
journal_title：European journal of heart failure
pub_type： 杂志文章,随机对照试验
doi：10.1093/eurjhf/hfr147
更新日期：2012-01-01 00:00:00
abstract：:Despite the availability of a number of different classes of therapeutic agents with proven efficacy in heart failure, the clinical course of heart failure patients is characterized by a reduction in life expectancy, a progressive decline in health-related quality of life and functional status, as well as a high risk ...
journal_title：European journal of heart failure
pub_type： 杂志文章,评审
doi：10.1002/ejhf.809
更新日期：2017-06-01 00:00:00
abstract：BACKGROUND:Heart failure with preserved ejection fraction (HFpEF) is a global public health problem. Unfortunately, little is known about HFpEF across Asia. METHODS AND RESULTS:We prospectively studied clinical characteristics, echocardiographic parameters and outcomes in 1204 patients with HFpEF (left ventricular eje...
journal_title：European journal of heart failure
pub_type： 杂志文章,多中心研究
doi：10.1002/ejhf.1227
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:In heart failure (HF), changes in lung mechanics and gas diffusion are limiting factors to exercise. Their contribution to an increased exercise ventilation to CO2 production (VE/VCO2) slope is undefined. METHODS:A total of 67 stable HF patients underwent cardiopulmonary exercise and pulmonary function test...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/j.ejheart.2004.10.009
更新日期：2005-10-01 00:00:00
abstract：AIMS:Heart failure (HF) with normal or preserved left ventricular (LV) ejection fraction (HFPEF) has been reported to be associated with similar outcome as HF with reduced EF (HFREF) in registry-based and epidemiological analyses, but many of these studies excluded patients who did not have EF measurements. Conversely,...
journal_title：European journal of heart failure
pub_type： 杂志文章,meta分析
doi：10.1093/eurjhf/hfp103
更新日期：2009-09-01 00:00:00
abstract：BACKGROUND:Nuclear factor kappa B (NF-kappaB) is activated by several factors, which increase the inflammatory response, and this activation, in turn, leads to the expression of several genes such as cytokines, and may play an important role in cardiovascular diseases. AIMS:The aim of the study is to examine the effec...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/j.ejheart.2003.10.007
更新日期：2004-03-01 00:00:00
abstract：BACKGROUND:The epidemiology of heart failure in Arabia, with a population different from the West in cultural and ethnic origin, has not been studied before. AIMS:To determine the prevalence and aetiologies of symptomatic heart failure in an indigenous Arab population over a 3-year period. METHODS:All patients with h...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/s1388-9842(00)00149-5
更新日期：2001-06-01 00:00:00
abstract：AIMS:Knowledge of patient preferences is vital for delivering optimal healthcare. This study uses utility measurement to assess the preferences of heart failure (HF) patients regarding quality of life or longevity. The utility approach represents the perspective of a patient; facilitates the combination of mortality, m...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1093/eurjhf/hft071
更新日期：2013-10-01 00:00:00
abstract：:The heart failure syndrome has first been described as an emerging epidemic about 25 years ago. Today, because of a growing and ageing population, the total number of heart failure patients still continues to rise. However, the case mix of heart failure seems to be evolving. Incidence has stabilized and may even be de...
journal_title：European journal of heart failure
pub_type： 杂志文章,评审
doi：10.1002/ejhf.1858
更新日期：2020-08-01 00:00:00
abstract：AIMS:Cardiogenic shock is the leading cause of in-hospital mortality after acute myocardial infarction (MI). This study investigates the importance of age and preexisting diabetes mellitus on the incidence and prognosis of cardiogenic shock in a large group of consecutive patients with MI. METHODS AND RESULTS:Baseline...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/j.ejheart.2004.09.007
更新日期：2005-08-01 00:00:00
abstract：BACKGROUND:Plasma renin activity is normal in left ventricular dysfunction in the absence of diuretic therapy. In health there is a reciprocal relationship between renin and atrial natriuretic peptide (ANP) but a positive correlation in advanced heart failure. The relationship between renin and ANP in mild left ventric...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/s1388-9842(99)00058-6
更新日期：1999-12-01 00:00:00
abstract：BACKGROUND:Chronic heart failure (CHF) is common and is frequently managed by primary care physicians (PCPs). Despite the European Society of Cardiology (ESC) Guidelines, standard treatments for CHF are frequently underutilised, particularly in primary care. AIM:To evaluate current drug therapy for CHF in adults with ...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/j.ejheart.2004.09.003
更新日期：2004-10-01 00:00:00
abstract：AIMS:Undetected atrial fibrillation (AF) may be common in the heart failure with preserved ejection fraction (HFpEF) population, and failure to detect this may lead to the missing of opportunities to prevent associated subclinical cerebral infarctions (SCIs) and cognitive decline. METHODS AND RESULTS:We studied 1527 p...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1002/ejhf.812
更新日期：2017-10-01 00:00:00
abstract：INTRODUCTION:Atrial fibrillation (AF) is common in patients with heart failure (HF) due to left ventricular systolic dysfunction (LVSD), with conflicting prognostic data. The aim of our study was to assess the prevalence and incidence of AF in patients with HF and to determine the prognostic impact of baseline AF and t...
journal_title：European journal of heart failure
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ejheart.2006.08.004
更新日期：2007-03-01 00:00:00
abstract：AIMS:Beta-blockers (BBs) improve outcomes in heart failure. Results from the Cardiac Insufficiency Bisoprolol Study in Elderly (CIBIS-ELD) trial previously demonstrated the feasibility of heart rate, not maximum dose, as a treatment goal. In this pre-specified analysis, we investigated the prognostic value of achieved ...
journal_title：European journal of heart failure
pub_type： 杂志文章,随机对照试验
doi：10.1002/ejhf.121
更新日期：2014-08-01 00:00:00
abstract：AIMS:The proteasome prevents the intracellular accumulation of proteins and its impairment can lead to structural and functional alterations, as noted for the coronary vasculature in a previous study. Utilizing the same model, this study was designed to test the hypothesis that chronic proteasome inhibition (PSI) also ...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1093/eurjhf/hft034
更新日期：2013-06-01 00:00:00
abstract：AIMS:To characterize the prevalence and clinical relevance of malnutrition in patients undergoing transcatheter tricuspid valve edge-to-edge repair (TTVR). METHODS AND RESULTS:Overall, 86 consecutive patients (mean age 78 ± 7 years) with moderate-to-severe tricuspid regurgitation (TR) at prohibitive surgical risk were...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1002/ejhf.1752
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:To study changes in connexin, metalloproteinase and tissue inhibitor of metalloproteinase levels during tachycardia-induced cardiomyopathy (TIC). METHODS:Canine models of TIC were established by rapid right atrial pacing at 350-400 beats per min for 8 weeks in 11 dogs, six dogs acted as a sham operation grou...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/j.ejheart.2006.04.014
更新日期：2007-01-01 00:00:00
abstract：:Most treatments for chronic heart failure are effective both in preventing its onset and reducing its progression. However, statins prevent the development of heart failure, but they do not decrease morbidity and mortality in those with established heart failure. This apparent discordance cannot be explained by an eff...
journal_title：European journal of heart failure
pub_type： 杂志文章,评审
doi：10.1002/ejhf.1183
更新日期：2018-07-01 00:00:00
abstract：:Ambulatory blood pressure monitoring has established its use in the definition of white coat hypertension and monitoring of treatment of essential hypertension. Any role for ambulatory blood pressure monitoring in heart failure is not well defined. However, from the limited studies available, ambulatory blood pressure...
journal_title：European journal of heart failure
pub_type： 杂志文章,评审
doi：10.1016/j.ejheart.2004.05.010
更新日期：2005-03-02 00:00:00
abstract：AIMS:Neutrophil gelatinase-associated lipocalin (NGAL) is a measure of acute kidney injury. Renal dysfunction portends significant risk after discharge from acute heart failure (AHF). Thus, a sensitive marker of renal injury might also help to risk stratify HF patients. METHODS AND RESULTS:GALLANT [NGAL EvaLuation Alo...
journal_title：European journal of heart failure
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1093/eurjhf/hfr087
更新日期：2011-08-01 00:00:00
abstract：BACKGROUND:Supervised cardiac rehabilitation programs have been offered to patients following myocardial infarct (MI), coronary artery bypass graft surgery (CABG) and percutaneous coronary intervention (PCI) for many years. However, limited information is available on the usefulness of rehabilitation programs in chroni...
journal_title：European journal of heart failure
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ejheart.2005.05.002
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:Myocardial contractility can be altered using voltage clamp techniques by modulating amplitude and duration of the action potential resulting in enhanced calcium entry in the cell of isolated muscle strips (Non-Excitatory Currents; NEC). Extracellular electrical stimuli delivered during the absolute refracto...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/j.ejheart.2005.05.011
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) improves symptoms, left ventricular ejection fraction (LVEF) and survival in patients with heart failure and wide QRS, however, long term clinical outcome is unknown. AIMS:To identify predictors of mortality and evaluate the effects of CRT after long term follow-up. ...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/j.ejheart.2008.06.013
更新日期：2008-08-01 00:00:00
