Targeting anti-beta-1-adrenergic receptor antibodies for dilated cardiomyopathy.

abstract：BACKGROUND:Supervised cardiac rehabilitation programs have been offered to patients following myocardial infarct (MI), coronary artery bypass graft surgery (CABG) and percutaneous coronary intervention (PCI) for many years. However, limited information is available on the usefulness of rehabilitation programs in chroni...

journal_title：European journal of heart failure

authors： Jónsdóttir S,Andersen KK,Sigurosson AF,Sigurosson SB

更新日期：2006-01-01 00:00:00

abstract：AIMS:Ventricular septal rupture (VSR) became a rare mechanical complication of myocardial infarction in the era of percutaneous coronary interventions but is associated with extreme mortality in patients who present with cardiogenic shock (CS). Promising outcomes have been reported with the use of circulatory support a...

journal_title：European journal of heart failure

authors： Rob D,Špunda R,Lindner J,Rohn V,Kunstýř J,Balík M,Rulíšek J,Kopecký P,Lipš M,Šmíd O,Kovárník T,Mlejnský F,Linhart A,Bělohlávek J

更新日期：2017-05-01 00:00:00

abstract：AIMS:The prognostic value of signs of congestion in patients suspected of having chronic heart failure (CHF) is unknown. Our objectives were to define their prevalence and specificity in diagnosing CHF and to determine their prognostic value in patients in a community heart failure clinic. METHODS AND RESULTS:Analysis...

journal_title：European journal of heart failure

authors： Damy T,Kallvikbacka-Bennett A,Zhang J,Goode K,Buga L,Hobkirk J,Yassin A,Dubois-Randé JL,Hittinger L,Cleland JG,Clark AL

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Long-term prognosis of coronary artery disease (CAD) patients is worsened when stress ischemia persists on treatment, but the relationship with adverse cardiac remodelling had never been investigated. AIM:To analyze changes in blood markers of fibrosis in patients with chronic CAD exhibiting exercise ischae...

journal_title：European journal of heart failure

authors： Radauceanu A,Moulin F,Djaballah W,Marie PY,Alla F,Dousset B,Virion JM,Capiaumont J,Karcher G,Aliot E,Zannad F

更新日期：2007-04-01 00:00:00

abstract：:We investigated the hypothesis that increased intracellular [Na+]i in heart failure contributes to preservation of SR Ca2+ load which may become particularly evident at slow heart rates. [Na+]i in SBFI-loaded myocytes from rabbits with pacing-induced heart failure (PHF) was significantly higher at each frequency as co...

journal_title：European journal of heart failure

authors： Schillinger W,Teucher N,Christians C,Kohlhaas M,Sossalla S,Van Nguyen P,Schmidt AG,Schunck O,Nebendahl K,Maier LS,Zeitz O,Hasenfuss G

更新日期：2006-11-01 00:00:00

abstract：AIMS:Aldosterone activation is central to the sodium–fluid retention that marks the progression of heart failure (HF). The actions of dietary sodium restriction, a mainstay in HF management, on cardiorenal and neuroendocrine adaptations during the progression of HF are poorly understood. The study aim was to assess the...

journal_title：European journal of heart failure

authors： Miller WL,Borgeson DD,Grantham JA,Luchner A,Redfield MM,Burnett JC Jr

更新日期：2015-02-01 00:00:00

abstract：:Alternations in gut microbial composition (i.e. loss of microbial diversity or 'gut dysbiosis') have been associated with heart failure with reduced ejection fraction (HFrEF). It has also been suggested that increased chronic low-level inflammation and immune system dysregulation seen in patients with HFrEF could be r...

journal_title：European journal of heart failure

authors： Madan S,Mehra MR

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:To achieve angiogenic interaction between VEGF(165) and angiopoietin-1 (Ang-1) using a novel adenoviral bicistronic vector (Ad-Bic) encoding the two factors and delivered ex vivo using sex-mismatched human skeletal myoblasts. METHODS AND RESULTS:A myocardial infarction model was developed in 29 female pigs; ...

journal_title：European journal of heart failure

authors： Ye L,Haider HKh,Jiang S,Tan RS,Ge R,Law PK,Sim EK

更新日期：2007-01-01 00:00:00

abstract：AIMS:Patients with intestinal malabsorption may develop cardiac dysfunction the origin of which is often unclear. We sought to investigate the pathogenesis of dilated cardiomyopathy in human malabsorption. METHODS AND RESULTS:Eighteen patients with intestinal bypass as treatment for severe obesity and cardiomyopathy u...

journal_title：European journal of heart failure

authors： Frustaci A,Sabbioni E,Fortaner S,Farina M,del Torchio R,Tafani M,Morgante E,Ciriolo MR,Russo MA,Chimenti C

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Heart failure is common in diabetes and ischaemic heart disease is the most likely link. Still, it has been suggested that the relation extends beyond such disease. METHODS:7060 subjects with two or more visits in the Reykjavík Study were followed--during 30 years from 1967. All underwent oral glucose toler...

journal_title：European journal of heart failure

authors： Thrainsdottir IS,Aspelund T,Gudnason V,Malmberg K,Sigurdsson G,Thorgeirsson G,Hardarson T,Rydén L

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Plasma concentrations of atrial natriuretic peptides are correlated with atrial pressures, as are left ventricular ejection fraction and left ventricular filling abnormalities. AIMS:This study investigated the relation of atrial natriuretic peptides to both left ventricular systolic and diastolic function i...

journal_title：European journal of heart failure

authors： Wijbenga AA,Balk AH,Jonkman FA,Boomsma F,Simoons ML,Man in t Veld AJ

更新日期：1999-03-01 00:00:00

abstract：AIMS:Angiotensin receptor-neprilysin inhibitors (ARNis) acts an ARB and neprilysin inhibitor. Diabetes mellitus significantly increases the risk of cardiovascular disease and heart failure (HF). Therefore, we evaluated the effects and mechanisms of ARNi in HF with reduced ejection fraction (HFrEF) in streptozotocin-ind...

journal_title：European journal of heart failure

authors： Suematsu Y,Miura S,Goto M,Matsuo Y,Arimura T,Kuwano T,Imaizumi S,Iwata A,Yahiro E,Saku K

更新日期：2016-04-01 00:00:00

abstract：AIMS:Endothelial dysfunction has been shown to correlate with severity of congestive heart failure (CHF) and recent data suggest morphological changes of peripheral vasculature to be associated with the syndrome. We therefore investigated the hypothesis that vascular remodeling is associated with functional changes in ...

journal_title：European journal of heart failure

authors： Poelzl G,Frick M,Huegel H,Lackner B,Alber HF,Mair J,Herold M,Schwarzacher S,Pachinger O,Weidinger F

更新日期：2005-01-01 00:00:00

abstract：AIMS:Drug-induced changes in QT dispersion may be a way of detecting harmful repolarisation abnormalities for patients receiving antiarrhythmic drugs affecting ventricular repolarisation. METHODS AND RESULTS:In 463 congestive heart failure (CHF) patients enrolled in the Danish Investigations Of Arrhythmia and Mortalit...

journal_title：European journal of heart failure

authors： Brendorp B,Elming H,Jun L,Køber L,Torp-Pedersen C,DIAMOND Study Group. Danish Investigations Of Arrhythmia and Mortality On Dofetilide.

更新日期：2002-03-01 00:00:00

abstract：:We have documented a pre-junctional beta-2 adrenoceptor mediated reduction in cardiac norepinephrine spillover (CNES) in heart failure patients receiving chronic beta-blockade. Our present objective was to ascertain the consequence of this decrease for vagal heart rate (HR) regulation by determining CNES, arterial bar...

journal_title：European journal of heart failure

authors： Kubo T,Parker JD,Azevedo ER,Atchison DJ,Newton GE,Picton P,Floras JS

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:In acute heart failure syndromes (AHFS), the prognostic value of left ventricular ejection fraction (LVEF), although widely accepted, has been recently challenged. In contrast, blood pressure is increasingly gaining ground over LVEF as predictor of mortality. Therefore, it is not clear whether both LVEF and ...

journal_title：European journal of heart failure

authors： Adamopoulos C,Zannad F,Fay R,Mebazaa A,Cohen-Solal A,Guize L,Juillière Y,Alla F

更新日期：2007-09-01 00:00:00

abstract：AIMS:Guidelines recommend down-titration of loop diuretics (LD) once euvolaemia is achieved. In outpatients with heart failure (HF), we investigated LD dose changes in daily cardiology practice, agreement with guideline recommendations, predictors of successful LD down-titration and association between dose changes and...

journal_title：European journal of heart failure

authors： Kapelios CJ,Laroche C,Crespo-Leiro MG,Anker SD,Coats AJS,Díaz-Molina B,Filippatos G,Lainscak M,Maggioni AP,McDonagh T,Mebazaa A,Metra M,Moura B,Mullens W,Piepoli MF,Rosano GMC,Ruschitzka F,Seferovic PM,Lund LH,Heart

更新日期：2020-08-01 00:00:00

abstract：AIMS:To evaluate in patients with heart failure (HF) due to systolic dysfunction the occurrence of polypharmacy, alternative medicine, immunization against influenza, and patients' knowledge about their medication. METHODS AND RESULTS:Sixty-five patients, 49 men, mean age 60.5+/-12.0 years answered a confidential ques...

journal_title：European journal of heart failure

authors： Martínez-Sellés M,García Robles JA,Muñoz R,Serrano JA,Frades E,Domínguez Muñoa M,Almendral J

更新日期：2004-03-01 00:00:00

abstract：AIMS:Exercise oscillatory breathing (EOB) is a ventilatory abnormality that occurs in ∼20% of heart failure (HF) patients and carries a very unfavourable prognosis. Pulmonary vasoconstriction has been suggested to be involved in this disorder. We hypothesized that modulation of pulmonary vascular hypertone by oversigna...

journal_title：European journal of heart failure

authors： Guazzi M,Vicenzi M,Arena R

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Plasma renin activity is normal in left ventricular dysfunction in the absence of diuretic therapy. In health there is a reciprocal relationship between renin and atrial natriuretic peptide (ANP) but a positive correlation in advanced heart failure. The relationship between renin and ANP in mild left ventric...

journal_title：European journal of heart failure

authors： Dutka DP,Puri S,Strong R,Cleland JG

更新日期：1999-12-01 00:00:00

abstract：:The heart failure syndrome has first been described as an emerging epidemic about 25 years ago. Today, because of a growing and ageing population, the total number of heart failure patients still continues to rise. However, the case mix of heart failure seems to be evolving. Incidence has stabilized and may even be de...

journal_title：European journal of heart failure

authors： Groenewegen A,Rutten FH,Mosterd A,Hoes AW

更新日期：2020-08-01 00:00:00

abstract：AIMS:Heart failure (HF) patients may be at risk of prescription of potentially inappropriate medicines (PIMs) yet no disease-specific list is available to assess PIM use in this population. A Consensus Potentially Inappropriate Medicines in Heart Failure (PIMHF) list was developed, assessed, and compared with an establ...

journal_title：European journal of heart failure

authors： Bermingham M,Ryder M,Travers B,Edwards N,Lalor L,Kelly D,Gallagher J,O'Hanlon R,McDonald K,Ledwidge M

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To study changes in connexin, metalloproteinase and tissue inhibitor of metalloproteinase levels during tachycardia-induced cardiomyopathy (TIC). METHODS:Canine models of TIC were established by rapid right atrial pacing at 350-400 beats per min for 8 weeks in 11 dogs, six dogs acted as a sham operation grou...

journal_title：European journal of heart failure

authors： Zhong JQ,Zhang W,Gao H,Li Y,Zhong M,Li D,Zhang C,Zhang Y

更新日期：2007-01-01 00:00:00

abstract：AIMS:We investigated the association between quantified metabolite, lipid and lipoprotein measures and incident heart failure hospitalisation (HFH) in the elderly, and examined whether circulating metabolic measures improve HFH prediction. METHODS AND RESULTS:Overall, 80 metabolic measures from the PROspective Study o...

journal_title：European journal of heart failure

authors： Delles C,Rankin NJ,Boachie C,McConnachie A,Ford I,Kangas A,Soininen P,Trompet S,Mooijaart SP,Jukema JW,Zannad F,Ala-Korpela M,Salomaa V,Havulinna AS,Welsh P,Würtz P,Sattar N

更新日期：2018-04-01 00:00:00

abstract：AIMS:Hemochromatosis is a condition in which iron loading impairs the function of many organs, including the heart. Congestive heart failure with left ventricular dilatation is commonly found in patients with hemochromatosis. Two missense mutations (C282Y and H63D) have been shown to be responsible for the majority of ...

journal_title：European journal of heart failure

authors： Goland S,Beilinson N,Kaftouri A,Shimoni S,Caspi A,Malnick SD

更新日期：2004-08-01 00:00:00

abstract：AIMS:Growth differentiation factor-15 (GDF-15) is associated with adverse prognosis in cardiovascular (CV) and non-CV diseases. We evaluated the association of GDF-15 with CV and non-CV outcomes in the PARADIGM-HF trial. METHODS AND RESULTS:In 1935 patients with heart failure and reduced ejection fraction (HFrEF) in P...

journal_title：European journal of heart failure

authors： Bouabdallaoui N,Claggett B,Zile MR,McMurray JJV,O'Meara E,Packer M,Prescott MF,Swedberg K,Solomon SD,Rouleau JL,PARADIGM-HF Investigators and Committees.

更新日期：2018-12-01 00:00:00

abstract：:Aortic stenosis (AS) is the most frequent degenerative valvular heart disease in Western countries and its prevalence increases in parallel with the ageing process of the population. Heart failure (HF), defined by the presence of reduced left ventricular ejection fraction, may be present in up to a quarter of patients...

journal_title：European journal of heart failure

authors： Kamperidis V,Delgado V,van Mieghem NM,Kappetein AP,Leon MB,Bax JJ

更新日期：2016-05-01 00:00:00

abstract：:The TRUE-AHF is a randomized, double-blind, parallel-group, placebo-controlled trial which is evaluating the effects of a 48-h infusion of ularitide (15 ng/kg/min) on the short- and long-term clinical course of patients with acute heart failure. Noteworthy features of the study include the early enrolment of patients ...

journal_title：European journal of heart failure

authors： Packer M,Holcomb R,Abraham WT,Anker S,Dickstein K,Filippatos G,Krum H,Maggioni AP,McMurray JJV,Mebazaa A,O'Connor C,Peacock F,Ponikowski P,Ruschitzka F,van Veldhuisen DJ,Holzmeister J,TRUE-AHF Investigators and Committees

更新日期：2017-05-01 00:00:00

abstract：AIMS:It is unclear whether myocardial velocity or deformation indices of dyssynchrony are better at predicting response to cardiac resynchronization therapy (CRT). Therefore, two indices of left ventricular (LV) dyssynchrony based on myocardial velocity and deformation were compared to predict success of CRT. METHODS ...

journal_title：European journal of heart failure

authors： Mele D,Toselli T,Capasso F,Stabile G,Piacenti M,Piepoli M,Giatti S,Klersy C,Sallusti L,Ferrari R

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Chronic heart failure (CHF) is a complex syndrome, in which reactive oxygen species and inflammatory cytokines are important stressors that contribute to the pathogenesis. AIM:We have studied physiological stress response parameters in CHF, in particular the redox-active regulator thioredoxin. SUBJECTS:A c...

journal_title：European journal of heart failure

authors： Jekell A,Hossain A,Alehagen U,Dahlström U,Rosén A

更新日期：2004-12-01 00:00:00