High intracellular Na+ preserves myocardial function at low heart rates in isolated myocardium from failing hearts.

abstract：UNLABELLED:Aim Frequent ventricular premature contractions (VPCs) may cause haemodynamic deterioration and reversible left ventricular (LV) dysfunction. We aimed to clarify this mechanism. METHODS AND RESULTS:The haemodynamics, echocardiographic parameters, and plasma brain natriuretic peptide (BNP) level were assesse...

journal_title：European journal of heart failure

authors： Kuroki K,Tada H,Seo Y,Ishizu T,Igawa M,Yamasaki H,Igarashi M,Machino T,Naruse Y,Sekiguchi Y,Murakoshi N,Aonuma K

更新日期：2012-10-01 00:00:00

abstract：:This article provides information and a commentary on trials presented at the American Heart Association meeting held in November 2005, relevant to the pathophysiology, prevention and treatment of heart failure. All reports should be considered as preliminary data, as analyses may change in the final publication. In R...

journal_title：European journal of heart failure

authors： Cleland JG,Freemantle N,Coletta AP,Clark AL

更新日期：2006-01-01 00:00:00

abstract：:Patients with chronic coronary heart disease often suffer from congestive heart failure (CHF) despite multiple drug therapies. D-Ribose has been shown in animal models to improve cardiac energy metabolism and function following ischaemia. This was a prospective, double blind, randomized, crossover design study, to ass...

journal_title：European journal of heart failure

authors： Omran H,Illien S,MacCarter D,St Cyr J,Lüderitz B

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Supervised cardiac rehabilitation programs have been offered to patients following myocardial infarct (MI), coronary artery bypass graft surgery (CABG) and percutaneous coronary intervention (PCI) for many years. However, limited information is available on the usefulness of rehabilitation programs in chroni...

journal_title：European journal of heart failure

authors： Jónsdóttir S,Andersen KK,Sigurosson AF,Sigurosson SB

更新日期：2006-01-01 00:00:00

abstract：AIMS:To investigate the prognostic value of autonomic variables in patients with symptomatic chronic heart failure (HF) treated according to current recommendations. METHODS AND RESULTS:We analysed 24 h time-domain [standard deviation of all normal-to-normal RR intervals (SDNN)], frequency-domain [very low frequency a...

journal_title：European journal of heart failure

authors： La Rovere MT,Pinna GD,Maestri R,Barlera S,Bernardinangeli M,Veniani M,Nicolosi GL,Marchioli R,Tavazzi L,GISSI-HF Investigators.

更新日期：2012-12-01 00:00:00

abstract：:It is well known that atrial fibrillation can lead to heart failure, and is attributed to rapid ventricular rate (tachycardia-induced cardiomyopathy). Some recent studies suggest the possible existence of an intrinsic left-ventricular factor related to atrial fibrillation, irrespective of other elements. In order to d...

journal_title：European journal of heart failure

authors： Jourdain P,Bellorini M,Funck F,Fulla Y,Guillard N,Loiret J,Thebault B,Sadeg N,Desnos M

更新日期：2002-06-01 00:00:00

abstract：:Patients with mild-moderate chronic heart failure (CHF) often have raised levels of serum uric acid (UA). This is due, amongst other factors, to reduced UA excretion by the kidneys, which is partly explained by restriction of sodium intake and treatment with diuretics. The decline in renal function that parallels wors...

journal_title：European journal of heart failure

authors： Reyes AJ

更新日期：2005-06-01 00:00:00

abstract：:Alternations in gut microbial composition (i.e. loss of microbial diversity or 'gut dysbiosis') have been associated with heart failure with reduced ejection fraction (HFrEF). It has also been suggested that increased chronic low-level inflammation and immune system dysregulation seen in patients with HFrEF could be r...

journal_title：European journal of heart failure

authors： Madan S,Mehra MR

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:To achieve angiogenic interaction between VEGF(165) and angiopoietin-1 (Ang-1) using a novel adenoviral bicistronic vector (Ad-Bic) encoding the two factors and delivered ex vivo using sex-mismatched human skeletal myoblasts. METHODS AND RESULTS:A myocardial infarction model was developed in 29 female pigs; ...

journal_title：European journal of heart failure

authors： Ye L,Haider HKh,Jiang S,Tan RS,Ge R,Law PK,Sim EK

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) improves symptoms, left ventricular ejection fraction (LVEF) and survival in patients with heart failure and wide QRS, however, long term clinical outcome is unknown. AIMS:To identify predictors of mortality and evaluate the effects of CRT after long term follow-up. ...

journal_title：European journal of heart failure

authors： Kronborg MB,Mortensen PT,Kirkfeldt RE,Nielsen JC

更新日期：2008-08-01 00:00:00

abstract：INTRODUCTION:Atrial fibrillation (AF) is common in patients with heart failure (HF) due to left ventricular systolic dysfunction (LVSD), with conflicting prognostic data. The aim of our study was to assess the prevalence and incidence of AF in patients with HF and to determine the prognostic impact of baseline AF and t...

journal_title：European journal of heart failure

authors： Corell P,Gustafsson F,Schou M,Markenvard J,Nielsen T,Hildebrandt P

更新日期：2007-03-01 00:00:00

abstract：UNLABELLED:Experimental data have shown that rIL2 has negative inotropic properties. This has not been investigated in humans with normal left ventricular function. Seventeen consecutive renal cell carcinoma patients who received rIL2 therapy because of dissemination were analyzed before and after treatment with a low ...

journal_title：European journal of heart failure

authors： Tio RA,Nieken J,de Vries EG,Pfeiffer C,de Jongste MJ,Pieper E,Moshage H,Limburg PC,Mulder NH

更新日期：2000-06-01 00:00:00

abstract：AIMS:Randomized trials have shown that beta-blockers (BBs) reduce mortality in chronic heart failure (HF). Less data are available on the role of BBs in patients with acute HF, specifically if BBs should be continued or temporarily withdrawn. The aim of this study was to evaluate the role of BBs on in-hospital outcomes...

journal_title：European journal of heart failure

authors： Orso F,Baldasseroni S,Fabbri G,Gonzini L,Lucci D,D'Ambrosi C,Gobbi M,Lecchi G,Randazzo S,Masotti G,Tavazzi L,Maggioni AP,Italian Survey on Acute Heart Failure Investigators.

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Most patients suspected of having heart failure (HF) will get a 12-lead electrocardiogram (ECG) but its utility for excluding HF or assisting in its management has rarely been investigated. METHODS:The EuroHeart Failure survey identified 11,327 patients hospitalised with a suspected diagnosis of HF from 115...

journal_title：European journal of heart failure

authors： Khan NK,Goode KM,Cleland JG,Rigby AS,Freemantle N,Eastaugh J,Clark AL,de Silva R,Calvert MJ,Swedberg K,Komajda M,Mareev V,Follath F,EuroHeart Failure Survey Investigators.

更新日期：2007-05-01 00:00:00

abstract：:Transthyretin amyloidosis (ATTR) is a rare, yet underdiagnosed disease characterized by progressive impairment of neurologic and cardiac function due to deposition of misfolded transthyretin. Despite great efforts, such as the introduction of orthotopic liver transplant, the devastating prognosis for both variant and ...

journal_title：European journal of heart failure

authors： Müller ML,Butler J,Heidecker B

更新日期：2020-01-01 00:00:00

abstract：AIMS:ACE-inhibitors, β-blockers, implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy (CRT) improved prognosis of heart failure. We sought to analyse the long-term prognostic impact of evidence-based integrated therapeutic strategies in patients with idiopathic dilated cardiomyopathy (IDCM...

journal_title：European journal of heart failure

authors： Merlo M,Pivetta A,Pinamonti B,Stolfo D,Zecchin M,Barbati G,Di Lenarda A,Sinagra G

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:To compare the efficacy of the homeopathic Crataegus preparation Cralonin for non-inferiority to standard treatment for mild cardiac insufficiency. METHODS:Multicentre non-randomised cohort study in patients aged 50-75 years in New York Heart Association class II. Patients received Cralonin (n=110) or ACE i...

journal_title：European journal of heart failure

authors： Schröder D,Weiser M,Klein P

更新日期：2003-06-01 00:00:00

abstract：AIMS:Although pulse pressure (PP) is a recognized risk factor for various cardiovascular diseases, its association with cardiovascular outcomes in patients with heart failure with preserved ejection fraction (HFpEF) is uncertain. METHODS AND RESULTS:We enrolled 512 of 951 consecutive HFpEF patients admitted to the Kum...

journal_title：European journal of heart failure

authors： Tokitsu T,Yamamoto E,Hirata Y,Kusaka H,Fujisue K,Sueta D,Sugamura K,Sakamoto K,Tsujita K,Kaikita K,Hokimoto S,Sugiyama S,Ogawa H

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Heart failure with preserved ejection fraction (HFpEF) is a global public health problem. Unfortunately, little is known about HFpEF across Asia. METHODS AND RESULTS:We prospectively studied clinical characteristics, echocardiographic parameters and outcomes in 1204 patients with HFpEF (left ventricular eje...

journal_title：European journal of heart failure

authors： Tromp J,Teng TH,Tay WT,Hung CL,Narasimhan C,Shimizu W,Park SW,Liew HB,Ngarmukos T,Reyes EB,Siswanto BB,Yu CM,Zhang S,Yap J,MacDonald M,Ling LH,Leineweber K,Richards AM,Zile MR,Anand IS,Lam CSP,ASIAN-HF Investiga

更新日期：2019-01-01 00:00:00

abstract：AIMS:Guidelines recommend down-titration of loop diuretics (LD) once euvolaemia is achieved. In outpatients with heart failure (HF), we investigated LD dose changes in daily cardiology practice, agreement with guideline recommendations, predictors of successful LD down-titration and association between dose changes and...

journal_title：European journal of heart failure

authors： Kapelios CJ,Laroche C,Crespo-Leiro MG,Anker SD,Coats AJS,Díaz-Molina B,Filippatos G,Lainscak M,Maggioni AP,McDonagh T,Mebazaa A,Metra M,Moura B,Mullens W,Piepoli MF,Rosano GMC,Ruschitzka F,Seferovic PM,Lund LH,Heart

更新日期：2020-08-01 00:00:00

abstract：:Despite the availability of a number of different classes of therapeutic agents with proven efficacy in heart failure, the clinical course of heart failure patients is characterized by a reduction in life expectancy, a progressive decline in health-related quality of life and functional status, as well as a high risk ...

journal_title：European journal of heart failure

authors： Cowie MR,Filippatos GS,Alonso Garcia MLA,Anker SD,Baczynska A,Bloomfield DM,Borentain M,Bruins Slot K,Cronin M,Doevendans PA,El-Gazayerly A,Gimpelewicz C,Honarpour N,Janmohamed S,Janssen H,Kim AM,Lautsch D,Laws I,Lefk

更新日期：2017-06-01 00:00:00

abstract：AIMS:Galectin-3 is a prognostic heart failure (HF) biomarker that may mediate cardiac fibrosis. We examined the value of serial galectin-3 measurement for prognosis and response to therapy in chronic HF. METHODS AND RESULTS:A total of 151 subjects with LV systolic dysfunction (LVSD) were followed through 908 visits ov...

journal_title：European journal of heart failure

authors： Motiwala SR,Szymonifka J,Belcher A,Weiner RB,Baggish AL,Sluss P,Gaggin HK,Bhardwaj A,Januzzi JL

更新日期：2013-10-01 00:00:00

abstract：AIMS:Acute heart failure is a high mortality disease and its pathophysiology is not completely understood. Dipeptidyl peptidase 3 (DPP3) is a cytosolic enzyme involved in angiotensin II and enkephalins cleavage. The aim of this study was to investigate the association of circulating DPP3 (cDPP3) levels and mortality in...

journal_title：European journal of heart failure

authors： Deniau B,Rehfeld L,Santos K,Dienelt A,Azibani F,Sadoune M,Kounde PR,Samuel JL,Tolpannen H,Lassus J,Harjola VP,Vodovar N,Bergmann A,Hartmann O,Mebazaa A,Blet A

更新日期：2020-02-01 00:00:00

abstract：AIMS:To investigate temporal trends in the risk of heart failure (HF) complicating acute myocardial infarction (AMI) and to determine whether these trends differ by gender or age. METHODS AND RESULTS:The national Swedish hospital discharge and death registries from 1993 to 2004 were used to calculate age- and gender-s...

journal_title：European journal of heart failure

authors： Shafazand M,Rosengren A,Lappas G,Swedberg K,Schaufelberger M

更新日期：2011-02-01 00:00:00

abstract：AIMS:The aim of the study was to evaluate the efficacy and clinical outcome of peritoneal dialysis (PD) treatment in patients with severe refractory heart failure (HF) and chronic kidney disease (CKD). METHODS AND RESULTS:The PD treatment was performed in 118 patients [49.2% New York Heart Association (NYHA) III and 5...

journal_title：European journal of heart failure

authors： Koch M,Haastert B,Kohnle M,Rump LC,Kelm M,Trapp R,Aker S

更新日期：2012-05-01 00:00:00

abstract：:The vast majority of acute heart failure episodes are characterized by increasing symptoms and signs of congestion with volume overload. The goal of therapy in those patients is the relief of congestion through achieving a state of euvolaemia, mainly through the use of diuretic therapy. The appropriate use of diuretic...

journal_title：European journal of heart failure

authors： Mullens W,Damman K,Harjola VP,Mebazaa A,Brunner-La Rocca HP,Martens P,Testani JM,Tang WHW,Orso F,Rossignol P,Metra M,Filippatos G,Seferovic PM,Ruschitzka F,Coats AJ

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:The development of heart failure after acute myocardial infarction (AMI) has been shown to be associated with inflammation, which is positively and negatively regulated by T helper (Th) 1 and Th2 lymphocytes, respectively. Several studies have indicated that statins can improve heart function after AMI. AIM...

journal_title：European journal of heart failure

authors： Cheng X,Liao YH,Zhang J,Li B,Ge H,Yuan J,Wang M,Lu B,Liu Y,Cheng Y

更新日期：2005-12-01 00:00:00

abstract：AIMS:Heart failure (HF) with normal or preserved left ventricular (LV) ejection fraction (HFPEF) has been reported to be associated with similar outcome as HF with reduced EF (HFREF) in registry-based and epidemiological analyses, but many of these studies excluded patients who did not have EF measurements. Conversely,...

journal_title：European journal of heart failure

authors： Somaratne JB,Berry C,McMurray JJ,Poppe KK,Doughty RN,Whalley GA

更新日期：2009-09-01 00:00:00

abstract：AIMS:With improvement in survival of chronic heart failure (HF), the clinical importance of co-morbidity is increasing. The aim of this study was to assess the incidence and risk of cancer and all-cause mortality in a large Danish HF cohort. METHODS AND RESULTS:A total of 9307 outpatients with verified HF without a pr...

journal_title：European journal of heart failure

authors： Banke A,Schou M,Videbaek L,Møller JE,Torp-Pedersen C,Gustafsson F,Dahl JS,Køber L,Hildebrandt PR,Gislason GH

更新日期：2016-03-01 00:00:00

abstract：AIMS:Endothelial dysfunction has been shown to correlate with severity of congestive heart failure (CHF) and recent data suggest morphological changes of peripheral vasculature to be associated with the syndrome. We therefore investigated the hypothesis that vascular remodeling is associated with functional changes in ...

journal_title：European journal of heart failure

authors： Poelzl G,Frick M,Huegel H,Lackner B,Alber HF,Mair J,Herold M,Schwarzacher S,Pachinger O,Weidinger F

更新日期：2005-01-01 00:00:00